메뉴 건너뛰기




Volumn 10, Issue 3, 2015, Pages

JSI-124 suppresses invasion and angiogenesis of glioblastoma cells In Vitro

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; CD34 ANTIGEN; CUCURBITACIN I; KI 67 ANTIGEN; STAT3 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; TRITERPENE; VASCULOTROPIN A;

EID: 84926041536     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118894     Document Type: Article
Times cited : (23)

References (51)
  • 1
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • PMID: 17618441
    • Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, et al. (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114: 97-109. PMID: 17618441
    • (2007) Acta Neuropathol , vol.114 , pp. 97-109
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3    Cavenee, W.K.4    Burger, P.C.5
  • 2
    • 77950021940 scopus 로고    scopus 로고
    • BmKCT toxin inhibits glioma proliferation and tumor metastasis
    • PMID: 19906483
    • Fan S, Sun Z, Jiang D, Dai C, Ma Y, et al. (2010) BmKCT toxin inhibits glioma proliferation and tumor metastasis. Cancer Lett 291: 158-166. doi: 10.1016/j.canlet.2009.10.011 PMID: 19906483
    • (2010) Cancer Lett , vol.291 , pp. 158-166
    • Fan, S.1    Sun, Z.2    Jiang, D.3    Dai, C.4    Ma, Y.5
  • 3
    • 0036490612 scopus 로고    scopus 로고
    • Focus on central nervous system neoplasia
    • PMID: 12086870
    • Louis DN, Pomeroy SL, Cairncross JG (2002) Focus on central nervous system neoplasia. Cancer Cell 1: 125-128. PMID: 12086870
    • (2002) Cancer Cell , vol.1 , pp. 125-128
    • Louis, D.N.1    Pomeroy, S.L.2    Cairncross, J.G.3
  • 4
    • 34447343798 scopus 로고    scopus 로고
    • Lessons learned in the development of targeted therapy for malignant gliomas
    • PMID: 17620423
    • Omuro AM, Faivre S, Raymond E (2007) Lessons learned in the development of targeted therapy for malignant gliomas. Mol Cancer Ther 6: 1909-1919. PMID: 17620423
    • (2007) Mol Cancer Ther , vol.6 , pp. 1909-1919
    • Omuro, A.M.1    Faivre, S.2    Raymond, E.3
  • 5
    • 0030701960 scopus 로고    scopus 로고
    • Halting angiogenesis suppresses carcinoma cell invasion
    • PMID: 9359696
    • Skobe M, Rockwell P, Goldstein N, Vosseler S, Fusenig NE (1997) Halting angiogenesis suppresses carcinoma cell invasion. Nat Med 3: 1222-1227. PMID: 9359696
    • (1997) Nat Med , vol.3 , pp. 1222-1227
    • Skobe, M.1    Rockwell, P.2    Goldstein, N.3    Vosseler, S.4    Fusenig, N.E.5
  • 6
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • PMID: 7584949
    • Folkman J (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1: 27-31. PMID: 7584949
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 7
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • PMID: 10647931
    • Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100: 57-70. PMID: 10647931
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 77954668887 scopus 로고    scopus 로고
    • Angiogenesis inhibitors: Current strategies and future prospects
