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Volumn 15, Issue 1, 2004, Pages 11-23

Mek1 Kinase Activity Functions Downstream of RED1 in the Regulation of Meiotic Double Strand Break Repair in Budding Yeast

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DMC1 PROTEIN; DOUBLE STRANDED DNA; HOP1 PROTEIN; M PROTEIN; MEK1 PROTEIN KINASE; PHOSPHOTHREONINE; PROTEIN KINASE C INHIBITOR; RECA PROTEIN; RED1 PROTEIN; UNCLASSIFIED DRUG;

EID: 0347990577     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E03-07-0499     Document Type: Article
Times cited : (107)

References (47)
  • 1
    • 0035854342 scopus 로고    scopus 로고
    • Differential timing and control of noncrossover and crossover recombination during meiosis
    • Allers, T., and Lichten, M. (2001). Differential timing and control of noncrossover and crossover recombination during meiosis. Cell 106, 47-57.
    • (2001) Cell , vol.106 , pp. 47-57
    • Allers, T.1    Lichten, M.2
  • 2
    • 0033522410 scopus 로고    scopus 로고
    • Sister chromatid-based DNA repair is mediated by RAD54, not by DMC1 or. TID1
    • Arbel, A., Zenvirth, D., and Simchen, G. (1999). Sister chromatid-based DNA repair is mediated by RAD54, not by DMC1 or. TID1. EMBO J. 18, 2648-2658.
    • (1999) EMBO J. , vol.18 , pp. 2648-2658
    • Arbel, A.1    Zenvirth, D.2    Simchen, G.3
  • 3
    • 0032533905 scopus 로고    scopus 로고
    • Synaptonemal complex morphogenesis and sister-chromatid cohesion require Mek1-dependent phosphorylation of a meiotic chromosomal protein
    • Bailis, J.M., and Roeder, G.S. (1998). Synaptonemal complex morphogenesis and sister-chromatid cohesion require Mek1-dependent phosphorylation of a meiotic chromosomal protein. Genes Dev. 12, 3551-3563.
    • (1998) Genes Dev. , vol.12 , pp. 3551-3563
    • Bailis, J.M.1    Roeder, G.S.2
  • 4
    • 0034646510 scopus 로고    scopus 로고
    • Pachytene exit controlled by reversal of Mek1-dependent phosphorylation
    • Bailis, J.M., and Roeder, G.S. (2000). Pachytene exit controlled by reversal of Mek1-dependent phosphorylation. Cell 101, 211-221.
    • (2000) Cell , vol.101 , pp. 211-221
    • Bailis, J.M.1    Roeder, G.S.2
  • 5
    • 0034082263 scopus 로고    scopus 로고
    • Bypass of a meiotic checkpoint by overproduction of meiotic chromosomal proteins
    • Bailis, J.M., Smith, A.V., and Roeder, G.S. (2000). Bypass of a meiotic checkpoint by overproduction of meiotic chromosomal proteins. Mol. Cell. Biol. 20, 4838-4848.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4838-4848
    • Bailis, J.M.1    Smith, A.V.2    Roeder, G.S.3
  • 6
    • 0030632241 scopus 로고    scopus 로고
    • Chiasmata, crossovers and meiotic chromosome segregation
    • Bascom-Slack, C.A., Ross, L.O., and Dawson, D.S. (1997). Chiasmata, crossovers and meiotic chromosome segregation. Adv. Genetics 35, 253-284.
    • (1997) Adv. Genetics , vol.35 , pp. 253-284
    • Bascom-Slack, C.A.1    Ross, L.O.2    Dawson, D.S.3
  • 8
    • 0028600050 scopus 로고
    • RecA homologs Dmcl and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis
    • Bishop, D.K. (1994). RecA homologs Dmcl and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis. Cell 79, 1081-1092.
