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Volumn 5, Issue , 2015, Pages

Opposite rheological properties of neuronal microcompartments predict axonal vulnerability in brain injury

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; AXON; BRAIN CORTEX; BRAIN INJURY; FLOW KINETICS; METABOLISM; NERVE CELL; NEURITE; PATHOLOGY; PATHOPHYSIOLOGY; RAT;

EID: 84926321405     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep09475     Document Type: Article
Times cited : (75)

References (64)
  • 1
    • 0036325856 scopus 로고    scopus 로고
    • Directionnal control of lamellipodia extension by constraining cell shape and orienting cell tractional forces
    • Parker, K. K. et al. Directionnal control of lamellipodia extension by constraining cell shape and orienting cell tractional forces. FASEB J. 16, 1195-204 (2002).
    • (2002) FASEB J. , vol.16 , pp. 1195-1204
    • Parker, K.K.1
  • 2
    • 77951582061 scopus 로고    scopus 로고
    • Linking acin dynamics and gene transcription to drive cellular motile functions
    • Olson, E. N. & Nordheim, A. Linking acin dynamics and gene transcription to drive cellular motile functions. Nat. Rev. Mol. Cell Biol. 11, 353-365 (2010).
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 353-365
    • Olson, E.N.1    Nordheim, A.2
  • 3
    • 33847742536 scopus 로고    scopus 로고
    • Regulation of ciliary beat frequency in airways: Shear stress, ATP action, and its modulation
    • Nakahari, T. Regulation of ciliary beat frequency in airways: shear stress, ATP action, and its modulation. Am. J. Physiol. Lung Cell Mol. Physiol. 292, 612-613 (2007).
    • (2007) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.292 , pp. 612-613
    • Nakahari, T.1
  • 4
    • 0021684077 scopus 로고
    • Diffuse axonal injury in head injuries caused by a fall
    • Adams, J. H. et al . Diffuse axonal injury in head injuries caused by a fall. Lancet 2, 1420-1422 (1984).
    • (1984) Lancet , vol.2 , pp. 1420-1422
    • Adams, J.H.1
  • 6
    • 84879844434 scopus 로고    scopus 로고
    • Axonal pathology in traumatic brain injury
    • Johnson, V. E., Stewart, W. & Smith, D. H. Axonal pathology in traumatic brain injury. Exp. Neurol. 246, 35-43 (2012).
    • (2012) Exp. Neurol. , vol.246 , pp. 35-43
    • Johnson, V.E.1    Stewart, W.2    Smith, D.H.3
  • 7
    • 84863012284 scopus 로고    scopus 로고
    • Axon degeneration: Molecular mechanisms of a self-destruction pathway
    • Wang, J. T., Medress, Z. A. & Barres, B. A. Axon degeneration: Molecular mechanisms of a self-destruction pathway. J. Cell Biol. 196, 7-18 (2012).
    • (2012) J. Cell Biol. , vol.196 , pp. 7-18
    • Wang, J.T.1    Medress, Z.A.2    Barres, B.A.3
  • 8
    • 47349091839 scopus 로고    scopus 로고
    • Mechanically-induced membrane poration causes axonal beading and localized cytoskeletal damage
    • Kilinc, D., Gallo, G. & Barbee, K. A. Mechanically-induced membrane poration causes axonal beading and localized cytoskeletal damage. Exp. Neurol. 212, 422-430 (2008).
    • (2008) Exp. Neurol. , vol.212 , pp. 422-430
    • Kilinc, D.1    Gallo, G.2    Barbee, K.A.3
  • 9
    • 0031017220 scopus 로고    scopus 로고
    • Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
    • Maniotis, A., Chen, C. S. & Ingber, D. E. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc. Natl. Acad. Sci. USA 94, 849-854 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 849-854
    • Maniotis, A.1    Chen, C.S.2    Ingber, D.E.3
  • 10
    • 79960664441 scopus 로고    scopus 로고
    • A possible role for integrin in diffuse axonal injury
    • Hemphill, M. A. et al. A possible role for integrin in diffuse axonal injury. PLoS ONE 6, e22899 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e22899
    • Hemphill, M.A.1
  • 11
    • 0026520614 scopus 로고
    • An immediate light microscopic response of neuronal somata, dendrites and axons to contusing concussive head injury in the rat
    • Gallyas, F., Zoltay, G. & Balás, I. An immediate light microscopic response of neuronal somata, dendrites and axons to contusing concussive head injury in the rat. Acta Neuropathol. 83, 394-401 (1992).
