-
1
-
-
84868336049
-
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
-
Jostins L, Ripke S, Weersma RK, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012;491:119-124.
-
(2012)
Nature
, vol.491
, pp. 119-124
-
-
Jostins, L.1
Ripke, S.2
Weersma, R.K.3
-
3
-
-
35449000411
-
Has toll-like receptor 4 been prematurely dismissed as an inflammatory bowel disease gene? Association study combined with meta-analysis shows strong evidence for association
-
Browning BL, Huebner C, Petermann I, et al. Has toll-like receptor 4 been prematurely dismissed as an inflammatory bowel disease gene? Association study combined with meta-analysis shows strong evidence for association. Am J Gastroenterol. 2007;102:2504-2512.
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 2504-2512
-
-
Browning, B.L.1
Huebner, C.2
Petermann, I.3
-
4
-
-
0033910870
-
Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
-
Rioux JD, Silverberg MS, Daly MJ, et al. Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. Am J Hum Genet. 2000;66:1863-1870.
-
(2000)
Am J Hum Genet.
, vol.66
, pp. 1863-1870
-
-
Rioux, J.D.1
Silverberg, M.S.2
Daly, M.J.3
-
5
-
-
84896494996
-
Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium
-
Mokry M, Middendorp S, Wiegerinck CL, et al. Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium. Gastroenterology. 2014;146: 1040-1047.
-
(2014)
Gastroenterology
, vol.146
, pp. 1040-1047
-
-
Mokry, M.1
Middendorp, S.2
Wiegerinck, C.L.3
-
6
-
-
84888371687
-
Complement factor B is the downstream effector of TLRs and plays an important role in a mouse model of severe sepsis
-
Zou L, Feng Y, Li Y, et al. Complement factor B is the downstream effector of TLRs and plays an important role in a mouse model of severe sepsis. J Immunol. 2013;191:5625-5635.
-
(2013)
J Immunol.
, vol.191
, pp. 5625-5635
-
-
Zou, L.1
Feng, Y.2
Li, Y.3
-
7
-
-
77950187449
-
Crosstalk pathways between Toll-like receptors and the complement system
-
Hajishengallis G, Lambris JD. Crosstalk pathways between Toll-like receptors and the complement system. Trends Immunol. 2010;31:154-163.
-
(2010)
Trends Immunol.
, vol.31
, pp. 154-163
-
-
Hajishengallis, G.1
Lambris, J.D.2
-
8
-
-
84879885078
-
The role of complement in CD4(+) T cell homeostasis and effector functions
-
Kolev M, Le Friec G, Kemper C. The role of complement in CD4(+) T cell homeostasis and effector functions. Semin Immunol. 2013;25: 12-19.
-
(2013)
Semin Immunol.
, vol.25
, pp. 12-19
-
-
Kolev, M.1
Le Friec, G.2
Kemper, C.3
-
9
-
-
84880682970
-
Humoral pattern recognition and the complement system
-
Degn SE, Thiel S. Humoral pattern recognition and the complement system. Scand J Immunol. 2013;78:181-193.
-
(2013)
Scand J Immunol.
, vol.78
, pp. 181-193
-
-
Degn, S.E.1
Thiel, S.2
-
10
-
-
84875990477
-
Complement in immune and inflammatory disorders: Therapeutic interventions
-
Ricklin D, Lambris JD. Complement in immune and inflammatory disorders: therapeutic interventions. J Immunol. 2013;190:3839-3847.
-
(2013)
J Immunol.
, vol.190
, pp. 3839-3847
-
-
Ricklin, D.1
Lambris, J.D.2
-
11
-
-
79952835560
-
New insights of an old defense system: Structure, function, and clinical relevance of the complement system
-
Ehrnthaller C, Ignatius A, Gebhard F, et al. New insights of an old defense system: structure, function, and clinical relevance of the complement system. Molr Med. 2011;17:317-329.
-
(2011)
Molr Med.
, vol.17
, pp. 317-329
-
-
Ehrnthaller, C.1
Ignatius, A.2
Gebhard, F.3
-
12
-
-
33744987414
-
Generation of C5a in the absence of C3: A new complement activation pathway
-
Huber-Lang M, Sarma JV, Zetoune FS, et al. Generation of C5a in the absence of C3: a new complement activation pathway. Nat Med. 2006;12: 682-687.
-
(2006)
Nat Med.
