메뉴 건너뛰기




Volumn 9, Issue 4, 2015, Pages 343-358

Management of diabetic nephropathy: Recent progress and future perspective

Author keywords

Albuminuria; Diabetic nephropathy; Hypertension; Renin angiotensin aldosterone system

Indexed keywords

COMPLICATION; DIABETIC NEPHROPATHIES; DISEASE COURSE; DISEASE MANAGEMENT; HUMAN; NON INSULIN DEPENDENT DIABETES MELLITUS; PROGNOSIS;

EID: 84926196565     PISSN: 18714021     EISSN: 18780334     Source Type: Journal    
DOI: 10.1016/j.dsx.2015.02.008     Document Type: Review
Times cited : (136)

References (150)
  • 1
    • 79959936188 scopus 로고    scopus 로고
    • National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: Systemic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants
    • Burden Of Metabolic Risk Factors Of Chronic Diseases Collaborating Group (blood Glucose) G.
    • G. Danaei, M.M. Finucane, Y. Lu, G.M. Singh, M.J. Cowan, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Glucose), and et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systemic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants Lancet 378 2011 31 40
    • (2011) Lancet , vol.378 , pp. 31-40
    • Danaei, G.1    Finucane, M.M.2    Lu, Y.3    Singh, G.M.4    Cowan, M.J.5    Al, E.6
  • 2
    • 76749103329 scopus 로고    scopus 로고
    • Diabetic kidney disease: Act now or pay later
    • R.C. Alkins, and P. Zimmet Diabetic kidney disease: act now or pay later Kidney Int 77 2010 375 377
    • (2010) Kidney Int , vol.77 , pp. 375-377
    • Alkins, R.C.1    Zimmet, P.2
  • 3
    • 84865223234 scopus 로고    scopus 로고
    • Diabetes: Treating diabetic nephropathy-still an unresolved issue
    • M.E. Cooper Diabetes: treating diabetic nephropathy-still an unresolved issue Nat Rev Endocrinol 8 2012 515 516
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 515-516
    • Cooper, M.E.1
  • 5
    • 0027378455 scopus 로고
    • Glomerular structure and function in proteinuric type 2 (non-insulin-dependent) diabetic patients
    • R. Osterby, M. Gall, A. Schmitz, F.S. Nielsen, G. Nyberg, and H. Parving Glomerular structure and function in proteinuric type 2 (non-insulin-dependent) diabetic patients Diabetology 36 1993 1064 1070
    • (1993) Diabetology , vol.36 , pp. 1064-1070
    • Osterby, R.1    Gall, M.2    Schmitz, A.3    Nielsen, F.S.4    Nyberg, G.5    Parving, H.6
  • 6
    • 33845760213 scopus 로고    scopus 로고
    • KDOQ1 clinical practice guidelines and clinical practice recommendations for diabetes and chronic kidney disease
    • National Kidney Foundation KDOQ1 clinical practice guidelines and clinical practice recommendations for diabetes and chronic kidney disease Am J Kidney Dis 49 Suppl. 2 2007 S1 S180
    • (2007) Am J Kidney Dis , vol.49 , pp. S1-S180
    • Kidney Foundation, N.1
  • 7
    • 0021236983 scopus 로고
    • Predicting diabetic nephropathy in insulin-dependent patients
    • C.E. Mogensen, and C.K. Christensen Predicting diabetic nephropathy in insulin-dependent patients N Engl J Med 311 1984 89 93
    • (1984) N Engl J Med , vol.311 , pp. 89-93
    • Mogensen, C.E.1    Christensen, C.K.2
  • 8
    • 0019944871 scopus 로고
    • Early detection of patients at risk of developing diabetic nephropathy: A longitudinal study of urinary albumin excretion
    • H.H. Parving, B. Oxenboll, P.A. Svendsen, J.S. Christiansen, and A.R. Andersen Early detection of patients at risk of developing diabetic nephropathy: a longitudinal study of urinary albumin excretion Acta Endocrinol (Copenh) 100 1982 550 552
    • (1982) Acta Endocrinol (Copenh) , vol.100 , pp. 550-552
    • Parving, H.H.1    Oxenboll, B.2    Svendsen, P.A.3    Christiansen, J.S.4    Andersen, A.R.5
  • 9
    • 0020045025 scopus 로고
    • Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus
    • G.C. Viberti, R.D. Hill, R.J. Jarrett, A. Argyropoulos, U. Mahmud, and H. Keen Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus Lancet 1 1982 1430 1432
    • (1982) Lancet , vol.1 , pp. 1430-1432
    • Viberti, G.C.1    Hill, R.D.2    Jarrett, R.J.3    Argyropoulos, A.4    Mahmud, U.5    Keen, H.6
  • 10
    • 0021322084 scopus 로고
    • Microalbuminuria predicts clinical proteinuria and early mortality in maturity onset diabetes
    • C.E. Mogensen Microalbuminuria predicts clinical proteinuria and early mortality in maturity onset diabetes N Engl J Med 310 1984 356 360
    • (1984) N Engl J Med , vol.310 , pp. 356-360
    • Mogensen, C.E.1
  • 12
    • 2342630408 scopus 로고    scopus 로고
    • Predictors for the development of microalbuminuria and macroalbuminuria in patients with type 1 diabetes: Inception cohort study
    • P. Hovind, L. Tarnow, P. Rossing, B.R. Jensen, M. Graae, I. Torp, and et al. Predictors for the development of microalbuminuria and macroalbuminuria in patients with type 1 diabetes: inception cohort study BMJ 328 2004 1105 1108
    • (2004) BMJ , vol.328 , pp. 1105-1108
    • Hovind, P.1    Tarnow, L.2    Rossing, P.3    Jensen, B.R.4    Graae, M.5    Torp, I.6
  • 13
    • 0037213037 scopus 로고    scopus 로고
    • Development and progression of nephropathy in type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS 64)
    • A.I. Adler, R.J. Stevens, S.E. Manley, R.W. Bilous, C.A. Cull, and R.R. Holman Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64) Kidney Int 63 2003 225 232
    • (2003) Kidney Int , vol.63 , pp. 225-232
    • Adler, A.I.1    Stevens, R.J.2    Manley, S.E.3    Bilous, R.W.4    Cull, C.A.5    Holman, R.R.6
  • 14
    • 0034708947 scopus 로고    scopus 로고
    • The risk of cardiovascular disease mortality associated with microalbuminuria and gross proteinuria in persons with older-onset diabetes mellitus
    • C.T. Valmadrid, R. Klein, S.E. Moss, and B.E. Klein The risk of cardiovascular disease mortality associated with microalbuminuria and gross proteinuria in persons with older-onset diabetes mellitus Arch Intern Med 160 2000 1093 1100
    • (2000) Arch Intern Med , vol.160 , pp. 1093-1100
    • Valmadrid, C.T.1    Klein, R.2    Moss, S.E.3    Klein, B.E.4
  • 15
    • 5444225600 scopus 로고    scopus 로고
    • Microalbuminuria and cardiovascular risk
    • J. Karalliedde, and G. Viberti Microalbuminuria and cardiovascular risk Am J Hypertens 17 2004 986 993
    • (2004) Am J Hypertens , vol.17 , pp. 986-993
    • Karalliedde, J.1    Viberti, G.2
  • 16
    • 0028471243 scopus 로고
    • Glomerular hyperfiltration in human diabetes
    • C.E. Mogensen Glomerular hyperfiltration in human diabetes Diabetes Care 17 1994 770 775
    • (1994) Diabetes Care , vol.17 , pp. 770-775
    • Mogensen, C.E.1
  • 18
    • 19944368397 scopus 로고    scopus 로고
    • Using serum creatinine to estimate glomerular filtration rate: Accuracy in good health and in chronic kidney disease
    • A.D. Rule, T.S. Larson, E.J. Bergstralh, J.M. Slezak, S.J. Jacobsen, and F.G. Cosio Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease Ann Intern Med 141 2004 929 937
    • (2004) Ann Intern Med , vol.141 , pp. 929-937
    • Rule, A.D.1    Larson, T.S.2    Bergstralh, E.J.3    Slezak, J.M.4    Jacobsen, S.J.5    Cosio, F.G.6
  • 19
    • 17944394870 scopus 로고    scopus 로고
    • Hyperfiltration in patients with type i diabetes mellitus: A prevalence study