    • (1992) Acta Neuropathol. , vol.83 , pp. 394-401
    • Gallyas, F.1    Zoltay, G.2    Balás, I.3
  • 12
    • 0034902082 scopus 로고    scopus 로고
    • Detection of single- and double-strand DNA breaks after traumatic brain injury in rat: Comparison of labeling techniques using DNA polymerase I, the Klenow fragment of DNA polymerase I, and terminal deoxynucleotidyl transferase
    • Clarck, R. S. B. et al. Detection of single- and double-strand DNA breaks after traumatic brain injury in rat: comparison of labeling techniques using DNA polymerase I, the Klenow fragment of DNA polymerase I, and terminal deoxynucleotidyl transferase. J Neurotrauma 18, 675-689 (2001).
    • (2001) J Neurotrauma , vol.18 , pp. 675-689
    • Clarck, R.S.B.1
  • 13
    • 0031660703 scopus 로고    scopus 로고
    • Local measurements of viscoelastic parameters of adherent cell surface by magnetic bead microrheology
    • Bausch, A. R., Ziemann, F., Boulbitch, A. A., Jacobson, K. & Sackmann, E. Local measurements of viscoelastic parameters of adherent cell surface by magnetic bead microrheology. Biophys. J. 75, 2038-2049 (1998).
    • (1998) Biophys. J. , vol.75 , pp. 2038-2049
    • Bausch, A.R.1    Ziemann, F.2    Boulbitch, A.A.3    Jacobson, K.4    Sackmann, E.5
  • 15
    • 79960109499 scopus 로고    scopus 로고
    • Linear and Nonlinear Rheology of Living Cells
    • Kollmannsberger, P. & Fabry, B. Linear and Nonlinear Rheology of Living Cells. Annu Rev. Mater. Res. 41, 75-97 (2011).
    • (2011) Annu Rev. Mater. Res. , vol.41 , pp. 75-97
    • Kollmannsberger, P.1    Fabry, B.2
  • 16
    • 42749104581 scopus 로고    scopus 로고
    • Scaling the microrheology of living cells
    • Fabry, B. et al. Scaling the microrheology of living cells. Phys. Rev. Lett. 87, 148102 (2001).
    • (2001) Phys. Rev. Lett. , vol.87 , pp. 148102
    • Fabry, B.1
  • 18
    • 0038753667 scopus 로고    scopus 로고
    • Integrins in the development, function and dysfunction of the nervous system
    • Clegg, D. O., Wingerd, K. L., Hikita, S. T. & Tolhurst, E. C. Integrins in the development, function and dysfunction of the nervous system. Front. Biosci. 8, d723-50 (2003).
    • (2003) Front. Biosci. , vol.8 , pp. d723-d750
    • Clegg, D.O.1    Wingerd, K.L.2    Hikita, S.T.3    Tolhurst, E.C.4
  • 19
    • 0036682158 scopus 로고    scopus 로고
    • The integrin family of cell adhesion molecules has multiple functions within the CNS
    • Milner, R. & Campbell, I. L. The integrin family of cell adhesion molecules has multiple functions within the CNS. J. Neurosci. Res. 69, 286-91 (2002).
    • (2002) J. Neurosci. Res. , vol.69 , pp. 286-291
    • Milner, R.1    Campbell, I.L.2
  • 20
    • 84871130134 scopus 로고    scopus 로고
    • Zeta Potentials and Isoelectric Points of Biomolecules: The Effects of Ion Types and Ionic Strengths
    • Salgin, S., Salgin, U. & Bahadir, S. Zeta Potentials and Isoelectric Points of Biomolecules: The Effects of Ion Types and Ionic Strengths. Int. J. Electrochem. Sci. 7, 12404-14 (2012).