, vol.12
, pp. 682-687
-
-
Huber-Lang, M.1
Sarma, J.V.2
Zetoune, F.S.3
-
13
-
-
79955940012
-
Haemostatic system in inflammatory bowel diseases: New players in gut inflammation
-
Scaldaferri F, Lancellotti S, Pizzoferrato M, et al. Haemostatic system in inflammatory bowel diseases: new players in gut inflammation. World J Gastroenterol. 2011;17:594-608.
-
(2011)
World J Gastroenterol
, vol.17
, pp. 594-608
-
-
Scaldaferri, F.1
Lancellotti, S.2
Pizzoferrato, M.3
-
14
-
-
84891788136
-
Inflammatory bowel disease: Epidemiology, pathology and risk factors for hypercoagulability
-
Owczarek D, Cibor D, Glowacki MK, et al. Inflammatory bowel disease: epidemiology, pathology and risk factors for hypercoagulability. World J Gastroenterol. 2014;20:53-63.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 53-63
-
-
Owczarek, D.1
Cibor, D.2
Glowacki, M.K.3
-
15
-
-
79961053729
-
C4b-binding protein: A forgotten factor in thrombosis and hemostasis
-
Dahlbäck B. C4b-binding protein: a forgotten factor in thrombosis and hemostasis. Semin Thromb Hemost. 2011;37:355-361.
-
(2011)
Semin Thromb Hemost.
, vol.37
, pp. 355-361
-
-
Dahlbäck, B.1
-
16
-
-
67649220651
-
Pentraxins: Multifunctional proteins at the interface of innate immunity and inflammation
-
Deban L, Bottazzi B, Garlanda C, et al. Pentraxins: multifunctional proteins at the interface of innate immunity and inflammation. Biofactors. 2009;35:138-145.
-
(2009)
Biofactors
, vol.35
, pp. 138-145
-
-
Deban, L.1
Bottazzi, B.2
Garlanda, C.3
-
17
-
-
84892979466
-
Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: A retrospective analysis of the ACCENT I trial
-
Cornillie F, Hanauer SB, Diamond RH, et al. Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: a retrospective analysis of the ACCENT I trial. Gut. 2014. doi:10.1136/gutjnl- 2012-304094.
-
(2014)
Gut.
-
-
Cornillie, F.1
Hanauer, S.B.2
Diamond, R.H.3
-
18
-
-
79954994711
-
Levels of C-reactive protein are associated with response to infliximab therapy in patients with Crohn's disease
-
Jürgens M, Mahachie John JM, Cleynen I, et al. Levels of C-reactive protein are associated with response to infliximab therapy in patients with Crohn's disease. Clin Gastroenterol Hepatol. 2011;9:421-427.
-
(2011)
Clin Gastroenterol Hepatol.
, vol.9
, pp. 421-427
-
-
Jürgens, M.1
Mahachie John, J.M.2
Cleynen, I.3
-
19
-
-
0242330331
-
Complement activation in plasma before and after infliximab treatment in Crohn disease
-
Zimmermann-Nielsen E, Agnholt J, Thorlacius-Ussing O, et al. Complement activation in plasma before and after infliximab treatment in Crohn disease. Scand J Gastroenterol. 2003;38:1050-1054.
-
(2003)
Scand J Gastroenterol
, vol.38
, pp. 1050-1054
-
-
Zimmermann-Nielsen, E.1
Agnholt, J.2
Thorlacius-Ussing, O.3
-
20
-
-
84865389455
-
Regulation of humoral immunity by complement
-
Carroll MC, Isenman DE. Regulation of humoral immunity by complement. Immunity. 2012;37:199-207.
-
(2012)
Immunity
, vol.37
, pp. 199-207
-
-
Carroll, M.C.1
Isenman, D.E.2
-
21
-
-
40249116606
-
Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells
-
Strainic MG, Liu J, Huang D, et al. Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. Immunity. 2008;28:425-435.
-
(2008)
Immunity
, vol.28
, pp. 425-435
-
-
Strainic, M.G.1
Liu, J.2
Huang, D.3
-
22
-
-
0347895101
-
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
-
Kemper C, Chan AC, Green JM, et al. Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature. 2003;421:388-392.
-
(2003)
Nature
, vol.421
, pp. 388-392
-
-
Kemper, C.1
Chan, A.C.2
Green, J.M.3
-
23
-
-
84855296204
-
Novel roles of complement in T effector cell regulation
-
Heeger PS, Kemper C. Novel roles of complement in T effector cell regulation. Immunobiology. 2012;217:216-224.