    • (1994) Cell , vol.79 , pp. 1081-1092
    • Bishop, D.K.1
  • 9
    • 0032755420 scopus 로고    scopus 로고
    • High copy number suppression of the meiotic arrest caused by a dmc1 mutation: REC114 imposes an early recombination block and RAD54 promotes a DMC1-independent DSB repair pathway
    • Bishop, D.K., Nikolski, Y., Oshiro, J., Chon, J., Shinohara, M., and Chen, X. (1999). High copy number suppression of the meiotic arrest caused by a dmc1 mutation: REC114 imposes an early recombination block and RAD54 promotes a DMC1-independent DSB repair pathway. Genes Cells 4, 425-443.
    • (1999) Genes Cells , vol.4 , pp. 425-443
    • Bishop, D.K.1    Nikolski, Y.2    Oshiro, J.3    Chon, J.4    Shinohara, M.5    Chen, X.6
  • 10
    • 0026697166 scopus 로고
    • DMC1: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation and cell cycle progression
    • Bishop, D.K., Park, D., Xu, L., and Kleckner, N. (1992). DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation and cell cycle progression. Cell 69, 439-456.
    • (1992) Cell , vol.69 , pp. 439-456
    • Bishop, D.K.1    Park, D.2    Xu, L.3    Kleckner, N.4
  • 11
    • 0035584046 scopus 로고    scopus 로고
    • Replication protein A is sequentially phosphorylated during meiosis
    • Brush, G.S., Clifford, D.M., Marinco, S.M., and Bartrand, A.J. (2001). Replication protein A is sequentially phosphorylated during meiosis. Nucleic Acids Res. 29, 4808-4817.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4808-4817
    • Brush, G.S.1    Clifford, D.M.2    Marinco, S.M.3    Bartrand, A.J.4
  • 12
    • 0033555552 scopus 로고    scopus 로고
    • Red1p: A MEK1-dependent phosphoprotein that physically interacts with Hop1p during meiosis in yeast
    • de los Santos, T., and Hollingsworth, N.M. (1999). Red1p: a MEK1-dependent phosphoprotein that physically interacts with Hop1p during meiosis in yeast. J. Biol. Chem. 274, 1783-1790.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1783-1790
    • De Los Santos, T.1    Hollingsworth, N.M.2
  • 14
    • 0033197541 scopus 로고    scopus 로고
    • The FHA domain is a modular phosphopep tide recognition motif
    • Durocher, D., Henckel, J., Fersht, A.R., and Jackson, S.P. (1999). The FHA domain is a modular phosphopep tide recognition motif. Mol Cell 4, 387-394.
    • (1999) Mol Cell , vol.4 , pp. 387-394
    • Durocher, D.1    Henckel, J.2    Fersht, A.R.3    Jackson, S.P.4
  • 15
    • 0033638454 scopus 로고    scopus 로고
    • The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phosphodependent signaling mechanisms
    • Durocher, D., Taylor, I.A., Sarbassova, D., Haire, L.F., Westcott, S.L., Jackson, S.P., Smerdon, S.J., and Yaffe, M.B. (2000). The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phosphodependent signaling mechanisms. Mol. Cell 6, 1169-1182.
    • (2000) Mol. Cell , vol.6 , pp. 1169-1182
    • Durocher, D.1    Taylor, I.A.2    Sarbassova, D.3    Haire, L.F.4    Westcott, S.L.5    Jackson, S.P.6    Smerdon, S.J.7    Yaffe, M.B.8
  • 16
    • 0025004280 scopus 로고
    • Meiotic gene conversion and crossing over: Their relationship to each other and to chromosome synapsis and segregation
    • Engebrecht, J., Hirsch, J., and Roeder, G.S. (1990). Meiotic gene conversion and crossing over: their relationship to each other and to chromosome synapsis and segregation. Cell 62, 927-937.
    • (1990) Cell , vol.62 , pp. 927-937
    • Engebrecht, J.1    Hirsch, J.2    Roeder, G.S.3
  • 17
    • 0027528786 scopus 로고
    • A conditional allele of the Saccharomyces cerevisiae HOP1 gene is suppressed by over-expression of two other meiosis-specific genes, RED1, and REC104
    • Hollingsworth, N.M., and Johnson, A.D. (1993). A conditional allele of the Saccharomyces cerevisiae HOP1 gene is suppressed by over-expression of two other meiosis-specific genes, RED1, and REC104. Genetics 133, 785-797.
