-
1
-
-
84884594132
-
Prevalence of adult huntington's disease in the uk based on diagnoses recorded in general practice records
-
Evans SJW, Douglas I, Rawlins MD, et al.Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records.J Neurol Neurosurg Psychiatry 2013; 84(10): 1156-60
-
(2013)
J Neurol Neurosurg Psychiatry
, vol.84
, Issue.10
, pp. 1156-1160
-
-
Evans, S.J.W.1
Douglas, I.2
Rawlins, M.D.3
-
2
-
-
84892932050
-
Multisource ascertainment of huntington disease in canada: Prevalence and population at risk
-
Fisher ER, Hayden MR.Multisource ascertainment of Huntington disease in Canada: prevalence and population at risk.Mov Disord 2014; 29(1): 105-14
-
(2014)
Mov Disord
, vol.29
, Issue.1
, pp. 105-114
-
-
Fisher, E.R.1
Hayden, M.R.2
-
3
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group
-
Huntington's Disease Collaborative Research Group.A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.Cell 1993; 72(6): 971-83
-
(1993)
Cell
, vol.72
, Issue.6
, pp. 971-983
-
-
-
4
-
-
84898017417
-
Huntington disease: Natural history biomarkers and prospects for therapeutics
-
Ross CA, Aylward EH, Wild EJ, et al.Huntington disease: natural history, biomarkers and prospects for therapeutics.Nat Rev Neurol 2014; 10(4): 204-16
-
(2014)
Nat Rev Neurol
, vol.10
, Issue.4
, pp. 204-216
-
-
Ross, C.A.1
Aylward, E.H.2
Wild, E.J.3
-
5
-
-
45149107487
-
Mechanisms of neurodegeneration in huntington's disease
-
Gil J, Rego A.Mechanisms of neurodegeneration in Huntington's disease.Eur J Neurosci 2008; 27(11): 2803-20
-
(2008)
Eur J Neurosci
, vol.27
, Issue.11
, pp. 2803-2820
-
-
Gil, J.1
Rego, A.2
-
7
-
-
84904787076
-
Mutant huntingtin is present in neuronal grafts in huntington disease patients
-
Cicchetti F, Lacroix S, Cisbani G, et al.Mutant huntingtin is present in neuronal grafts in Huntington disease patients.Ann Neurol 2014; 76(1): 31-42
-
(2014)
Ann Neurol
, vol.76
, Issue.1
, pp. 31-42
-
-
Cicchetti, F.1
Lacroix, S.2
Cisbani, G.3
-
8
-
-
37349066159
-
Atrophy and degeneration in sciatic nerve of presymptomatic mice carrying the huntington's disease mutation
-
Wade A, Jacobs P, Morton AJ.Atrophy and degeneration in sciatic nerve of presymptomatic mice carrying the Huntington's disease mutation.Brain Res 2008; 1188: 61-8
-
(2008)
Brain Res
, vol.1188
, pp. 61-68
-
-
Wade, A.1
Jacobs, P.2
Morton, A.J.3
-
9
-
-
0035919701
-
Loss of huntingtin-mediated bdnf gene transcription in huntington's disease
-
Zuccato C, Ciammola A, Rigamonti D, et al.Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.Science 2001; 293(5529): 493-8
-
(2001)
Science
, vol.293
, Issue.5529
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
-
10
-
-
77951665859
-
Cargo recognition failure is responsible for inefficient autophagy in huntington's disease
-
Martinez-Vicente M, Talloczy Z, Wong E, et al.Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.Nat Neurosci 2010; 13(5): 567-76
-
(2010)
Nat Neurosci
, vol.13
, Issue.5
, pp. 567-576
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Wong, E.3
-
11
-
-
49249089029
-
A novel pathogenic pathway of immune activation detectable before clinical onset in huntington's disease
-
Björkqvist M, Wild EJ, Thiele J, et al.A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.J Exp Med 2008; 205(8): 1869-77
-
(2008)
J Exp Med
, vol.205
, Issue.8
, pp. 1869-1877
-
-
Björkqvist, M.1
Wild, E.J.2
Thiele, J.3
-
12
-
-
14044264256
-
Disturbed ca2+ signaling and apoptosis of medium spiny neurons in huntington's disease
-
Tang TS, Slow E, Lupu V, et al.Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.Proc Natl Acad Sci USA 2005; 102(7): 2602-7
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.7
, pp. 2602-2607
-
-
Tang, T.S.1
Slow, E.2
Lupu, V.3
-
13
-
-
79952004099
-
Impaired dopamine release and uptake in r6/1 huntington's disease model mice
-
Ortiz AN, Kurth BJ, Osterhaus GL, Johnson MA.Impaired dopamine release and uptake in R6/1 Huntington's disease model mice.Neurosci Lett 2011; 492(1): 11-14
-
(2011)
Neurosci Lett
, vol.492
, Issue.1
, pp. 11-14
-
-
Ortiz, A.N.1
Kurth, B.J.2
Osterhaus, G.L.3
Johnson, M.A.4
-
14
-
-
84863405511
-
Motor function and dopamine release measurements in transgenic huntington's disease model rats
-
Ortiz AN, Osterhaus GL, Lauderdale K, et al.Motor function and dopamine release measurements in transgenic Huntington's disease model rats.Brain Res 2012; 1450: 148-56
-
(2012)
Brain Res
, vol.1450
, pp. 148-156
-
-
Ortiz, A.N.1
Osterhaus, G.L.2
Lauderdale, K.3
-
15
-
-
0014934113
-
Predictive test for huntington's chorea
-
Klawans HC, Paulson GW, Barbeau A.Predictive test for Huntington's chorea.Lancet 1970; 2(7684): 1185-6
-
(1970)
Lancet
, vol.2
, Issue.7684
, pp. 1185-1186
-
-
Klawans, H.C.1
Paulson, G.W.2
Barbeau, A.3
-
16
-
-
0018816611
-
Chemical pathology of huntington's disease
-
Bird ED.Chemical pathology of Huntington's disease.Annu Rev Pharmacol Toxicol 1980; 20: 533-51
-
(1980)
Annu Rev Pharmacol Toxicol
, vol.20
, pp. 533-551
-
-
Bird, E.D.1
-
17
-
-
0018973928
-
Neurochemical alterations in huntington's chorea: A study of post-mortem brain tissue
-
Spokes EG.Neurochemical alterations in Huntington's chorea: a study of post-mortem brain tissue.Brain 1980; 103(1): 179-210
-
(1980)
Brain
, vol.103
, Issue.1
, pp. 179-210
-
-
Spokes, E.G.1
-
18
-
-
77957150631
-
Corticostriatal circuit dysfunction in huntington's disease: Intersection of glutamate dopamine and calcium
-
Miller BR, Bezprozvanny I.Corticostriatal circuit dysfunction in Huntington's disease: intersection of glutamate, dopamine and calcium.Future Neurol 2010; 5(5): 735-56
-
(2010)
Future Neurol
, vol.5
, Issue.5
, pp. 735-756
-
-
Miller, B.R.1
Bezprozvanny, I.2
-
19
-
-
84887918899
-
Dopamine imbalance in huntington's disease: A mechanism for the lack of behavioral flexibility
-
Chen JY, Wang EA, Cepeda C, Levine MS.Dopamine imbalance in Huntington's disease: a mechanism for the lack of behavioral flexibility.Front Neurosci 2013; 7: 114
-
(2013)
Front Neurosci
, vol.7
, pp. 114
-
-
Chen, J.Y.1
Wang, E.A.2
Cepeda, C.3
Levine, M.S.4
-
20
-