-
(2012)
Immunobiology
, vol.217
, pp. 216-224
-
-
Heeger, P.S.1
Kemper, C.2
-
25
-
-
76749086068
-
Molecular mechanisms of late apoptotic/necrotic cell clearance
-
Poon IKH, Hulett MD, Parish CR. Molecular mechanisms of late apoptotic/necrotic cell clearance. Cell Death Differ. 2010;17:381-397.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 381-397
-
-
Poon, I.K.H.1
Hulett, M.D.2
Parish, C.R.3
-
26
-
-
81155154243
-
Eculizumab: A review of its use in paroxysmal nocturnal haemoglobinuria
-
McKeage K. Eculizumab: a review of its use in paroxysmal nocturnal haemoglobinuria. Drugs. 2011;71:2327-2345.
-
(2011)
Drugs
, vol.71
, pp. 2327-2345
-
-
McKeage, K.1
-
27
-
-
84888127097
-
A systematic review of eculizumab for atypical haemolytic uraemic syndrome (aHUS)
-
Rathbone J, Kaltenthaler E, Richards A, et al. A systematic review of eculizumab for atypical haemolytic uraemic syndrome (aHUS). BMJ Open. 2013;3:e003573
-
(2013)
BMJ Open
, vol.3
, pp. e003573
-
-
Rathbone, J.1
Kaltenthaler, E.2
Richards, A.3
-
28
-
-
0030013492
-
Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library
-
Sahu A, Kay BK, Lambris JD. Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library. J Immunol. 1996;157:884-891.
-
(1996)
J Immunol.
, vol.157
, pp. 884-891
-
-
Sahu, A.1
Kay, B.K.2
Lambris, J.D.3
-
29
-
-
84875244143
-
New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties
-
Qu H, Ricklin D, Bai H, et al. New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties. Immunobiology. 2013;218:496-505.
-
(2013)
Immunobiology
, vol.218
, pp. 496-505
-
-
Qu, H.1
Ricklin, D.2
Bai, H.3
-
30
-
-
84865693626
-
Safety and efficacy of prophylactic nanofiltered C1-inhibitor in hereditary angioedema
-
Zuraw BL, Kalfus I. Safety and efficacy of prophylactic nanofiltered C1-inhibitor in hereditary angioedema. Am J Med. 2012;125:938.e1-e7.
-
(2012)
Am J Med.
, vol.125
, pp. e1-e7
-
-
Zuraw, B.L.1
Kalfus, I.2
-
31
-
-
42649089750
-
Anti-inflammatory actions of intravenous immunoglobulin
-
Nimmerjahn F, Ravetch JV. Anti-inflammatory actions of intravenous immunoglobulin. Annu Rev Immunol. 2008;26:513-533.
-
(2008)
Annu Rev Immunol.
, vol.26
, pp. 513-533
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
32
-
-
84870242832
-
Intravenous immunoglobulin for the treatment of Crohn's disease
-
Rogosnitzky M, Danks R, Holt D. Intravenous immunoglobulin for the treatment of Crohn's disease. Autoimmun Rev. 2012;12:275-280.
-
(2012)
Autoimmun Rev.
, vol.12
, pp. 275-280
-
-
Rogosnitzky, M.1
Danks, R.2
Holt, D.3
-
33
-
-
29944443463
-
Anti-inflammatory effect of intravenous immunoglobulin mediated through modulation of complement activation
-
Lutz HU, Späth PJ. Anti-inflammatory effect of intravenous immunoglobulin mediated through modulation of complement activation. Clin Rev Allergy Immunol. 2005;29:207.
-
(2005)
Clin Rev Allergy Immunol.
, vol.29
, pp. 207
-
-
Lutz, H.U.1
Späth, P.J.2
-
34
-
-
0029950559
-
Local secretion of complement C3 in the exocrine pancreas: Ductal epithelial cells as a possible biosynthetic site
-
Andoh A, Fujiyama Y, Sumiyoshi K, et al. Local secretion of complement C3 in the exocrine pancreas: ductal epithelial cells as a possible biosynthetic site. Gastroenterology. 1996;110:1919-1925.