    • (1993) Genetics , vol.133 , pp. 785-797
    • Hollingsworth, N.M.1    Johnson, A.D.2
  • 18
    • 0024635860 scopus 로고
    • HOP1: A yeast meiotic pairing gene
    • Hollingsworth, N.M., and Byers, B. (1989). HOP1: a yeast meiotic pairing gene. Genetics 121, 445-462.
    • (1989) Genetics , vol.121 , pp. 445-462
    • Hollingsworth, N.M.1    Byers, B.2
  • 19
    • 0030930119 scopus 로고    scopus 로고
    • Genetic interactions between HOP1, RED1 and MEK1 suggest that MEK1 regulates assembly of axial element components during meiosis in the yeast, Saccharomyces cerevisiae
    • Hollingsworth, N.M., and Ponte, L. (1997). Genetic interactions between HOP1, RED1 and MEK1 suggest that MEK1 regulates assembly of axial element components during meiosis in the yeast, Saccharomyces cerevisiae. Genetics 147, 33-42.
    • (1997) Genetics , vol.147 , pp. 33-42
    • Hollingsworth, N.M.1    Ponte, L.2
  • 20
    • 0029145505 scopus 로고
    • MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair
    • Hollingsworth, N.M., Ponte, L., and Halsey, C. (1995). MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair. Genes Dev. 9, 1728-1739.
    • (1995) Genes Dev. , vol.9 , pp. 1728-1739
    • Hollingsworth, N.M.1    Ponte, L.2    Halsey, C.3
  • 21
    • 0035854362 scopus 로고    scopus 로고
    • The single-end invasion: An asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombination
    • Hunter, N., and Kleckner, N. (2001). The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombination. Cell 106, 59-70.
    • (2001) Cell , vol.106 , pp. 59-70
    • Hunter, N.1    Kleckner, N.2
  • 22
    • 0029993727 scopus 로고    scopus 로고
    • Active and inactive protein kinases: Structural basis for regulation
    • Johnson, L.N., Noble, M.E.M., and Owen, D.J. (1996). Active and inactive protein kinases: structural basis for regulation. Cell 19, 149-158.
    • (1996) Cell , vol.19 , pp. 149-158
    • Johnson, L.N.1    Noble, M.E.M.2    Owen, D.J.3
  • 23
    • 0035223878 scopus 로고    scopus 로고
    • Mechanism and control of meiotic recombination initiation
    • Keeney, S. (2001). Mechanism and control of meiotic recombination initiation. Curr. Top. Dev. Biol. 52, 1-53.
    • (2001) Curr. Top. Dev. Biol. , vol.52 , pp. 1-53
    • Keeney, S.1
  • 24
    • 0029080942 scopus 로고
    • Members of the NAP/SET family of proteins interact specifically with B-type cyclins
    • Kellogg, D.R., Kikuchi, A., Fujii-Nakata, T., Turck, C.W., and Murray, A.W. (1995). Members of the NAP/SET family of proteins interact specifically with B-type cyclins. J. Cell Biol. 130, 661-673.
