Potent degradation of neuronal miRNAs induced by highly complementary targets

EMBO Reports

Volumn 16, Issue 4, 2015, Pages 500-511

  De La Mata, Manuel ^a   Gaidatzis, Dimos ^a,b   Vitanescu, Mirela ^a,e   Stadler, Michael B ^a,b,c   Wentzel, Corinna ^d,f   Scheiffele, Peter ^d   Filipowicz, Witold ^a,c   Großhans, Helge ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d UNIVERSITY OF BASEL   (Switzerland)

^e UNIVERSITY OF BERN   (Switzerland)

^f UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

cooperativity; miRNA target; miRNA turnover; non templated RNA 3 end nucleotide additions; primary hippocampal neurons

Indexed keywords

ARGONAUTE 2 PROTEIN; ARGONAUTE PROTEIN; MESSENGER RNA; MICRORNA; EIF2C2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CORRELATIONAL STUDY; GENE SILENCING; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN TARGETING; RAT; RNA SEQUENCE; TARGET RNA DIRECTED MIRNA DEGRADATION; ANIMAL; BASE PAIRING; CEREBELLUM; CYTOLOGY; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; HIPPOCAMPUS; LENTIVIRINAE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PRIMARY CELL CULTURE; RNA STABILITY; SIGNAL TRANSDUCTION;

RODENTIA;

ANIMALS; ARGONAUTE PROTEINS; BASE PAIRING; BASE SEQUENCE; CEREBELLUM; GENE EXPRESSION REGULATION; GENETIC VECTORS; HIPPOCAMPUS; LENTIVIRUS; MICE; MICRORNAS; MOLECULAR SEQUENCE DATA; NEURONS; PRIMARY CELL CULTURE; RATS; RNA STABILITY; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84926168083     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201540078     Document Type: Article

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