-
(1996)
Gastroenterology
, vol.110
, pp. 1919-1925
-
-
Andoh, A.1
Fujiyama, Y.2
Sumiyoshi, K.3
-
35
-
-
0034077161
-
Cellular localization of complement C3 and C4 transcripts in intestinal specimens from patients with Crohn's disease
-
Laufer J, Oren R, Goldberg I, et al. Cellular localization of complement C3 and C4 transcripts in intestinal specimens from patients with Crohn's disease. Clin Exp Immunol. 2000;120:30-37.
-
(2000)
Clin Exp Immunol.
, vol.120
, pp. 30-37
-
-
Laufer, J.1
Oren, R.2
Goldberg, I.3
-
36
-
-
77952222918
-
The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease
-
Sugihara T, Kobori A, Imaeda H, et al. The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease. Clin Exp Immunol. 2010;160:386-393.
-
(2010)
Clin Exp Immunol.
, vol.160
, pp. 386-393
-
-
Sugihara, T.1
Kobori, A.2
Imaeda, H.3
-
37
-
-
0030807208
-
Local and systemic complement activity in small intestinal bacterial overgrowth
-
Riordan SM, McIver CJ, Wakefield D, et al. Local and systemic complement activity in small intestinal bacterial overgrowth. Dig Dis Sci. 1997; 42:1128-1136.
-
(1997)
Dig Dis Sci.
, vol.42
, pp. 1128-1136
-
-
Riordan, S.M.1
McIver, C.J.2
Wakefield, D.3
-
38
-
-
0025239287
-
Enhanced local production of complement components in the small intestines of patients with Crohn's disease
-
Ahrenstedt O, Knutson L, Nilsson B, et al. Enhanced local production of complement components in the small intestines of patients with Crohn's disease. N Engl J Med. 1990;322:1345-1349.
-
(1990)
N Engl J Med.
, vol.322
, pp. 1345-1349
-
-
Ahrenstedt, O.1
Knutson, L.2
Nilsson, B.3
-
39
-
-
0029852446
-
The expression of complement protein 4 and IgG3 in luminal secretions
-
Riordan SM, McIver CJ, Thomas MC, et al. The expression of complement protein 4 and IgG3 in luminal secretions. Scand J Gastroenterol. 1996;31:1098-1102.
-
(1996)
Scand J Gastroenterol
, vol.31
, pp. 1098-1102
-
-
Riordan, S.M.1
McIver, C.J.2
Thomas, M.C.3
-
40
-
-
0021923695
-
Familial occurrence of complement dysfunction in Crohn's disease: Correlation with intestinal symptoms and hypercatabolism of complement
-
Elmgreen J, Both H, Binder V. Familial occurrence of complement dysfunction in Crohn's disease: correlation with intestinal symptoms and hypercatabolism of complement. Gut. 1985;26:151-157.
-
(1985)
Gut.
, vol.26
, pp. 151-157
-
-
Elmgreen, J.1
Both, H.2
Binder, V.3
-
41
-
-
0027526976
-
Differential cytokine regulation of complement C3, C4, and factor B synthesis in human intestinal epithelial cell line, Caco-2
-
Andoh A, Fujiyama Y, Bamba T, et al. Differential cytokine regulation of complement C3, C4, and factor B synthesis in human intestinal epithelial cell line, Caco-2. J Immunol. 1993;151:4239-4247.
-
(1993)
J Immunol.
, vol.151
, pp. 4239-4247
-
-
Andoh, A.1
Fujiyama, Y.2
Bamba, T.3
-
42
-
-
0030024046
-
Differential expression of complement proteins and regulatory decay accelerating factor in relation to differentiation of cultured human colon adenocarcinoma cell lines
-
Bernet-Camard MF, Coconnier MH, Hudault S, et al. Differential expression of complement proteins and regulatory decay accelerating factor in relation to differentiation of cultured human colon adenocarcinoma cell lines. Gut. 1996;38:248-253.
-
(1996)
Gut.
, vol.38
, pp. 248-253
-
-
Bernet-Camard, M.F.1
Coconnier, M.H.2
Hudault, S.3
-
43
-
-
84874276193
-
Local release of properdin in the cellular microenvironment: Role in pattern recognition and amplification of the alternative pathway of complement
-
Cortes C, Ohtola JA, Saggu G, et al. Local release of properdin in the cellular microenvironment: role in pattern recognition and amplification of the alternative pathway of complement. Front Immunol. 2013;3:412.
-
(2013)
Front Immunol.
