Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study

Psychosomatic Medicine

Volumn 77, Issue 1, 2015, Pages 26-32

  Von Känel, Roland ^a,b,c   Malan, Nico T ^d,e   Hamer, Mark ^d,e   Malan, Leoné ^d,e  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c Clinic Barmelweid   (Switzerland)

^d NORTH WEST UNIVERSITY   (South Africa)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cardiovascular disease; Ethnicity; Genetics; Psychological stress; Telomere

Indexed keywords

C REACTIVE PROTEIN; HEMOGLOBIN A1C; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

ADULT; ALCOHOL ABUSE; ARTICLE; BLACK PERSON; BLOOD PRESSURE; BODY MASS; CAUCASIAN; CHROMOSOME STRUCTURE; DEPRESSION; DISTRESS SYNDROME; DYSLIPIDEMIA; ENERGY EXPENDITURE; ETHNIC DIFFERENCE; FEMALE; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERTENSION; JOB STRESS; LEUKOCYTE; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; MENTAL STRESS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SMOKING; SOUTH AFRICAN; SYMPATHETIC TONE; TEACHER; TELOMERE; TELOMERE LENGTH; AGED; ALCOHOLISM; HYPERGLYCEMIA; METABOLISM; MIDDLE AGED; MOTOR ACTIVITY; OBESITY; SOUTH AFRICA; TELOMERE HOMEOSTASIS; UNIVERSITY; YOUNG ADULT;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; ALCOHOLISM; C-REACTIVE PROTEIN; DEPRESSION; DYSLIPIDEMIAS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FACULTY; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HIV INFECTIONS; HUMANS; HYPERGLYCEMIA; HYPERTENSION; LEUKOCYTES; MALE; MIDDLE AGED; MOTOR ACTIVITY; OBESITY; SMOKING; SOUTH AFRICA; STRESS, PSYCHOLOGICAL; TELOMERE; TELOMERE HOMEOSTASIS; YOUNG ADULT;

EID: 84925940701     PISSN: 00333174     EISSN: 15347796     Source Type: Journal    
DOI: 10.1097/PSY.0000000000000123     Document Type: Article

References (53)

