A novel Giardia lamblia nitroreductase, G1NR1, interacts with nitazoxanide and other thiazolides

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 6, 2007, Pages 1979-1986

  Müller, Joachim ^a   Wastling, Jonathan ^b   Sanderson, Sanya ^b   Müller, Norbert ^a   Hemphill, Andrew ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GINR1 ENZYME; NITAZOXANIDE; NITROREDUCTASE; RECOMBINANT PROTEIN; RM4802; RM4805; RM4807; RM4808; THIAZOLIDINE DERIVATIVE; TIZOXANIDE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; DRUG ACTIVITY; DRUG INHIBITION; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; ESCHERICHIA COLI; GIARDIA LAMBLIA; IN VITRO STUDY; IN VIVO STUDY; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIPARASITIC AGENTS; CHROMATOGRAPHY, AFFINITY; ENZYME INHIBITORS; GIARDIA LAMBLIA; MOLECULAR SEQUENCE DATA; NITROREDUCTASES; PARASITIC SENSITIVITY TESTS; PROTOZOAN PROTEINS; THIAZOLES;

EID: 34250160202     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.01548-06     Document Type: Article

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