    • PMID: 20554717
    • Cook KM, Figg WD (2010) Angiogenesis inhibitors: current strategies and future prospects. CA Cancer J Clin 60: 222-243. doi: 10.3322/caac.20075 PMID: 20554717
    • (2010) CA Cancer J Clin , vol.60 , pp. 222-243
    • Cook, K.M.1    Figg, W.D.2
  • 9
    • 79951550507 scopus 로고    scopus 로고
    • Angiogenesis and invasion in glioma
    • PMID: 21221826
    • Onishi M, Ichikawa T, Kurozumi K, Date I (2011) Angiogenesis and invasion in glioma. Brain Tumor Pathol 28: 13-24. doi: 10.1007/s10014-010-0007-z PMID: 21221826
    • (2011) Brain Tumor Pathol , vol.28 , pp. 13-24
    • Onishi, M.1    Ichikawa, T.2    Kurozumi, K.3    Date, I.4
  • 11
    • 84867504682 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 promotes angiogenesis and drives malignant progression in glioma
    • PMID: 22753228
    • Doucette TA, Kong LY, Yang Y, Ferguson SD, Yang J, et al. (2012) Signal transducer and activator of transcription 3 promotes angiogenesis and drives malignant progression in glioma. Neuro Oncol 14: 1136-1145. doi: 10.1093/neuonc/nos139 PMID: 22753228
    • (2012) Neuro Oncol , vol.14 , pp. 1136-1145
    • Doucette, T.A.1    Kong, L.Y.2    Yang, Y.3    Ferguson, S.D.4    Yang, J.5
  • 12
    • 84868611960 scopus 로고    scopus 로고
    • Modulating antiangiogenic resistance by inhibiting the signal transducer and activator of transcription 3 pathway in glioblastoma
    • PMID: 23013619
    • de Groot J, Liang J, Kong LY, Wei J, Piao Y, et al. (2012) Modulating antiangiogenic resistance by inhibiting the signal transducer and activator of transcription 3 pathway in glioblastoma. Oncotarget 3: 1036-1048. PMID: 23013619
    • (2012) Oncotarget , vol.3 , pp. 1036-1048
    • De Groot, J.1    Liang, J.2    Kong, L.Y.3    Wei, J.4    Piao, Y.5
  • 13
    • 39549102220 scopus 로고    scopus 로고
    • STAT3: A critical transcription activator in angiogenesis
    • PMID: 17457812
    • Chen Z, Han ZC (2008) STAT3: a critical transcription activator in angiogenesis. Med Res Rev 28: 185-200. PMID: 17457812
    • (2008) Med Res Rev , vol.28 , pp. 185-200
    • Chen, Z.1    Han, Z.C.2
  • 14
    • 23444449093 scopus 로고    scopus 로고
    • STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells
    • PMID: 15919761
    • Jung JE, Lee HG, Cho IH, Chung DH, Yoon SH, et al. (2005) STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells. FASEB J 19: 1296-1298. PMID: 15919761
    • (2005) FASEB J , vol.19 , pp. 1296-1298
    • Jung, J.E.1    Lee, H.G.2    Cho, I.H.3    Chung, D.H.4    Yoon, S.H.5
  • 15
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • PMID: 11948098
    • Buettner R, Mora LB, Jove R (2002) Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8: 945-954. PMID: 11948098
    • (2002) Clin Cancer Res , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 16
    • 1442285917 scopus 로고    scopus 로고
    • Inactivation of Stat3 in tumor cells: Releasing a brake on immune responses against cancer?
