Effect of age-dependent exposure to lead on hepatotoxicity and nephrotoxicity in male rats

Environmental Toxicology

Volumn 26, Issue 1, 2011, Pages 68-78

  Berrahal, Alya Annabi ^a   Lasram, Montassar ^a   El Elj, Naziha ^a   Kerkeni, Abdelhamid ^b   Gharbi, Najoua ^a   El Fazâa, Saloua ^a  

^a FACULTÉ DES SCIENCES DE TUNIS   (Tunisia)

^b UNIVERSITY OF MONASTIR   (Tunisia)

Author keywords

Adult; Age; Kidney; Lead; Liver; Oxidative stress; Rat; Young

Indexed keywords

ALKALINITY; AMINO ACIDS; LEAD; LIVER; OXIDATIVE STRESS; PHOSPHATASES; PLANTS (BOTANY); RATING; TOXICITY; UREA;

ADULT; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; KIDNEY; SUPEROXIDE DISMUTASE ACTIVITIES; THIOBARBITURIC ACID REACTIVE SUBSTANCES; YOUNG;

RATS;

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LEAD; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL;

BEHAVIORAL RESPONSE; BIOCHEMICAL COMPOSITION; ENZYME ACTIVITY; LEAD; OXIDATION; PHYSIOLOGICAL RESPONSE; POLLUTION EXPOSURE; RODENT; SUBLETHAL EFFECT; TOXICITY;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; KIDNEY FUNCTION; LIVER FUNCTION; LIVER TOXICITY; LONG TERM EXPOSURE; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALIA; RATTUS;

EID: 79751487619     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20530     Document Type: Article

References (82)

