Association of blood lead levels with urinary F2-8α isoprostane and 8-hydroxy-2-deoxy-guanosine concentrations in first-grade Uruguayan children

Environmental Research

Volumn 140, Issue , 2015, Pages 127-135

  Roy, Aditi ^a   Queirolo, Elena ^b   Peregalli, Fabiana ^b,c   Mañay, Nelly ^d   Martínez, Gabriela ^d   Kordas, Katarzyna ^a,e  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSIDAD CATÓLICA DEL URUGUAY   (Uruguay)

^c Centro Hospitalario Pereira Rossell   (Uruguay)

^d UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^e UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

8 hydroxy 2 deoxy guanosine; Child; DNA damage; Isoprostane; Lead; Lipid peroxidation; Oxidative stress; Pb; School age; Uruguay

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ASCORBIC ACID; BIOLOGICAL MARKER; ISOPROSTANE DERIVATIVE; ZINC; 8-OXO-7-HYDRODEOXYGUANOSINE; DEOXYGUANOSINE; LEAD;

BLOOD; CHILD HEALTH; CONCENTRATION (COMPOSITION); DIETARY SHIFT; HEALTH CARE; MOLECULAR ANALYSIS; TOXICITY TEST; URINE;

ARTICLE; CHILD; DIETARY INTAKE; FEMALE; HUMAN; KIDNEY CONCENTRATING CAPACITY; LEAD BLOOD LEVEL; MALE; OXIDATIVE STRESS; PRESCHOOL CHILD; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; BLOOD; ENVIRONMENTAL EXPOSURE; URINE; URUGUAY;

URUGUAY;

CHILD; DEOXYGUANOSINE; ENVIRONMENTAL EXPOSURE; F2-ISOPROSTANES; FEMALE; HUMANS; LEAD; MALE; OXIDATIVE STRESS; URUGUAY;

EID: 84926201312     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2015.03.001     Document Type: Article

References (65)