    • PMID: 14998485
    • Gamero AM, Young HA, Wiltrout RH (2004) Inactivation of Stat3 in tumor cells: releasing a brake on immune responses against cancer? Cancer Cell 5: 111-112. PMID: 14998485
    • (2004) Cancer Cell , vol.5 , pp. 111-112
    • Gamero, A.M.1    Young, H.A.2    Wiltrout, R.H.3
  • 17
    • 84878432714 scopus 로고    scopus 로고
    • OPB-31121, a novel small molecular inhibitor, disrupts the JAK2/STAT3 pathway and exhibits an antitumor activity in gastric cancer cells
    • PMID: 23402820
    • Kim MJ, Nam HJ, Kim HP, Han SW, Im SA, et al. (2013) OPB-31121, a novel small molecular inhibitor, disrupts the JAK2/STAT3 pathway and exhibits an antitumor activity in gastric cancer cells. Cancer Lett 335: 145-152. doi: 10.1016/j.canlet.2013.02.010 PMID: 23402820
    • (2013) Cancer Lett , vol.335 , pp. 145-152
    • Kim, M.J.1    Nam, H.J.2    Kim, H.P.3    Han, S.W.4    Im, S.A.5
  • 18
    • 34548693457 scopus 로고    scopus 로고
    • Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells
    • PMID: 17855663
    • Pathak AK, Bhutani M, Nair AS, Ahn KS, Chakraborty A, et al. (2007) Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells. Mol Cancer Res 5: 943-955. PMID: 17855663
    • (2007) Mol Cancer Res , vol.5 , pp. 943-955
    • Pathak, A.K.1    Bhutani, M.2    Nair, A.S.3    Ahn, K.S.4    Chakraborty, A.5
  • 19
    • 49749129612 scopus 로고    scopus 로고
    • JSI-124 inhibits glioblastoma multiforme cell proliferation through G(2)/M cell cycle arrest and apoptosis augment
    • PMID: 18487947
    • Su Y, Li G, Zhang X, Gu J, Zhang C, et al. (2008) JSI-124 inhibits glioblastoma multiforme cell proliferation through G(2)/M cell cycle arrest and apoptosis augment. Cancer Biol Ther 7: 1243-1249. PMID: 18487947
    • (2008) Cancer Biol Ther , vol.7 , pp. 1243-1249
    • Su, Y.1    Li, G.2    Zhang, X.3    Gu, J.4    Zhang, C.5
  • 20
    • 69349095364 scopus 로고    scopus 로고
    • Anticancer strategies involving the vasculature
    • PMID: 19424102
    • Heath VL, Bicknell R (2009) Anticancer strategies involving the vasculature. Nat Rev Clin Oncol 6: 395-404. doi: 10.1038/nrclinonc.2009.52 PMID: 19424102
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 395-404
    • Heath, V.L.1    Bicknell, R.2
  • 21
    • 0037444373 scopus 로고    scopus 로고
    • Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice
    • PMID: 12649187
    • Blaskovich MA, Sun J, Cantor A, Turkson J, Jove R, et al. (2003) Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Cancer Res 63: 1270-1279. PMID: 12649187
    • (2003) Cancer Res , vol.63 , pp. 1270-1279
    • Blaskovich, M.A.1    Sun, J.2    Cantor, A.3    Turkson, J.4    Jove, R.5
  • 22
    • 20844444135 scopus 로고    scopus 로고
    • Targeting Stat3 in cancer therapy
    • PMID: 15930886
    • Jing N, Tweardy DJ (2005) Targeting Stat3 in cancer therapy. Anticancer Drugs 16: 601-607. PMID: 15930886
    • (2005) Anticancer Drugs , vol.16 , pp. 601-607
    • Jing, N.1    Tweardy, D.J.2
  • 23
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • PMID: 9630216
    • Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, et al. (1998) Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 93: 705-716. PMID: 9630216
    • (1998) Cell , vol.93 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5
  • 24
    • 0032852528 scopus 로고    scopus 로고
    • Molecular and biological properties of vascular endothelial growth factor
    • PMID: 10494799
    • Ferrara N (1999) Molecular and biological properties of vascular endothelial growth factor. J Mol Med (Berl) 77: 527-543. PMID: 10494799
