Discrimination, racial bias, and telomere length in African-American men

American Journal of Preventive Medicine

Volumn 46, Issue 2, 2014, Pages 103-111

  Chae, David H ^a   Nuru Jeter, Amani M ^b   Adler, Nancy E ^c   Brody, Gene H ^d   Lin, Jue ^c   Blackburn, Elizabeth H ^c   Epel, Elissa S ^c  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AFRICAN AMERICAN; AGING; ARTICLE; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; DATA ANALYSIS; HEALTH STATUS; HUMAN; INCOME; LEUKOCYTE TELOMERE LENGTH; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; POVERTY; RACISM; REGRESSION ANALYSIS; SOCIOECONOMICS; TELOMERE;

ADULT; AFRICAN AMERICANS; AGING; CROSS-SECTIONAL STUDIES; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; RACISM; TELOMERE HOMEOSTASIS;

EID: 84892541527     PISSN: 07493797     EISSN: 18732607     Source Type: Journal    
DOI: 10.1016/j.amepre.2013.10.020     Document Type: Article

References (105)

1. M.D. Hayward, and M. Heron Racial inequality in active life among adult Americans Demography 36 1999 77 91
2. R.G. Rogers, R.A. Hummer, and C.B. Nam Living and dying in the USA: behavioral, health, and social differential in adult mortality 2000 Academic Press San Diego CA
3. P.D. Sorlie, E. Backlund, and JB. Keller U.S. mortality by economic, demographic, and social characteristics: the National Longitudinal Mortality Study Am J Public Health 85 1995 949 956
4. National Center for Health Statistics. Health, U.S., 2007 with chartbook on trends in the health of Americans. Hyattsville MD, 2007.
5. A. Palloni, and D.C. Ewbank Selection processes in the study of racial and ethnic differentials in adult health and mortality N.B. Anderson, R.A. Bulatao, B. Cohen, Critical perspectives on racial and ethnic differences in health in late life 2004 National Academies Press Washington DC 171 226
6. J. Liang, X. Xu, J.M. Bennett, W. Ye, and A.R. Quinones Ethnicity and changing functional health in middle and late life: a person-centered approach J Gerontol B Psychol Sci Soc Sci 65 2010 470 481
7. R. Clark, N.B. Anderson, V.R. Clark, and D.R. Williams Racism as a stressor for African Americans. A biopsychosocial model Am Psychol 54 1999 805 816
8. V.R. Clark The perilous effects of racism on blacks Ethn Dis 11 2001 769 772
9. C.P. Jones Levels of racism: a theoretic framework and a gardener's tale Am J Public Health 90 2000 1212 1215
10. D.H. Chae, A.M. Nuru-Jeter, K.D. Lincoln, and D.D. Francis Conceptualizing racial disparities in health Du Bois Rev 8 2011 63 77
11. C.L. Broman The health consequences of racial discrimination: a study of African Americans Ethn Dis 6 1996 148 153
12. D.R. Williams, H.W. Neighbors, and J.S. Jackson Racial/ethnic discrimination and health: findings from community studies Am J Public Health 98 2008 S29 S37
13. D.R. Williams, D.A. John, D. Oyserman, J. Sonnega, S.A. Mohammed, and J.S. Jackson Research on discrimination and health: an exploratory study of unresolved conceptual and measurement issues Am J Public Health 102 2012 975 978
14. A.D. Ong, T. Fuller-Rowell, and A.L. Burrow Racial discrimination and the stress process J Pers Soc Psychol 96 2009 1259 1271
15. V.M. Mays, S.D. Cochran, and Barnes NW. Race race-based discrimination, and health outcomes among African Americans Annu Rev Psychol 58 2007 201 225
16. N. Krieger, A. Kosheleva, P.D. Waterman, J.T. Chen, and K. Koenen Racial discrimination, psychological distress, and self-rated health among U.S.-born and foreign-born black Americans Am J Public Health 101 2011 1704 1713
17. D.R. Williams, and R. Williams-Morris Racism and mental health: the African American experience Ethn Health 5 2000 243 268