1. Ahamed M., Fareed M., Kumar A., Siddiqui W.A., Siddiqui M.K.J. Oxidative stress and neurological disorders in relation to blood lead levels in children. Redox Rep. 2008, 13:117-122.
2. Ahamed M., Mehrotra P.K., Kumar P., Siddiqui M.K.J. Placental lead-induced oxidative stress and preterm delivery. Environ. Toxicol. Pharmacol. 2009, 27:70-74.
3. Ahamed M., Siddiqui M.K.J. Low level lead exposure and oxidative stress: current opinions. Clin. Chim. Acta 2007, 383:57-64.
4. Ahamed M., Verma S., Kumar A., Siddiqui M.K.J. Environmental exposure to lead and its correlation with biochemical indices in children. Sci. Total Environ. 2005, 346:48-55.
5. Ahamed M., Verma S., Kumar A., Siddiqui M.K.J. Delta-aminolevulinic acid dehydratase inhibition and oxidative stress in relation to blood lead among urban adolescents. Hum. Exp. Toxicol. 2006, 25:547-553.
6. Basu S. F2-isoprostanes in human health and diseases: from molecular mechanisms to clinical implications. Antioxid. Redox Signal. 2008, 10:1405-1434.
7. Bellinger D.C. The protean toxicities of lead: new chapters in a familiar story. Int. J. Environ. Res. Public Health 2011, 8:2593-2628.
8. Berrahal A.A., Lasram M., El Elj N., Kerkeni A., Gharbi N., El-Fazaa S. Effect of age-dependent exposure to lead on hepatotoxicity and nephrotoxicity in male rats. Environ. Toxicol. 2011, 26:68-78.
9. Bizon A., Antonowicz-Juchniewicz J., Andrzejak R., Milnerowicz H. The influence of the intensity of smoking and years of work in the metallurgy on pro-oxidant/antioxidant balance in the blood of smelters. Toxicol. Ind. Health 2013, 29:149-161.
10. Bray T.M., Bettger W.J. The physiological role of zinc as an antioxidant. Free Radic. Biol. Med. 1990, 8(3):281-291.
11. Bushnik T., Levallois P., D'Amour M., Anderson T.J., McAlister F.A. Association between blood lead and blood pressure: results from the Canadian Health Measures Survey (2007 to 2011). Health Rep. 2014, 25(7):12-22.
12. Cabral M., Dieme D., Verdin A., Garcon G., Fall M., Bouhsina S., et al. Low-level environmental exposure to lead and renal adverse effects: a cross-sectional study in the population of children bordering the Mbeubeuss landfill near Dakar, Senegal. Hum. Exp. Toxicol. 2012, 31:1280-1291.
13. Compendio de referencias prácticas. Departamento de Alimentos, Escuela Nutrición y Dietética, Oficina del Libro FEFMUR, Montevideo, 2002.
14. deOnis M., Onyango A.W., Borghi E., Siyam A., Nishida C., Siekmann J. Development of a WHO growth reference for school-aged children and adolescence. Bull. World Health Organ. 2007, 85(9):660-667.
15. Dziaman T., Gackowski D., Rozalski R., Siomek A., Szulczynski J., Zabielski R., et al. Urinary excretion rates of 8-oxogua and 8-oxodg and antioxidant vitamins level as a measure of oxidative status in healthy, full-term newborns. Free Radic. Res. 2007, 41:997-1004.
16. Engstrom K.S., Vahter M., Johansson G., Lindh C.H., Teichert F., Singh R., et al. Chronic exposure to cadmium and arsenic strongly influences concentrations of 8-oxo-7,8-dihydro-2'-deoxyguanosine in urine. Free Radic. Biol. Med. 2010, 48:1211-1217.
17. Erhardt J.G., Estes J.E., Pfeiffer C.M., Biesalski H.K., Craft N.E. Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and c-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique. J. Nutr. 2004, 134:3127-3132.
18. Garcia-Leston J., Roma-Torres J., Vilares M., Pinto R., Prista J., Teixeira J.P., et al. Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair. Environ. Int. 2012, 43:29-36.
19. Garcon G., Leleu B., Marez T., Zerimech F., Haguenoer J.M., Furon D., et al. Biomonitoring of the adverse effects induced by the chronic exposure to lead and cadmium on kidney function: usefulness of alpha-glutathione S-transferase. Sci. Total Environ. 2007, 377:165-172.
20. Garcon G., Leleu B., Zerimech F., Marez T., Haguenoer J.M., Furon D., et al. Biologic markers of oxidative stress and nephrotoxicity as studied in biomonitoring of adverse effects of occupational exposure to lead and cadmium. J. Occup. Environ. Med. 2004, 46:1180-1186.
21. Grover P., Rekhadevi P.V., Danadevi K., Vuyyuri S.B., Mahboob M., Rahman M.F. Genotoxicity evaluation in workers occupationally exposed to lead. Int. J. Hyg. Environ. Health 2010, 213:99-106.
22. Haleagrahara N., Chakravarthi S., Kulur A.B., Radhakrishnan A. Effects of chronic lead acetate exposure on bone marrow lipid peroxidation and antioxidant enzyme activities in rats. Afr. J. Pharm. Pharmacol. 2011, 5:923-929.