    • P. Cotroneo, A. Manto, L. Todaro, A. Manto Jr., D. Pitocco, C. Saponara, and et al. Hyperfiltration in patients with type I diabetes mellitus: a prevalence study Clin Nephrol 50 1998 214 217
    • (1998) Clin Nephrol , vol.50 , pp. 214-217
    • Cotroneo, P.1    Manto, A.2    Todaro, L.3    Manto, A.4    Pitocco, D.5    Saponara, C.6
  • 20
    • 0032989007 scopus 로고    scopus 로고
    • Microalbuminuria, blood pressure and diabetic renal disease: Origin and development of ideas
    • C.E. Mogensen Microalbuminuria, blood pressure and diabetic renal disease: origin and development of ideas Diabetologia 42 1999 263 285
    • (1999) Diabetologia , vol.42 , pp. 263-285
    • Mogensen, C.E.1
  • 21
  • 22
    • 61449183458 scopus 로고    scopus 로고
    • Is hyperfiltration associated with the future risk of developing diabetic nephropathy? A meta-analysis
    • G. Magee, R. Bilous, C. Cardwell, S. Hunter, F. Kee, and D. Fogarty Is hyperfiltration associated with the future risk of developing diabetic nephropathy? A meta-analysis Diabetologia 52 2009 691 697
    • (2009) Diabetologia , vol.52 , pp. 691-697
    • Magee, G.1    Bilous, R.2    Cardwell, C.3    Hunter, S.4    Kee, F.5    Fogarty, D.6
  • 24
    • 59849097777 scopus 로고    scopus 로고
    • Insights into the regulation of renal hemodynamic function in diabetic mellitus
    • D. Cherney, J. Scholey, and J. Miller Insights into the regulation of renal hemodynamic function in diabetic mellitus Curr Diabetes Rev 4 2008 280 290
    • (2008) Curr Diabetes Rev , vol.4 , pp. 280-290
    • Cherney, D.1    Scholey, J.2    Miller, J.3
  • 25
    • 0037068623 scopus 로고    scopus 로고
    • Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes
    • E. Lurbe, J. Redon, and A. Kesani Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes N Engl J Med 347 2002 797 805
    • (2002) N Engl J Med , vol.347 , pp. 797-805
    • Lurbe, E.1    Redon, J.2    Kesani, A.3
  • 26
  • 27
    • 0026530073 scopus 로고
    • Prognostic significance of microalbuminuria in insulin-dependent diabetes mellitus: A twenty-three year follow-up study
    • J.W. Messent, T.G. Elliott, R.D. Hill, R.J. Jarrett, H. Keen, and G.C. Viberti Prognostic significance of microalbuminuria in insulin-dependent diabetes mellitus: a twenty-three year follow-up study Kidney Int 41 1992 836 839
    • (1992) Kidney Int , vol.41 , pp. 836-839
    • Messent, J.W.1    Elliott, T.G.2    Hill, R.D.3    Jarrett, R.J.4    Keen, H.5    Viberti, G.C.6
  • 28
    • 0033850165 scopus 로고    scopus 로고
    • The need for early predictors of diabetic nephropathy risk: Is albumin excretion rate sufficient?
    • M.L. Caramori, P. Fioretto, and T. Mauer The need for early predictors of diabetic nephropathy risk: is albumin excretion rate sufficient? Diabetes 49 2000 1399 1408
    • (2000) Diabetes , vol.49 , pp. 1399-1408
    • Caramori, M.L.1    Fioretto, P.2    Mauer, T.3
  • 29
    • 41349110662 scopus 로고    scopus 로고
    • Mechanisms of disease: The hypoxic tubular hypothesis of diabetic nephropathy
    • D.K. Singh, P. Winocour, and K. Farrington Mechanisms of disease: the hypoxic tubular hypothesis of diabetic nephropathy Nat Clin Pract Nephrol 4 2008 216 226
    • (2008) Nat Clin Pract Nephrol , vol.4 , pp. 216-226
    • Singh, D.K.1    Winocour, P.2    Farrington, K.3
  • 30
    • 20444502610 scopus 로고    scopus 로고
    • The podocyte: A major player in the development of diabetic nephropathy?
    • S.M. Marshall The podocyte: a major player in the development of diabetic nephropathy? Horm Metab Res 37 Suppl. 1 2005 9 16
    • (2005) Horm Metab Res , vol.37 , pp. 9-16
    • Marshall, S.M.1
  • 31
    • 1042302788 scopus 로고    scopus 로고
    • Nephropathy in diabetes (position statement)
    • American Diabetes Association Nephropathy in diabetes (position statement) Diabetes Care 27 Suppl. 1 2004 S79 S83
    • (2004) Diabetes Care , vol.27 , pp. S79-S83
    • Diabetes Association, A.1
  • 32
    • 0028149357 scopus 로고
    • Microalbuminuria is not rare before 5 years of IDDM EURODIAB IDDM Complications Study Group and the WHO Multinational Study of Vascular Disease in Diabetes Study Group
    • J.M. Stephenson, and J.H. Fuller Microalbuminuria is not rare before 5 years of IDDM EURODIAB IDDM Complications Study Group and the WHO Multinational Study of Vascular Disease in Diabetes Study Group J Diabetes Complic 8 1994 166 173
    • (1994) J Diabetes Complic , vol.8 , pp. 166-173
    • Stephenson, J.M.1    Fuller, J.H.2
  • 33
    • 0032974878 scopus 로고    scopus 로고
    • Microalbuminuria prevalence varies with age, sex, and puberty in children with type 1 diabetes followed from diagnosis in a longitudinal study. Oxford Regional Prospective Study Group
    • C.J. Schultz, T. Konopelska-Bahu, R.N. Dalton, T.A. Carroll, I. Stratton, E.A. Gale, and et al. Microalbuminuria prevalence varies with age, sex, and puberty in children with type 1 diabetes followed from diagnosis in a longitudinal study. Oxford Regional Prospective Study Group Diabetes Care 22 1999 495 502
    • (1999) Diabetes Care , vol.22 , pp. 495-502
    • Schultz, C.J.1    Konopelska-Bahu, T.2    Dalton, R.N.3    Carroll, T.A.4    Stratton, I.5    Gale, E.A.6
  • 34
    • 0345505677 scopus 로고    scopus 로고
    • Low glomerular filtration rate in normoalbuminuric type 1 diabetic patients is associated with more diabetic lesions
    • M.L. Caramori, P. Fioretto, and M. Mauer Low glomerular filtration rate in normoalbuminuric type 1 diabetic patients is associated with more diabetic lesions Diabetes 52 2003 1036 1040
    • (2003) Diabetes , vol.52 , pp. 1036-1040
    • Caramori, M.L.1    Fioretto, P.2    Mauer, M.3
  • 36
    • 0038506499 scopus 로고    scopus 로고
    • Renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetes mellitus
    • H.J. Kramer, Q.D. Nguyen, G. Curhan, and C.Y. Hsu Renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetes mellitus JAMA 289 2003 3273 3277
    • (2003) JAMA , vol.289 , pp. 3273-3277
    • Kramer, H.J.1    Nguyen, Q.D.2    Curhan, G.3    Hsu, C.Y.4
  • 37
    • 72949106696 scopus 로고    scopus 로고
    • In patients with type 1 diabetes and new-onset microalbuminuria the development of advanced chronic kidney disease may not require progression to proteinuria
    • [PMID: ]
    • B.A. Perkins, L.H. Ficociello, B. Roshan, J.H. Warram, and A.S. Krolewski In patients with type 1 diabetes and new-onset microalbuminuria the development of advanced chronic kidney disease may not require progression to proteinuria Kidney Int 77 2010 57 64 10.1038/ki.2009.399 [PMID: 19847154 ]
    • (2010) Kidney Int , vol.77 , pp. 57-64
    • Perkins, B.A.1    Ficociello, L.H.2    Roshan, B.3    Warram, J.H.4    Krolewski, A.S.5
  • 38
    • 0028556832 scopus 로고
    • Glomerular structure in non-proteinuric IDDM patients with various levels of albuminuria
    • [PMID: 7926312]
    • P. Fioretto, M.W. Steffes, and M. Mauer Glomerular structure in non-proteinuric IDDM patients with various levels of albuminuria Diabetes 43 1994 1358 1364 10.2337/diab.43.11.1358 [PMID: 7926312]
    • (1994) Diabetes , vol.43 , pp. 1358-1364
    • Fioretto, P.1    Steffes, M.W.2    Mauer, M.3