-
2442467014
-
The neurobiology of dopamine signaling
-
Girault JA, Greengard P.The neurobiology of dopamine signaling.Arch Neurol 2004; 61(5): 641-4
-
(2004)
Arch Neurol
, vol.61
, Issue.5
, pp. 641-644
-
-
Girault, J.A.1
Greengard, P.2
-
21
-
-
0023526285
-
Human brain d1 and d2 dopamine receptors in schizophrenia, alzheimer's, parkinson's, and huntington's diseases
-
Seeman P, Bzowej NH, Guan HC, et al.Human brain D1 and D2 dopamine receptors in schizophrenia, Alzheimer's, Parkinson's, and Huntington's diseases.Neuropsychopharmacology 1987; 1(1): 5-15
-
(1987)
Neuropsychopharmacology
, vol.1
, Issue.1
, pp. 5-15
-
-
Seeman, P.1
Bzowej, N.H.2
Guan, H.C.3
-
22
-
-
0032497504
-
Parkinson's disease: First of two parts
-
Lang A, Lozano A.Parkinson's disease: first of Two Parts.N Engl J Med 1998; 339(15): 1044-53
-
(1998)
N Engl J Med
, vol.339
, Issue.15
, pp. 1044-1053
-
-
Lang, A.1
Lozano, A.2
-
23
-
-
59349104703
-
-
Sinauer Associates, Stamford, Connecticut, USA
-
Purves D, Brannon E, Cabeza R, et al.Principles of cognitive neuroscience.Sinauer Associates, Stamford, Connecticut, USA; 2008.p.757
-
(2008)
Principles of Cognitive Neuroscience
, pp. 757
-
-
Purves, D.1
Brannon, E.2
Cabeza, R.3
-
25
-
-
39449124914
-
Substantia nigra/ventral tegmental reward prediction error disruption in psychosis
-
239
-
Murray GK, Corlett PR, Clark L, et al.Substantia nigra/ventral tegmental reward prediction error disruption in psychosis.Mol Psychiatry 2008; 13(3): 239, 267-76
-
(2008)
Mol Psychiatry
, vol.13
, Issue.3
, pp. 267-276
-
-
Murray, G.K.1
Corlett, P.R.2
Clark, L.3
-
26
-
-
84906324241
-
Role of dopamine d2 receptors in human reinforcement learning
-
Eisenegger C, Naef M, Linssen A, et al.Role of dopamine D2 receptors in human reinforcement learning.Neuropsychopharmacology 2014; 39(10): 2366-75
-
(2014)
Neuropsychopharmacology
, vol.39
, Issue.10
, pp. 2366-2375
-
-
Eisenegger, C.1
Naef, M.2
Linssen, A.3
-
27
-
-
33745595886
-
Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits
-
Levy R, Dubios B.Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits.Cereb Cortex 2006; 16(7): 916-28
-
(2006)
Cereb Cortex
, vol.16
, Issue.7
, pp. 916-928
-
-
Levy, R.1
Dubios, B.2
-
28
-
-
33847225990
-
Mesocortical dopamine modulation of executive functions: Beyond working memory
-
Floresco SB, Magyar O.Mesocortical dopamine modulation of executive functions: beyond working memory.Psychopharmacology (Berl) 2006; 188(4): 567-85
-
(2006)
Psychopharmacology (Berl
, vol.188
, Issue.4
, pp. 567-585
-
-
Floresco, S.B.1
Magyar, O.2
-
29
-
-
72049083999
-
The neural circuitry of executive functions in healthy subjects and parkinson's disease
-
Leh SE, Petrides M, Strafella AP.The neural circuitry of executive functions in healthy subjects and Parkinson's disease.Neuropsychopharmacology 2010; 35(1): 70-85
-
(2010)
Neuropsychopharmacology
, vol.35
, Issue.1
, pp. 70-85
-
-
Leh, S.E.1
Petrides, M.2
Strafella, A.P.3
-
30
-
-
84925874400
-
-
Elsevier, Amsterdam
-
Dunnett SB, Bentivoglio M, Björklund A, Hökfelt T.Handbook of chemical neuroanatomy: dopamine.Elsevier, Amsterdam; 2004.p.418
-
(2004)
Handbook of Chemical Neuroanatomy: Dopamine
, pp. 418
-
-
Dunnett, S.B.1
Bentivoglio, M.2
Björklund, A.3
Hökfelt, T.4
-
31
-
-
27744473483
-
Chemistry of the mind: Neurochemical modulation of prefrontal cortical function
-
Robbins TW.Chemistry of the mind: neurochemical modulation of prefrontal cortical function.J Comp Neurol 2005; 493(1): 140-6
-
(2005)
J Comp Neurol
, vol.493
, Issue.1
, pp. 140-146
-
-
Robbins, T.W.1
-
32
-
-
0033771336
-
Prolactin: Structure, function, and regulation of secretion
-
Freeman ME, Kanyicska B, Lerant A, Nagy G.Prolactin: structure, function, and regulation of secretion.Physiol Rev 2000; 80(4): 1523-631
-
(2000)
Physiol Rev
, vol.80
, Issue.4
, pp. 1523-1631
-
-
Freeman, M.E.1
Kanyicska, B.2
Lerant, A.3
Nagy, G.4
-
33
-
-
79952032110
-
The physiology signaling and pharmacology of dopamine receptors
-
Beaulieu J, Gainetdinov RR.The physiology, signaling, and pharmacology of dopamine receptors.Pharmacol Rev 2011; 63(1): 182-217
-
(2011)
Pharmacol Rev
, vol.63
, Issue.1
, pp. 182-217
-
-
Beaulieu, J.1
Gainetdinov, R.R.2
-
34
-
-
0033842481
-
The tonic/phasic model of dopamine system regulation and its implications for understanding alcohol and psychostimulant craving
-
Grace AA.The tonic/phasic model of dopamine system regulation and its implications for understanding alcohol and psychostimulant craving.Addiction 2000; 95(Suppl 2): 119-28
-
(2000)
Addiction
, vol.95
, pp. 119-128
-
-
Grace, A.A.1
-
35
-
-
0030294556
-
The basal ganglia: Focused selection and inhibition of competing motor programs
-
Mink JW.The basal ganglia: focused selection and inhibition of competing motor programs.Prog Neurobiol 1996; 50(4): 381-425
-
(1996)
Prog Neurobiol
, vol.50
, Issue.4
, pp. 381-425
-
-
Mink, J.W.1
-
36
-
-
34247480145
-
D1 and d2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons
-
Surmeier DJ, Ding J, Day M, et al.D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons.Trends Neurosci 2007; 30(5): 228-35
-
(2007)
Trends Neurosci
, vol.30
, Issue.5
, pp. 228-235
-
-
Surmeier, D.J.1
Ding, J.2
Day, M.3
-
37
-
-
0024450903
-
The functional anatomy of basal ganglia disorders
-
Albin RL, Young AB, Penney JB.The functional anatomy of basal ganglia disorders.Trends Neurosci 1989; 12(10): 366-75
-
(1989)
Trends Neurosci
, vol.12
, Issue.10
, pp. 366-375
-
-
Albin, R.L.1
Young, A.B.2
Penney, J.B.3
-
39
-
-
33645868624
-
Dopamine release is severely compromised in the r6/2 mouse model of huntington's disease
-
Johnson MA, Rajan V, Miller CE, Wightman RM.Dopamine release is severely compromised in the R6/2 mouse model of Huntington's disease.J Neurochem 2006; 97(3): 737-46
-
(2006)
J Neurochem
, vol.97
, Issue.3
, pp. 737-746
-
-
Johnson, M.A.1
Rajan, V.2
Miller, C.E.3
Wightman, R.M.4
-
40
-
-
0036453663
-
Evidence for dysfunction of the nigrostriatal pathway in the r6/1 line of transgenic huntington's disease mice
-