, vol.3
, pp. 412
-
-
Cortes, C.1
Ohtola, J.A.2
Saggu, G.3
-
44
-
-
0031135489
-
Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils
-
Wirthmueller U, Dewald B, Thelen M, et al. Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils. J Immunol. 1997;158:4444-4451.
-
(1997)
J Immunol.
, vol.158
, pp. 4444-4451
-
-
Wirthmueller, U.1
Dewald, B.2
Thelen, M.3
-
45
-
-
0031925365
-
Expression of cell membrane complement regulatory glycoproteins along the normal and diseased human gastrointestinal tract
-
Berstad AE, Brandtzaeg P. Expression of cell membrane complement regulatory glycoproteins along the normal and diseased human gastrointestinal tract. Gut. 1998;42:522-529.
-
(1998)
Gut.
, vol.42
, pp. 522-529
-
-
Berstad, A.E.1
Brandtzaeg, P.2
-
46
-
-
0023222304
-
Identification of the complement decay-accelerating factor (DAF) on epithelium and glandular cells and in body fluids
-
Medof ME, Walter EI, Rutgers JL, et al. Identification of the complement decay-accelerating factor (DAF) on epithelium and glandular cells and in body fluids. J Exp Med. 1987;165:848-864.
-
(1987)
J Exp Med.
, vol.165
, pp. 848-864
-
-
Medof, M.E.1
Walter, E.I.2
Rutgers, J.L.3
-
47
-
-
0035478342
-
Intestinal trefoil factor induces decay-accelerating factor expression and enhances the protective activities against complement activation in intestinal epithelial cells
-
Andoh A, Kinoshita K, Rosenberg I, et al. Intestinal trefoil factor induces decay-accelerating factor expression and enhances the protective activities against complement activation in intestinal epithelial cells. J Immunol. 2001;167:3887-3893.
-
(2001)
J Immunol.
, vol.167
, pp. 3887-3893
-
-
Andoh, A.1
Kinoshita, K.2
Rosenberg, I.3
-
48
-
-
84862610368
-
Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway
-
Cao Q, McIsaac SM, Stadnyk AW. Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway. Am J Physiol Cell Physiol. 2012;302:C1731-C1740.
-
(2012)
Am J Physiol Cell Physiol.
, vol.302
, pp. C1731-C1740
-
-
Cao, Q.1
McIsaac, S.M.2
Stadnyk, A.W.3
-
49
-
-
0026649732
-
Surface epithelium related activation of complement differs in Crohn's disease and ulcerative colitis
-
Halstensen TS, Mollnes TE, Garred P, et al. Surface epithelium related activation of complement differs in Crohn's disease and ulcerative colitis. Gut. 1992;33:902-908.
-
(1992)
Gut.
, vol.33
, pp. 902-908
-
-
Halstensen, T.S.1
Mollnes, T.E.2
Garred, P.3
-
50
-
-
0025320911
-
Epithelial deposition of immunoglobulin G1 and activated complement (C3b and terminal complement complex) in ulcerative colitis
-
Halstensen TS, Mollnes TE, Garred P, et al. Epithelial deposition of immunoglobulin G1 and activated complement (C3b and terminal complement complex) in ulcerative colitis. Gastroenterology. 1990;98:1264-1271.
-
(1990)
Gastroenterology
, vol.98
, pp. 1264-1271
-
-
Halstensen, T.S.1
Mollnes, T.E.2
Garred, P.3
-
51
-
-
9244231203
-
Distribution of activated complement, C3b, and its degraded fragments, iC3b/C3dg, in the colonic mucosa of ulcerative colitis (UC)
-
Ueki T, Mizuno M, Uesu T, et al. Distribution of activated complement, C3b, and its degraded fragments, iC3b/C3dg, in the colonic mucosa of ulcerative colitis (UC). Clin Exp Immunol. 1996;104:286-292.
-
(1996)
Clin Exp Immunol.
, vol.104
, pp. 286-292
-
-
Ueki, T.1
Mizuno, M.2
Uesu, T.3
-
52
-
-
1542619243
-
Decay-accelerating factor deficiency increases susceptibility to dextran sulfate sodium-induced colitis: Role for complement in inflammatory bowel disease
-
Lin F, Spencer D, Hatala DA, et al. Decay-accelerating factor deficiency increases susceptibility to dextran sulfate sodium-induced colitis: role for complement in inflammatory bowel disease. J Immunol. 2004;172:3836-3841.