1. Blackburn EH. Telomeres and telomerase: their mechanisms of action and the effects of altering their functions. FEBS Lett 2005;579:859-62.
2. Blackburn EH. Telomere states and cell fates. Nature 2000;408:53-6.
3. Broer L, Codd V, Nyholt DR, Deelen J, ManginoM,Willemsen G, Albrecht E, Amin N, Beekman M, de Geus EJ, Henders A, Nelson CP, Steves CJ, Wright MJ, de Craen AJ, Isaacs A, Matthews M, Moayyeri A, Montgomery GW, Oostra BA, Vink JM, Spector TD, Slagboom PE,Martin NG, Samani NJ, van Duijn CM, Boomsma DI. Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. Eur J Hum Genet 2013;21:1163-8.
4. Mayer S, Brüderlein S, Perner S, Waibel I, Holdenried A, Ciloglu N, Hasel C, Mattfeldt T, Nielsen KV, Möller P. Sex-specific telomere length profiles and age-dependent erosion dynamics of individual chromosome arms in humans. Cytogenet Genome Res 2006;112:194-201.
5. Needham BL, Adler N, Gregorich S, Rehkopf D, Lin J, Blackburn EH, Epel ES. Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999-2002. Soc Sci Med 2013;85:1-8.
6. Cherkas LF, Hunkin JL, Kato BS, Richards JB, Gardner JP, Surdulescu GL, Kimura M, Lu X, Spector TD, Aviv A. The association between physical activity in leisure time and leukocyte telomere length. Arch Intern Med 2008; 168:154-8.
7. Pavanello S, Hoxha M, Dioni L, Bertazzi PA, Snenghi R, Nalesso A, Ferrara SD, Montisci M, Baccarelli A. Shortened telomeres in individuals with abuse in alcohol consumption. Int J Cancer 2011;129:983-92.
8. PhillipsAC, Robertson T, CarrollD,DerG, Shiels PG,McGlynn L,Benzeval M. Do symptoms of depression predict telomere length? Evidence from the west of Scotland Twenty-07 Study. Psychosom Med 2013;75:288-96.
9. Huzen J, van der Harst P, de Boer RA, Lesman-Leegte I, Voors AA, van Gilst WH, Samani NJ, Jaarsma T, van Veldhuisen DJ. Telomere length and psychologicalwell-being in patients with chronic heart failure. Age Ageing 2010;39:223-7.
10. Ahola K, Sirén I, KivimäkiM, Ripatti S, Aromaa A, Lönnqvist J, Hovatta I. Work-related exhaustion and telomere length: a population-based study. PLoS One 2012;7:e40186.
11. Houben JM, Moonen HJ, van Schooten FJ, Hageman GJ. Telomere length assessment: biomarker of chronic oxidative stress? Free Radic Biol Med 2008;44:235-46.
12. Brouilette SW, Moore JS, McMahon AD, Thompson JR, Ford I, Shepherd J, Packard CJ, Samani NJ; West of Scotland Coronary Prevention Study Group. Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. Lancet 2007;369:107-14.
13. Ding H, Chen C, Shaffer JR, Liu L, Xu Y, Wang X, Hui R, Wang DW. Telomere length and risk of stroke in Chinese. Stroke 2012;43:658-63.
14. Lung FW, Ku CS, Kao WT. Telomere length may be associated with hypertension. J Hum Hypertens 2008;22:230-2.
15. Lee M, Martin H, Firpo MA, Demerath EW. Inverse association between adiposity and telomere length: The Fels Longitudinal Study. Am J Hum Biol 2011;23:100-6.
16. Huzen J, Wong LS, van Veldhuisen DJ, Samani NJ, Zwinderman AH, Codd V, Cawthon RM, Benus GF, van der Horst IC, Navis G, Bakker SJ, Gansevoort RT, de Jong PE, Hillege HL, van GilstWH, de Boer RA, van der Harst P. Telomere length loss due to smoking and metabolic traits. J Intern Med 2014;275:155-63.
17. Sliwa K, Wilkinson D, Hansen C, Ntyintyane L, Tibazarwa K, Becker A, Stewart S. Spectrum of heart disease and risk factors in a black urban population in South Africa (the Heart of Soweto Study): a cohort study. Lancet 2008;371:915-22.
18. Bradshaw D, Groenewald P, Laubscher R, Nannan N, Nojilana B, Norman R, PieterseD, SchneiderM. Initial Burden of Disease Estimates for South Africa, 2000. Cape Town: South African Medical Research Council; 2003.