1. Ahamed M, Siddiqui MKJ. 2007. Low level lead exposure and oxidative stress: Current opinions. Clin Chim Acta 383: 57-64.
2. Ames BN, Cathcart R, Schwiers E, Hochstein P. 1981. Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: A hypothesis. Proc Natl Acad Sci USA 78: 6858-6862.
3. Baker TK, VanVooren HB, Smith WC, Carfagna MA. 2003. Involvement of calcium channels in the sexual dimorphism of cadmium-induced hepatotoxicity. Toxicol Lett 137: 185-192.
4. Bannon DI, Murashchik C, Zapf CR, Farfel MR, Chisoim JJJr. 1994. Graphite furnace atomic absorption spectroscopic measurement of blood lead in matrix-matched standards. Clin Chem 40: 1730-1734.
5. Bechara EJH. 1996. Oxidative stress in acute intermittent porphyria and lead poisoning may be triggered by δ-aminolevulinic acid. Braz J Med Biol Res 29: 841-851.
6. Bellinger DC. 2004. Lead. Pediatrics 113: 1016-1022.
7. Benov L, Fridovich I. 1998. Growth in iron-enriched medium partially compensates E. coli for the lack of Mn and Fe SOD. JBiol Chem 273: 10313-10316.
8. Bergmeyer HU, Scheibe P, Wahlefeld AW. 1978. Optimization of methods for aspartate aminotransferase and alanine aminotransferase. Clin Chem 24: 58-73.
9. Berrahal A, Nehdi A, Hajjaji N. 2007. Antioxidant enzymes activities and bilirubin level in adult rats treated with lead. Comp Rendus Biol 330: 581-588.
10. Beyer C.E, Steketee JD, Saphier D. 1998. Antioxidant properties of melatoninan emerging mystery. Biochem Pharmacol 56: 1265-1272.
11. Borges LP, Brandão R, Godoi B, Nogueira CW, Zeni G. 2008. Oral administration of diphenyl diselenide protects against cadmium-induced liver damage in rats. Chem Biol Int 171: 15-25.
12. Casado MF, Cecchini AL, Simao ANC, Oliveira RD, Cecchini R. 2007. Free radical-mediated pre-haemolytic injury in human red blood cells subjected to lead acetate as evaluated by chemiluminescence. Food Chem Toxicol 45: 945-952.
13. Chiba M, Shinohara A, Matsushita K, Watanabe H, Inaba Y. 1996. Indices of lead-exposure in blood and urine of lead-exposed workers and concentrations of major and trace elements and activities of SOD, GSH-Px and catalase in their blood. J Exp Med 178: 49-62.
14. Dioka CE, Orisakwe OE, Adeniyi FAA, Meludu SC. 2004. Liver and renal function tests in artisans occupationally exposed to lead in mechanic village in Nnewi, Nigeria. Int J Environ Res Public Health 1: 21-25.
15. Dotan Y, Lichtenberg D, Pinchuk I. 2004. Lipid peroxidation cannot be used as a universal criterion of oxidative stress. Prog Lipid Res 43: 200-227.
16. Doumas BT, Natson WA, Biggs HG. 1971. Albumin standards and the measurement of serum albumin with bromocresol green. Clin Chim Acta 31: 87-96.
17. Drabkin DL, Austin JH. 1932. Spectrophotometric constants for common hemoglobin derivatives in human, dog and rabbit blood. J Biol Chem 98: 719-733.
18. Dufou DR, Lott JA, Nolte FS, Gretch DR. 2000. Diagnosis and monitoring of hepatic injury. II. Recommandations for use of laboratory tests in screening, diagnosis, and monitoring. Clin Chem 46: 2050-2068.
19. El-Sokkary GH, Abdel-Rahman GH, Kamel ES. 2005. Melatonin protects against lead-induced hepatic and renal toxicity in male rats. Toxicology 213: 25-33.
20. Evans JP, Whiteman M, Tredger JM, Halliwell B. 1997. Antioxidant properties of s-adenosyl-L-methionine: A proposed addition to organ storage fluids. Free Radical Biol Med 23: 1002-1008.
21. Facchinetti F, Dawson VL, Dawson TM. 1998. Free radicals as mediators of neuronal injury. Cell Mol Neurobiol 18: 667-682.
22. Falcy M, Hesbert A, Jargot D, Protois JC, Reynier M, Schneider M, Serre P. 1998. Plomb et ses composes minéraux: Tiré à part des cahiers de notes documentaires. In: Hygiène et sécurité du travail no 170; FT no 59.
23. Fawcett JK. 1960. A rapid and precise method for the determination of urea. J Clin Pathol 13: 156-159.
24. Fisher AM, Vessey JA. 1998. Preventing lead poisoning and its consequences. Ped Nursing 24: 348-350.
25. Fossati P, Prencipe L, Berti G. 1980. Use of 3, 5-dichloro-2-hydroxybenzenesulfonic acid/4-aminophenazone chromogenic system in direct enzyme asay of uric acid in serum and urine. Clin Chem 26: 227-231.
26. Fotakis G, Timbrell JA. 2006. Role of trace elements in cadmium chloride uptake in hepatoma cell lines. Toxicol Lett 164: 97-103.