23. Holt E.M., Steffen L.M., Moran A., Basu S., Steinberger J., Ross J.A., et al. Fruit and vegetable consumption and its relation to markers of inflammation and oxidative stress in adolescents. J. Am. Diet. Assoc. 2009, 109:414-421.
24. Hong Y.C., Oh S.Y., Kwon S.O., Park M.S., Kim H., Leem J.H., et al. Blood lead level modifies the association between dietary antioxidants and oxidative stress in an urban adult population. Br. J. Nutr. 2013, 109:148-154.
25. Jasso-Pineda Y., Diaz-Barriga F., Calderon J., Yanez L., Carrizales L., Perez-Maldonado I.N. DNA damage and decreased DNA repair in peripheral blood mononuclear cells in individuals exposed to arsenic and lead in a mining site. Biol. Trace Elem. Res. 2012, 146:141-149.
26. Jenkins R.R. Exercise and oxidative stress methodology: a critique. Am. J. Clin. Nutr. 2000, 72:670S-674S.
27. Jin Y.P., Liao Y.J., Lu C.W., Li G.X., Yu F., Zhi X.P., et al. Health effects in children aged 3-6 years induced by environmental lead exposure. Ecotoxicol. Environ. Saf. 2006, 63:313-317.
28. Kanaya A.M., Wassel C.L., Stoddard P.J., Harris T.B., Cummings S.R., Kritchevsky S.B., et al. F2-isoprostanes and adiposity in older adults. Obesity 2011, 19:861-867.
29. Kasperczyk A., Machnik G., Dobrakowski M., Sypniewski D., Birkner E., Kasperczyk S. Gene expression and activity of antioxidant enzymes in the blood cells of workers who were occupationally exposed to lead. Toxicology 2012, 301:79-84.
30. Kaviarasan S., Muniandy S., Qvist R., Ismail I.S. F(2)-isoprostanes as novel biomarkers for type 2 diabetes: a review. J. Clin. Biochem. Nutr. 2009, 45:1-8.
31. Khan D.A., Qayyum S., Saleem S., Khan F.A. Lead-induced oxidative stress adversely affects health of the occupational workers. Toxicol. Ind. Health 2008, 24:611-618.
32. Lee D.H., Lim J.S., Song K., Boo Y., Jacobs D.R. Graded associations of blood lead and urinary cadmium concentrations with oxidative-stress-related markers in the US population: results from the third national health and nutrition examination survey. Environ. Health Perspect. 2006, 114:350-354.
33. Lin T.S., Wu C.C., Wu J.D., Wei C.H. Oxidative DNAdamage estimated by urinary 8-hydroxy-2'-deoxyguanosine and arsenic in glass production workers. Toxicol. Ind. Health 2012, 28:513-521.
34. Llorente-Cantarero F.J., Gil-Campos M., Benitez-Sillero J.D., Munoz-Villanueva M.C., Tunez I., Perez-Navero J.L. Prepubertal children with suitable fitness and physical activity present reduced risk of oxidative stress. Free Radic. Biol. Med. 2012, 53:415-420.
35. Malekirad A.A., Oryan S., Fani A., Babapor V., Hashemi M., Baeeri M., et al. Study on clinical and biochemical toxicity biomarkers in a zinc-lead mine workers. Toxicol. Ind. Health 2010, 26:331-337.
36. Martin D., Glass T.A., Bandeen-Roche K., Todd A.C., Shi W., Schwartz B.S. Association of blood lead and tibia lead with blood pressure and hypertension in a community sample of older adults. Am. J. Epidemiol. 2006, 163(5):467-478.
37. Martinez S.A., Simonella L., Hansen C., Rivolta S., Cancela L.M., Virgolini M.B. Blood lead levels and enzymatic biomarkers of environmental lead exposure in children in cordoba, Argentina, after the ban of leaded gasoline. Hum. Exp. Toxicol. 2013, 32:449-463.
38. Mazumdar M., Bellinger D.C., Gregas M., Abanilla K., Bacic J., Needleman H.L. Low-level environmental lead exposure in childhood and adult intellectual function: a follow-up study. Environ. Health 2011, 10:24.
39. Mendez-Gomez J., Garcia-Vargas G.G., Lopez-Carrillo L., Calderon-Aranda E.S., Gomez A., Vera E., et al. Genotoxic effects of environmental exposure to arsenic and lead on children in region lagunera, mexico. Ann. N. Y. Acad. Sci. 2008, 1140:358-367.
40. Mielzynska D., Siwinska E., Kapka L., Szyfter K., Knudsen L.E., Merlo D.F. The influence of environmental exposure to complex mixtures including pahs and lead on genotoxic effects in children living in upper Silesia, Poland. Mutagenesis 2006, 21:295-304.
41. Moro A.M., Charao M., Brucker N., Bulcao R., Freitas F., Guerreiro G., et al. Effects of low-level exposure to xenobiotics present in paints on oxidative stress in workers. Sci. Total Environ. 2010, 408:4461-4467.
42. Nair N., Bedwal S., Prasad S., Saini M.R., Bedwal R.S. Short-term zinc deficiency in diet induces increased oxidative stress in testes and epididymis of rats. Indian J. Exp. Biol. 2005, 43:786-794.
43. Navas-Acien A., Guallar E., Silbergeld E.K., Rothenberg S.J. Lead exposure and cardiovascular disease-a systematic review. Environ. Health Perspect. 2007, 115:472-482.
