In patients with type 1 diabetes and new-onset microalbuminuria the development of advanced chronic kidney disease may not require progression to proteinuria

Kidney International

Volumn 77, Issue 1, 2010, Pages 57-64

  Perkins, Bruce A ^a   Ficociello, Linda H ^b   Roshan, Bijan ^b   Warram, James H ^b   Krolewski, Andrzej S ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b JOSLIN DIABETES CENTER   (United States)

Author keywords

Angiotensin; Chronic kidney disease; Glomerular filtration rate; Microalbuminuria; Renal function decline

Indexed keywords

ALBUMIN; ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ADULT; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DIABETIC PATIENT; DISEASE COURSE; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEINURIA; URINARY EXCRETION;

AGED; AGED, 80 AND OVER; ALBUMINURIA; CHRONIC DISEASE; COHORT STUDIES; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; FEMALE; HUMANS; KIDNEY DISEASES; MALE; MIDDLE AGED; PROTEINURIA;

EID: 72949106696     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2009.399     Document Type: Article

References (44)

1. Viberti GC, Hill RD, Jarrett RJ et al. Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus. Lancet 1982; 1: 1430-1432.
2. Parving HH, Oxenboll B, Svendsen PA et al. Early detection of patients at risk of developing diabetic nephropathy: A longitudinal study of urinary albumin excretion. Acta Endocrinol (Copenh) 1982; 100: 550-555.
3. Mogensen CE, Christensen CK. Predicting diabetic nephropathy in insulin-dependent patients. N Engl J Med 1984; 311: 89-93.
4. Williams ME. Diabetic nephropathy: the proteinuria hypothesis. Am J Nephrol 2005; 25: 77-94.
5. ACE Inhibitors in Diabetic Nephropathy Trialist Group. Should all patients with type 1 diabetes mellitus and microalbuminuria receive angiotensin-converting enzyme inhibitors? A meta-analysis of individual patient data. Ann Intern Med 2001; 134: 370-379.
6. American Diabetes Association Clinical Practice Guidelines. Nephropathy in Diabetes. Diabetes Care 2004; 27: S79-S83.
7. Perkins BA, Ficociello LH, Silva KH et al. Regression of microalbuminuria in type 1 diabetes. N Engl J Med 2003; 348: 2285-2293.
8. Giorgino F, Laviola L, Cavallo Perin P et al. Factors associated with progression to macroalbuminuria in microalbuminuric Type 1 diabetic patients: the EURODIAB Prospective Complications Study. Diabetologia 2004; 47: 1020-1028.
9. Ficociello LH, Perkins BA, Silva KH et al. Determinants of progression from microalbuminuria to proteinuria in patients who have type 1 diabetes and are treated with angiotensin-converting enzyme inhibitors. Clin J Am Soc Nephrol 2007; 2: 461-469.
10. Hovind P, Tarnow L, Rossing P et al. Predictors for the development of microalbuminuria and macroalbuminuria in patients with type 1 diabetes: inception cohort study. BMJ 2004; 328: 1105.
11. Amin R, Widmer B, Prevost AT et al. Risk of microalbuminuria and progression to macroalbuminuria in a cohort with childhood onset type 1 diabetes: prospective observational study. BMJ 2008; 336: 697-701.
12. Perkins BA, Ficociello LH, Ostrander BE et al. Microalbuminuria and the risk of early progressive renal function decline in type 1 diabetes. J Am Soc Nephrol 2007; 18: 1353-1361.
13. Scott LJ, Warram JH, Hanna LS et al. A nonlinear effect of hyperglycemia and current cigarette smoking are major determinants of the onset of microalbuminuria in type 1 diabetes. Diabetes 2001; 50: 2842-2849.
14. Lindeman RD, Tobin J, Shock NW. Longitudinal studies on the rate of decline in renal function with age. J Am Geriatr Soc 1985; 33: 278-285.
15. Tsalamandris C, Allen TJ, Gilbert RE et al. Progressive decline in renal function function in diabetic patients with and without albuminuria. Diabetes 1994; 43: 649-655.
16. Lane PH, Steffes MW, Mauer SM. Glomerular structure in IDDM women with low glomerular filtration rate and normal urinary albumin excretion. Diabetes 1992; 41: 581-586.
17. Caramori ML, Fioretto P, Mauer M. Low glomerular filtration rate in normoalbuminuric type 1 diabetic patients: an indicator of more advanced glomerular lesions. Diabetes 2003; 52: 1036-1040.
18. Viberti GC, Bilous RW, Mackintosh D et al. Monitoring glomerular function in diabetic nephropathy: a prospective study. Am J Med 1983; 74: 256-264.
19. Zeller K, Whittaker E, Sullivan L et al. Effect of restricting dietary protein on the progression of renal failure in patients with insulin-dependent diabetes mellitus. N Engl J Med 1991; 324: 78-84.
20. Biesenbach G, Janko O, Zazgornik J. Similar rate of progression in the predialysis phase in type I and type II diabetes mellitus. Nephrol Dial Transplant 1994; 9: 1097-1102.