18. L.N. Borrell, D.R. Jacobs Jr, D.R. Williams, M.J. Pletcher, T.K. Houston, and C.I. Kiefe Self-reported racial discrimination and substance use in the Coronary Artery Risk Development in Adults Study Am J Epidemiol 166 2007 1068 1079
19. T. Minior, S. Galea, J. Stuber, J. Ahern, and D. Ompad Racial differences in discrimination experiences and responses among minority substance users Ethn Dis 13 2003 521 527
20. J.K. Martin, S.A. Tuch, and P.M. Roman Problem drinking patterns among African Americans: the impacts of reports of discrimination, perceptions of prejudice, and "risky" coping strategies J Health Soc Behav 44 2003 408 425
21. J.P. Harrell, S. Hall, and J. Taliaferro Physiological responses to racism and discrimination: an assessment of the evidence Am J Public Health 93 2003 243 248
22. D.C. Cooper, P.J. Mills, W.A. Bardwell, M.G. Ziegler, and J.E. Dimsdale The effects of ethnic discrimination and socioeconomic status on endothelin-1 among blacks and whites Am J Hypertens 22 2009 698 704
23. T.L. Green, and W.A. Darity Jr Under the skin: using theories from biology and the social sciences to explore the mechanisms behind the black-white health gap Am J Public Health 100 S1 2010 S36 S40
24. T.T. Lewis, A.E. Aiello, S. Leurgans, J. Kelly, and L.L. Barnes Self-reported experiences of everyday discrimination are associated with elevated C-reactive protein levels in older African-American adults Brain Behav Immun 24 2010 438 443
25. D.H. Chae, A.M. Nuru-Jeter, K.D. Lincoln, and K.R. Jacob Arriola Racial discrimination, mood disorders, and cardiovascular disease among black Americans Ann Epidemiol 22 2012 104 111
26. D.H. Chae, K.D. Lincoln, N.E. Adler, and S.L. Syme Do experiences of racial discrimination predict cardiovascular disease among African American men? The moderating role of internalized negative racial group attitudes Soc Sci Med 71 2010 1182 1188
27. R.M. Sellers, and J.N. Shelton The role of racial identity in perceived racial discrimination J Pers Soc Psychol 84 2003 1079 1092
28. E.S. Tull, Y.T. Sheu, C. Butler, and K. Cornelious Relationships between perceived stress, coping behavior and cortisol secretion in women with high and low levels of internalized racism J Natl Med Assoc 97 2005 206 212
29. A. Torres, and L. Bowens Correlation between the internalization theme of racial identity attitude survey-B and systolic blood pressure Ethn Dis 10 2000 375 383
30. L.D. Scott The relation of racial identity and racial socialization to coping with discrimination among African American adolescents J Black Stud 33 2003 520 538
31. R.M. Sellers, C.H. Caldwell, K.H. Schmeelk-Cone, and M.A. Zimmerman Racial identity, racial discrimination, perceived stress, and psychological distress among African American young adults J Health Soc Behav 44 2003 302 317
32. R.T. Carter, and A.L. Reynolds Race-related stress, racial identity status attitudes, and emotional reactions of black Americans Cultur Divers Ethnic Minor Psychol 17 2011 156 162
33. T. Yip, E.K. Seaton, and R.M. Sellers African American racial identity across the lifespan: identity status, identity content, and depressive symptoms Child Dev 77 2006 1504 1517
34. T.E. Fuller-Rowell, C.D. Cogburn, A.B. Brodish, S.C. Peck, O. Malanchuk, and J.S. Eccles Racial discrimination and substance use: longitudinal associations and identity moderators J Behav Med 2011 (epub ahead of print PMID: 22113318)
35. G. Aubert, and P.M. Lansdorp Telomeres and aging Physiol Rev 88 2008 557 579
36. R.T. Calado, and N.S. Young Telomere diseases N Engl J Med 361 2009 2353 2365
37. P. Monaghan Telomeres and life histories: the long and the short of it Ann N Y Acad Sci 1206 2010 130 142