-
(2004)
J Immunol.
, vol.172
, pp. 3836-3841
-
-
Lin, F.1
Spencer, D.2
Hatala, D.A.3
-
54
-
-
0016743855
-
Humoral immune system activity in inflammatory bowel disease
-
Teisberg P, Gjone E. Humoral immune system activity in inflammatory bowel disease. Scand J Gastroenterol. 1975;10:545-549.
-
(1975)
Scand J Gastroenterol
, vol.10
, pp. 545-549
-
-
Teisberg, P.1
Gjone, E.2
-
55
-
-
0021020641
-
Hypercatabolism of complement in Crohn's disease-assessment of circulating C3c
-
Elmgreen J, Berkowicz A, Sorensen H. Hypercatabolism of complement in Crohn's disease-assessment of circulating C3c. Acta Med Scand. 1983;214:403-407.
-
(1983)
Acta Med Scand.
, vol.214
, pp. 403-407
-
-
Elmgreen, J.1
Berkowicz, A.2
Sorensen, H.3
-
56
-
-
0017662309
-
Humoral immune system in inflammatory bowel disease: I. Complement levels
-
Hodgson HJF, Potter BJ, Jewell DP. Humoral immune system in inflammatory bowel disease: I. Complement levels. Gut. 1977;18:749-753.
-
(1977)
Gut.
, vol.18
, pp. 749-753
-
-
Hodgson, H.J.F.1
Potter, B.J.2
Jewell, D.P.3
-
57
-
-
0017239640
-
The alternate complement pathway in inflammatory bowel disease. Quantitation of the C3 proactivator (factor B) protein
-
Feinstein PA, Kaplan SR, Thayer WR. The alternate complement pathway in inflammatory bowel disease. Quantitation of the C3 proactivator (factor B) protein. Gastroenterology. 1976;70:181-185.
-
(1976)
Gastroenterology
, vol.70
, pp. 181-185
-
-
Feinstein, P.A.1
Kaplan, S.R.2
Thayer, W.R.3
-
58
-
-
0016653092
-
Serum C3 and C4 complement components in ulcerative colitis and Crohn's disease
-
Ward M, Eastwood MA. Serum C3 and C4 complement components in ulcerative colitis and Crohn's disease. Digestion. 1975;13:100-103.
-
(1975)
Digestion
, vol.13
, pp. 100-103
-
-
Ward, M.1
Eastwood, M.A.2
-
59
-
-
0020033381
-
Circulating immune complexes in Crohn's disease. Their characterization and interrelationship with components of the complement system
-
Richens ER, Thorpe CM, Bland P, et al. Circulating immune complexes in Crohn's disease. Their characterization and interrelationship with components of the complement system. Dig Dis Sci. 1982;27:129-138.
-
(1982)
Dig Dis Sci.
, vol.27
, pp. 129-138
-
-
Richens, E.R.1
Thorpe, C.M.2
Bland, P.3
-
60
-
-
0037865427
-
High normal serum levels of C3 and C1 inhibitor, two acute phase proteins belonging to the complement system, occur more frequently in patients with Crohn's disease than ulcerative colitis
-
Bene L, Füst G, Fekete B, et al. High normal serum levels of C3 and C1 inhibitor, two acute phase proteins belonging to the complement system, occur more frequently in patients with Crohn's disease than ulcerative colitis. Dig Dis Sci. 2003;48:1186-1192.
-
(2003)
Dig Dis Sci.
, vol.48
, pp. 1186-1192
-
-
Bene, L.1
Füst, G.2
Fekete, B.3
-
61
-
-
0018375589
-
Complement alterations in inflammatory bowel disease
-
Lake AM, Stitzel AE, Urmson JR, et al. Complement alterations in inflammatory bowel disease. Gastroenterology. 1979;76:1374-1379.
-
(1979)
Gastroenterology
, vol.76
, pp. 1374-1379
-
-
Lake, A.M.1
Stitzel, A.E.2
Urmson, J.R.3
-
62
-
-
0020582765
-
Defective release of C5a related chemo-attractant activity from complement in Crohn's disease
-
Elmgreen J, Berkowicz A, Sorensen H. Defective release of C5a related chemo-attractant activity from complement in Crohn's disease. Gut. 1983; 24:525-531.
-
(1983)
Gut.