Petersén A, Puschban Z, Lotharius J, et al.Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice.Neurobiol Dis 2002; 11(1): 134-46
-
(2002)
Neurobiol Dis
, vol.11
, Issue.1
, pp. 134-146
-
-
Petersén, A.1
Puschban, Z.2
Lotharius, J.3
-
41
-
-
0015745743
-
Brain dopamine and the syndromes of parkinson and huntington clinical, morphological and neurochemical correlations
-
Bernheimer H, Birkmayer W, Hornykiewicz O, et al.Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations.J Neurol Sci 1973; 20(4): 415-55
-
(1973)
J Neurol Sci
, vol.20
, Issue.4
, pp. 415-455
-
-
Bernheimer, H.1
Birkmayer, W.2
Hornykiewicz, O.3
-
42
-
-
0023944267
-
Immunocytochemical studies on the basal ganglia and substantia nigra in parkinson's disease and huntington's chorea
-
Waters CM, Peck R, Rossor M, et al.Immunocytochemical studies on the basal ganglia and substantia nigra in Parkinson's disease and Huntington's chorea.Neuroscience 1988; 25(2): 419-38
-
(1988)
Neuroscience
, vol.25
, Issue.2
, pp. 419-438
-
-
Waters, C.M.1
Peck, R.2
Rossor, M.3
-
43
-
-
0024353643
-
A quantitative investigation of the substantia nigra in huntington's disease
-
Oyanagi K, Takeda S, Takahashi H, et al.A quantitative investigation of the substantia nigra in Huntington's disease.Ann Neurol 1989; 26(1): 13-19
-
(1989)
Ann Neurol
, vol.26
, Issue.1
, pp. 13-19
-
-
Oyanagi, K.1
Takeda, S.2
Takahashi, H.3
-
44
-
-
0142153442
-
Analysis of cellular, transgenic and human models of huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology
-
Yohrling GJ, Jiang GC, DeJohn MM, et al.Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology.Mol Brain Res 2003; 119(1): 28-36
-
(2003)
Mol Brain Res
, vol.119
, Issue.1
, pp. 28-36
-
-
Yohrling, G.J.1
Jiang, G.C.2
Dejohn, M.M.3
-
45
-
-
80052358717
-
Serotonin and dopamine striatal innervation in parkinson's disease and huntington's chorea
-
Bédard C, Wallman MJ, Pourcher E, et al.Serotonin and dopamine striatal innervation in Parkinson's disease and Huntington's chorea.Parkinsonism Relat Disord 2011; 17(8): 593-8
-
(2011)
Parkinsonism Relat Disord
, vol.17
, Issue.8
, pp. 593-598
-
-
Bédard, C.1
Wallman, M.J.2
Pourcher, E.3
-
46
-
-
0023254217
-
Tyrosine hydroxylase-like immunoreactivity is distributed in the matrix compartment of normal human and huntington's disease striatum
-
Ferrante RJ, Kowall NW.Tyrosine hydroxylase-like immunoreactivity is distributed in the matrix compartment of normal human and Huntington's disease striatum.Brain Res 1987; 416(1): 141-6
-
(1987)
Brain Res
, vol.416
, Issue.1
, pp. 141-146
-
-
Ferrante, R.J.1
Kowall, N.W.2
-
47
-
-
0034624921
-
Decreased striatal monoaminergic terminals in huntington disease
-
Bohnen NI, Koeppe RA, Meyer P, et al.Decreased striatal monoaminergic terminals in Huntington disease.Neurology 2000; 54(9): 1753-9
-
(2000)
Neurology
, vol.54
, Issue.9
, pp. 1753-1759
-
-
Bohnen, N.I.1
Koeppe, R.A.2
Meyer, P.3
-
48
-
-
0035885487
-
Vesicular neurotransmitter transporters in huntington's disease: Initial observations and comparison with traditional synaptic markers
-
Suzuki M, Desmond TJ, Albin RL, Frey KA.Vesicular neurotransmitter transporters in Huntington's disease: initial observations and comparison with traditional synaptic markers.Synapse 2001; 41(4): 329-36
-
(2001)
Synapse
, vol.41
, Issue.4
, pp. 329-336
-
-
Suzuki, M.1
Desmond, T.J.2
Albin, R.L.3
Frey, K.A.4
-
49
-
-
0141591462
-
Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal gabaergic neurons
-
Cyr M, Beaulieu JM, Laakso A, et al.Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons.Proc Natl Acad Sci USA 2003; 100(19): 11035-40
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.19
, pp. 11035-11040
-
-
Cyr, M.1
Beaulieu, J.M.2
Laakso, A.3
-
50
-
-
1242316257
-
Bimodal induction of dopamine-mediated striatal neurotoxicity is mediated through both activation of d1 dopamine receptors and autoxidation
-
Wersinger C, Chen J, Sidhu A.Bimodal induction of dopamine-mediated striatal neurotoxicity is mediated through both activation of D1 dopamine receptors and autoxidation.Mol Cell Neurosci 2004; 25(1): 124-37
-
(2004)
Mol Cell Neurosci
, vol.25
, Issue.1
, pp. 124-137
-
-
Wersinger, C.1
Chen, J.2
Sidhu, A.3
-
51
-
-
43049085555
-
Dopamine determines the vulnerability of striatal neurons to the n-Terminal fragment of mutant huntingtin through the regulation of mitochondrial complex ii
-
Benchoua A, Trioulier Y, Diguet E, et al.Dopamine determines the vulnerability of striatal neurons to the N-Terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II.Hum Mol Genet 2008; 17(10): 1446-56
-
(2008)
Hum Mol Genet
, vol.17
, Issue.10
, pp. 1446-1456
-
-
Benchoua, A.1
Trioulier, Y.2
Diguet, E.3
-
52
-
-
34547411294
-
Dopaminergic signaling and striatal neurodegeneration in huntington's disease
-
Tang TS, Chen X, Liu J, Bezprozvanny I.Dopaminergic signaling and striatal neurodegeneration in Huntington's disease.J Neurosci 2007; 27(30): 7899-910
-
(2007)
J Neurosci
, vol.27
, Issue.30
, pp. 7899-7910
-
-
Tang, T.S.1
Chen, X.2
Liu, J.3
Bezprozvanny, I.4
-
53
-
-
0030897476
-
Pet study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in huntington's disease
-
Ginovart N, Lundin A, Farde L, et al.PET study of the pre- And post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease.Brain 1997; 120(Pt 3): 503-14
-
(1997)
Brain
, vol.120
, pp. 503-514
-
-
Ginovart, N.1
Lundin, A.2
Farde, L.3
-
54
-
-
73049110382
-
Cortical dopamine dysfunction in symptomatic and premanifest huntington's disease gene carriers
-
Pavese N, Politis M, Tai Y, et al.Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers.Neurobiol Dis 2010; 37(2): 356-61
-
(2010)
Neurobiol Dis
, vol.37
, Issue.2
, pp. 356-361
-
-
Pavese, N.1
Politis, M.2
Tai, Y.3
-
55
-
-
58349088376
-
Changes in striatal dopamine d2 receptor binding in pre-clinical huntington's disease
-
van Oostrom JCH, Dekker M, Willemsen TM, et al.Changes in striatal dopamine D2 receptor binding in pre-clinical Huntington's disease.Eur J Neurol 2009; 16(2): 226-31
-
(2009)
Eur J Neurol
, vol.16
, Issue.2
, pp. 226-231
-
-
Van Oostrom, J.C.H.1
Dekker, M.2
Willemsen, T.M.3
-
56
-
-