  • 39
    • 0026442320 scopus 로고
    • Serum creatinine as an index of renal function: New insights into old concept
    • [PMID: 1394976]
    • R.D. Perrone, N.E. Madias, and A.S. Levey Serum creatinine as an index of renal function: new insights into old concept Clin Chem 38 1992 1933 1953 [PMID: 1394976]
    • (1992) Clin Chem , vol.38 , pp. 1933-1953
    • Perrone, R.D.1    Madias, N.E.2    Levey, A.S.3
  • 42
    • 77949554925 scopus 로고    scopus 로고
    • Estimating GFR using the CKD Epidemiology Collaboration (CKD-EPI) creatinine equation: More accurate GFR estimates, lower CKD prevalence estimates, and better risk predictions
    • A.S. Levey, and L.A. Stevens Estimating GFR using the CKD Epidemiology Collaboration (CKD-EPI) creatinine equation: more accurate GFR estimates, lower CKD prevalence estimates, and better risk predictions Am J Kidney Dis 55 2010 622 627
    • (2010) Am J Kidney Dis , vol.55 , pp. 622-627
    • Levey, A.S.1    Stevens, L.A.2
  • 43
    • 84898869053 scopus 로고    scopus 로고
    • KDOQI US commentary on the 2012 KDIGO clinical practice guideline for the evaluation and management of CKD
    • L.A. Inker, B.C. Astor, C.H. Fox, T. Isakova, J.P. Lash, C.A. Peralta, and et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for the evaluation and management of CKD Am J Kidney Dis 63 2014 713 735
    • (2014) Am J Kidney Dis , vol.63 , pp. 713-735
    • Inker, L.A.1    Astor, B.C.2    Fox, C.H.3    Isakova, T.4    Lash, J.P.5    Peralta, C.A.6
  • 44
    • 23944450684 scopus 로고    scopus 로고
    • Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentration: Results of a 4-year follow-up study
    • B.A. Perkins, R.G. Nelson, B.E. Ostrander, K.L. Blouch, A.S. Krolewski, B.D. Myers, and et al. Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentration: results of a 4-year follow-up study J Am Soc Nephrol 16 2005 1404 1412
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1404-1412
    • Perkins, B.A.1    Nelson, R.G.2    Ostrander, B.E.3    Blouch, K.L.4    Krolewski, A.S.5    Myers, B.D.6
  • 45
    • 0036231457 scopus 로고    scopus 로고
    • Cystatin C is a more sensitive marker than creatinine for the estimation of GFR in type 2 diabetic patients
    • M. Mussap, M. Dalla Vestra, P. Fioretto, A. Saller, M. Varagnolo, R. Nosadini, and et al. Cystatin C is a more sensitive marker than creatinine for the estimation of GFR in type 2 diabetic patients Kidney Int 61 2002 1453 1461
    • (2002) Kidney Int , vol.61 , pp. 1453-1461
    • Mussap, M.1    Dalla Vestra, M.2    Fioretto, P.3    Saller, A.4    Varagnolo, M.5    Nosadini, R.6
  • 46
    • 0031974608 scopus 로고    scopus 로고
    • Markers of diabetic nephropathy
    • C.Y. Hong, and K.S. Chia Markers of diabetic nephropathy J Diabetes Complic 12 1998 43 60
    • (1998) J Diabetes Complic , vol.12 , pp. 43-60
    • Hong, C.Y.1    Chia, K.S.2
  • 47
    • 85047287472 scopus 로고    scopus 로고
    • Biomarkers in diabetic nephropathy: Present and future
    • G. Currie, G. McKay, and C. Delles Biomarkers in diabetic nephropathy: present and future World J Diabetes 5 2014 763 776
    • (2014) World J Diabetes , vol.5 , pp. 763-776
    • Currie, G.1    McKay, G.2    Delles, C.3
  • 48
    • 37349020357 scopus 로고    scopus 로고
    • Clinical features and management of diabetic nephropathy
    • J. Pickup, G. Williams, 3rd ed. Blackwell Science Ltd. Oxford
    • S.M. Marshall Clinical features and management of diabetic nephropathy J. Pickup, G. Williams, Text book of diabetes 3rd ed. 2003 Blackwell Science Ltd. Oxford 53.01 53.22
    • (2003) Text Book of Diabetes , pp. 5301-5322
    • Marshall, S.M.1
  • 49
    • 53749103611 scopus 로고    scopus 로고
    • Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies
    • P. Ruggenenti, P. Bettinaglio, F. Pinares, and G. Remuzzi Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies Clin J Am Soc Nephrol 3 2008 1511 1525
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 1511-1525
    • Ruggenenti, P.1    Bettinaglio, P.2    Pinares, F.3    Remuzzi, G.4
  • 50
    • 31444451581 scopus 로고    scopus 로고
    • Improved prognosis in type 1 diabetic patients with nephropathy: A prospective follow up study
    • Improved prognosis in type 1 diabetic patients with nephropathy: a prospective follow up study Kidney Int 68 2005 250 257
    • (2005) Kidney Int , vol.68 , pp. 250-257
  • 51
    • 79952186370 scopus 로고    scopus 로고
    • Oxidative stress in early diabetic nephropathy: Fueling the fire
    • D.K. Singh, P. Winocour, and K. Farrington Oxidative stress in early diabetic nephropathy: fueling the fire Nat Rev Endocrinol 7 2011 176 184
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 176-184
    • Singh, D.K.1    Winocour, P.2    Farrington, K.3
  • 53
    • 76349122683 scopus 로고    scopus 로고
    • Diabetic nephropathy: A disorder of oxygen metabolism?
    • T. Miyata, and C. Van Yparsele de Strihou Diabetic nephropathy: a disorder of oxygen metabolism? Nat Rev Nephrol 6 2010 83 95
    • (2010) Nat Rev Nephrol , vol.6 , pp. 83-95
    • Miyata, T.1    Van Yparsele De Strihou, C.2
  • 54
    • 34547788748 scopus 로고    scopus 로고
    • Suppressing renal NADPH oxidase to treat diabetic nephropathy
    • A. Tojo, K. Asaba, and M.L. Onozato Suppressing renal NADPH oxidase to treat diabetic nephropathy Expert Opin Ther Targets 11 2014 1011 1018
    • (2014) Expert Opin Ther Targets , vol.11 , pp. 1011-1018
    • Tojo, A.1    Asaba, K.2    Onozato, M.L.3
  • 55
    • 34547487924 scopus 로고    scopus 로고
    • The role of protein kinase C activation in diabetic nephropathy
    • H. Noh, and G.L. King The role of protein kinase C activation in diabetic nephropathy Kidney Int Suppl 72 2007 S49 S53
    • (2007) Kidney Int Suppl , vol.72 , pp. S49-S53
    • Noh, H.1    King, G.L.2
  • 56
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 2001 813 820
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 57
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycemic damage
    • T. Nishikawa, D. Edelstein, X.L. Du, S. Yamagishi, T. Matsumura, Y. Kaneda, and et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycemic damage Nature 404 2011 787 790
    • (2011) Nature , vol.404 , pp. 787-790
    • Nishikawa, T.1    Edelstein, D.2    Du, X.L.3    Yamagishi, S.4    Matsumura, T.5    Kaneda, Y.6
  • 58
    • 84872041647 scopus 로고    scopus 로고
    • Inflammation and the pathogenesis of diabetic nephropathy
    • J. Wada, and H. Makino Inflammation and the pathogenesis of diabetic nephropathy Clin Sci 124 2013 139 152
    • (2013) Clin Sci , vol.124 , pp. 139-152
    • Wada, J.1    Makino, H.2
  • 59
    • 82355190219 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of renal fibrosis
    • Y. Liu Cellular and molecular mechanisms of renal fibrosis Nat Rev Nephrol 2011 684 696
    • (2011) Nat Rev Nephrol , pp. 684-696
    • Liu, Y.1
  • 60
    • 80052317444 scopus 로고    scopus 로고
    • The role of TGF-β and epithelial-to-mesangial transition in diabetic nephropathy
    • C.E. Hills, and P.E. Squires The role of TGF-β and epithelial-to-mesangial transition in diabetic nephropathy Cytokine Growth Factor Rev 22 2011 131 139
