Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds

International Journal for Parasitology: Drugs and Drug Resistance

Volumn 5, Issue 2, 2015, Pages 37-43

  Müller, Joachim ^a   Rout, Samuel ^b   Leitsch, David ^a   Vaithilingam, Jathana ^a   Hehl, Adrian ^b   Müller, Norbert ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Functional assays; Mode of action of nitro compounds; Nitroreduction

Indexed keywords

FLAVINE ADENINE NUCLEOTIDE; METRONIDAZOLE; NITAZOXANIDE; NITRO DERIVATIVE; NITROREDUCTASE; NITROREDUCTASE GLNR1; NITROREDUCTASE GLNR2; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG; NICOTINAMIDE ADENINE DINUCLEOTIDE; RECOMBINANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ARTICLE; BACTERIAL GROWTH; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; GIARDIA INTESTINALIS; NONHUMAN; PRIORITY JOURNAL; REDUCTION; BIOSYNTHESIS; ENZYMOLOGY; GENETICS; METABOLIC ACTIVATION; METABOLISM;

ACTIVATION, METABOLIC; ESCHERICHIA COLI; GIARDIA LAMBLIA; NAD; NAD(P)H DEHYDROGENASE (QUINONE); NITRO COMPOUNDS; NITROREDUCTASES; RECOMBINANT PROTEINS;

EID: 84925967954     PISSN: None     EISSN: 22113207     Source Type: Journal    
DOI: 10.1016/j.ijpddr.2015.03.001     Document Type: Article

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