The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes

PLoS Genetics

Volumn 11, Issue 3, 2015, Pages

  Pacheco, Sarai ^a   Marcet Ortega, Marina ^a   Lange, Julian ^b   Jasin, Maria ^b   Keeney, Scott ^b   Roig, Ignasi ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ATM PROTEIN; CHECKPOINT KINASE 2; HISTONE H1; HISTONE H1T; MRE11 PROTEIN; NIBRIN; RAD50 PROTEIN; TRIP13 PROTEIN; UNCLASSIFIED DRUG; ATM PROTEIN, MOUSE; CELL CYCLE PROTEIN; CHEK2 PROTEIN, MOUSE; DNA BINDING PROTEIN; DNA LIGASE; MRE11A PROTEIN, MOUSE; NIJMEGEN BREAKAGE SYNDROME 1 PROTEIN, MOUSE; NUCLEAR PROTEIN; PACHYTENE CHECKPOINT 2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; EPISTASIS; GENE MUTATION; MALE; MEIOTIC RECOMBINATION; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PACHYTENE; RECOMBINATION DEPENDENT PACHYTENE ARREST; SEMINIFEROUS TUBULE; SEX BODY FORMATION; SPERMATOCYTE; SPERMATOGENESIS; TESTIS SIZE; ANIMAL; CELL CYCLE CHECKPOINT; CHROMOSOME PAIRING; DNA REPAIR; GENETIC RECOMBINATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; SIGNAL TRANSDUCTION;

SYNAPSIS;

ADENOSINE TRIPHOSPHATASES; ANIMALS; APOPTOSIS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CHECKPOINT KINASE 2; CHROMOSOME PAIRING; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; MALE; MICE; MUTATION; NUCLEAR PROTEINS; PACHYTENE STAGE; RECOMBINATION, GENETIC; SIGNAL TRANSDUCTION; SPERMATOCYTES;

EID: 84926140145     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005017     Document Type: Article

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