The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM

EMBO Reports

Volumn 16, Issue 4, 2015, Pages 520-527

  Zhang, Fan ^a   Qi, Yun ^a   Zhou, Kiet ^a   Zhang, Guofeng ^b   Linask, Kaari ^a   Xu, Hong ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

Author keywords

cyclic adenosine 3 5 monophosphate; cyclic nucleotide phosphodiesterase; mitochondrial DNA; mitochondrial transcription factor A; neurodegeneration

Indexed keywords

CAMP PHOSPHODIESTERASE PRUNE; CYCLIC AMP PHOSPHODIESTERASE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; UNCLASSIFIED DRUG; CYCLIC AMP; DOUBLE STRANDED RNA; DROSOPHILA PROTEIN; GREEN FLUORESCENT PROTEIN; PHOTOPROTEIN; PN PROTEIN, DROSOPHILA; RED FLUORESCENT PROTEIN; TFAM PROTEIN, DROSOPHILA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; BIOGENESIS; CELL CULTURE; DOWN REGULATION; DROSOPHILA; ENZYME LOCALIZATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL DNA REPLICATION; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; DNA REPLICATION; DROSOPHILA MELANOGASTER; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; ORGANELLE BIOGENESIS; OXIDATIVE PHOSPHORYLATION; PROTEIN STABILITY; REPORTER GENE; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

METAZOA;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; ANIMALS; CELLS, CULTURED; CYCLIC AMP; DNA REPLICATION; DNA, MITOCHONDRIAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MITOCHONDRIA; ORGANELLE BIOGENESIS; OXIDATIVE PHOSPHORYLATION; PROTEIN STABILITY; RNA, DOUBLE-STRANDED; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84926256185     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201439636     Document Type: Article

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