Annonaceous acetogenin mimic AA005 induces cancer cell death via apoptosis inducing factor through a caspase-3-independent mechanism

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Han, Bing ^a   Wang, Tong Dan ^a   Shen, Shao Ming ^a   Yu, Yun ^a   Mao, Chan ^b   Yao, Zhu Jun ^b,c   Wang, Li Shun ^a,c  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NANJING UNIVERSITY   (China)

^c Shanghai Universities   (China)

Author keywords

AIF; Annonaceous acetogenins; Cancer; RIP 1; ROS

Indexed keywords

AA 005; ACETOGENIN; ANTINEOPLASTIC AGENT; APOPTOSIS INDUCING FACTOR; BINDING PROTEIN; CAMPTOTHECIN; CASPASE 3; METHYLNITRONITROSOGUANIDINE; OLAPARIB; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG; AA005; FATTY ALCOHOL; LACTONE;

ANNONACEAE; APOPTOSIS; ARTICLE; CANCER CELL LINE; CELL DEATH; CELL NUCLEUS; CELLULAR DISTRIBUTION; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; BIOSYNTHESIS; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; TUMOR CELL LINE; U-937 CELL LINE;

ACETOGENINS; APOPTOSIS INDUCING FACTOR; CASPASE 3; CELL DEATH; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ALCOHOLS; HUMANS; LACTONES; REACTIVE OXYGEN SPECIES; U937 CELLS;

EID: 84925875717     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1133-0     Document Type: Article

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