44. Olewinska E., Kasperczyk A., Kapka L., Kozlowska A., Pawlas N., Dobrakowski M., et al. Level of DNA damage in lead-exposed workers. Ann. Agric. Environ. Med. 2010, 17:231-236. Parsons P.J. and Chisolm J.J., The Lead.
45. Parsons P.J., Chisolm J.J. The Lead Laboratory 1997, Centers for Disease Control and Prevention, Department of Health and Human Services, Atlanta, GA: U.S., Available: http://www.cdc.gov/nceh/lead/publications/1997/pdf/c1.pdf (accessed 25.11.2014.).
46. Permpongpaiboon T., Nagila A., Pidetcha P., Tuangmungsakulchai K., Tantrarongroj S., Porntadavity S. Decreased paraoxonase 1 activity and increased oxidative stress in low lead-exposed workers. Hum. Exp. Toxicol. 2011, 30:1196-1203.
47. Pollack A.Z., Schisterman E.F., Goldman L.R., Mumford S.L., Perkins N.J., Bloom M.S., et al. Relation of blood cadmium, lead, and mercury levels to biomarkers of lipid peroxidation in premenopausal women. Am. J. Epidemiol. 2012, 175:645-652.
48. Powell S.R. The antioxidant properties of zinc. J. Nutr. 2000, 130:1447S-1454S.
49. Queirolo E.I., Ettinger A.S., Stoltzfus R.J., Kordas K. Association of anemia, child and family characteristics with elevated blood lead concentrations in preschool children from Montevideo, Uruguay. Arch. Environ. Occup. Health 2010, 65:94-100.
50. Royston P., White I.R. Multiple imputation by chained equations (mice): implementation in stata. J. Stat. Softw. 2011, 45:1-20.
51. Sandhir R., Gill K.D. Effect of lead on lipid-peroxidation in liver of rats. Biol. Trace Elem. Res. 1995, 48:91-97.
52. Serafim A., Company R., Lopes B., Rosa J., Cavaco A., Castela G., et al. Assessment of essential and nonessential metals and different metal exposure biomarkers in the human placenta in a population from the south of Portugal. J. Toxicol. Environ. Health - Part A 2012, 75:867-877.
53. Song Y., Leonard S.W., Traber M.G., Ho E. Zinc deficiency affects DNA damage, oxidative stress, antioxidant defenses, and DNA repair in rats. J. Nutr. 2009, 139:1626-1631.
54. Sram R.J., Binkova B., Rossner P. Vitamin C for DNA damage prevention. Mutat. Res.: Fundam. Mol. Mech. Mutagen. 2012, 733:39-49.
55. Svecova V., Rossner P., Dostal M., Topinka J., Solansky I., Sram R.J. Urinary 8-oxodeoxyguanosine levels in children exposed to air pollutants. Mutat. Res.: Fundam. Mol. Mech. Mutagen. 2009, 662:37-43.
56. Szaflarska-Poplawska A., Siomek A., Czerwionka-Szaflarska M., Gackowski D., Rozalski R., Guz J., et al. Oxidatively damaged dna/oxidative stress in children with celiac disease. Cancer Epidemiol. Biomark. Prev. 2010, 19:1960-1965.
57. Thurnham D.I., McCabe L.D., Haldar S., Wieringa F.T., Northrop-Clewes C.A., McCabe G.P. Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis. Am. J. Clin. Nutr. 2010, 92:546-555.
58. Tomey K.M., Sowers M.R., Li X.Z., McConnell D.S., Crawford S., Gold E.B. Dietary fat subgroups, zinc, and vegetable components are related to urine F-2α-isoprostane concentration, a measure of oxidative stress, in midlife women. J. Nutr. 2007, 137:2412-2419.
59. Valavanidis A., Vlachogianni T., Fiotakis C. 8-hydroxy-2'-deoxyguanosine (8-OH-dG): a critical biomarker of oxidative stress and carcinogenes. J. Environ. Sci. Health C: Environ. Carcinog. Ecotoxicol. Rev. 2009, 27:120-139.
60. Vázquez, M., Witriw, A., 1997. Modelos Visuales de Alimentos & Tablas de Relación Peso /Volumen. 1 a Edición,Buenos Aires. pp. 1-44.
61. WHO, 2010. Anthro for personal computers, version 3.2.2, 2011: Software for assessing growth and development of the world's children. Geneva.
62. Willett W.C., Howe G.R., Kushi L.H. Adjustment for total energy intake in epidemiologic studies. Am. J. Clin. Nutr. 1997, 65:S1220-S1228.
63. Yanez L., Garcia-Nieto E., Rojas E., Carrizales L., Mejia J., Calderon J., et al. DNA damage in blood cells from children exposed to arsenic and lead in a mining area. Environ. Res. 2003, 93:231-240.
64. Yoshida R., Ogawa Y., Kasai H. Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine values measured by an ELISA correlated well with measurements by high-performance liquid chromatography with electrochemical detection. Cancer Epidemiol. Biomark. Prev. 2002, 11:1076-1081.
65. Yousef M.I., El-Hendy H.A., El-Demerdesh F.M., Elagamy El Dietary zinc deficiency induced-changes in the activity of enzymes and the levels of free radicals, lipids and protein electrophoretic behavior in growing rats. Toxicology 2002, 175(1-3):223-234.