    • (1999) J Mol Med (Berl) , vol.77 , pp. 527-543
    • Ferrara, N.1
  • 25
    • 0033119833 scopus 로고    scopus 로고
    • Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function
    • PMID: 10197634
    • Grunstein J, Roberts WG, Mathieu-Costello O, Hanahan D, Johnson RS (1999) Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function. Cancer Res 59: 1592-1598. PMID: 10197634
    • (1999) Cancer Res , vol.59 , pp. 1592-1598
    • Grunstein, J.1    Roberts, W.G.2    Mathieu-Costello, O.3    Hanahan, D.4    Johnson, R.S.5
  • 26
    • 0033580889 scopus 로고    scopus 로고
    • Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
    • PMID: 10373119
    • Holash J, Maisonpierre PC, Compton D, Boland P, Alexander CR, et al. (1999) Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 284: 1994-1998. PMID: 10373119
    • (1999) Science , vol.284 , pp. 1994-1998
    • Holash, J.1    Maisonpierre, P.C.2    Compton, D.3    Boland, P.4    Alexander, C.R.5
  • 27
    • 33746858881 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-Receptor2: Its biological functions, major signaling pathway, and specific ligand VEGF-E
    • PMID: 16728325
    • Shibuya M (2006) Vascular endothelial growth factor (VEGF)-Receptor2: its biological functions, major signaling pathway, and specific ligand VEGF-E. Endothelium 13: 63-69. PMID: 16728325
    • (2006) Endothelium , vol.13 , pp. 63-69
    • Shibuya, M.1
  • 28
    • 2342430184 scopus 로고    scopus 로고
    • Vasculogenesis and angiogenesis
    • PMID: 15015550
    • Patan S (2004) Vasculogenesis and angiogenesis. Cancer Treat Res 117: 3-32. PMID: 15015550
    • (2004) Cancer Treat Res , vol.117 , pp. 3-32
    • Patan, S.1
  • 29
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • PMID: 12778165
    • Ferrara N, Gerber HP, LeCouter J (2003) The biology of VEGF and its receptors. Nat Med 9: 669-676. PMID: 12778165
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 30
    • 84863151419 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer
    • PMID: 22203730
    • Chen J, Wang J, Lin L, He L, Wu Y, et al. (2012) Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer. Mol Cancer Ther 11: 277-287. doi: 10.1158/1535-7163.MCT-11-0648 PMID: 22203730
    • (2012) Mol Cancer Ther , vol.11 , pp. 277-287
    • Chen, J.1    Wang, J.2    Lin, L.3    He, L.4    Wu, Y.5
  • 31
    • 84856085484 scopus 로고    scopus 로고
    • Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3)
    • PMID: 22280969
    • Kandala PK, Srivastava SK (2012) Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3). BMC Med 10: 9. doi: 10.1186/1741-7015-10-9 PMID: 22280969
    • (2012) BMC Med , vol.10 , pp. 9
    • Kandala, P.K.1    Srivastava, S.K.2
  • 32
    • 77950915623 scopus 로고    scopus 로고
    • Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling
    • PMID: 19969552
    • Lu J, Zhang K, Nam S, Anderson RA, Jove R, et al. (2010) Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling. Carcinogenesis 31: 481-488. doi: 10.1093/carcin/bgp292 PMID: 19969552
    • (2010) Carcinogenesis , vol.31 , pp. 481-488
    • Lu, J.1    Zhang, K.2    Nam, S.3    Anderson, R.A.4    Jove, R.5
  • 33
    • 78650488834 scopus 로고    scopus 로고
    • Inhibition of constitutive activation of STAT3 by curcurbitacin-I (JSI-124) sensitized human B-leukemia cells to apoptosis
    • PMID: 21159613
    • Ishdorj G, Johnston JB, Gibson SB (2010) Inhibition of constitutive activation of STAT3 by curcurbitacin-I (JSI-124) sensitized human B-leukemia cells to apoptosis. Mol Cancer Ther 9: 3302-3314. doi: 10.1158/1535-7163.MCT-10-0550 PMID: 21159613