    • (2011) Cytokine Growth Factor Rev , vol.22 , pp. 131-139
    • Hills, C.E.1    Squires, P.E.2
  • 61
    • 84902472921 scopus 로고    scopus 로고
    • The role of transforming growth factor-beta in diabetic nephropathy
    • G.K. Braga The role of transforming growth factor-beta in diabetic nephropathy Int J Med Genet 2014 1 6
    • (2014) Int J Med Genet , pp. 1-6
    • Braga, G.K.1
  • 62
    • 0033534573 scopus 로고    scopus 로고
    • Alternatively spliced variant of Smad 2 lacking exon 3: Comparison with wild type Smad 2 and Smad-3
    • K. Yagi, D. Goto, T. Hamamoto, S. Takenoshita, M. Kato, and K. Miyazono Alternatively spliced variant of Smad 2 lacking exon 3: comparison with wild type Smad 2 and Smad-3 J Biol Chem 274 1999 703 709
    • (1999) J Biol Chem , vol.274 , pp. 703-709
    • Yagi, K.1    Goto, D.2    Hamamoto, T.3    Takenoshita, S.4    Kato, M.5    Miyazono, K.6
  • 63
    • 9144245074 scopus 로고    scopus 로고
    • Pathogenesis of diabetic nephropathy
    • 3rd ed. J.C. Pickup, G. Williams, Blackwell Science Ltd. Oxford
    • L. Grudi, G. Gruden, and G.C. Viborti Pathogenesis of diabetic nephropathy 3rd ed. J.C. Pickup, G. Williams, Textbook of diabetes 52 2003 Blackwell Science Ltd. Oxford 1 22
    • (2003) Textbook of Diabetes , vol.52 , pp. 1-22
    • Grudi, L.1    Gruden, G.2    Viborti, G.C.3
  • 64
    • 0031916819 scopus 로고    scopus 로고
    • Proximal tubular basement membrane width in insulin-dependent diabetes mellitus
    • P.L. Brito, P. Fieoretto, K. Drummond, Y. Kim, M.W. Steffes, J.M. Basgen, and et al. Proximal tubular basement membrane width in insulin-dependent diabetes mellitus Kidney Int 53 1998 754 761
    • (1998) Kidney Int , vol.53 , pp. 754-761
    • Brito, P.L.1    Fieoretto, P.2    Drummond, K.3    Kim, Y.4    Steffes, M.W.5    Basgen, J.M.6
  • 65
    • 0024559825 scopus 로고
    • Familial clustering of diabetic kidney disease, evidence for genetic susceptibility to diabetic nephropathy
    • E.R. Seaquist, F.C. Goetz, S. Rich, and J. Barbosa Familial clustering of diabetic kidney disease, evidence for genetic susceptibility to diabetic nephropathy N Engl J Med 320 1989 1161 1165
    • (1989) N Engl J Med , vol.320 , pp. 1161-1165
    • Seaquist, E.R.1    Goetz, F.C.2    Rich, S.3    Barbosa, J.4
  • 66
    • 0002013527 scopus 로고    scopus 로고
    • Diabetic nephropathy
    • R. Jamison, R. Wilkinson, 2nd ed. Chapman and Hall London
    • R. Trevisan, J.D. Walker, and G.C. Viberti Diabetic nephropathy R. Jamison, R. Wilkinson, Nephrology 2nd ed. 1997 Chapman and Hall London 551 574
    • (1997) Nephrology , pp. 551-574
    • Trevisan, R.1    Walker, J.D.2    Viberti, G.C.3
  • 68
    • 38449087105 scopus 로고    scopus 로고
    • Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: The Family Investigation of Nephropathy and Diabetes (FIND)
    • J.R. Schelling, H.E. Abboud, S.B. Nicholas, M.V. Pahl, J.R. Sedor, S.G. Adler, and et al. Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND) Diabetes 57 2007 235 243
    • (2007) Diabetes , vol.57 , pp. 235-243
    • Schelling, J.R.1    Abboud, H.E.2    Nicholas, S.B.3    Pahl, M.V.4    Sedor, J.R.5    Adler, S.G.6
  • 69
    • 33745827044 scopus 로고    scopus 로고
    • Genetics of Kidneys in Diabetes (GoKinD) study: A genetic collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes
    • P.W. Mueller, J.J. Rogus, P.A. Cleary, Y. Zhao, A.M. Smiles, M.W. Steffes, and et al. Genetics of Kidneys in Diabetes (GoKinD) study: a genetic collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes J Am Soc Nephrol 17 2006 1782 1790
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1782-1790
    • Mueller, P.W.1    Rogus, J.J.2    Cleary, P.A.3    Zhao, Y.4    Smiles, A.M.5    Steffes, M.W.6
  • 70
    • 0030894356 scopus 로고    scopus 로고
    • Sodium-hydrogen antiporter: Its possible role in the genesis of diabetic nephropathy
    • R. Trevisan, and G. Viberti Sodium-hydrogen antiporter: its possible role in the genesis of diabetic nephropathy Nephrol Dial Transplant 12 1997 643 645
    • (1997) Nephrol Dial Transplant , vol.12 , pp. 643-645
    • Trevisan, R.1    Viberti, G.2
  • 71
    • 9144245074 scopus 로고    scopus 로고
    • Pathogenesis of diabetic nephropathy
    • 3rd ed. J.C. Pickup, G. Williams, Blackwell Science Ltd. Oxford
    • L. Gnudi, G. Gruden, and G.C. Viberti Pathogenesis of diabetic nephropathy 3rd ed. J.C. Pickup, G. Williams, Textbook of diabetes vol. 52 2003 Blackwell Science Ltd. Oxford 1 22
    • (2003) Textbook of Diabetes , vol.52 , pp. 1-22
    • Gnudi, L.1    Gruden, G.2    Viberti, G.C.3
  • 72
    • 0032840477 scopus 로고    scopus 로고
    • Screening for diabetic nephropathy: Is measurement of urinary albumin-to-creatinine ratio worthwhile?
    • T. Zelmanovitz, J. Oliveira, and M.J. de Azevedo Screening for diabetic nephropathy: is measurement of urinary albumin-to-creatinine ratio worthwhile? Diabetes Care 22 1999 1599 1600
    • (1999) Diabetes Care , vol.22 , pp. 1599-1600
    • Zelmanovitz, T.1    Oliveira, J.2    De Azevedo, M.J.3
  • 74
    • 0029076841 scopus 로고
    • Effect of intensive therapy on the development of and progression of diabetic nephropathy in the Diabetes Control and Complication Trial
    • Control And Complication Trial (dcct) Research Group D.
    • Diabetes Control and Complication Trial (DCCT) Research Group Effect of intensive therapy on the development of and progression of diabetic nephropathy in the Diabetes Control and Complication Trial Kidney Int 47 1995 1703 1720
    • (1995) Kidney Int , vol.47 , pp. 1703-1720
  • 75
    • 47649091344 scopus 로고    scopus 로고
    • Microvascular disease: What does the UKPDS tell us about diabetic nephropathy?
    • R. Bilous Microvascular disease: what does the UKPDS tell us about diabetic nephropathy? Diabet Med 25 Suppl. 2 2008 25 29
    • (2008) Diabet Med , vol.25 , pp. 25-29
    • Bilous, R.1
  • 76
    • 0142087597 scopus 로고    scopus 로고
    • Sustained effect of intensive treatment of type 1 diabetes mellitus on the development of and progression of diabetic nephropathy: The Epidemiology of Diabetes Interventions and Complications (EDIC) Study
    • Team For The Diabetes Control And Complications Trial/epidemiology Of Diabetes Interventions And Complications Research Group W.
    • Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group Sustained effect of intensive treatment of type 1 diabetes mellitus on the development of and progression of diabetic nephropathy: The Epidemiology of Diabetes Interventions and Complications (EDIC) Study JAMA 290 2003 2159 2167
    • (2003) JAMA , vol.290 , pp. 2159-2167
  • 77
    • 84855245399 scopus 로고    scopus 로고
    • Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes
    • The DCCT/EDIC Research Group Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes N Engl J Med 365 2011 2366 2376
    • (2011) N Engl J Med , vol.365 , pp. 2366-2376
    • Dcct/edic Research Group T.1
  • 78
    • 45149133036 scopus 로고    scopus 로고
    • Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    • Action In Diabetes And Vascular Disease T.And Diamicron Modified Release Controlled Evaluation (advance) Collaborative Group P.