    • (1995) J. Cell Biol. , vol.130 , pp. 661-673
    • Kellogg, D.R.1    Kikuchi, A.2    Fujii-Nakata, T.3    Turck, C.W.4    Murray, A.W.5
  • 25
    • 2642703473 scopus 로고    scopus 로고
    • DNA-binding properties of Hop1 protein, a synaptonemal complex component from Saccharomyces cerevisiae
    • Kironmai, K.M., Muniyappa, K., Friedman, D.B., Hollingsworth, N.M., and Byers, B. (1998). DNA-binding properties of Hop1 protein, a synaptonemal complex component from Saccharomyces cerevisiae. Mol. Cell. Biol. 18, 1424-1435.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1424-1435
    • Kironmai, K.M.1    Muniyappa, K.2    Friedman, D.B.3    Hollingsworth, N.M.4    Byers, B.5
  • 26
    • 0026567640 scopus 로고
    • The MRE4 gene encodes a novel protein kinase homologue required for meiotic recombination in Saccharomyces cerevisiae
    • Leem, S.-H., and Ogawa, H. (1992). The MRE4 gene encodes a novel protein kinase homologue required for meiotic recombination in Saccharomyces cerevisiae. Nucleic Acids Res. 20, 449-457.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 449-457
    • Leem, S.-H.1    Ogawa, H.2
  • 29
    • 0033968862 scopus 로고    scopus 로고
    • Yeast meiosis-specific protein Hop1 binds to G4 DNA and promotes its formation
    • Muniyappa, K., Anuradha, S., and Byers, B. (2000). Yeast meiosis-specific protein Hop1 binds to G4 DNA and promotes its formation. Mol. Cell. Biol. 20, 1361-1369.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1361-1369
    • Muniyappa, K.1    Anuradha, S.2    Byers, B.3
  • 31
    • 0032832810 scopus 로고    scopus 로고
    • Yeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA double helix conformation
    • Petukhova, G., Van Komen, S., Vergano, S., Klein, H., and Sung, P. (1999). Yeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA double helix conformation. J. Biol. Chem. 274, 29453-29462.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29453-29462
    • Petukhova, G.1    Van Komen, S.2    Vergano, S.3    Klein, H.4    Sung, P.5
  • 32
    • 0025169583 scopus 로고
    • Meiosis in asynaptic yeast
    • Rockmill, B., and Roeder, G.S. (1990). Meiosis in asynaptic yeast. Genetics 126, 563-574.
    • (1990) Genetics , vol.126 , pp. 563-574
    • Rockmill, B.1    Roeder, G.S.2
  • 33
    • 0026267294 scopus 로고
    • A meiosis-specific protein kinase homologue required for chromosome synapsis and recombination
    • Rockmill, B., and Roeder, G.S. (1991). A meiosis-specific protein kinase homologue required for chromosome synapsis and recombination. Genes Dev. 5, 2392-2404.
    • (1991) Genes Dev. , vol.5 , pp. 2392-2404
    • Rockmill, B.1    Roeder, G.S.2
  • 34
    • 0034284084 scopus 로고    scopus 로고
    • The pachytene checkpoint
    • Roeder, G.S., and Bailis, J.M. (2000). The pachytene checkpoint. Trends Genet. 16, 395-403.
    • (2000) Trends Genet. , vol.16 , pp. 395-403
    • Roeder, G.S.1    Bailis, J.M.2
  • 35
    • 0030886852 scopus 로고    scopus 로고
    • Interhomolog bias during meiotic recombination: Meiotic functions promote a highly differentiated interhomolog-only pathway
    • Schwacha, A., and Kleckner, N. (1997). Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell 90, 1123-1135.
    • (1997) Cell , vol.90 , pp. 1123-1135
    • Schwacha, A.1    Kleckner, N.2
  • 36
    • 0036008093 scopus 로고    scopus 로고
    • A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway
    • Shah, K., and Shokat, K. (2002). A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway. Chem. Biol. 9, 35-47.
    • (2002) Chem. Biol. , vol.9 , pp. 35-47
    • Shah, K.1    Shokat, K.2
  • 37
    • 0030899885 scopus 로고    scopus 로고
    • The yeast Red1 protein localizes to the cores of meiotic chromosomes
    • Smith, A.V., and Roeder, G.S. (1997). The yeast Red1 protein localizes to the cores of meiotic chromosomes. J. Cell Biol. 136, 957-967.
    • (1997) J. Cell Biol. , vol.136 , pp. 957-967
    • Smith, A.V.1    Roeder, G.S.2
  • 38
    • 0027502061 scopus 로고
    • ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis
    • Sym, M., Engebrecht, J., and Roeder, G.S. (1993). ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis. Cell 72, 365-378.
    • (1993) Cell , vol.72 , pp. 365-378
    • Sym, M.1    Engebrecht, J.2    Roeder, G.S.3
  • 39
    • 0036900120 scopus 로고    scopus 로고
    • Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair
    • Symington, L.S. (2002). Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol. Mol. Biol. Rev. 66, 630-670.