    • (2012) Int. J. Electrochem. Sci. , vol.7 , pp. 12404-12414
    • Salgin, S.1    Salgin, U.2    Bahadir, S.3
  • 22
    • 0031386328 scopus 로고    scopus 로고
    • From semi-flexible polymers to membranes: Anomalous diffusion and reptation
    • Granek, R. From semi-flexible polymers to membranes: anomalous diffusion and reptation. J. Phys. II 7, 1761-1788 (1997).
    • (1997) J. Phys. II , vol.7 , pp. 1761-1788
    • Granek, R.1
  • 23
    • 75749107907 scopus 로고    scopus 로고
    • Cell mechanics and the cytoskeleton
    • Fletcher, D. A. & Mullin, R. D. Cell mechanics and the cytoskeleton. Nature 463, 485-492 (2010).
    • (2010) Nature , vol.463 , pp. 485-492
    • Fletcher, D.A.1    Mullin, R.D.2
  • 24
    • 34347332373 scopus 로고    scopus 로고
    • Rheological properties of the eukaryotic cell cytoskeleton
    • Pullarkat, P. A., Fernandez, P. A. & Ott, A. Rheological properties of the eukaryotic cell cytoskeleton. Phys. Rep. 449, 29-53 (2007).
    • (2007) Phys. Rep. , vol.449 , pp. 29-53
    • Pullarkat, P.A.1    Fernandez, P.A.2    Ott, A.3
  • 25
    • 77952295350 scopus 로고    scopus 로고
    • Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration
    • Tang-Schomer, M. D., Patel, A. R., Baas, P. W. & Smith, D. H. Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration. FASEB J. 24, 1401-1410 (2010).
    • (2010) FASEB J. , vol.24 , pp. 1401-1410
    • Tang-Schomer, M.D.1    Patel, A.R.2    Baas, P.W.3    Smith, D.H.4
  • 26
    • 72149113585 scopus 로고    scopus 로고
    • Neural mechanobiology and neuronal vulnerability to traumatic loading
    • LaPlaca, M. C. & Prado, G. R. Neural mechanobiology and neuronal vulnerability to traumatic loading. J. Biomech. 43, 71-78 (2010).
    • (2010) J. Biomech. , vol.43 , pp. 71-78
    • LaPlaca, M.C.1    Prado, G.R.2
  • 27
    • 0000511290 scopus 로고    scopus 로고
    • Rheological constitutive equation for a model of soft glassy materials
    • Sollich, P. Rheological constitutive equation for a model of soft glassy materials. Phys. Rev. E 58, 738-59 (1998).
    • (1998) Phys. Rev. E , vol.58 , pp. 738-759
    • Sollich, P.1
  • 28
    • 0034127331 scopus 로고    scopus 로고
    • Drug-induced changes of cytoskeletal structure and mechanics in fibroblasts: An atomic force microscopy study
    • Rotsch, C. & Radmacher, M. Drug-induced changes of cytoskeletal structure and mechanics in fibroblasts: an atomic force microscopy study. Biophys. J. 78, 520-535 (2000).
    • (2000) Biophys. J. , vol.78 , pp. 520-535
    • Rotsch, C.1    Radmacher, M.2
  • 29
    • 70349482318 scopus 로고    scopus 로고
    • Neuronal intermediate filaments and neurodegenerative disorders
    • Perrot, R. & Eyer, J. Neuronal intermediate filaments and neurodegenerative disorders. Brain Res. Bull 80, 282-95 (2009).
    • (2009) Brain Res. Bull , vol.80 , pp. 282-295
    • Perrot, R.1    Eyer, J.2
  • 30
    • 0033848793 scopus 로고    scopus 로고
    • Actin disruption alters the localization of tau in the growth cones of cerebellar granule neurons
    • Zmuda, F. & Rivas, R. J. Actin disruption alters the localization of tau in the growth cones of cerebellar granule neurons. J. Cell. Sci. 113, 2797-809 (2000).