38. H. Riethman Human telomere structure and biology Annu Rev Genomics Hum Genet 9 2008 1 19
39. M. Mason, A. Schuller, and E. Skordalakes Telomerase structure function Curr Opin Struct Biol 21 2011 92 100
40. L. Kaszubowska Telomere shortening and ageing of the immune system J Physiol Pharmacol 59 S9 2008 169 186
41. C. Koppelstaetter, G. Kern, and G. Mayer Biomarkers of aging with prognostic and predictive value in non-oncological diseases Curr Med Chem 16 2009 3469 3475
42. S. Saliques, M. Zeller, and J. Lorin et al. Telomere length and cardiovascular disease Arch Cardiovasc Dis 103 2010 454 459
43. J.J. Goronzy, L. Shao, and C.M. Weyand Immune aging and rheumatoid arthritis Rheum Dis Clin North Am 36 2010 297 310
44. S. Georgin-Lavialle, A. Aouba, and L. Mouthon et al. The telomere/telomerase system in autoimmune and systemic immune-mediated diseases Autoimmun Rev 9 2010 646 651
45. A.M. Valdes, I.J. Deary, and J. Gardner et al. Leukocyte telomere length is associated with cognitive performance in healthy women Neurobiol Aging 31 2010 986 992
46. J. Huzen, R.A. de Boer, D.J. van Veldhuisen, W.H. van Gilst, and P. van der Harst The emerging role of telomere biology in cardiovascular disease Front Biosci (Landmark Ed) 15 2010 35 45
47. E.S. Epel Psychological and metabolic stress: a recipe for accelerated cellular aging? Hormones (Athens) 8 2009 7 22
48. D. Gilley, B.S. Herbert, N. Huda, H. Tanaka, and T. Reed Factors impacting human telomere homeostasis and age-related disease Mech Ageing Dev 129 2008 27 34
49. R.B. Effros Telomere/telomerase dynamics within the human immune system: effect of chronic infection and stress Exp Gerontol 46 2011 135 140
50. O.M. Wolkowitz, E.S. Epel, V.I. Reus, and S.H. Mellon Depression gets old fast: do stress and depression accelerate cell aging? Depress Anxiety 27 2010 327 338
51. O.M. Wolkowitz, S.H. Mellon, and E.S. Epel et al. Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress - preliminary findings PLoS One 6 2011 e17837
52. M.E. Bauer, C.M. Jeckel, and C. Luz The role of stress factors during aging of the immune system Ann N Y Acad Sci 1153 2009 139 152
53. J.K. Kiecolt-Glaser, J.P. Gouin, N.P. Weng, W.B. Malarkey, D.Q. Beversdorf, and R. Glaser Childhood adversity heightens the impact of later-life caregiving stress on telomere length and inflammation Psychosom Med 73 2011 16 22
54. E.S. Epel, E.H. Blackburn, and J. Lin et al. Accelerated telomere shortening in response to life stress Proc Natl Acad Sci U S A 101 2004 17312 17315
55. A. Aviv, W. Chen, and J.P. Gardner et al. Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study Am J Epidemiol 169 2009 323 329
56. A.T. Geronimus, M.T. Hicken, J.A. Pearson, S.J. Seashols, K.L. Brown, and T.D. Cruz Do U.S. black women experience stress-related accelerated biological aging? A novel theory and first population-based test of black-white differences in telomere length Hum Nat 21 2010 19 38
57. H. Zhu, X. Wang, and B. Gutin et al. Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity J Pediatr 158 2011 215 220
58. S.C. Hunt, W. Chen, and J.P. Gardner et al. Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study Aging Cell 7 2008 451 458
59. A.L. Fitzpatrick, R.A. Kronmal, and M. Kimura et al. Leukocyte telomere length and mortality in the Cardiovascular Health Study J Gerontol A Biol Sci Med Sci 66 2011 421 429
60. A.V.D. Roux, N. Ranjit, and N.S. Jenny et al. Race/ethnicity and telomere length in the Multi-Ethnic Study of Atherosclerosis Aging Cell 8 2009 251 257