    • The Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) Collaborative Group Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes N Engl J Med 358 2008 2560 2572
    • (2008) N Engl J Med , vol.358 , pp. 2560-2572
  • 79
    • 0032956686 scopus 로고    scopus 로고
    • Renal disease and hypertension in non-insulin dependent diabetes mellitus
    • N. Ismail, B. Becker, P. Strzelezyk, and E. Ritz Renal disease and hypertension in non-insulin dependent diabetes mellitus Kidney Int 55 1999 1 28
    • (1999) Kidney Int , vol.55 , pp. 1-28
    • Ismail, N.1    Becker, B.2    Strzelezyk, P.3    Ritz, E.4
  • 80
    • 0030404906 scopus 로고    scopus 로고
    • Renal findings in patients with short term type-2 diabetes
    • C. Keller, K. Bergis, D. Filser, and E. Ritz Renal findings in patients with short term type-2 diabetes J Am Soc Nephrol 7 1996 2627 2635
    • (1996) J Am Soc Nephrol , vol.7 , pp. 2627-2635
    • Keller, C.1    Bergis, K.2    Filser, D.3    Ritz, E.4
  • 82
    • 0019965181 scopus 로고
    • Long term antihypertensive treatment inhibiting progression of diabetic nephropathy
    • C.E. Mogensen Long term antihypertensive treatment inhibiting progression of diabetic nephropathy Br Med J 285 1982 685 688
    • (1982) Br Med J , vol.285 , pp. 685-688
    • Mogensen, C.E.1
  • 83
    • 0020549706 scopus 로고
    • Early aggression antihypertensive treatment reduces rate of decline of kidney function in diabetic nephropathy
    • H. Parving, A. Anderson, U. Smioth, and P. Svendsen early aggression antihypertensive treatment reduces rate of decline of kidney function in diabetic nephropathy Lancet 321 1983 1175 1179
    • (1983) Lancet , vol.321 , pp. 1175-1179
    • Parving, H.1    Anderson, A.2    Smioth, U.3    Svendsen, P.4
  • 84
    • 0023175729 scopus 로고
    • Effect of antihypertensive treatment on kidney function in diabetic nephropathy
    • H. Parving, A. Anderson, U. Smith, E. Hommet, E. Mathiesen, and P. Suendsen Effect of antihypertensive treatment on kidney function in diabetic nephropathy Br Med J 294 1987 1443 1447
    • (1987) Br Med J , vol.294 , pp. 1443-1447
    • Parving, H.1    Anderson, A.2    Smith, U.3    Hommet, E.4    Mathiesen, E.5    Suendsen, P.6
  • 85
    • 53749091595 scopus 로고    scopus 로고
    • Long term follow-up after tight control of blood pressure in type 2 diabetes
    • R.R. Holman, S.K. Paul, M.A. Bethel, H.A. Neil, and D.R. Mathews Long term follow-up after tight control of blood pressure in type 2 diabetes N Engl J Med 359 2008 1565 1576
    • (2008) N Engl J Med , vol.359 , pp. 1565-1576
    • Holman, R.R.1    Paul, S.K.2    Bethel, M.A.3    Neil, H.A.4    Mathews, D.R.5
  • 87
    • 34548420712 scopus 로고    scopus 로고
    • Effect of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcome in patients with type 2 diabetes mellitus (ADVANCE) trial: A randomized controlled trial
    • ADVANCE Collaborative Group Effect of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcome in patients with type 2 diabetes mellitus (ADVANCE) trial: a randomized controlled trial Lancet 370 2007 829 840
    • (2007) Lancet , vol.370 , pp. 829-840
    • Collaborative Group, A.1
  • 88
    • 67649659279 scopus 로고    scopus 로고
    • Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: Three randomized trials
    • R. Bilous, N. Chaturbedi, A.K. Sjolie, J. Fuller, R. Klein, T. Orchard, and et al. Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: three randomized trials Ann Intern Med 151 2009 11 20
    • (2009) Ann Intern Med , vol.151 , pp. 11-20
    • Bilous, R.1    Chaturbedi, N.2    Sjolie, A.K.3    Fuller, J.4    Klein, R.5    Orchard, T.6
  • 90
    • 0022113084 scopus 로고
    • Eight-month correction of hyperglycemia in insulin-dependent diabetes mellitus is associated with a significant and sustained reduction of urinary albumin excretion rates in patients with microalbuminuria
    • AUGUST
    • J.J. Bending, G.C. Viberti, R.W. Bilous, and H. Keen Eight-month correction of hyperglycemia in insulin-dependent diabetes mellitus is associated with a significant and sustained reduction of urinary albumin excretion rates in patients with microalbuminuria Diabetes 34 August (Suppl. 3) 1985 69 73
    • (1985) Diabetes , vol.34 , pp. 69-73
    • Bending, J.J.1    Viberti, G.C.2    Bilous, R.W.3    Keen, H.4
  • 91
    • 0027286787 scopus 로고
    • Meta-analysis of effects of intensive blood-glucose control on late complications of type i diabetes
    • P.H. Wang, J. Lau, and T.C. Chalmers Meta-analysis of effects of intensive blood-glucose control on late complications of type I diabetes Lancet 341 8856 1993 1306 1309
    • (1993) Lancet , vol.341 , Issue.8856 , pp. 1306-1309
    • Wang, P.H.1    Lau, J.2    Chalmers, T.C.3
  • 92
    • 0029127183 scopus 로고
    • Intensive therapy and progression to clinical albuminuria in patients with insulin dependent diabetes mellitus and microalbuminuria
    • Collaborative Study Group United Kingdom M. OCTOBER 7011
    • Microalbuminuria Collaborative Study Group, United Kingdom Intensive therapy and progression to clinical albuminuria in patients with insulin dependent diabetes mellitus and microalbuminuria BMJ 311 October (7011) 1995 973 977
    • (1995) BMJ , vol.311 , pp. 973-977
  • 93
    • 26444611430 scopus 로고    scopus 로고
    • Systematic review on urine albumin testing for early detection of diabetic complications
    • AUGUST 30 iii-vi, xiii-163
    • D.J. Newman, M.B. Mattock, A.B. Dawnay, S. Kerry, A. McGuire, M. Yaqoob, and et al. Systematic review on urine albumin testing for early detection of diabetic complications Health Technol Assess 9 August (30) 2005 iii-vi, xiii-163
    • (2005) Health Technol Assess , vol.9
    • Newman, D.J.1    Mattock, M.B.2    Dawnay, A.B.3    Kerry, S.4    McGuire, A.5    Yaqoob, M.6
  • 94
    • 0037404775 scopus 로고    scopus 로고
    • Effect of 5-year enalaprin therapy on progression of microalbuminuria and glomerular structure changes in type 1 diabetic subject
    • J. Ahmad, S. Shafiqui, S.M.A. Abidi, and I. Parvez Effect of 5-year enalaprin therapy on progression of microalbuminuria and glomerular structure changes in type 1 diabetic subject Diab Res Clin Pract 60 2003 134 138
    • (2003) Diab Res Clin Pract , vol.60 , pp. 134-138
    • Ahmad, J.1    Shafiqui, S.2    Abidi, S.M.A.3    Parvez, I.4
  • 95
    • 0035814977 scopus 로고    scopus 로고
    • Should all patients with type 1 diabetes mellitus and microalbuminuria receive angiotensin-converting enzyme inhibitors? A meta-analysis of individual patient data
    • Inhibitors In Diabetic Nephropathy Trialist Group A. MARCH 5
    • ACE Inhibitors in Diabetic Nephropathy Trialist Group Should all patients with type 1 diabetes mellitus and microalbuminuria receive angiotensin-converting enzyme inhibitors? A meta-analysis of individual patient data Ann Intern Med 134 March (5) 2001 370 379
    • (2001) Ann Intern Med , vol.134 , pp. 370-379
  • 96
    • 33645061521 scopus 로고    scopus 로고