    • (2000) J. Cell. Sci. , vol.113 , pp. 2797-2809
    • Zmuda, F.1    Rivas, R.J.2
  • 31
    • 25844513869 scopus 로고    scopus 로고
    • Power-law rheology of isolated nuclei with deformation mapping of nuclear substructures
    • Dahl, K. N., Engler, A. J., Pajerowski, J. D. & Discher, D. E. Power-law rheology of isolated nuclei with deformation mapping of nuclear substructures. Biophys. J. 89, 2855-2864 (2005).
    • (2005) Biophys. J. , vol.89 , pp. 2855-2864
    • Dahl, K.N.1    Engler, A.J.2    Pajerowski, J.D.3    Discher, D.E.4
  • 32
    • 84857769496 scopus 로고    scopus 로고
    • Spatial coordination between cell and nuclear shape within micropatterned endothelial cells
    • Versaevel, M., Grevesse, T. & Gabriele, S. Spatial coordination between cell and nuclear shape within micropatterned endothelial cells. Nat. Commun. 3, 671 (2012).
    • (2012) Nat. Commun. , vol.3 , pp. 671
    • Versaevel, M.1    Grevesse, T.2    Gabriele, S.3
  • 33
    • 0029124072 scopus 로고
    • Increasing neurofilaments subunit NF-M expression reduces axonal NF-H, inhibits radial growth and results in neurofilaments accumulation in motor neurons
    • Wong, P. C. et al . Increasing neurofilaments subunit NF-M expression reduces axonal NF-H, inhibits radial growth and results in neurofilaments accumulation in motor neurons. J. Cell Biol. 130, 1413-1422 (1995).
    • (1995) J. Cell Biol. , vol.130 , pp. 1413-1422
    • Wong, P.C.1
  • 34
    • 84872796017 scopus 로고    scopus 로고
    • Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons
    • Xu, K., Zhong, G. & Zhuang, X. Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons. Science 339, 452-456 (2013).
    • (2013) Science , vol.339 , pp. 452-456
    • Xu, K.1    Zhong, G.2    Zhuang, X.3
  • 35
    • 0027533269 scopus 로고
    • Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape
    • Gittes, F., Mickey, B., Nettleton, J. & Howard, J. Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape. J. Cell Biol. 120, 923-934 (1993).
    • (1993) J. Cell Biol. , vol.120 , pp. 923-934
    • Gittes, F.1    Mickey, B.2    Nettleton, J.3    Howard, J.4
  • 36
    • 0021265440 scopus 로고
    • Regional differences in the neuronal cytoskeleton
    • Drake, P. F. & Lasek, R. J. Regional differences in the neuronal cytoskeleton. J. Neurosci. 4, 1173-1186 (1984).
    • (1984) J. Neurosci. , vol.4 , pp. 1173-1186
    • Drake, P.F.1    Lasek, R.J.2
  • 37
    • 0022651517 scopus 로고
    • Biochemical and immunological analyses of cytoskeletal domains of neurons
    • Peng, I., Binder, L. I. & Black, M. M. Biochemical and immunological analyses of cytoskeletal domains of neurons. J. Cell Biol. 102, 252-262 (1986).
    • (1986) J. Cell Biol. , vol.102 , pp. 252-262
    • Peng, I.1    Binder, L.I.2    Black, M.M.3
  • 38
    • 0001370783 scopus 로고
    • Studying the cytoskeleton of the squid giant axon
    • Plenum Publishing Corporation, N.Y.
    • Brown, A. & Lasek, J. L. Studying the cytoskeleton of the squid giant axon. Squid as experimental animals, Plenum Publishing Corporation, N.Y. 235-302 (1990).
    • (1990) Squid as Experimental Animals , pp. 235-302
    • Brown, A.1    Lasek, J.L.2
  • 39
    • 34247279846 scopus 로고    scopus 로고
    • Neurite outgrowth and branching of PC12 cells on very soft substrates sharply decreases below a threshold of substrate rigidity
    • Leach, J. B., Brown, X. Q., Jacot, J. G., DiMilla, P. A. & Wong, J. Y. Neurite outgrowth and branching of PC12 cells on very soft substrates sharply decreases below a threshold of substrate rigidity. J. Neural Eng. 4, 26-34 (2007).