61. A.T. Geronimus, M. Hicken, D. Keene, and J. Bound "Weathering" and age patterns of allostatic load scores among blacks and whites in the U.S. Am J Public Health 96 2006 826 833
62. A.G. Greenwald, D.E. McGhee, and J.L. Schwartz Measuring individual differences in implicit cognition: the implicit association test J Pers Soc Psychol 74 1998 1464 1480
63. A.G. Greenwald, T.A. Poehlman, E.L. Uhlmann, and M.R. Banaji Understanding and using the Implicit Association Test: III. Meta-analysis of predictive validity J Pers Soc Psychol 97 2009 17 41
64. B.A. Nosek, A.G. Greenwald, and M.R. Banaji Understanding and using the Implicit Association Test: II. Method variables and construct validity Pers Soc Psychol Bull 31 2005 166 180
65. T.W. McDade, S. Williams, and J.J. Snodgrass What a drop can do: dried blood spots as a minimally invasive method for integrating biomarkers into population-based research Demography 44 2007 899 925
66. R.M. Cawthon Telomere measurement by quantitative PCR Nucleic Acids Res 30 2002 e47
67. J. Lin, E. Epel, and J. Cheon et al. Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance J Immunol Methods 352 2010 71 80
68. A. O'Donovan, E. Epel, and J. Lin et al. Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder Biol Psychiatry 70 2011 465 471
69. E.S. Epel, E. Puterman, J. Lin, E. Blackburn, A. Lazaro, and W.B. Mendes Wandering minds and aging cells Clin Psychol Sci 1 2013 75 83
70. D.L. Zanet, S. Saberi, L. Oliveira, B. Sattha, I. Gadawski, and H.C. Cote Blood and dried blood spot telomere length measurement by qPCR: assay considerations PLoS One 8 2013 e57787
71. C.H. Kroenke, M.J. Pletcher, and J. Lin et al. Telomerase, telomere length, and coronary artery calcium in black and white men in the CARDIA study Atherosclerosis 220 2012 506 512
72. A.R. McConnell, and J.M. Leibold Relations among the Implicit Association Test, discriminatory behavior, and explicit measures of racial attitudes J Exp Soc Psychol 37 2001 435 442
73. I.V. Blair, J.F. Steiner, and D.L. Fairclough et al. Clinicians' implicit ethnic/racial bias and perceptions of care among black and Latino patients Ann Fam Med 11 2013 43 52
74. J. Sabin, B.A. Nosek, A. Greenwald, and F.P. Rivara Physicians' implicit and explicit attitudes about race by MD race, ethnicity, and gender J Health Care Poor Underserved 20 2009 896 913
75. W.B. Mendes, H.M. Gray, R. Mendoza-Denton, B. Major, and E.S. Epel Why egalitarianism might be good for your health: physiological thriving during stressful intergroup encounters Psychol Sci 18 2007 991 998
76. J.A. Richeson, and J.N. Shelton When prejudice does not pay: effects of interracial contact on executive function Psychol Sci 14 2003 287 290
77. J.A. Richeson, S. Trawalter, and J.N. Shelton African Americans' implicit racial attitudes and the depletion of executive function after interracial interactions Soc Cognition 23 2005 336 352
78. D.H. Chae, A.M. Nuru-Jeter, and N.E. Adler Implicit racial bias as a moderator of the association between racial discrimination and hypertension: a study of Midlife African American men Psychosom Med 74 2012 961 964
79. N. Krieger, K. Smith, D. Naishadham, C. Hartman, and E.M. Barbeau Experiences of discrimination: validity and reliability of a self-report measure for population health research on racism and health Soc Sci Med 61 2005 1576 1596
80. N. Krieger, P.D. Waterman, and A. Kosheleva et al. Exposing racial discrimination: implicit & explicit measures - the My Body, My Story study of 1005 U.S.-born black & white community health center members PLoS One 6 2011 e27636
81. U.S. Census Bureau. Poverty thresholds by size of family and number of children. www.census.gov/hhes/www/poverty/data/threshld/index.html.