    • Evidence for renoprotection by blockade of the renin-angiotensin-aldosterone system in hypertension and diabetes
    • APRIL 4
    • J. Karalliedde, and G. Viberti Evidence for renoprotection by blockade of the renin-angiotensin-aldosterone system in hypertension and diabetes J Hum Hypertens 20 April (4) 2006 239 253
    • (2006) J Hum Hypertens , vol.20 , pp. 239-253
    • Karalliedde, J.1    Viberti, G.2
  • 97
    • 0030770447 scopus 로고    scopus 로고
    • Effective postponement of diabetic nephropathy with enalapril in normotensive type 2 diabetic patients with microalbuminuria
    • OCTOBER 10
    • J. Ahmad, M.A. Siddiqui, and H. Ahmad Effective postponement of diabetic nephropathy with enalapril in normotensive type 2 diabetic patients with microalbuminuria Diabetes Care 20 October (10) 1997 1576 1581
    • (1997) Diabetes Care , vol.20 , pp. 1576-1581
    • Ahmad, J.1    Siddiqui, M.A.2    Ahmad, H.3
  • 98
    • 9044252719 scopus 로고    scopus 로고
    • Effects of long-term enalapril treatment on persistent microalbuminuria in normotensive type 2 diabetic patients: Results of a 4-year, prospective, randomized study
    • FEBRUARY 2
    • T. Sano, N. Hotta, T. Kawamura, H. Matsumae, S. Chaya, H. Sasaki, and et al. Effects of long-term enalapril treatment on persistent microalbuminuria in normotensive type 2 diabetic patients: results of a 4-year, prospective, randomized study Diabet Med 13 February (2) 1996 120 124
    • (1996) Diabet Med , vol.13 , pp. 120-124
    • Sano, T.1    Hotta, N.2    Kawamura, T.3    Matsumae, H.4    Chaya, S.5    Sasaki, H.6
  • 99
    • 0033055724 scopus 로고    scopus 로고
    • Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: The Steno type 2 randomised study
    • FEBRUARY 9153
    • P. Gaede, P. Vedel, H.H. Parving, and O. Pedersen Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: the Steno type 2 randomised study Lancet 353 February (9153) 1999 617 622
    • (1999) Lancet , vol.353 , pp. 617-622
    • Gaede, P.1    Vedel, P.2    Parving, H.H.3    Pedersen, O.4
  • 100
    • 8344260643 scopus 로고    scopus 로고
    • Remission to normoalbuminuria during multifactorial treatment preserves kidney function in patients with type 2 diabetes and microalbuminuria
    • NOVEMBER 11
    • P. Gaede, L. Tarnow, P. Vedel, H.H. Parving, and O. Pedersen Remission to normoalbuminuria during multifactorial treatment preserves kidney function in patients with type 2 diabetes and microalbuminuria Nephrol Dial Transplant 19 November (11) 2004 2784 2788
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 2784-2788
    • Gaede, P.1    Tarnow, L.2    Vedel, P.3    Parving, H.H.4    Pedersen, O.5
  • 101
    • 38949210220 scopus 로고    scopus 로고
    • Effect of a multifactorial intervention on mortality in type 2 diabetes
    • FEBRUARY 6
    • P. Gaede, H. Lund-Andersen, H.H. Parving, and O. Pedersen Effect of a multifactorial intervention on mortality in type 2 diabetes N Engl J Med 358 February (6) 2008 580 591
    • (2008) N Engl J Med , vol.358 , pp. 580-591
    • Gaede, P.1    Lund-Andersen, H.2    Parving, H.H.3    Pedersen, O.4
  • 102
    • 0022590261 scopus 로고
    • Intermittent clinical proteinuria and renal function in diabetes: Evolution and the effect of glycaemic control
    • JANUARY 6513
    • J.J. Bending, G.C. Viberti, P.J. Watkins, and H. Keen Intermittent clinical proteinuria and renal function in diabetes: evolution and the effect of glycaemic control Br Med J (Clin Res Ed) 292 January (6513) 1986 83 86
    • (1986) Br Med J (Clin Res Ed) , vol.292 , pp. 83-86
    • Bending, J.J.1    Viberti, G.C.2    Watkins, P.J.3    Keen, H.4
  • 103
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group
    • NOVEMBER 20
    • E.J. Lewis, L.G. Hunsicker, R.P. Bain, and R.D. Rohde The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group N Engl J Med 329 November (20) 1993 1456 1462
    • (1993) N Engl J Med , vol.329 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3    Rohde, R.D.4
  • 104
    • 44849114597 scopus 로고    scopus 로고
    • Aliskiren combined with losartan in type 2 diabetes and nephropathy
    • JUNE 23, Study Investigators A.
    • H.H. Parving, F. Persson, J.B. Lewis, E.J. Lewis, N.K. Hollenberg, and AVOID Study Investigators Aliskiren combined with losartan in type 2 diabetes and nephropathy N Engl J Med 358 June (23) 2008 2433 2446
    • (2008) N Engl J Med , vol.358 , pp. 2433-2446
    • Parving, H.H.1    Persson, F.2    Lewis, J.B.3    Lewis, E.J.4    Hollenberg, N.K.5
  • 105
    • 49149087718 scopus 로고    scopus 로고
    • Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial
    • AUGUST 9638
    • J.F. Mann, R.E. Schmieder, M. McQueen, L. Dyal, H. Schumacher, J. Pogue, and et al. Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial Lancet 372 August (9638) 2008 547 553
    • (2008) Lancet , vol.372 , pp. 547-553
    • Mann, J.F.1    Schmieder, R.E.2    McQueen, M.3    Dyal, L.4    Schumacher, H.5    Pogue, J.6
  • 106
    • 48749096999 scopus 로고    scopus 로고
    • Institute For Clinical Excellence (nice) N. Clinical Guidelines (G66). Available from: (accessed June 2010)
    • National Institute for Clinical Excellence (NICE) Type 2 diabetes: the management of type 2 diabetes 2008 Clinical Guidelines (G66). Available from: http://guidance.nice.org.uk/G66 (accessed June 2010)
    • (2008) Type 2 Diabetes: The Management of Type 2 Diabetes
  • 107
    • 33845996154 scopus 로고    scopus 로고
    • Standards of medical care in diabetes - 2007
    • JANUARY
    • American Diabetes Association Standards of medical care in diabetes - 2007 Diabetes Care 30 January (Suppl. 1) 2007 S4 S41
    • (2007) Diabetes Care , vol.30 , pp. S4-S41
    • Diabetes Association A.1
  • 108
    • 33846262603 scopus 로고    scopus 로고
    • Fenofibrate: A review of its use in primary dyslipidaemia, the metabolic syndrome and type 2 diabetes mellitus
    • G.M. Keating, and K.F. Croom Fenofibrate: a review of its use in primary dyslipidaemia, the metabolic syndrome and type 2 diabetes mellitus Drugs 67 2007 121 153
    • (2007) Drugs , vol.67 , pp. 121-153
    • Keating, G.M.1    Croom, K.F.2
  • 109
    • 0035166933 scopus 로고    scopus 로고
    • Effect of lipid reduction on the progression of renal disease: A meta-analysis
    • L.F. Fried, T.J. Orchard, and B.L. Kasiske Effect of lipid reduction on the progression of renal disease: a meta-analysis Kidney Int 59 2001 260 269
    • (2001) Kidney Int , vol.59 , pp. 260-269
    • Fried, L.F.1    Orchard, T.J.2    Kasiske, B.L.3
  • 110
    • 0037840242 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 5963 people with diabetes: A randomised placebo-controlled trial
    • The Heart Protection Study MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial Lancet 361 2003 2005 2016
    • (2003) Lancet , vol.361 , pp. 2005-2016
    • Heart Protection Study, T.1
  • 111
    • 33645288571 scopus 로고    scopus 로고
    • Effect of rosuvastatin or atorvastatin on urinary albumin excretion and renal function in type 2 diabetic patients
    • Study Investigators U.