    • (2002) Microbiol. Mol. Biol. Rev. , vol.66 , pp. 630-670
    • Symington, L.S.1
  • 40
    • 0032820031 scopus 로고    scopus 로고
    • Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination
    • Thompson, D.A., and Stahl, F.W. (1999). Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination. Genetics 153, 621-641.
    • (1999) Genetics , vol.153 , pp. 621-641
    • Thompson, D.A.1    Stahl, F.W.2
  • 41
    • 0024309056 scopus 로고
    • Expression and DNA sequence of RED1, a gene required for meiosis I chromosome segregation in yeast
    • Thompson, E.A., and Roeder, G.S. (1989). Expression and DNA sequence of RED1, a gene required for meiosis I chromosome segregation in yeast. Mol. Gen. Genet. 218, 293-301.
    • (1989) Mol. Gen. Genet. , vol.218 , pp. 293-301
    • Thompson, E.A.1    Roeder, G.S.2
  • 42
    • 0026641668 scopus 로고
    • Meiotic induction of the yeast HOP1 gene is controlled by positive and negative regulatory elements
    • Vershon, A.K., Hollingsworth, N.M., and Johnson, A.D. (1992). Meiotic induction of the yeast HOP1 gene is controlled by positive and negative regulatory elements. Mol. Cell. Biol. 12, 3706-3714.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3706-3714
    • Vershon, A.K.1    Hollingsworth, N.M.2    Johnson, A.D.3
  • 43
    • 0036008090 scopus 로고    scopus 로고
    • Mutant tyrosine kinases with unnatural nucleotide specificity retain the structure and phospho-acceptor specificity of the wild-type enzyme
    • Witucki, L.A., Huang, X., Shah, K., Liu, Y., Kyin, S., Eck, M.J., and Shokat, K. (2002). Mutant tyrosine kinases with unnatural nucleotide specificity retain the structure and phospho-acceptor specificity of the wild-type enzyme. Chem. Biol. 9, 25-33.
    • (2002) Chem. Biol. , vol.9 , pp. 25-33
    • Witucki, L.A.1    Huang, X.2    Shah, K.3    Liu, Y.4    Kyin, S.5    Eck, M.J.6    Shokat, K.7
  • 44
    • 0033816350 scopus 로고    scopus 로고
    • Meiotic segregation, synapsis, and recombination checkpoint functions require physical interaction between the chromosomal proteins Red1p and Hop1p
    • Woltering, D., Baumgartner, B., Bagchi, S., Larkin, B., Loidl, J., de los Santos, T., and Hollingsworth, N.M. (2000). Meiotic segregation, synapsis, and recombination checkpoint functions require physical interaction between the chromosomal proteins Red1p and Hop1p. Mol. Cell. Biol. 20, 6646-6658.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 6646-6658
    • Woltering, D.1    Baumgartner, B.2    Bagchi, S.3    Larkin, B.4    Loidl, J.5    De Los Santos, T.6    Hollingsworth, N.M.7
  • 45
    • 0028206864 scopus 로고
    • Meiosis-induced double-strand break sites determined by yeast chromatin structure
    • Wu, T.-C., and Lichten, M. (1994). Meiosis-induced double-strand break sites determined by yeast chromatin structure. Science 263, 515-518.
    • (1994) Science , vol.263 , pp. 515-518
    • Wu, T.-C.1    Lichten, M.2
  • 46
    • 0031027869 scopus 로고    scopus 로고
    • Meiotic cells monitor the status of the interhomolog recombination complex
    • Xu, L., Weiner, B.M., and Kleckner, N. (1997). Meiotic cells monitor the status of the interhomolog recombination complex. Genes Dev. 11, 106-118.
    • (1997) Genes Dev. , vol.11 , pp. 106-118
    • Xu, L.1    Weiner, B.M.2    Kleckner, N.3
  • 47
    • 0035252918 scopus 로고    scopus 로고
    • The Rad51 and Dmc1 recombinases: A non-identical twin relationship
    • Yves-Masson, J., and West, S.C. (2001). The Rad51 and Dmc1 recombinases: a non-identical twin relationship. Trends Biochem. Sci. 26, 131-136.
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 131-136
    • Yves-Masson, J.1    West, S.C.2


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