Stable expression of Escherichia coli β-glucuronidase A (GusA) in Giardia lamblia: application to high-throughput drug susceptibility testing

Journal of Antimicrobial Chemotherapy

Volumn 64, Issue 6, 2009, Pages 1187-1191

  Müller, Joachim ^a   Nillius, Dorothea ^a   Hehl, Adrian ^b   Hemphill, Andrew ^a   Müller, Norbert ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

High throughput drug screening; Reporter gene; Rransfection; Stable expression

Indexed keywords

ALBENDAZOLE; ANTIPROTOZOAL AGENT; BETA GLUCURONIDASE A; DAIDZEIN; DB 750; DINITROTOLUOL; FORMONONETIN; GENISTEIN; GLUTAMATE DEHYDROGENASE; GLYCOSIDASE; MEFLOQUINE; METRONIDAZOLE; NITAZOXANIDE; PRAZIQUANTEL; RM 4802; RM 4803; RM 4805; RM 4806; RM 4807; TIZOXANIDE; UNCLASSIFIED DRUG; BETA GLUCURONIDASE; DRUG; ESCHERICHIA COLI PROTEIN; RECOMBINANT PROTEIN; THIAZOLE DERIVATIVE;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SENSITIVITY; ESCHERICHIA COLI; GENE EXPRESSION; GIARDIA LAMBLIA; HIGH THROUGHPUT SCREENING; IC 50; NONHUMAN; PROMOTER REGION; REPORTER GENE; STRAIN DIFFERENCE; WILD TYPE; ANIMAL; BIOSYNTHESIS; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; GENETICS; METHODOLOGY; MICROBIAL VIABILITY; MICROBIOLOGICAL EXAMINATION;

ANIMALS; ANTIPROTOZOAL AGENTS; DRUG EVALUATION, PRECLINICAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENES, REPORTER; GIARDIA LAMBLIA; GLUCURONIDASE; METRONIDAZOLE; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; PHARMACEUTICAL PREPARATIONS; RECOMBINANT PROTEINS; THIAZOLES;

EID: 76249103399     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkp363     Document Type: Article

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