27. Fullmer CS, Edelstein S, Wasserman RH. 1985. Lead-binding properties of intestinal calcium-binding proteins. J Biol Chem 260: 6816-6819.
28. Furman A, Laleli M. 2001. Maternal and umbilical cord blood lead levels: An Istanbul study. Arch Environ Health 56: 26-28.
29. Gornall AG, Bardawill CJ, David MM. 1949. Determination of serum proteins by means of the Biuret reaction. J Biol Chem 177: 751-766.
30. Gulson BL, Jameson CW, Mahaffey KR, Mizon KJ, Law AJ, Korsh MJ, Salter MA. 1998. Relationships of lead in breast milk to lead in blood, urine, and diet of the infant and mother. Environ Health Perspect 106: 667-674.
31. Gurer H, Ercal N. 2000. Can antioxidants be beneficial in the treatment of lead poisoning? Free Radical Biol Med 29: 927-945.
32. Gurer-Orhan H, Handan US, Hilal O. 2004. Correlation between clinical indicators of lead poisoning and oxidative stress parameters in control and lead-exposed workers. Toxicology 195: 147-154.
33. Hallen PI, Jorhem L, Oskarsson A. 1995a. Placental and lactational transfer of lead in rats: A study of the lactational process and effects on offspring. Arch Toxicol 69: 596-602.
34. Hallen PI, Jorhem L, Lagerkvist B, Oskarsson A. 1995b. Lead levels in human milk and blood. Sci Total Environ 166: 149-155.
35. Halliwell B. 1995. Antioxidant characterization, methodology and mechanism. Biochem Pharm 49: 1341-1348.
36. Hanafy S, Soltan ME. 2004. Effects of vitamin E pretreatment on subacute toxicity of mixture of Co, Pb and Hg nitrate-induced nephrotoxicity in rats. Environ Toxicol Pharmacol 17: 159-167.
37. Ito Y, Niiya Y, Kurita H, Shima S, Sarai S. 1985. Serum lipid peroxide level and blood superoxide dismutase activity in workers with occupational exposure to lead. Int Arch Occup Environ Health 56: 119-127.
38. Jin Y, Liao Y, Lu C, Li G, Yu F, Zhi X, Xu J, Liu S, Liu M, Yang J. 2006. Health effects in children aged 3-6 years induced by environmental lead exposure. Ecotoxicol Environ Safety 63: 313-317.
39. Jurczuk M, Moniuszko-Jakoniuk J, Bróska MM. 2006. Involvement of some low-molecular thiols in the peroxidative mechanisms of lead and ethanol action on rat live rand kidney. Toxicology 219: 11-21.
40. Krishna MC, Russo A, Mitchell JB, Goldstein S, Dafni H, Samuni A. 1996. Do nitroxide antioxidants act as scavengers of superoxide or as superoxide dismutase mimics? J Biol Chem 271: 26026-26031.
41. Lanphear BP, Hornung R, Ho M, Howard CR, Eberle S, Knauf K. 2002. Environmental lead exposure during early childhood. J Pediatr 140: 40-47.
42. Larsen K. 1972. Creatinine assay by a reaction-kinetic principle. Clin Chim Acta 41: 209-217.
43. Lawton LJ, Donaldson WE. 1991. Lead-induced tissue fatty acid alterations and lipid peroxidation. Biol Trace Elem Res 28: 83-97.
44. Li PJ, Sheng YZ, Wang QY, Gu LY, Wang YL. 2000. Transfer of lead via placenta and breast milk in human. Biomed Environ Sci 13: 85-89.
45. Lidsky TI, Schneider JS. 2003. Lead neurotoxicity in children: Basic mechanisms and clinical correlates. Brain 126: 5-19.
46. Massó EL, Corredor L, Antonio MT. 2007. Oxidative damage in liver after perinatal intoxication with lead and/or cadmium. J Trace Elem Med Biol 21: 210-216.
47. Matés JM, Pérez-Gomez C, Núňez de Castro I. 1999. Antioxidant enzymes and human diseases. Clin Biochem 32: 595-603.
48. McGowan C, Donaldson WE. 1986. Changes in organ nonprotein sufhydryl and glutathione concentrations during acute and chronic administration of inorganic lead to chicks. Biol Trace Elem Res 10: 37-46.
49. Miao-Lin H. 1994. Measurement of protein thiol groups and glutathione in plasma. Meth Enzymol 233: 380-383.
50. Misra HP, Fridovich I. 1972. The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 247: 3170-3175.
51. Monterio HP, Abdalla DSP, Arcuri AS, Bechara EJH. 1985. Oxygen toxicity related to exposure to lead. Clin Chem 31: 1673-1676.
52. Monterio HP, Bechara EJH, Abdalla DSP. 1991. Free radicals involvement in neurological porphyries and lead poisoning. Mol Cell Biochem 103: 73-83.
53. Moss DW. 1982. Alkaline phosphatase isoenzymes. Clin Chem 28: 2007-2016.
54. Mousa HM, Al-Qarawi AA, Ali BH, Rahman HAA, El Mougy SA. 2002. Effect of lead exposure on the erythrocytic antioxidant levels in goats. J Vet Med 49: 531-534.
55. Mushak P. 1991. Gastro-intestinal absorption of lead in children and adults: Overview of biological and biophysico-chemical aspects. Chem Speciation Bioavailab 3: 87-104.