    • (2007) J. Neural Eng. , vol.4 , pp. 26-34
    • Leach, J.B.1    Brown, X.Q.2    Jacot, J.G.3    DiMilla, P.A.4    Wong, J.Y.5
  • 40
    • 59549092607 scopus 로고    scopus 로고
    • Understanding sensory nerve mechanotransduction through localized elastomeric matrix control
    • Lin, Y. W., Cheng, C. M., LeDuc, P. R. & Chen, C. C. Understanding sensory nerve mechanotransduction through localized elastomeric matrix control. PLoS ONE 4, e4293 (2009).
    • (2009) PLoS ONE , vol.4 , pp. e4293
    • Lin, Y.W.1    Cheng, C.M.2    LeDuc, P.R.3    Chen, C.C.4
  • 41
    • 78149237998 scopus 로고    scopus 로고
    • The biophysics of neuronal growth
    • Franze, K. & Guck, J. The biophysics of neuronal growth. Rep. Prog. Phys. 73, 094601 (2010).
    • (2010) Rep. Prog. Phys. , vol.73 , pp. 094601
    • Franze, K.1    Guck, J.2
  • 42
    • 84880322216 scopus 로고    scopus 로고
    • Mechanics in Neuronal Development and Repair
    • Franze, K., Janmey, P. A. & Guck, J. Mechanics in Neuronal Development and Repair. Annu Rev. Biomed. Eng. 15, 227-51 (2013).
    • (2013) Annu Rev. Biomed. Eng. , vol.15 , pp. 227-251
    • Franze, K.1    Janmey, P.A.2    Guck, J.3
  • 43
    • 62449240468 scopus 로고    scopus 로고
    • Biomechanical behavior of scar tissue and uninjured skin in a porcine model
    • Corr, D. T., Gallant-Behm, C. L., Shrive, N. G. & Hart, D. A. Biomechanical behavior of scar tissue and uninjured skin in a porcine model. Wound Repair Regen. 17, 250-259 (2009).
    • (2009) Wound Repair Regen. , vol.17 , pp. 250-259
    • Corr, D.T.1    Gallant-Behm, C.L.2    Shrive, N.G.3    Hart, D.A.4
  • 44
    • 84871689254 scopus 로고    scopus 로고
    • A trial of intracranial-pressure monitoring in traumatic brain injury
    • Chesnut, R. M. et al. A trial of intracranial-pressure monitoring in traumatic brain injury. N. Engl. J. Med. 367, 2471-2481 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , pp. 2471-2481
    • Chesnut, R.M.1
  • 45
    • 84871990334 scopus 로고    scopus 로고
    • Magnetic resonance elastography reveals altered brain viscoelasticity in experimental autoimmune encephalomyelitis
    • Riek, K. et al. Magnetic resonance elastography reveals altered brain viscoelasticity in experimental autoimmune encephalomyelitis. NeuroImage 1, 81-90 (2012).
    • (2012) NeuroImage , vol.1 , pp. 81-90
    • Riek, K.1
  • 46
    • 84894062033 scopus 로고    scopus 로고
    • Micropatterning hydroxy-PAAm hydrogels and Sylgard 184 silicone elastomers with tunable elastic moduli
    • Grevesse, T., Versaevel, M., Riaz, M. & Gabriele, S. Micropatterning hydroxy-PAAm hydrogels and Sylgard 184 silicone elastomers with tunable elastic moduli. Methods Cell Biol. 121, 33-48 (2014).
    • (2014) Methods Cell Biol. , vol.121 , pp. 33-48
    • Grevesse, T.1    Versaevel, M.2    Riaz, M.3    Gabriele, S.4
  • 47
    • 84862646170 scopus 로고    scopus 로고
    • Extracellular-matrix tethering regulates stem-cell fate
    • Trappmann, B. et al. Extracellular-matrix tethering regulates stem-cell fate. Nat. Mater. 11, 642-649 (2012).