21. Mathiesen ER, Feldt-Rasmussen B, Hommel E et al. Stable glomerular filtration rate in normotensive IDDM patients with stable microalbuminuria. A 5-year prospective study. Diabetes Care 1997; 20: 286-289.
22. Hovind P, Rossing P, Tarnow L et al. Progression of diabetic nephropathy. Kidney Int 2001; 59: 702-709.
23. Costacou T, Ellis D, Fried L et al. Sequence of progression of albuminuria and decreased GFR in persons with type 1 diabetes: a cohort study. Am J Kidney Dis 2007; 50: 721-732.
24. Feldt-Rasmussen B, Mathiesen ER, Jensen T et al. Effect of improved metabolic control on loss of kidney function in type 1 (insulin-dependent) diabetic patients: an update of the Steno studies. Diabetologia 1991; 34: 164-170.
25. Rudberg S, Osterby R. Decreasing glomerular filtration rate-an indicator of more advanced diabetic glomerulopathy in the early course of microalbuminuria in IDDM adolescents? Nephrol Dial Transplant 1997; 12: 1149-1154.
26. Dahlquist G, Stattin EL, Rudberg S. Urinary albumin excretion rate and glomerular filtration rate in the prediction of diabetic nephropathy; a long-term follow-up study of childhood onset type-1 diabetic patients. Nephrol Dial Transplant 2001; 16: 1382-1386.
27. Bangstad HJ, Osterby R, Rudberg S et al. Kidney function and glomerulopathy over 8 years in young patients with type I (insulin-dependent) diabetes mellitus and microalbuminuria. Diabetologia 2002; 45: 253-261.
28. Amin R, Turner C, van Aken S et al. The relationship between microalbuminuria and glomerular filtration rate in young type 1 diabetic subjects: The Oxford Regional Prospective Study. Kidney Int 2005; 68: 1740-1749.
29. Premaratne E, MacIsaac RJ, Finch S et al. Serial measurements of cystatin C are more accurate than creatinine-based methods in detecting declining renal function in type 1 diabetes. Diabetes Care 2008; 31: 971-973.
30. Tan GD, Lewis AV, James TJ et al. Clinical usefulness of cystatin C for the estimation of glomerular filtration rate in type 1 diabetes: reproducibility and accuracy compared with standard measures and iohexol clearance. Diabetes Care 2002; 25: 2004-2009.
31. Perkins BA, Nelson RG, Ostrander BE et al. Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentration: results of a 4-year follow-up study. J Am Soc Nephrol 2005; 16: 404-412.
32. Perkins BA, Nelson RG, Krolewski AS. Cystatin C and the risk of death. N Engl J Med 2005; 353: 842-844.
33. Mauer M. The Renin Angiotensin System Study (RASS): effects of enalapril and losartan on diabetic renal and retinal lesions in normotensive, normoalbuminuric type I diabetic patients. Invited lecture presented in "Late-Breaking Interventions in Glomerular Disease and Diabetic Nephropathy", American Society of Nephrology Renal Week 2007.
34. Mann JF, Schmieder RE, McQueen M, et al., for the ONTARGET investigators. Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multi-centre, andomized, double-blind, controlled trial. Lancet 2008; 16: 547-553.
35. Jerums G, Panagiotopoulos S, Premaratne E et al. Lowering of proteinuria in response to antihypertensive therapy predicts improved renal function in late but not in early diabetic nephropathy: a pooled analysis. Am J Nephrol 2008; 28: 614-627.
36. Steinke JM, Sinaiko AR, Kramer MS et al. International Diabetic Nephopathy Study Group. The early natural history of nephropathy in type 1 Diabetes: III. Predictors of 5-year urinary albumin excretion rate patterns in initially normoalbuminuric patients. Diabetes 2005; 54: 2164-2171.
37. Perkins BA, Krolewski AS. Early nephropathy in type 1 diabetes: the importance of early renal function decline. Curr Opin Nephrol Hypertens 2009; 18: 233-240.
38. Krolewski AS, Laffel LMB, Krolewski M et al. Glycosylated hemoglobin and the risk of microalbuminuria in patients with insulin-dependent diabetes mellitus. N Engl J Med 1995; 332: 1251-1255.
39. Warram JH, Scott LJ, Hanna LS et al. Progression of microalbuminuria to proteinuria in type 1 diabetes: nonlinear relationship with hyperglycemia. Diabetes 2000; 49: 94-100.
40. Levey AS, Greene T, Kusek JW et al. A simplified equation to predict glomerular filtration rate from serum creatinine. J Am Soc Nephrol 2000; 11: A0828.
41. National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 2002; 39: S1-S266.
42. Levey AS, Coresh J, Greene T et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med 2006; 145: 247-254.
43. Rule AD, Larson TS, Bergstralh EJ et al. Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. Ann Intern Med 2004; 141: 929-937.
44. Macisaac RJ, Tsalamandris C, Thomas MC et al. Estimating glomerular filtration rate in diabetes: a comparison of cystatin-C-and creatinine-based methods. Diabetologia 2006; 49: 1686-1689.