, vol.24
, pp. 525-531
-
-
Elmgreen, J.1
Berkowicz, A.2
Sorensen, H.3
-
63
-
-
26444572774
-
Complement activation capacity in plasma before and during high-dose prednisolone treatment and tapering in exacerbations of Crohn's disease and ulcerative colitis
-
Zimmermann-Nielsen E, Grønbaek H, Dahlerup JF, et al. Complement activation capacity in plasma before and during high-dose prednisolone treatment and tapering in exacerbations of Crohn's disease and ulcerative colitis. BMC Gastroenterol. 2005;5:31.
-
(2005)
BMC Gastroenterol
, vol.5
, pp. 31
-
-
Zimmermann-Nielsen, E.1
Grønbaek, H.2
Dahlerup, J.F.3
-
64
-
-
84899932528
-
The lectin pathway of the complement system is downregulated in Crohn's disease patients who respond to anti-TNF-α therapy
-
Sandahl TD, Kelsen J, Dige A, et al. The lectin pathway of the complement system is downregulated in Crohn's disease patients who respond to anti-TNF-α therapy. J Crohns Colitis. 2014;8:521-528.
-
(2014)
J Crohns Colitis.
, vol.8
, pp. 521-528
-
-
Sandahl, T.D.1
Kelsen, J.2
Dige, A.3
-
65
-
-
0034794226
-
Colitis associated with deficiency of the sixth component of complement and congenital chronic neutropenia
-
Matsubaysahi T, Kaneko S, Shimizu M, et al. Colitis associated with deficiency of the sixth component of complement and congenital chronic neutropenia. Acta Paediatr. 2001;90:1211-1212.
-
(2001)
Acta Paediatr.
, vol.90
, pp. 1211-1212
-
-
Matsubaysahi, T.1
Kaneko, S.2
Shimizu, M.3
-
66
-
-
78249259690
-
Inflammatory bowel disease in patients with adaptive and complement immunodeficiency disorders
-
Marks DJB, Seymour CR, Sewell GW, et al. Inflammatory bowel disease in patients with adaptive and complement immunodeficiency disorders. Inflamm Bowel Dis. 2010;16:1984-1992.
-
(2010)
Inflamm Bowel Dis.
, vol.16
, pp. 1984-1992
-
-
Marks, D.J.B.1
Seymour, C.R.2
Sewell, G.W.3
-
67
-
-
84858078015
-
Mannan-binding lectin deficiency-Good news, bad news, doesn't matter?
-
Heitzeneder S, Seidel M, Förster-Waldl E, et al. Mannan-binding lectin deficiency-Good news, bad news, doesn't matter? Clin Immunol. 2012; 143:22-38.
-
(2012)
Clin Immunol.
, vol.143
, pp. 22-38
-
-
Heitzeneder, S.1
Seidel, M.2
Förster-Waldl, E.3
-
68
-
-
84875619547
-
Ficolins in complement activation
-
Matsushita M. Ficolins in complement activation. Mol Immunol. 2013;55: 22-26.
-
(2013)
Mol Immunol.
, vol.55
, pp. 22-26
-
-
Matsushita, M.1
-
69
-
-
84872165018
-
Increased titers of anti-Saccharomyces cerevisiae antibodies in Crohn's disease patients with reduced H-ficolin levels but normal MASP-2 activity
-
Schaffer T, Flogerzi B, Schoepfer AM, et al. Increased titers of anti-Saccharomyces cerevisiae antibodies in Crohn's disease patients with reduced H-ficolin levels but normal MASP-2 activity. J Crohns Colitis. 2013;7:e1-e10.
-
(2013)
J Crohns Colitis.
, vol.7
, pp. e1-e10
-
-
Schaffer, T.1
Flogerzi, B.2
Schoepfer, A.M.3
-
70
-
-
33750984530
-
Mannose-binding lectin and maladies of the bowel and liver
-
Worthley DL, Bardy PG, Gordon DL, et al. Mannose-binding lectin and maladies of the bowel and liver. World J Gastroenterol. 2006;12: 6420-6428.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 6420-6428
-
-
Worthley, D.L.1
Bardy, P.G.2
Gordon, D.L.3
-
71
-
-
78049515838
-
Mannan-binding lectin deficiency results in unusual antibody production and excessive experimental colitis in response to mannose-expressing mild gut pathogens
-
Müller S, Schaffer T, Flogerzi B, et al. Mannan-binding lectin deficiency results in unusual antibody production and excessive experimental colitis in response to mannose-expressing mild gut pathogens. Gut. 2010;59: 1493-1500.