0037408213
-
Progressive striatal and cortical dopamine receptor dysfunction in huntington's disease: A pet study
-
Pavese N, Andrews T, Brooks D, et al.Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.Brain 2003; 126(5): 1127-35
-
(2003)
Brain
, vol.126
, Issue.5
, pp. 1127-1135
-
-
Pavese, N.1
Andrews, T.2
Brooks, D.3
-
57
-
-
0028978124
-
1 and d 2 receptor binding in patients with huntington's disease and other choreas a pet study
-
Turjanski N, Weeks R, Dolan R, et al.1 and D 2 receptor binding in patients with Huntington's disease and other choreas A PET study.Brain 1995; 118(3): 689-96
-
(1995)
Brain
, vol.118
, Issue.3
, pp. 689-696
-
-
Turjanski, N.1
Weeks, R.2
Dolan, R.3
-
58
-
-
0032747164
-
Huntington's disease progression pet and clinical observations
-
Andrews TC, Weeks RA, Turjanski N, et al.Huntington's disease progression.PET and clinical observations.Brain 1999; 122(Pt 1): 2353-63
-
(1999)
Brain
, vol.122
, pp. 2353-2363
-
-
Andrews, T.C.1
Weeks, R.A.2
Turjanski, N.3
-
59
-
-
2642666489
-
Cognitive deficits in huntington's disease are predicted by dopaminergic pet markers and brain volumes
-
Backman L.Cognitive deficits in Huntington's disease are predicted by dopaminergic PET markers and brain volumes.Brain 1997; 120(12): 2207-17
-
(1997)
Brain
, vol.120
, Issue.12
, pp. 2207-2217
-
-
Backman, L.1
-
60
-
-
48249114740
-
Detection of huntington's disease decades before diagnosis: The predict-hd study
-
Paulsen JS, Langbehn DR, Stout JC, et al.Detection of Huntington's disease decades before diagnosis: the Predict-HD study.J Neurol Neurosurg Psychiatry 2008; 79(8): 874-80
-
(2008)
J Neurol Neurosurg Psychiatry
, vol.79
, Issue.8
, pp. 874-880
-
-
Paulsen, J.S.1
Langbehn, D.R.2
Stout, J.C.3
-
61
-
-
0034081681
-
The pattern of neurodegeneration in huntington's disease: A comparative study of cannabinoid, dopamine, adenosine and gabaa receptor alterations in the human basal ganglia in huntington's disease
-
Glass M, Dragunow M, Faull RLM.The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABAA receptor alterations in the human basal ganglia in Huntington's disease.Neuroscience 2000; 97(3): 505-19
-
(2000)
Neuroscience
, vol.97
, Issue.3
, pp. 505-519
-
-
Glass, M.1
Dragunow, M.2
Faull, R.L.M.3
-
62
-
-
55749087155
-
Hypothalamic involvement in huntington's disease: An in vivo pet study
-
Politis M, Pavese N, Tai YF, et al.Hypothalamic involvement in Huntington's disease: an in vivo PET study.Brain 2008; 131(Pt 11): 2860-9
-
(2008)
Brain
, vol.131
, pp. 2860-2869
-
-
Politis, M.1
Pavese, N.2
Tai, Y.F.3
-
63
-
-
2642666489
-
Cognitive deficits in huntington's disease are predicted by dopaminergic pet markers and brain volumes
-
Ba L, Lundin A, Ginovart N, Farde L.Cognitive deficits in Huntington's disease are predicted by dopaminergic PET markers and brain volumes.Brain 1997; 120: 2207-17
-
(1997)
Brain
, vol.120
, pp. 2207-2217
-
-
Ba, L.1
Lundin, A.2
Ginovart, N.3
Farde, L.4
-
64
-
-
80052670073
-
Extrastriatal dopamine d(2) receptor binding in huntington's disease
-
Esmaeilzadeh M, Farde L, Karlsson P, et al.Extrastriatal dopamine D(2) receptor binding in Huntington's disease.Hum Brain Mapp 2011; 32(10): 1626-36
-
(2011)
Hum Brain Mapp
, vol.32
, Issue.10
, pp. 1626-1636
-
-
Esmaeilzadeh, M.1
Farde, L.2
Karlsson, P.3
-
65
-
-
16044373842
-
Exon 1 of the hd gene with an expanded cag repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L, Sathasivam K, Seller M, et al.Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.Cell 1996; 87(3): 493-506
-
(1996)
Cell
, vol.87
, Issue.3
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
-
66
-
-
84898657803
-
Characterization of striatal neuronal loss and atrophy in the r6/2 mouse model of huntington's disease
-
Dodds L, Chen J, Berggren K, Fox J.Characterization of striatal neuronal loss and atrophy in the R6/2 mouse model of Huntington's disease.PLoS Curr 2014; 6
-
(2014)
PLoS Curr
, pp. 6
-
-
Dodds, L.1
Chen, J.2
Berggren, K.3
Fox, J.4
-
68
-
-
0033587760
-
Transgenic mice expressing a huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity
-
Hansson O, Petersén A, Leist M, et al.Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity.Proc Natl Acad Sci USA 1999; 96(15): 8727-32
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.15
, pp. 8727-8732
-
-
Hansson, O.1
Petersén, A.2
Leist, M.3
-
69
-
-
10744227174
-
Selective striatal neuronal loss in a yac128 mouse model of huntington disease
-
Slow EJ, van Raamsdonk J, Rogers D, et al.Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.Hum Mol Genet 2003; 12(13): 1555-67
-
(2003)
Hum Mol Genet
, vol.12
, Issue.13
, pp. 1555-1567
-
-
Slow, E.J.1
Van Raamsdonk, J.2
Rogers, D.3
-
70
-
-
84860483495
-
Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of huntington disease in the full-length bachd and yac128 mice
-
Pouladi MA, Stanek LM, Xie Y, et al.Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice.Hum Mol Genet 2012; 21(10): 2219-32
-
(2012)
Hum Mol Genet
, vol.21
, Issue.10
, pp. 2219-2232
-
-
Pouladi, M.A.1
Stanek, L.M.2
Xie, Y.3
-
71
-
-
46749157501
-
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in bachd mice
-
Gray M, Shirasaki DI, Cepeda C, et al.Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.J Neurosci 2008; 28(24): 6182-95
-
(2008)
J Neurosci
, vol.28
, Issue.24
, pp. 6182-6195
-
-
Gray, M.1
Shirasaki, D.I.2
Cepeda, C.3
-
72
-
-
0032568517
-
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
-
Cha JH, Kosinski CM, Kerner JA, et al.Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene.Proc Natl Acad Sci USA 1998; 95(11): 6480-5
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.11
, pp. 6480-6485
-
-
Cha, J.H.1
Kosinski, C.M.2
Kerner, J.A.3
-
73
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the hd mutation
-
Davies SW, Turmaine M, Cozens BA, et al.Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.Cell 1997; 90(3): 537-48
-
(1997)
Cell
, vol.90
, Issue.3
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
-
74
-
-
79551655290
-
Huntington's disease: Can mice lead the way to treatment?