56. Mushak P. 1992. Defining lead as the premier environmental health issue for children in America: Criteria and their quantitative application. Environ Res 59: 281-309.
57. Needleman H. 1990. The long term effects of exposure to low doses of lead in childhood: The Port Pirie cohort study. J Am Med Assoc 332: 83-88.
58. Needleman HL, Bellinger D. 1991. The health effect of low level exposure to lead. Annu Rev Publ Health 12: 111-140.
59. Nohl H, Gille L, Kozlov AV. 1998. Antioxidant-derived prooxidant formation from ubiquinol. Free Radical Biol Med 25: 666-675.
60. Oteiza PI, Olin KL, Fraga CG, Keen CL. 1995. Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes. J Nutr 125: 823-829.
61. Patra RC, Swarup D, Dwivedi SK. 2001. Antioxidant effects of α tocopherol, ascorbic acid and L-methionine on lead induced oxidative stress to the liver, kidney and brain in rats. Toxicology 162: 81-88.
62. Price CP, Woodman DD. 1971. An improved autoanalyzer technique for the determination of serum alkaline phosphatase. Clin Chim Acta 35: 265-271.
63. Rahman S, Sultana S. 2006. Chemopreventive activity of glycyrrhizin on lead acetate mediated hepatic oxidative stress and its hyperproliferative activity in Wistar rats. Chem Biol Int 160: 61-69.
64. Ribarov SR, Bochev PG. 1982. Lead-hemoglobin interaction as a possible source of reactive oxygen species, a chemiluminescent study. Arch Biochem Biophys 213: 288-292.
65. Rikans LE, Yamano T. 2000. Mechanisms of cadmium mediated-acute hepatotoxicity. J Biochem Mol Toxicol 14: 110-117.
66. Ronis MJJ, Badger TM, Shema SJ, Roberson PK. 1998. Endocrine mechanisms underlying the growth effects of developmental lead exposure in the rat. J Toxicol Environ Health A 54: 101-120.
67. Rosalki SB, Foo A. 1984. Two new methods for separating and quantifying bone and liver alkaline phosphatase isoenzymes in plasma. Clin Chem 30: 1182-1186.
68. Sandhir R, Julka D, Gill KD. 1994. Lipoperoxidative damage on lead exposure in rat brain and its complications on membrane bound enzymes. Pharmacol Toxicol 74: 66-71.
69. Shafiq-ur-Rehman S, Rehman S, Chandra O, Abdulla M. 1995. Evaluation of malondialdehyde as an index of lead damage in rat brain homogenates. Biometals 8: 275-279.
70. Shaikh ZA, Zaman K, Tang W, Vu T. 1999. Treatment of chronic cadmium nephrotoxicity by N-acetyl cysteine. Toxicol Lett 104: 137-142.
71. Shalan MG, Mostafa MS, Hassouna MM, El-Nabi SE, El-Rafaie A. 2005. Amelioration of lead toxicity on rat liver with vitamin C and silymarin supplements. Toxicology 206: 1-15.
72. Silbergeld EK. 2003. Facilitative mechanisms of lead as a carcinogen. Mutat Res 533: 121-133.
73. Sivaprasad R, Nagaray M, Varalakshmi P. 2004. Combined efficacies of lipoic acid and 2, 3-dimercaptosuccinic acid against lead-induced lipid peroxidation in rat liver. J Nutr Biochem 15: 18-23.
74. Solliway BM, Schaffer A, Pratt H, Yannai S. 1996. Effects of exposure to lead on selected biochemical and hematological variables. Pharmacol Toxicol 78: 18-22.
75. Tamagno E, Aragno M, Boccuzzi G, Gallo M, Parolav S, Fubini B, Poli G, Danni O. 1998. Oxygen free radical scavenger properties of dehydroepiandrosterone. Cell Biochem Funct 16: 57-63.
76. Tong S, McMichael AJ. 1999. The magnitude, persistence and public health significance of cognitive effects of environmental lead exposure in childhood. J Environ Med 1: 103-110.
77. Valle BL, Ulmer DD. 1972. Biochemical effects of mercury, cadmium and lead. Annu Rev Biochem 41: 91-128.
78. Wicox MD. 1996. Abnormal serum uric acid levels in children. J Pediatr 128: 731-741.
79. Yamano T, De Cicco LA, Rikans LE. 2000. Attenuation of cadmium-induced liver injury in senescent male Fischer 344 rats: Role of kupfer cells and inflammatory cytokines. Toxicol Appl Pharmacol 162: 68-75.
80. Yaping J, Yingjun L, Chunwei L, Gexin L, Fei Y, Xuping Z, Jianhong L, Shaoxia X, Meimei L, Jun Y. 2006. Health effects in children aged 3-6 years induced by environmental lead exposure. Ecotox Environ Saf 63: 313-317.
81. Yiin SJ, Lin TH. 1995. Lead-catalyzed peroxidation of essential unsaturated fatty acid. Biol Trace Elem 50: 67-172.
82. 2+ ATPase activities and lipid peroxidation in blood of workers. Int J Toxicol 22: 95-97.