    • (2012) Nat. Mater. , vol.11 , pp. 642-649
    • Trappmann, B.1
  • 48
    • 84921654422 scopus 로고    scopus 로고
    • Interplay of matrix stiffness and protein tethering in stem cell differentiation
    • Wen, J. H. et al. Interplay of matrix stiffness and protein tethering in stem cell differentiation. Nat. Mater. 13, 979-987 (2014).
    • (2014) Nat. Mater. , vol.13 , pp. 979-987
    • Wen, J.H.1
  • 49
    • 43249095866 scopus 로고    scopus 로고
    • Cell growth in response to mechanical stiffness is affected by neuron-astroglia interactions
    • Jiang, X. et al. Cell growth in response to mechanical stiffness is affected by neuron-astroglia interactions. Open Neurosci. J. 1, 7-14 (2007).
    • (2007) Open Neurosci. J. , vol.1 , pp. 7-14
    • Jiang, X.1
  • 50
    • 19944428596 scopus 로고    scopus 로고
    • Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion
    • Yeung, T. et al. Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil. Cytoskeleton 60, 24-34 (2005).
    • (2005) Cell Motil. Cytoskeleton , vol.60 , pp. 24-34
    • Yeung, T.1
  • 51
    • 0347319161 scopus 로고    scopus 로고
    • Substrate compliance versus ligand density in cell on gel responses
    • Engler, A. et al. Substrate compliance versus ligand density in cell on gel responses. Biophys. J. 86, 317-628 (2004).
    • (2004) Biophys. J. , vol.86 , pp. 317-628
    • Engler, A.1
  • 52
    • 84875841664 scopus 로고    scopus 로고
    • A simple route to functionalize polyacrylamide gels for the independent tuning of mechanotransduction cues
    • Grevesse, T., Versaevel, M., Circelli, G., Desprez, S. & Gabriele, S. A simple route to functionalize polyacrylamide gels for the independent tuning of mechanotransduction cues. Lab Chip 13, 777-780 (2013).
    • (2013) Lab Chip , vol.13 , pp. 777-780
    • Grevesse, T.1    Versaevel, M.2    Circelli, G.3    Desprez, S.4    Gabriele, S.5
  • 53
    • 37349005914 scopus 로고    scopus 로고
    • Fibroblast adaptation and stiffness matching to soft elastic substrates
    • Solon, J., Levental, I., Sengupta, K., Georges, P. C. & Janmey, P. A. Fibroblast adaptation and stiffness matching to soft elastic substrates. Biophys. J. 93, 4453-4461 (2007).
    • (2007) Biophys. J. , vol.93 , pp. 4453-4461
    • Solon, J.1    Levental, I.2    Sengupta, K.3    Georges, P.C.4    Janmey, P.A.5
  • 54
    • 73149093868 scopus 로고    scopus 로고
    • Cell death mechanisms and modulation in traumatic brain injury
    • Stoica, B. A. & Faden, A. I. Cell death mechanisms and modulation in traumatic brain injury. Neurotherapeutics 7, 3-12 (2010).
    • (2010) Neurotherapeutics , vol.7 , pp. 3-12
    • Stoica, B.A.1    Faden, A.I.2
  • 55
    • 84880022830 scopus 로고    scopus 로고
    • Cell confinement: Putting the squeeze on the nucleus
    • Versaevel, M., Riaz, M., Grevesse, T. & Gabriele, S. Cell confinement: putting the squeeze on the nucleus. Soft Matter 9, 6665-6676 (2013).
    • (2013) Soft Matter , vol.9 , pp. 6665-6676
    • Versaevel, M.1    Riaz, M.2    Grevesse, T.3    Gabriele, S.4
  • 56
    • 84892645691 scopus 로고    scopus 로고
    • Changes induced by peripheral nerve injury in the morphology and nanomechanics of sensory neurons
    • Benzina, O. et al. Changes induced by peripheral nerve injury in the morphology and nanomechanics of sensory neurons. J. Biomed. Opt. 18, 106014 (2013).