-
Crook ZR, Housman D.Huntington's disease: can mice lead the way to treatment?.Neuron 2011; 69(3): 423-35
-
(2011)
Neuron
, vol.69
, Issue.3
, pp. 423-435
-
-
Crook, Z.R.1
Housman, D.2
-
75
-
-
0026513174
-
Increased cerebrospinal fluid dopamine and 3, 4-dihydroxyphenylacetic acid levels in huntington's disease: Evidence for an overactive dopaminergic brain transmission
-
Garrett MC, Soares-da-Silva P.Increased cerebrospinal fluid dopamine and 3, 4-dihydroxyphenylacetic acid levels in Huntington's disease: evidence for an overactive dopaminergic brain transmission.J Neurochem 1992; 58(1): 101-6
-
(1992)
J Neurochem
, vol.58
, Issue.1
, pp. 101-106
-
-
Garrett, M.C.1
Soares-Da-Silva, P.2
-
76
-
-
80055002896
-
In vivo dopamine efflux is decreased in striatum of both fragment (r6/2) and full-length (yac128) transgenic mouse models of huntington's disease
-
Callahan JW, Abercrombie ED.In vivo dopamine efflux is decreased in striatum of both fragment (R6/2) and full-length (YAC128) transgenic mouse models of Huntington's Disease.Front Syst Neurosci 2011; 5: 61
-
(2011)
Front Syst Neurosci
, vol.5
, pp. 61
-
-
Callahan, J.W.1
Abercrombie, E.D.2
-
77
-
-
0036074718
-
The role of dopamine in motor symptoms in the r6/2 transgenic mouse model of huntington's disease
-
Hickey MA, Reynolds GP, Morton AJ.The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease.J Neurochem 2002; 81(1): 46-59
-
(2002)
J Neurochem
, vol.81
, Issue.1
, pp. 46-59
-
-
Hickey, M.A.1
Reynolds, G.P.2
Morton, A.J.3
-
78
-
-
79951974420
-
Tetrabenazine: The first approved drug for the treatment of chorea in us patients with huntington disease
-
Frank S.Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease.Neuropsychiatr Dis Treat 2010; 6: 657-65
-
(2010)
Neuropsychiatr Dis Treat
, vol.6
, pp. 657-665
-
-
Frank, S.1
-
79
-
-
84863825952
-
Tetrabenazine for the treatment of hyperkinetic movement disorders: A review of the literature
-
Chen JJ, Ondo WG, Dashtipour K, Swope DM.Tetrabenazine for the treatment of hyperkinetic movement disorders: a review of the literature.Clin Ther 2012; 34(7): 1487-504
-
(2012)
Clin Ther
, vol.34
, Issue.7
, pp. 1487-1504
-
-
Chen, J.J.1
Ondo, W.G.2
Dashtipour, K.3
Swope, D.M.4
-
80
-
-
0017045321
-
Neurochemical changes following the administration of depleters of biogenic monoamines
-
Lane JD, Smith JE, Shea PA, McBride WJ.Neurochemical changes following the administration of depleters of biogenic monoamines.Life Sci 1976; 19(11): 1663-7
-
(1976)
Life Sci
, vol.19
, Issue.11
, pp. 1663-1667
-
-
Lane, J.D.1
Smith, J.E.2
Shea, P.A.3
McBride, W.J.4
-
81
-
-
0023945855
-
Depletion of monoamine transmitters by tetrabenazine in brain tissue in huntington's disease
-
Pearson S, Reynolds G.Depletion of monoamine transmitters by tetrabenazine in brain tissue in Huntington's disease.Neuropharmacology 1988; 27(7): 717-19
-
(1988)
Neuropharmacology
, vol.27
, Issue.7
, pp. 717-719
-
-
Pearson, S.1
Reynolds, G.2
-
82
-
-
0029896966
-
Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter
-
Erickson JD, Schafer MK, Bonner TI, et al.Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter.Proc Natl Acad Sci USA 1996; 93(10): 5166-71
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.10
, pp. 5166-5171
-
-
Erickson, J.D.1
Schafer, M.K.2
Bonner, T.I.3
-
83
-
-
0023236626
-
Concentration-effect relationships of tetrabenazine and dihydrotetrabenazine in the rat
-
Mehvar R, Jamali F.Concentration-effect relationships of tetrabenazine and dihydrotetrabenazine in the rat.J Pharm Sci 1987; 76(6): 461-5
-
(1987)
J Pharm Sci
, vol.76
, Issue.6
, pp. 461-465
-
-
Mehvar, R.1
Jamali, F.2
-
84
-
-
0023833860
-
Tetrabenazine therapy of dystonia, chorea, tics, and other dyskinesias
-
Jankovic J, Orman J.Tetrabenazine therapy of dystonia, chorea, tics, and other dyskinesias.Neurology 1988; 38(3): 391-4
-
(1988)
Neurology
, vol.38
, Issue.3
, pp. 391-394
-
-
Jankovic, J.1
Orman, J.2
-
85
-
-
0031029072
-
Long-Term effects of tetrabenazine in hyperkinetic movement disorders
-
Jankovic J, Beach J.Long-Term effects of tetrabenazine in hyperkinetic movement disorders.Neurology 1997; 48(2): 358-62
-
(1997)
Neurology
, vol.48
, Issue.2
, pp. 358-362
-
-
Jankovic, J.1
Beach, J.2
-
86
-
-
33645798913
-
Tetrabenazine as antichorea therapy in huntington disease: A randomized controlled trial
-
Group HS.Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial.Neurology 2006.66(3): 366-72
-
(2006)
Neurology
, vol.66
, Issue.3
, pp. 366-372
-
-
Group, H.S.1
-
87
-
-
0017161920
-
Tetrabenazine in the treatment of huntington's chorea
-
Huang CY, McLeod JG, Holland RT, Elliot C.Tetrabenazine in the treatment of Huntington's chorea.Med J Aust 1976; 1(16): 583-4
-
(1976)
Med J Aust
, vol.1
, Issue.16
, pp. 583-584
-
-
Huang, C.Y.1
McLeod, J.G.2
Holland, R.T.3
Elliot, C.4
-
88
-
-
0017909601
-
Tetrabenazine in the treatment of huntington's chorea and other hyperkinetic movement disorders
-
Toglia JU, McGlamery M, Sambandham RR.Tetrabenazine in the treatment of Huntington's chorea and other hyperkinetic movement disorders.J Clin Psychiatry 1978; 39(1): 81-7
-
(1978)
J Clin Psychiatry
, vol.39
, Issue.1
