Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II

Human Molecular Genetics

Volumn 17, Issue 10, 2008, Pages 1446-1456

  Benchoua, Alexandra ^a   Trioulier, Yaël ^a   Diguet, Elsa ^a   Malgorn, Carole ^a   Gaillard, Marie Claude ^b   Dufour, Noelle ^a   Elalouf, Jean Marc ^b   Krajewski, Stan ^c   Hantraye, Philippe ^a   Déglon, Nicole ^a   Brouillet, Emmanuel ^a  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

^b SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROPROPIONIC ACID; DOPAMINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; HUNTINGTIN; LENTIVIRUS VECTOR; MITOCHONDRIAL COMPLEX II; OXIDOREDUCTASE;

AEROBIC METABOLISM; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DEATH; CELL LOSS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORPUS STRIATUM; DEGENERATIVE DISEASE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; EMBRYO; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME REGULATION; GENE OVEREXPRESSION; HUNTINGTON CHOREA; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

EID: 43049085555     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn033     Document Type: Article

References (46)