    • (2013) J. Biomed. Opt. , vol.18 , pp. 106014
    • Benzina, O.1
  • 57
    • 79951549182 scopus 로고    scopus 로고
    • Probing mechanical adaptation of neurite outgrowth on a hydrogel material using atomic force microscopy
    • Jiang, X. J., Lin, D. C., Horkay, F. & Langrana, N. A. Probing mechanical adaptation of neurite outgrowth on a hydrogel material using atomic force microscopy. Ann. Biomed. Eng. 39, 706 (2011).
    • (2011) Ann. Biomed. Eng. , vol.39 , pp. 706
    • Jiang, X.J.1    Lin, D.C.2    Horkay, F.3    Langrana, N.A.4
  • 58
    • 80055103253 scopus 로고    scopus 로고
    • Variations in rigidity and ligand density influence neuronal response in methylcellulose-laminin hydrogels
    • Stabenfeldt, S. E. & LaPlaca, M. C. Variations in rigidity and ligand density influence neuronal response in methylcellulose-laminin hydrogels. Acta Biomater. 7, 4102-8 (2011).
    • (2011) Acta Biomater. , vol.7 , pp. 4102-4108
    • Stabenfeldt, S.E.1    LaPlaca, M.C.2
  • 59
    • 84908099277 scopus 로고    scopus 로고
    • Systematic profiling of spatiotemporal tissue and cellular stiffness in the developing brain
    • Iwashita, M., Kataoka, N., Toida, K. & Kosodo, Y. Systematic profiling of spatiotemporal tissue and cellular stiffness in the developing brain. Development 141, 3793 (2014).
    • (2014) Development , vol.141 , pp. 3793
    • Iwashita, M.1    Kataoka, N.2    Toida, K.3    Kosodo, Y.4
  • 60
    • 33845226951 scopus 로고    scopus 로고
    • Viscoelastic properties of individual glial cells and neurons in the CNS
    • Lu, Y.-B. et al. Viscoelastic properties of individual glial cells and neurons in the CNS. Proc. Natl. Acad. Sci. USA 103, 17759-17764 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 17759-17764
    • Lu, Y.-B.1
  • 62
    • 79151475790 scopus 로고    scopus 로고
    • A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding
    • Weinger, J. S., Qiu, M., Yang, G. & Kapoor, T. M. A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding. Curr. Biol. 21, 154-60 (2011).
    • (2011) Curr. Biol. , vol.21 , pp. 154-160
    • Weinger, J.S.1    Qiu, M.2    Yang, G.3    Kapoor, T.M.4
  • 63
    • 0345130877 scopus 로고
    • Erythro-9- [3-(2-Hydroxynonyl)]adenine is an inhibitor of sperm motility that blocks dynein ATPase and protein carboxylmethylase activities
    • Bouchard, P., Penningroth, S. M., Cheung, A., Gagnon, C. & Bardin, C. W. Erythro-9- [3-(2-Hydroxynonyl)]adenine is an inhibitor of sperm motility that blocks dynein ATPase and protein carboxylmethylase activities. Proc. Natl. Acad. Sci. USA 78, 1033-6 (1981).
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 1033-1036
    • Bouchard, P.1    Penningroth, S.M.2    Cheung, A.3    Gagnon, C.4    Bardin, C.W.5
  • 64
    • 0028838171 scopus 로고
    • Sensitivity to 2,5-hexanedione of neurofilaments in neuroblastoma cell line SK-N-SH increases during differentiation
    • Heijink, E., Bolhuis, P. A. & De Wolff, F. A. Sensitivity to 2,5-hexanedione of neurofilaments in neuroblastoma cell line SK-N-SH increases during differentiation. J. Neuropathol. Exp. Neurol. 54, 82-90 (1995).
    • (1995) J. Neuropathol. Exp. Neurol. , vol.54 , pp. 82-90
    • Heijink, E.1    Bolhuis, P.A.2    De Wolff, F.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.