, pp. 81-87
-
-
Toglia, J.U.1
McGlamery, M.2
Sambandham, R.R.3
-
89
-
-
0036869757
-
Tetrabenazine treatment for huntington's disease-Associated chorea
-
Ondo WG, Tintner R, Thomas M, Jankovic J.Tetrabenazine treatment for Huntington's disease-Associated chorea.Clin Neuropharmacol 2002; 25(6): 300-2
-
(2002)
Clin Neuropharmacol
, vol.25
, Issue.6
, pp. 300-302
-
-
Ondo, W.G.1
Tintner, R.2
Thomas, M.3
Jankovic, J.4
-
90
-
-
33847694844
-
Short-Term effects of tetrabenazine on chorea associated with huntington's disease
-
Kenney C, Hunter C, Davidson A, Jankovic J.Short-Term effects of tetrabenazine on chorea associated with Huntington's disease.Mov Disord 2007; 22(1): 10-13
-
(2007)
Mov Disord
, vol.22
, Issue.1
, pp. 10-13
-
-
Kenney, C.1
Hunter, C.2
Davidson, A.3
Jankovic, J.4
-
91
-
-
59849086625
-
The long-Term effect of tetrabenazine in the management of huntington disease
-
Fasano A, Cadeddu F, Guidubaldi A, et al.The long-Term effect of tetrabenazine in the management of Huntington disease.Clin Neuropharmacol 2008; 31(6): 313-18
-
(2008)
Clin Neuropharmacol
, vol.31
, Issue.6
, pp. 313-318
-
-
Fasano, A.1
Cadeddu, F.2
Guidubaldi, A.3
-
92
-
-
74549128476
-
Tetrabenazine as anti-chorea therapy in huntington disease: An open-label continuation study
-
Huntington Study Group/TETRA-HD Investigators
-
Frank S.Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study.Huntington Study Group/TETRA-HD Investigators.BMC Neurol 2009; 9: 62
-
(2009)
BMC Neurol
, vol.9
, pp. 62
-
-
Frank, S.1
-
93
-
-
41249090997
-
A study of chorea after tetrabenazine withdrawal in patients with huntington disease
-
Frank S, Ondo W, Fahn S, et al.A study of chorea after tetrabenazine withdrawal in patients with Huntington disease.Clin Neuropharmacol 2008; 31(3): 127-33
-
(2008)
Clin Neuropharmacol
, vol.31
, Issue.3
, pp. 127-133
-
-
Frank, S.1
Ondo, W.2
Fahn, S.3
-
95
-
-
0021966828
-
The gait abnormality of huntington's disease
-
Koller W, Trimble J.The gait abnormality of Huntington's disease.Neurology 1985; 35(10): 1450-4
-
(1985)
Neurology
, vol.35
, Issue.10
, pp. 1450-1454
-
-
Koller, W.1
Trimble, J.2
-
96
-
-
36549014791
-
Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo
-
Charvin D, Roze E, Perrin V, et al.Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo.Neurobiol Dis 2008; 29(1): 22-9
-
(2008)
Neurobiol Dis
, vol.29
, Issue.1
, pp. 22-29
-
-
Charvin, D.1
Roze, E.2
Perrin, V.3
-
97
-
-
24744434920
-
Unraveling a role for dopamine in huntington's disease: The dual role of reactive oxygen species and d2 receptor stimulation
-
Charvin D, Vanhoutte P, Pagès C, et al.Unraveling a role for dopamine in Huntington's disease: the dual role of reactive oxygen species and D2 receptor stimulation.Proc Natl Acad Sci USA 2005; 102(34): 12218-23
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.34
, pp. 12218-12223
-
-
Charvin, D.1
Vanhoutte, P.2
Pagès, C.3
-
98
-
-
0021222945
-
Effect of neuroleptic treatment on involuntary movements and motor performances in huntington's disease
-
Girotti F, Carella F, Scigliano G, et al.Effect of neuroleptic treatment on involuntary movements and motor performances in Huntington's disease.J Neurol Neurosurg Psychiatry 1984; 47(8): 848-52
-
(1984)
J Neurol Neurosurg Psychiatry
, vol.47
, Issue.8
, pp. 848-852
-
-
Girotti, F.1
Carella, F.2
Scigliano, G.3
-
99
-
-
0014169622
-
Drug treatment in Cases of Huntington's disease with special reference to fluphenazine (Prolixin
-
Korenyi C, Whittier JR.Drug treatment in cases of Huntington's disease with special reference to fluphenazine (Prolixin).Psychiatr Q 1967; 41(2): 203-10
-
(1967)
Psychiatr Q
, vol.41
, Issue.2
, pp. 203-210
-
-
Korenyi, C.1
Whittier, J.R.2
-
100
-
-
0021175970
-
A double blind trial of sulpiride in huntington's disease and tardive dyskinesia
-
Quinn N, Marsden CD.A double blind trial of sulpiride in Huntington's disease and tardive dyskinesia.J Neurol Neurosurg Psychiatry 1984; 47(8): 844-7
-
(1984)
J Neurol Neurosurg Psychiatry
, vol.47
, Issue.8
, pp. 844-847
-
-
Quinn, N.1
Marsden, C.D.2
-
101
-
-
57049139342
-
A europe-wide assessment of current medication choices in huntington's disease
-
Priller J, Ecker D, Landwehrmeyer B, Craufurd D.A Europe-wide assessment of current medication choices in Huntington's disease.Mov Disord 2008; 23(12): 1788
-
(2008)
Mov Disord
, vol.23
, Issue.12
, pp. 1788
-
-
Priller, J.1
Ecker, D.2
Landwehrmeyer, B.3
Craufurd, D.4
-
105
-
-
0029936269
-
A comparative trial use of sulpiride and risperidone in huntington's disease: A pilot study
-
Reveley MA, Dursun SM, Andrews H.A comparative trial use of sulpiride and risperidone in Huntington's disease: a pilot study.J Psychopharmacol 1996; 10(2): 162-5
-
(1996)
J Psychopharmacol
, vol.10
, Issue.2
, pp. 162-165
-
-
Reveley, M.A.1
Dursun, S.M.2
Andrews, H.3
-
106
-
-
39749165003
-
Risperidone and the treatment of psychiatric, motor, and cognitive symptoms in huntington's disease
-
Duff K, Beglinger LJ, O'Rourke ME, et al.Risperidone and the treatment of psychiatric, motor, and cognitive symptoms in Huntington's disease.Ann Clin Psychiatry 2008; 20(1): 1-3
-
(2008)
Ann Clin Psychiatry