    • (2010) Mol Cancer Ther , vol.9 , pp. 3302-3314
    • Ishdorj, G.1    Johnston, J.B.2    Gibson, S.B.3
  • 34
    • 84898640642 scopus 로고    scopus 로고
    • Cucurbitacin I induces protective autophagy in glioblastoma in vitro and in vivo
    • PMID: 24599950
    • Yuan G, Yan SF, Xue H, Zhang P, Sun JT, et al. (2014) Cucurbitacin I induces protective autophagy in glioblastoma in vitro and in vivo. J Biol Chem 289: 10607-10619. doi: 10.1074/jbc.M113.528760 PMID: 24599950
    • (2014) J Biol Chem , vol.289 , pp. 10607-10619
    • Yuan, G.1    Yan, S.F.2    Xue, H.3    Zhang, P.4    Sun, J.T.5
  • 36
    • 84867542188 scopus 로고    scopus 로고
    • Signaling determinants of glioma cell invasion
    • PMID: 22879067
    • Kwiatkowska A, Symons M (2013) Signaling determinants of glioma cell invasion. Adv Exp Med Biol 986: 121-141. doi: 10.1007/978-94-007-4719-7-7 PMID: 22879067
    • (2013) Adv Exp Med Biol , vol.986 , pp. 121-141
    • Kwiatkowska, A.1    Symons, M.2
  • 37
    • 35949002429 scopus 로고    scopus 로고
    • Malignant astrocytic glioma: Genetics, biology, and paths to treatment
    • PMID: 17974913
    • Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, et al. (2007) Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev 21: 2683-2710. PMID: 17974913
    • (2007) Genes Dev , vol.21 , pp. 2683-2710
    • Furnari, F.B.1    Fenton, T.2    Bachoo, R.M.3    Mukasa, A.4    Stommel, J.M.5
  • 38
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • PMID: 18463380
    • Kerbel RS (2008) Tumor angiogenesis. N Engl J Med 358: 2039-2049. doi: 10.1056/NEJMra0706596 PMID: 18463380
    • (2008) N Engl J Med , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 39
    • 84881667318 scopus 로고    scopus 로고
    • Anti-angiogenesis in cancer therapy: Hercules and hydra
    • PMID: 23707856
    • Bellou S, Pentheroudakis G, Murphy C, Fotsis T (2013) Anti-angiogenesis in cancer therapy: Hercules and hydra. Cancer Lett 338: 219-228. doi: 10.1016/j.canlet.2013.05.015 PMID: 23707856
    • (2013) Cancer Lett , vol.338 , pp. 219-228
    • Bellou, S.1    Pentheroudakis, G.2    Murphy, C.3    Fotsis, T.4
  • 40
    • 27944473690 scopus 로고    scopus 로고
    • VEGF as a key mediator of angiogenesis in cancer
    • PMID: 16301830
    • Carmeliet P (2005) VEGF as a key mediator of angiogenesis in cancer. Oncology 69 Suppl 3: 4-10. PMID: 16301830
    • (2005) Oncology , vol.69 , pp. 4-10
    • Carmeliet, P.1
  • 41
    • 0034757675 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression correlates with tumour grade and vascularity in gliomas
    • PMID: 11683943
    • Chaudhry IH, O'Donovan DG, Brenchley PE, Reid H, Roberts IS (2001) Vascular endothelial growth factor expression correlates with tumour grade and vascularity in gliomas. Histopathology 39: 409-415. PMID: 11683943
    • (2001) Histopathology , vol.39 , pp. 409-415
    • Chaudhry, I.H.1    O'Donovan, D.G.2    Brenchley, P.E.3    Reid, H.4    Roberts, I.S.5
  • 42
    • 0034467330 scopus 로고    scopus 로고
    • Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs
    • PMID: 11245272
    • Dunn IF, Heese O, Black PM (2000) Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs. J Neurooncol 50: 121-137. PMID: 11245272
    • (2000) J Neurooncol , vol.50 , pp. 121-137
    • Dunn, I.F.1    Heese, O.2    Black, P.M.3
  • 43
    • 33748051406 scopus 로고    scopus 로고
    • Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
    • PMID: 16912155