    • J. Sorof, C. Berne, A. Siewert-Delle, L. Jørgensen, P. Sager, and URANUS Study Investigators Effect of rosuvastatin or atorvastatin on urinary albumin excretion and renal function in type 2 diabetic patients Diabetes Res Clin Pract 72 2006 81 87
    • (2006) Diabetes Res Clin Pract , vol.72 , pp. 81-87
    • Sorof, J.1    Berne, C.2    Siewert-Delle, A.3    Jørgensen, L.4    Sager, P.5
  • 112
    • 0035700258 scopus 로고    scopus 로고
    • Effect of cerivastatin on urinary albumin excretion and plasma endothelin-1 concentrations in type 2 diabetes patients with microalbuminuria and dyslipidemia
    • T. Nakamura, C. Ushiyama, K. Hirokawa, S. Osada, N. Shimada, and H. Koide Effect of cerivastatin on urinary albumin excretion and plasma endothelin-1 concentrations in type 2 diabetes patients with microalbuminuria and dyslipidemia Am J Nephrol 21 2001 449 454
    • (2001) Am J Nephrol , vol.21 , pp. 449-454
    • Nakamura, T.1    Ushiyama, C.2    Hirokawa, K.3    Osada, S.4    Shimada, N.5    Koide, H.6
  • 113
    • 14844292088 scopus 로고    scopus 로고
    • Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: Results from the Diabetes Atherosclerosis Intervention Study (DAIS)
    • Investigators D.
    • J.C. Ansquer, C. Foucher, S. Rattier, M.R. Taskinen, G. Steiner, and DAIS Investigators Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: results from the Diabetes Atherosclerosis Intervention Study (DAIS) Am J Kidney Dis 45 2005 485 493
    • (2005) Am J Kidney Dis , vol.45 , pp. 485-493
    • Ansquer, J.C.1    Foucher, C.2    Rattier, S.3    Taskinen, M.R.4    Steiner, G.5
  • 114
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): Randomised controlled trial
    • A. Keech, R.J. Simes, P. Barter, J. Best, R. Scott, M.R. Taskinen, and et al. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial Lancet 366 2005 1849 1861
    • (2005) Lancet , vol.366 , pp. 1849-1861
    • Keech, A.1    Simes, R.J.2    Barter, P.3    Best, J.4    Scott, R.5    Taskinen, M.R.6
  • 115
    • 29944441641 scopus 로고    scopus 로고
    • Field, a randomized clinical trial of cardiovascular prevention with fenofibrate in type 2 diabetes
    • R.P. Radermecker, and A.J. Scheen Field, a randomized clinical trial of cardiovascular prevention with fenofibrate in type 2 diabetes Rev Med Liege 60 2005 957 961
    • (2005) Rev Med Liege , vol.60 , pp. 957-961
    • Radermecker, R.P.1    Scheen, A.J.2
  • 118
    • 2542450403 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid consumption may play a role in the onset and regression of microalbuminuria in well-controlled type 1 and type 2 diabetic people: A 7-year, prospective, population-based, observational multicenter study
    • Nutrition Study Group Spanish Diabetes Association D.
    • C. Cárdenas, E. Bordiu, J. Bagazgoitia, A.L. Calle-Pascual, and Diabetes Nutrition Study Group, Spanish Diabetes Association Polyunsaturated fatty acid consumption may play a role in the onset and regression of microalbuminuria in well-controlled type 1 and type 2 diabetic people: a 7-year, prospective, population-based, observational multicenter study Diabetes Care 27 2004 1454 1457
    • (2004) Diabetes Care , vol.27 , pp. 1454-1457
    • Cárdenas, C.1    Bordiu, E.2    Bagazgoitia, J.3    Calle-Pascual, A.L.4
  • 120
    • 26044472651 scopus 로고    scopus 로고
    • A randomized trial of low-protein diet in type 1 and in type 2 diabetes mellitus patients with incipient and overt nephropathy
    • B. Dussol, C. Iovanna, D. Raccah, P. Darmon, S. Morange, P. Vague, and et al. A randomized trial of low-protein diet in type 1 and in type 2 diabetes mellitus patients with incipient and overt nephropathy J Ren Nutr 15 2005 398 406
    • (2005) J Ren Nutr , vol.15 , pp. 398-406
    • Dussol, B.1    Iovanna, C.2    Raccah, D.3    Darmon, P.4    Morange, S.5    Vague, P.6
  • 121
    • 15444360456 scopus 로고    scopus 로고
    • Risk factors for mortality in type II (non-insulin-dependent) diabetes: Evidence of a role for neuropathy and a protective effect of HLA-DR4
    • C.M. Forsblom, T. Sane, P.H. Groop, K.J. Tötterman, M. Kallio, C. Saloranta, and et al. Risk factors for mortality in type II (non-insulin-dependent) diabetes: evidence of a role for neuropathy and a protective effect of HLA-DR4 Diabetologia 41 1998 1253 1262
    • (1998) Diabetologia , vol.41 , pp. 1253-1262
    • Forsblom, C.M.1    Sane, T.2    Groop, P.H.3    Tötterman, K.J.4    Kallio, M.5    Saloranta, C.6
  • 122
    • 13844275224 scopus 로고    scopus 로고
    • Microalbuminuria and risk factors in type 1 and type 2 diabetic patients
    • Committee Of The Swedish National Diabetes Register S.
    • J. Cederholm, B. Eliasson, P.M. Nilsson, L. Weiss, S. Gudbjörnsdottir, and Steering Committee of the Swedish National Diabetes Register Microalbuminuria and risk factors in type 1 and type 2 diabetic patients Diabetes Res Clin Pract 67 2005 258 266
    • (2005) Diabetes Res Clin Pract , vol.67 , pp. 258-266
    • Cederholm, J.1    Eliasson, B.2    Nilsson, P.M.3    Weiss, L.4    Gudbjörnsdottir, S.5
  • 123
    • 0035689881 scopus 로고    scopus 로고
    • Cigarette smoking is a risk factor for nephropathy and its progression in type 2 diabetes mellitus
    • G. Gambaro, G. Bax, M. Fusaro, M. Normanno, S.M. Manani, M. Zanella, and et al. Cigarette smoking is a risk factor for nephropathy and its progression in type 2 diabetes mellitus Diabetes Nutr Metab Clin Exp 14 2001 337 342
    • (2001) Diabetes Nutr Metab Clin Exp , vol.14 , pp. 337-342
    • Gambaro, G.1    Bax, G.2    Fusaro, M.3    Normanno, M.4    Manani, S.M.5    Zanella, M.6
  • 124
    • 33746520563 scopus 로고    scopus 로고
    • Combined AGE inhibition and ACEi decreases the progression of established diabetic nephropathy in B6 db/db mice
    • F. Zheng, Y.J. Zeng, A.R. Plati, S.J. Elliot, M. Berho, M. Potier, and et al. Combined AGE inhibition and ACEi decreases the progression of established diabetic nephropathy in B6 db/db mice Kidney Int 70 2006 507 514
    • (2006) Kidney Int , vol.70 , pp. 507-514
    • Zheng, F.1    Zeng, Y.J.2    Plati, A.R.3    Elliot, S.J.4    Berho, M.5    Potier, M.6
  • 125
    • 35548975242 scopus 로고    scopus 로고
    • Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy
    • M. Williams, W. Bolton, R. Khalifah, T. Degenhardt, R. Schotzinger, and J. McGill Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy Am J Nephrol 27 2007 605 614
    • (2007) Am J Nephrol , vol.27 , pp. 605-614
    • Williams, M.1    Bolton, W.2    Khalifah, R.3    Degenhardt, T.4    Schotzinger, R.5    McGill, J.6
  • 130
    • 0036014944 scopus 로고    scopus 로고
    • Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: The DINAS Randomized Trial
    • G. Gambaro, I. Kinalska, A. Oksa, P. Pont'uch, M. Hertlová, J. Olsovsky, and et al. Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: The DINAS Randomized Trial J Am Soc Nephrol 13 2002 1615 1625
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1615-1625
    • Gambaro, G.1    Kinalska, I.2    Oksa, A.3    Pont'Uch, P.4    Hertlová, M.5    Olsovsky, J.6
  • 131
    • 84863393468 scopus 로고    scopus 로고
    • Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy
    • D.K. Packham, R. Wolfe, A.T. Reutens, T. Berl, H.L. Heerspink, R. Rohde, and et al. Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy J Am Soc Nephrol 23 2012 123 130
    • (2012) J Am Soc Nephrol , vol.23 , pp. 123-130
    • Packham, D.K.1    Wolfe, R.2    Reutens, A.T.3    Berl, T.4    Heerspink, H.L.5    Rohde, R.6
  • 132
    • 79960563100 scopus 로고    scopus 로고
    • Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation
    • M.S. Farvid, F. Homayouni, Z. Amiri, and F. Adelmanesh Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation Diabetes Res Clin Pract 93 2011 86 94
    • (2011) Diabetes Res Clin Pract , vol.93 , pp. 86-94
    • Farvid, M.S.1    Homayouni, F.2    Amiri, Z.3    Adelmanesh, F.4
  • 133
    • 25644452089 scopus 로고    scopus 로고
    • Comparison of the effects of vitamins and/or mineral supplementation on glomerular and tubular dysfunction in type 2 diabetes
    • M.S. Farvid, M. Jalali, F. Siassi, and M. Hosseini Comparison of the effects of vitamins and/or mineral supplementation on glomerular and tubular dysfunction in type 2 diabetes Diabetes Care 28 2005 2458 2464
    • (2005) Diabetes Care , vol.28 , pp. 2458-2464
    • Farvid, M.S.1    Jalali, M.2    Siassi, F.3    Hosseini, M.4
  • 134
    • 79952998056 scopus 로고    scopus 로고
    • Antioxidants in the treatment of diabetes
    • S. Golbidi Antioxidants in the treatment of diabetes Curr Diabetes Rev 7 2011 106 125
    • (2011) Curr Diabetes Rev , vol.7 , pp. 106-125
    • Golbidi, S.1
  • 135
    • 0042867413 scopus 로고    scopus 로고
    • Contribution of polyol pathway to diabetes-induced oxidative stress
    • S.S.M. Chung Contribution of polyol pathway to diabetes-induced oxidative stress J Am Soc Nephrol 14 2003 233 236
    • (2003) J Am Soc Nephrol , vol.14 , pp. 233-236
    • Chung, S.S.M.1
  • 136
    • 26444477394 scopus 로고    scopus 로고
    • A novel series of non-carboxylic acid, non-hydantoin inhibitors of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran-2-sulfonyl)-2H-pyridazin-3-one and congeners
    • B.L. Mylari, S.J. Armento, D.A. Beebe, E.L. Conn, J.B. Coutcher, M.S. Dina, and et al. A novel series of non-carboxylic acid, non-hydantoin inhibitors of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran-2-sulfonyl)-2H-pyridazin-3-one and congeners J Med Chem 48 2005 6326 6339
    • (2005) J Med Chem , vol.48 , pp. 6326-6339
    • Mylari, B.L.1    Armento, S.J.2    Beebe, D.A.3    Conn, E.L.4    Coutcher, J.B.5    Dina, M.S.6
  • 137
    • 0015061764 scopus 로고
    • Activators and inhibitors of lens aldose reductase
    • J. Jedziniak, and J. Kinoshita Activators and inhibitors of lens aldose reductase Invest Ophthalmol Vis Sci 10 1971 357 366
    • (1971) Invest Ophthalmol Vis Sci , vol.10 , pp. 357-366
    • Jedziniak, J.1    Kinoshita, J.2
  • 138
    • 0015887637 scopus 로고
    • Polyol accumulation in galactosemic and diabetic rats: Control by an aldose reductase inhibitor
    • E. Dvornik, N. Simard-Duquesne, M. Krami, K. Sestanj, K.H. Gabbay, J.H. Kinoshita, and et al. Polyol accumulation in galactosemic and diabetic rats: control by an aldose reductase inhibitor Science 182 1973 1146 1148
    • (1973) Science , vol.182 , pp. 1146-1148
    • Dvornik, E.1    Simard-Duquesne, N.2    Krami, M.3    Sestanj, K.4    Gabbay, K.H.5    Kinoshita, J.H.6
  • 139
    • 42949097094 scopus 로고    scopus 로고
    • Epalrestat: An aldose reductase inhibitor for the treatment of diabetic neuropathy
    • M.A. Ramirez, and N.L. Borja Epalrestat: an aldose reductase inhibitor for the treatment of diabetic neuropathy Pharmacother: J Hum Pharmacol Drug Ther 28 2008 646 655
    • (2008) Pharmacother: J Hum Pharmacol Drug Ther , vol.28 , pp. 646-655
    • Ramirez, M.A.1    Borja, N.L.2
  • 141
    • 78649913769 scopus 로고    scopus 로고
    • Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: Implications in type 2 diabetic nephropathy
    • M. Sedeek, G. Callera, A. Montezano, A. Gutsol, F. Heitz, C. Szyndralewiez, and et al. Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy Am J Physiol Renal 299 2010 F1348 F1358
    • (2010) Am J Physiol Renal , vol.299 , pp. F1348-F1358
    • Sedeek, M.1    Callera, G.2    Montezano, A.3    Gutsol, A.4    Heitz, F.5    Szyndralewiez, C.6
  • 143
    • 79954582442 scopus 로고    scopus 로고
    • Effect of bardoxolone methyl on kidney function in patients with T2D and stage 3b-4 CKD
    • P.E. Pergola, M. Krauth, J.W. Huff, D.A. Ferguson, S. Ruiz, C.J. Meyer, and et al. Effect of bardoxolone methyl on kidney function in patients with T2D and stage 3b-4 CKD Am J Nephrol 33 2011 469 476
    • (2011) Am J Nephrol , vol.33 , pp. 469-476
    • Pergola, P.E.1    Krauth, M.2    Huff, J.W.3    Ferguson, D.A.4    Ruiz, S.5    Meyer, C.J.6
  • 144
    • 84869239084 scopus 로고    scopus 로고
    • A novel CC chemokine receptor 2 antagonist prevents progression of albuminuria and atherosclerosis in mouse models
    • M. Okamoto, M. Fuchigami, T. Suzuki, and N. Watanabe A novel CC chemokine receptor 2 antagonist prevents progression of albuminuria and atherosclerosis in mouse models Biol Pharm Bull 35 2011 2069 2074
    • (2011) Biol Pharm Bull , vol.35 , pp. 2069-2074
    • Okamoto, M.1    Fuchigami, M.2    Suzuki, T.3    Watanabe, N.4
  • 145
    • 40049099699 scopus 로고    scopus 로고
    • Oral administration of GW788388, an inhibitor of TGF-beta type i and II receptor kinases, decreases renal fibrosis
    • 110
    • M. Petersen, M. Thorikay, M. Deckers, M. van Dinther, E.T. Grygielko, F. Gellibert, and et al. Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis Kidney Int 73 2008 705 715 110
    • (2008) Kidney Int , vol.73 , pp. 705-715
    • Petersen, M.1    Thorikay, M.2    Deckers, M.3    Van Dinther, M.4    Grygielko, E.T.5    Gellibert, F.6
  • 147
    • 37549046405 scopus 로고    scopus 로고
    • Renoprotective role of the Vitamin D receptor in diabetic nephropathy
    • Z. Zhang, L. Sun, Y. Wang, G. Ning, A.W. Minto, J. Kong, and et al. Renoprotective role of the vitamin D receptor in diabetic nephropathy Kidney Int 73 2008 163 171
    • (2008) Kidney Int , vol.73 , pp. 163-171
    • Zhang, Z.1    Sun, L.2    Wang, Y.3    Ning, G.4    Minto, A.W.5    Kong, J.6
  • 148
    • 79952742829 scopus 로고    scopus 로고
    • Podocytes as target of Vitamin D
    • Y. Li Podocytes as target of vitamin D Curr Diabetes Rev 7 2011 35 40
    • (2011) Curr Diabetes Rev , vol.7 , pp. 35-40
    • Li, Y.1
  • 149
    • 67651100831 scopus 로고    scopus 로고
    • Transplantation in type 1 diabetes
    • JULY 7
    • C. Morath, and M. Zeier Transplantation in type 1 diabetes Nephrol Dial Transplant 24 July (7) 2009 2026 2029
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2026-2029
    • Morath, C.1    Zeier, M.2
  • 150
    • 1042268052 scopus 로고    scopus 로고
    • Pancreas transplantation in type 1 diabetes
    • JANUARY, Diabetes Association A.
    • P. Robertson, C. Davis, J. Larsen, R. Stratta, D.E. Sutherland, and American Diabetes Association Pancreas transplantation in type 1 diabetes Diabetes Care 27 January (Suppl. 1) 2004 S105
    • (2004) Diabetes Care , vol.27 , pp. S105
    • Robertson, P.1    Davis, C.2    Larsen, J.3    Stratta, R.4    Sutherland, D.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.