, vol.20
, Issue.1
, pp. 1-3
-
-
Duff, K.1
Beglinger, L.J.2
O'rourke, M.E.3
-
107
-
-
0042887023
-
Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology
-
Shapiro DA, Renock S, Arrington E, et al.Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology.Neuropsychopharmacology 2003; 28(8): 1400-11
-
(2003)
Neuropsychopharmacology
, vol.28
, Issue.8
, pp. 1400-1411
-
-
Shapiro, D.A.1
Renock, S.2
Arrington, E.3
-
108
-
-
61449249292
-
Treatment of the symptoms of huntington's disease: Preliminary results comparing aripiprazole and tetrabenazine
-
Brusa L, Orlacchio A, Moschella V, et al.Treatment of the symptoms of Huntington's disease: preliminary results comparing aripiprazole and tetrabenazine.Mov Disord 2009; 24(1): 126-9
-
(2009)
Mov Disord
, vol.24
, Issue.1
, pp. 126-129
-
-
Brusa, L.1
Orlacchio, A.2
Moschella, V.3
-
109
-
-
70449710919
-
Aripiprazole in the treatment of huntington's disease: A case series
-
Ciammola A, Sassone J, Colciago C, et al.Aripiprazole in the treatment of Huntington's disease: a case series.Neuropsychiatr Dis Treat 2009; 5: 1-4
-
(2009)
Neuropsychiatr Dis Treat
, vol.5
, pp. 1-4
-
-
Ciammola, A.1
Sassone, J.2
Colciago, C.3
-
110
-
-
77955054223
-
Bromocriptine, an ergot alkaloid, inhibits excitatory amino acid release mediated by glutamate transporter reversal
-
Shirasaki Y, Sugimura M, Sato T.Bromocriptine, an ergot alkaloid, inhibits excitatory amino acid release mediated by glutamate transporter reversal.Eur J Pharmacol 2010; 643(1): 48-57
-
(2010)
Eur J Pharmacol
, vol.643
, Issue.1
, pp. 48-57
-
-
Shirasaki, Y.1
Sugimura, M.2
Sato, T.3
-
111
-
-
0017136319
-
Effects of bromocriptine on central dopaminergic receptors
-
Trabucchi M, Spano PF, Tonon GC, Frattola L.Effects of bromocriptine on central dopaminergic receptors.Life Sci 1976; 19(2): 225-31
-
(1976)
Life Sci
, vol.19
, Issue.2
, pp. 225-231
-
-
Trabucchi, M.1
Spano, P.F.2
Tonon, G.C.3
Frattola, L.4
-
113
-
-
0019307361
-
Effects of da agonist in huntington disease hyperkinesia
-
Caraceni TA, Girotti F, Giovannini P, et al. Effects of da Agonist in Huntington Disease Hyperkinesia.Ital J Neurol Sci 1980; 1(3): 155-61
-
(1980)
Ital J Neurol Sci
, vol.1
, Issue.3
, pp. 155-161
-
-
Caraceni, T.A.1
Girotti, F.2
Giovannini, P.3
-
114
-
-
0020612106
-
Acute treatment of huntington's chorea with lisuride
-
Frattola L, Albizzati MG, Alemani A, et al.Acute treatment of Huntington's chorea with lisuride.J Neurol Sci 1983; 59(2): 247-53
-
(1983)
J Neurol Sci
, vol.59
, Issue.2
, pp. 247-253
-
-
Frattola, L.1
Albizzati, M.G.2
Alemani, A.3
-
116
-
-
0016382903
-
Letter: Huntington's chorea and levodopa
-
Schenk G, Leijnse-Ybema HJ.Letter: Huntington's chorea and levodopa.Lancet 1974; 1(7853): 364
-
(1974)
Lancet
, vol.1
, Issue.7853
, pp. 364
-
-
Schenk, G.1
Leijnse-Ybema, H.J.2
-
118
-
-
67649304952
-
Emerging drug therapies in huntington's disease
-
Mason SL, Barker RA.Emerging drug therapies in Huntington's disease.Expert Opin Emerg Drugs 2009; 14(2): 273-97
-
(2009)
Expert Opin Emerg Drugs
, vol.14
, Issue.2
, pp. 273-297
-
-
Mason, S.L.1
Barker, R.A.2
-
119
-
-
0034057350
-
Late onset levodopa responsive huntington's disease with minimal chorea masquerading as parkinson plus syndrome
-
Reuter I, Hu MT, Andrews TC, et al.Late onset levodopa responsive Huntington's disease with minimal chorea masquerading as Parkinson plus syndrome.J Neurol Neurosurg Psychiatry 2000; 68(2): 238-41
-
(2000)
J Neurol Neurosurg Psychiatry
, vol.68
, Issue.2
, pp. 238-241
-
-
Reuter, I.1
Hu, M.T.2
Andrews, T.C.3
-
120
-
-
77955772400
-
In vivo pharmacology of the dopaminergic stabilizer pridopidine
-
Ponten H, Kullingsjö J, Lagerkvist S, et al.In vivo pharmacology of the dopaminergic stabilizer pridopidine.Eur J Pharmacol 2010; 644(1-3): 88-95
-
(2010)
Eur J Pharmacol
, vol.644
, Issue.1-3
, pp. 88-95
-
-
Ponten, H.1
Kullingsjö, J.2
Lagerkvist, S.3
-
121
-
-
33745933839
-
The dopamine stabilizers (s)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-osu6162] and 4-(3-methanesulfonylphenyl)-1-propyl-piperidine (acr16) show high in vivo d2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in the rat
-
Natesan S, Svensson KA, Reckless GE, et al.The dopamine stabilizers (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-OSU6162] and 4-(3-methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in the rat.J Pharmacol Exp Ther 2006; 318(2): 810-18
-
(2006)
J Pharmacol Exp Ther
, vol.318
, Issue.2
, pp. 810-818
-
-
Natesan, S.1
Svensson, K.A.2
Reckless, G.E.3
-
122
-
-
1242329383
-
Schizophrenia: From dopamine to glutamate and back
-
Carlsson ML, Carlsson A, Nilsson M.Schizophrenia: from dopamine to glutamate and back.Curr Med Chem 2004; 11(3): 267-77
-
(2004)
Curr Med Chem
, vol.11
, Issue.3
, pp. 267-277
-
-
Carlsson, M.L.1
Carlsson, A.2
Nilsson, M.3
-
123
-
-
77957986360
-
Efficacy and safety of the dopaminergic stabilizer pridopidine (acr16) in patients with huntington's disease
-
Lundin A, Dietrichs E, Haghighi S, et al.Efficacy and safety of the dopaminergic stabilizer Pridopidine (ACR16) in patients with Huntington's disease.Clin Neuropharmacol 2010; 33(5): 260-4
-
(2010)