    • Bao S, Wu Q, Sathornsumetee S, Hao Y, Li Z, et al. (2006) Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res 66: 7843-7848. PMID: 16912155
    • (2006) Cancer Res , vol.66 , pp. 7843-7848
    • Bao, S.1    Wu, Q.2    Sathornsumetee, S.3    Hao, Y.4    Li, Z.5
  • 44
    • 0034470387 scopus 로고    scopus 로고
    • VEGF in brain tumors
    • PMID: 11245271
    • Machein MR, Plate KH (2000) VEGF in brain tumors. J Neurooncol 50: 109-120. PMID: 11245271
    • (2000) J Neurooncol , vol.50 , pp. 109-120
    • Machein, M.R.1    Plate, K.H.2
  • 45
    • 0035704913 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor in angiogenesis
    • PMID: 11815711
    • Ferrara N, Gerber HP (2001) The role of vascular endothelial growth factor in angiogenesis. Acta Haematol 106: 148-156. PMID: 11815711
    • (2001) Acta Haematol , vol.106 , pp. 148-156
    • Ferrara, N.1    Gerber, H.P.2
  • 46
    • 0029047695 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: An important mediator of angiogenesis in malignancy and inflammation
    • PMID: 7542074
    • Dvorak HF, Detmar M, Claffey KP, Nagy JA, van de Water L, et al. (1995) Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation. Int Arch Allergy Immunol 107: 233-235. PMID: 7542074
    • (1995) Int Arch Allergy Immunol , vol.107 , pp. 233-235
    • Dvorak, H.F.1    Detmar, M.2    Claffey, K.P.3    Nagy, J.A.4    Van De Water, L.5
  • 47
    • 0032889698 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis
    • PMID: 9893348
    • Dvorak HF, Nagy JA, Feng D, Brown LF, Dvorak AM (1999) Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis. Curr Top Microbiol Immunol 237: 97-132. PMID: 9893348
    • (1999) Curr Top Microbiol Immunol , vol.237 , pp. 97-132
    • Dvorak, H.F.1    Nagy, J.A.2    Feng, D.3    Brown, L.F.4    Dvorak, A.M.5
  • 48
    • 0035895711 scopus 로고    scopus 로고
    • Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
    • PMID: 11166270
    • Zachary I, Gliki G (2001) Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc Res 49: 568-581. PMID: 11166270
    • (2001) Cardiovasc Res , vol.49 , pp. 568-581
    • Zachary, I.1    Gliki, G.2
  • 49
    • 84875270769 scopus 로고    scopus 로고
    • Brucine, an indole alkaloid from Strychnos nux-vomica attenuates VEGF-induced angiogenesis via inhibiting VEGFR2 signaling pathway in vitro and in vivo
    • PMID: 23348691
    • Saraswati S, Agrawal SS (2013) Brucine, an indole alkaloid from Strychnos nux-vomica attenuates VEGF-induced angiogenesis via inhibiting VEGFR2 signaling pathway in vitro and in vivo. Cancer Lett 332: 83-93. doi: 10.1016/j.canlet.2013.01.012 PMID: 23348691
    • (2013) Cancer Lett , vol.332 , pp. 83-93
    • Saraswati, S.1    Agrawal, S.S.2
  • 50
    • 77953611845 scopus 로고    scopus 로고
    • Sorafenib exerts anti-glioma activity in vitro and in vivo
    • PMID: 20470863
    • Siegelin MD, Raskett CM, Gilbert CA, Ross AH, Altieri DC (2010) Sorafenib exerts anti-glioma activity in vitro and in vivo. Neurosci Lett 478: 165-170. doi: 10.1016/j.neulet.2010.05.009 PMID: 20470863
    • (2010) Neurosci Lett , vol.478 , pp. 165-170
    • Siegelin, M.D.1    Raskett, C.M.2    Gilbert, C.A.3    Ross, A.H.4    Altieri, D.C.5
  • 51
    • 0037064121 scopus 로고    scopus 로고
    • ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner
    • PMID: 11940572
    • Ren Z, Schaefer TS (2002) ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner. J Biol Chem 277: 38486-38493. PMID: 11940572
    • (2002) J Biol Chem , vol.277 , pp. 38486-38493
    • Ren, Z.1    Schaefer, T.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.