82. CDC. Indicators for chronic disease surveillance MMWR Recomm Rep 53 2004 19 32
83. CDC. National Health and Nutrition Examination Survey (NHANES): Anthropometry Procedures Manual, 2007.
84. A. Gelman, J. Fagan, and A. Kiss An analysis of the New York City Police Department's "Stop-and-Frisk" policy in the context of claims of racial bias J Am Stat Assoc 102 2007 813 823
85. L. Stolzenberg, S.J. D'Alessio, and D. Eitle Race and cumulative discrimination in the prosecution of criminal defendants Race Justice 3 2013 275 299
86. S.K. Malek, B.J. Keys, S. Kumar, E. Milford, and S.G. Tullius Racial and ethnic disparities in kidney transplantation Transpl Int 24 2011 419 424
87. B.D. Smedley, A.Y. Stith, and A.R. Nelson Unequal treatment: confronting racial and ethnic disparities in health care [with CD] 2009 National Academies Press Washington DC
88. D. Pager, and H. Shepherd The sociology of discrimination: racial discrimination in employment, housing, credit, and consumer markets Annu Rev Sociol 34 2008 181 209
89. D.D. Mendez, V.K. Hogan, and J. Culhane Institutional racism and pregnancy health: using Home Mortgage Disclosure act data to develop an index for mortgage discrimination at the community level Public Health Rep 126 S3 2011 102 114
90. J. Kau, D. Keenan, and H. Munneke Racial discrimination and mortgage lending J Real Estate Finan Econ 45 2012 289 304
91. J.F. Dovidio, and S.L. Gaertner Aversive racism and selection decisions: 1989 and 1999 Psychol Sci 11 2000 315 319
92. Bertrand M, Mullainathan S. Are Emily and Greg more employable than Lakisha and Jamal? A field experiment on labor market discrimination. Cambridge: National Bureau of Economic Research, 2003. NBER Working Paper No.: 9873
93. D.R. Williams, Y. Yan, J.S. Jackson, and N.B. Anderson Racial differences in physical and mental health: socio-economic status, stress and discrimination J Health Psychol 2 1997 335 351
94. E. Heard, K.E. Whitfield, C.L. Edwards, M.A. Bruce, and B.M. Beech Mediating effects of social support on the relationship among perceived stress, depression, and hypertension in African Americans J Natl Med Assoc 103 2011 116 122
95. N.R. Branscombe, M.T. Schmitt, and R.D. Harvey Perceiving pervasive discrimination among African Americans: implications for group identification and well-being J Pers Soc Psychol 77 1999 135
96. R.W. Livingston The role of perceived negativity in the moderation of African Americans' implicit and explicit racial attitudes J Exp Soc Psychol 38 2002 405 413
97. D.H. Chae, and K.L. Walters Racial discrimination and racial identity attitudes in relation to self-rated health and physical pain and impairment among two-spirit American Indians/Alaska Natives Am J Public Health 99 S1 2009 S144 S151
98. D.H. Chae, K.D. Lincoln, and J.S. Jackson Discrimination, attribution, and racial group identification: implications for psychological distress among black Americans in the National Survey of American Life (2001-2003) Am J Orthopsychiatry 81 2011 498 506
99. H.W. Neighbors, J.S. Jackson, C. Broman, and E. Thompson Racism and the mental health of African Americans: the role of self and system blame Ethn Dis 6 1996 167 175
100. J. Crocker, and B. Major Social stigma and self-esteem: the self-protective properties of stigma Psychol Rev 96 1989 608
101. G.G. Bennett, M.M. Merritt, C.L. Edwards, and J.J. Sollers Perceived racism and affective responses to ambiguous interpersonal interactions among African American men Am Behav Sci 47 2004 963 976
102. A.R. Fischer, and C.M. Shaw African Americans' mental health and perceptions of racist discrimination: the moderating effects of racial socialization experiences and self-esteem J Couns Psychol 46 1999 395
103. P.G. Shiels, L.M. McGlynn, and A. MacIntyre et al. Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort PLoS One 6 2011 e22521
104. L.F. Cherkas, A. Aviv, and A.M. Valdes et al. The effects of social status on biological aging as measured by white-blood-cell telomere length Aging Cell 5 2006 361 365
105. N. Adler, M.S. Pantell, and A. O'Donovan et al. Educational attainment and late life telomere length in the Health, Aging and Body Composition Study Brain Behav Immun 27 2013 15 21