Clin Neuropharmacol
, vol.33
, Issue.5
, pp. 260-264
-
-
Lundin, A.1
Dietrichs, E.2
Haghighi, S.3
-
124
-
-
81255195330
-
Pridopidine for the treatment of motor function in patients with huntington's disease (mermaihd): A phase 3 randomised double-blind placebo-controlled trial
-
de Yebenes JG, Landwehrmeyer B, Squitieri F, et al.Pridopidine for the treatment of motor function in patients with Huntington's disease (MermaiHD): a phase 3, randomised, double-blind, placebo-controlled trial.Lancet Neurol 2011; 10(12): 1049-57
-
(2011)
Lancet Neurol
, vol.10
, Issue.12
, pp. 1049-1057
-
-
De Yebenes, J.G.1
Landwehrmeyer, B.2
Squitieri, F.3
-
125
-
-
84884724757
-
A randomized, double-blind, placebo-controlled trial of pridopidine in huntington's disease
-
Huntington Study Group HART Investigators
-
Huntington Study Group HART Investigators.A randomized, double-blind, placebo-controlled trial of pridopidine in Huntington's disease.Mov Disord 2013; 28(10): 1407-15
-
(2013)
Mov Disord
, vol.28
, Issue.10
, pp. 1407-1415
-
-
-
126
-
-
84871295100
-
The dopamine stabilizers acr16 and (-)-osu6162 display nanomolar affinities at the s-1 receptor
-
Sahlholm K, Århem P, Fuxe K, Marcellino D.The dopamine stabilizers.ACR16 and (-)-OSU6162 display nanomolar affinities at the s-1 receptor.Mol Psychiatry 2013; 18(1): 12-14
-
(2013)
Mol Psychiatry
, vol.18
, Issue.1
, pp. 12-14
-
-
Sahlholm, K.1
Århem, P.2
Fuxe, K.3
Marcellino, D.4
-
127
-
-
84886739486
-
Prefrontal dopamine signaling and cognitive symptoms of parkinson's disease
-
Narayanan NS, Rodnitzky RL, Uc EY.Prefrontal dopamine signaling and cognitive symptoms of Parkinson's disease.Rev Neurosci 2013; 24(3): 267-78
-
(2013)
Rev Neurosci
, vol.24
, Issue.3
, pp. 267-278
-
-
Narayanan, N.S.1
Rodnitzky, R.L.2
Uc, E.Y.3
-
128
-
-
33749672231
-
A convergent model for cognitive dysfunctions in parkinson's disease: The critical dopamine-Acetylcholine synaptic balance
-
Calabresi P, Picconi B, Parnetti L, Di Filippo M.A convergent model for cognitive dysfunctions in Parkinson's disease: the critical dopamine-Acetylcholine synaptic balance.Lancet Neurol 2006; 5(11): 974-83
-
(2006)
Lancet Neurol
, vol.5
, Issue.11
, pp. 974-983
-
-
Calabresi, P.1
Picconi, B.2
Parnetti, L.3
Di Filippo, M.4
-
129
-
-
0035364748
-
Expanded cag repeats in exon 1 of the huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration
-
Petersén A, Larsen KE, Behr GG, et al.Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration.Hum Mol Genet 2001; 10(12): 1243-54
-
(2001)
Hum Mol Genet
, vol.10
, Issue.12
, pp. 1243-1254
-
-
Petersén, A.1
Larsen, K.E.2
Behr, G.G.3
-
130
-
-
83555173501
-
Potential endpoints for clinical trials in premanifest and early huntington's disease in the track-hd study: Analysis of 24 month observational data
-
Tabrizi SJ, Reilmann R, Roos RAC, et al.Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data.Lancet Neurol 2012; 11(1): 42-53
-
(2012)
Lancet Neurol
, vol.11
, Issue.1
, pp. 42-53
-
-
Tabrizi, S.J.1
Reilmann, R.2
Roos, R.A.C.3
-
131
-
-
84886401385
-
Clinical neurogenetics: Huntington disease
-
Bordelon YM.Clinical neurogenetics: Huntington disease.Neurol Clin 2013; 31(4): 1085-94
-
(2013)
Neurol Clin
, vol.31
, Issue.4
, pp. 1085-1094
-
-
Bordelon, Y.M.1
-
132
-
-
0024741260
-
Huntington disease: Tetrabenazine compared to haloperidol in the reduction of involuntary movements
-
Giménez-Roldán S, Mateo D.Huntington disease: tetrabenazine compared to haloperidol in the reduction of involuntary movements.Neurologia 1989.4(8): 282-7
-
(1989)
Neurologia
, vol.4
, Issue.8
, pp. 282-287
-
-
Giménez-Roldán, S.1
Mateo, D.2
-
133
-
-
0031953450
-
Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain d2 receptors, yet occupy high levels of these receptors
-
Seeman P, Tallerico T.Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors.Mol Psychiatry 1998; 3: 123-34
-
(1998)
Mol Psychiatry
, vol.3
, pp. 123-134
-
-
Seeman, P.1
Tallerico, T.2
-
134
-
-
0030790234
-
Clozapine versus placebo in huntington's disease: A double blind randomised comparative study
-
van Vugt JP, Siesling S, Vergeer van der Velde MEA, Roos RA.Clozapine versus placebo in Huntington's disease: a double blind randomised comparative study.J Neurol Neurosurg Psychiatry 63(1): 35-9
-
J Neurol Neurosurg Psychiatry
, vol.63
, Issue.1
, pp. 35-39
-
-
Van Vugt, J.P.1
Siesling, S.2
Vergeer Van Der Velde, M.E.A.3
Roos, R.A.4
-
135
-
-
0036178507
-
High-dose olanzapine in huntington's disease
-
Bonelli RM, Niederwieser G, Tribl GG, Költringer P.High-dose olanzapine in Huntington's disease.Int Clin Psychopharmacol 2002; 17(2): 91-3
-
(2002)
Int Clin Psychopharmacol
, vol.17
, Issue.2
, pp. 91-93
-
-
Bonelli, R.M.1
Niederwieser, G.2
Tribl, G.G.3
Költringer, P.4
-
136
-
-
77949834466
-
Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as d2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, acr16
-
Pettersson F, Pontén H, Waters N, et al.Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (Huntexil, pridopidine, ACR16).J Med Chem 2010; 53(6): 2510-20
-
(2010)
J Med Chem
, vol.53
, Issue.6
, pp. 2510-2520
-
-
Pettersson, F.1
Pontén, H.2
Waters, N.3
|