19. Alberts M, Urdal P, Steyn K, Stensvold I, Tverdal A, Nel JH, Steyn NP. Prevalence of cardiovascular diseases and associated risk factors in a rural black population of South Africa. Eur J Cardiovasc Prev Rehabil 2005; 12:347-54.
20. Opie LH, Seedat YK. Hypertension in sub-Saharan African populations. Circulation 2005;112:3562-8.
21. Pathai S, Lawn SD, Gilbert CE, McGuinness D, McGlynn L, Weiss HA, Port J, Christ T, Barclay K, Wood R, Bekker LG, Shiels PG. Accelerated biological ageing in HIV-infected individuals in South Africa: a casecontrol study. AIDS 2013;27:2375-84.
22. von Känel R, Hamer M, Malan NT, Scheepers K, Meiring M, Malan L. Procoagulant reactivity to laboratory acute mental stress in Africans and Caucasians, and its relation to depressive symptoms: The SABPA Study. Thromb Haemost 2013;110:977-86.
23. Boshoff SM, Potgieter JC, Ellis SM,Malan L. Validation of the Teacher Stress Inventory (TSI) in a South African context: The SABPA Study. Master-Thesis. Potchefstroom, South Africa: North-West University, Potchefstroom Campus, 2011:1-58.
24. Hunt SC, Chen W, Gardner JP, Kimura M, Srinivasan SR, Eckfeldt JH, Berenson GS, Aviv A. Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study. Aging Cell 2008;7:451-8.
25. Elbers CC, GarciaME, KimuraM, Cummings SR, Nalls MA, Newman AB, Park V, Sanders JL, Tranah GJ, Tishkoff SA, Harris TB, Aviv A. Comparison Between Southern Blots and qPCR Analysis of Leukocyte Telomere Length in the Health ABC Study. J Gerontol A Biol Sci Med Sci. 2014;69:527-31.
26. Hofmann JN, Baccarelli A, Schwartz K, Davis FG, Ruterbusch JJ, Hoxha M, McCarthy BJ, Savage SA,Wacholder S, Rothman N, Graubard BI, Colt JS, Chow WH, Purdue MP. Risk of renal cell carcinoma in relation to blood telomere length in a population-based case-control study. Br J Cancer 2011;105:1772-5.
27. Fitzpatrick AL, Kronmal RA, Kimura M, Gardner JP, Psaty BM, Jenny NS, Tracy RP, Hardikar S, Aviv A. Leukocyte telomere length and mortality in the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci 2011;66:421-9.
28. Diez Roux AV, Ranjit N, Jenny NS, Shea S, Cushman M, Fitzpatrick A, Seeman T. Race/ethnicity and telomere length in the Multi-Ethnic Study of Atherosclerosis. Aging Cell 2009;8:251-7.
29. Tishkoff SA, Reed FA, Friedlaender FR, Ehret C, Ranciaro A, Froment A, Hirbo JB, Awomoyi AA, Bodo JM, Doumbo O, Ibrahim M, Juma AT, KotzeMJ, Lema G,Moore JH, Mortensen H, Nyambo TB, Omar SA, Powell K, Pretorius GS, Smith MW, Thera MA, Wambebe C, Weber JL, Williams SM. The genetic structure and history of Africans and African Americans. Science 2009;324:1035-44.
30. World Medical Association. Declaration of Helsinki. Ethical principles of medical research involving human subjects. J Indian Med Assoc 2009;107:403-5.
31. Barna I, Keazei A, Dunai A. Evaluation of Meditech ABPM-04 ambulatory blood pressure measuring device according to the British Hypertension Society protocol. Blood Press Monit 1998;3:363-8.
32. Mancia G, Fagard R, Narkiewicz K, Redoen J, Zanchetti A, Böhm M, Christiaens T, Cifkova R, De Backer G, Dominiczak A, Galderisi M, Grobbee DE, Jaarsma T, Kirchhof P, Kjeldsen SE, Laurent S, Manolis AJ, Nilsson PM, Ruilope LM, Schmieder RE, Sirnes PA, Sleight P, Viigimaa M,Waeber B, Zannad F; Task Force Members. 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2013;31:1281-357.
33. Hastedt M, Büchner M, Rothe M, Gapert R, Herre S, Krumbiegel F, Tsokos M, Kienast T, Heinz A, Hartwig S. Detecting alcohol abuse: traditional blood alcohol markers compared to ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) measurement in hair. Forensic Sci Med Pathol 2013;9:471-7.
34. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 2001;16:606-13.
35. Goldberg DP, Hillier VF. A scaled version of the General Health Questionnaire. Psychol Med 1979;9:139-45.
36. Boyle GJ, Borg MG, Falzon JM, Baglioni AJ. A structural model of the dimensions of teacher stress. Br J Educ Psychol 1995;65:29-67.
37. Cawthon RM. Telomere measurement by quantitative PCR. Nucleic Acids Res 2002;30:e47.
38. Rehkopf DH, Dow WH, Rosero-Bixby L, Lin J, Epel ES, Blackburn EH. Longer leukocyte telomere length in Costa Rica's Nicoya Peninsula: a population-based study. Exp Gerontol 2013;48:1266-73.
39. Ladwig KH, Brockhaus AC, Baumert J, Lukaschek K, Emeny RT, Kruse J, Codd V, Häfner S, Albrecht E, Illig T, Samani NJ, Wichmann HE, Gieger C, Peters A. Posttraumatic stress disorder and not depression is associated with shorter leukocyte telomere length: findings from 3,000 participants in the population-based KORA F4 study. PLoS One 2013;8:e64762.
40. Fujishiro K, Diez-Roux AV, Landsbergis PA, Jenny NS, Seeman T. Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: the Multiethnic Study of Atherosclerosis (MESA). Occup Environ Med 2013;70:552-60.
41. von Känel R. Psychosocial stress and cardiovascular risk: current opinion. Swiss Med Wkly 2012;142:w13502.
42. RomanoGH,Harari Y,Yehuda T, PodhorzerA, Rubinstein L, Shamir R,Gottlieb A, Silberberg Y, Pe'er D, Ruppin E, Sharan R, Kupiec M. Environmental stresses disrupt telomere length homeostasis. PLoS Genet 2013;9:e1003721.
43. Brydon L, Lin J, Butcher L, Hamer M, Erusalimsky JD, Blackburn EH, Steptoe A. Hostility and cellular aging in men from the Whitehall II cohort. Biol Psychiatry 2012;71:767-73.
44. Zhu H, Wang X, Gutin B, Davis CL, Keeton D, Thomas J, Stallmann-Jorgensen I, Mooken G, Bundy V, Snieder H, van der Harst P, Dong Y. Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity. J Pediatr 2011;158:215-20.
45. Aviv A, ChenW, Gardner JP, Kimura M, Brimacombe M, Cao X, Srinivasan SR, Berenson GS. Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study. AmJ Epidemiol 2009;169:323-9.
46. Gardner JP, Li S, Srinivasan SR, Chen W, Kimura M, Lu X, Berenson GS, Aviv A. Rise in insulin resistance is associated with escalated telomere attrition. Circulation 2005;111:2171-7.
47. Malan L, Malan NT, Wissing MP, Seedat YK. Coping with urbanization: a cardiometabolic risk? The THUSA study. Biol Psychol 2008;79:323-8.
48. Willeit P,Willeit J, Brandstätter A, Ehrlenbach S, Mayr A, Gasperi A,Weger S, Oberhollenzer F, Reindl M, Kronenberg F, Kiechl S. Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk. Arterioscler Thromb Vasc Biol 2010;30:1649-56.
49. De Meyer T, Rietzschel ER, De Buyzere ML, Langlois MR, De Bacquer D, Segers P, Van Damme P, De Backer GG, Van Oostveldt P, Van CriekingeW, Gillebert TC, Bekaert S; Asklepios Study Investigators. Systemic telomere length and preclinical atherosclerosis: the Asklepios Study. Eur Heart J 2009;30:3074-81.
50. Vasan RS, Demissie S, Kimura M, Cupples LA, White C, Gardner JP, Cao X, Levy D, Benjamin EJ, Aviv A. Association of leukocyte telomere length with echocardiographic left ventricular mass: the Framingham Heart Study. Circulation 2009;120:1195-202.
51. Serrano AL, Andrés V. Telomeres and cardiovascular disease: does size matter? Circ Res 2004;94:575-84.
52. Chae DH, Nuru-Jeter AM, Adler NE, Brody GH, Lin J, Blackburn EH, Epel ES. Discrimination, racial bias, and telomere length in African-American men. Am J Prev Med 2014;46:103-11.
53. Friedrich U, Griese E, Schwab M, Fritz P, Thon K, Klotz U. Telomere length in different tissues of elderly patients. Mech Ageing Dev 2000; 119:89-99.