Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant

Nature Genetics

Volumn 46, Issue 4, 2014, Pages 389-392

  Hill, Jahda H ^a   Chen, Zhe ^a   Xu, Hong ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

ALLELE; ANIMAL TISSUE; ARTICLE; DEVELOPMENTAL STAGE; DNA REPAIR; DNA REPLICATION; DROSOPHILA MELANOGASTER; EMBRYO; FEMALE; GENE AMPLIFICATION; GENE MUTATION; GENETIC CONSERVATION; MALE; MOLECULAR EVOLUTION; NONHUMAN; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; WILD TYPE;

DROSOPHILA MELANOGASTER;

ANIMALS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; DNA REPLICATION; DNA, MITOCHONDRIAL; DROSOPHILA MELANOGASTER; EVOLUTION, MOLECULAR; FEMALE; GENES, LETHAL; MODELS, GENETIC; OOGENESIS; SELECTION, GENETIC; TEMPERATURE; TIME FACTORS;

EID: 84898058958     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2920     Document Type: Article

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