Neurite outgrowth and branching of PC12 cells on very soft substrates sharply decreases below a threshold of substrate rigidity

Journal of Neural Engineering

Volumn 4, Issue 2, 2007, Pages 26-34

  Leach, Jennie B ^a,c   Brown, Xin Q ^a   Jacot, Jeffrey G ^a,d   Dimilla, Paul A ^a,b   Wong, Joyce Y ^a  

^a Boston University   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

^c University of Marylandw Baltimore County   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL GROWTH; ELASTIC MODULI; ENCAPSULATION; NEURAL NETWORKS; NEURONS; SUBSTRATES;

FIBRONECTIN DENSITY; NERVE TISSUE; NEURITE OUTGROWTH; NEURONAL BEHAVIOR;

TISSUE ENGINEERING;

FIBRONECTIN; LIGAND; POLYACRYLAMIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRANCHING MORPHOGENESIS; CELL STRAIN; CELL TYPE; CONTROLLED STUDY; MECHANOTRANSDUCTION; NERVE CELL; NERVE FIBER GROWTH; NEUROBIOLOGY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SAMPLE SIZE;

ANIMALS; CELL CULTURE TECHNIQUES; CELL ENLARGEMENT; COATED MATERIALS, BIOCOMPATIBLE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELASTICITY; FIBRONECTINS; HARDNESS; MECHANOTRANSDUCTION, CELLULAR; NEURITES; PC12 CELLS; RATS; SURFACE PROPERTIES; TISSUE ENGINEERING;

EID: 34247279846     PISSN: 17412560     EISSN: 17412552     Source Type: Journal    
DOI: 10.1088/1741-2560/4/2/003     Document Type: Article

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