-
(2010)
Gut.
, vol.59
, pp. 1493-1500
-
-
Müller, S.1
Schaffer, T.2
Flogerzi, B.3
-
72
-
-
77950542010
-
Mannose-binding lectin level and deficiency is not associated with inflammatory bowel diseases, disease phenotype, serology profile, and NOD2/CARD15 genotype in a large Hungarian cohort
-
Papp M, Lakatos PL, Harsfalvi J, et al. Mannose-binding lectin level and deficiency is not associated with inflammatory bowel diseases, disease phenotype, serology profile, and NOD2/CARD15 genotype in a large Hungarian cohort. Hum Immunol. 2010;71:407-413.
-
(2010)
Hum Immunol.
, vol.71
, pp. 407-413
-
-
Papp, M.1
Lakatos, P.L.2
Harsfalvi, J.3
-
73
-
-
0035491059
-
Mannan-binding lectin (MBL) gene polymorphisms in ulcerative colitis and Crohn's disease
-
Rector A, Lemey P, Laffut W, et al. Mannan-binding lectin (MBL) gene polymorphisms in ulcerative colitis and Crohn's disease. Genes Immun. 2001;2:323-328.
-
(2001)
Genes Immun.
, vol.2
, pp. 323-328
-
-
Rector, A.1
Lemey, P.2
Laffut, W.3
-
74
-
-
83455213646
-
Association of genetic variants of mannan-binding (MBL) lectin-2 gene, MBL levels and function in ulcerative colitis and Crohn's disease
-
Sivaram G, Tiwari SK, Bardia A, et al. Association of genetic variants of mannan-binding (MBL) lectin-2 gene, MBL levels and function in ulcerative colitis and Crohn's disease. Innate Immun. 2010;17:526-531.
-
(2010)
Innate Immun.
, vol.17
, pp. 526-531
-
-
Sivaram, G.1
Tiwari, S.K.2
Bardia, A.3
-
75
-
-
39149145810
-
The role of mannan-binding lectin (MBL) gene polymorphism in ulcerative colitis
-
Wang FY, Arisawa T, Tahara T, et al. The role of mannan-binding lectin (MBL) gene polymorphism in ulcerative colitis. J Clin Biochem Nutr. 2008;42:54-58.
-
(2008)
J Clin Biochem Nutr.
, vol.42
, pp. 54-58
-
-
Wang, F.Y.1
Arisawa, T.2
Tahara, T.3
-
76
-
-
80052904799
-
Mannan-binding lectin deficiency in pediatric patients with inflammatory bowel disease
-
Bak-Romaniszyn L, Szala A, Sokolowska A, et al. Mannan-binding lectin deficiency in pediatric patients with inflammatory bowel disease. Scand J Gastroenterol. 2011;46:1275-1278.
-
(2011)
Scand J Gastroenterol
, vol.46
, pp. 1275-1278
-
-
Bak-Romaniszyn, L.1
Szala, A.2
Sokolowska, A.3
-
77
-
-
84872490526
-
Low mannose-binding lectin (MBL) is associated with paediatric inflammatory bowel diseases and ileal involvement in patients with Crohn disease
-
Kovacs M, Papp M, Lakatos PL, et al. Low mannose-binding lectin (MBL) is associated with paediatric inflammatory bowel diseases and ileal involvement in patients with Crohn disease. J Crohns Colitis. 2013;7: 134-141.
-
(2013)
J Crohns Colitis.
, vol.7
, pp. 134-141
-
-
Kovacs, M.1
Papp, M.2
Lakatos, P.L.3
-
78
-
-
0027425407
-
Multifunctional effects of anticomplementary agent K-76 on carrageenan-induced colitis in rabbits
-
Kitano A, Matsumoto T, Nakamura S, et al. Multifunctional effects of anticomplementary agent K-76 on carrageenan-induced colitis in rabbits. Clin Exp Immunol. 1993;94:348-353.
-
(1993)
Clin Exp Immunol.
, vol.94
, pp. 348-353
-
-
Kitano, A.1
Matsumoto, T.2
Nakamura, S.3
-
80
-
-
0030664895
-
Complement activation of electrogenic ion transport in isolated rat colon
-
McCole DF, Otti B, Newsholme P, et al. Complement activation of electrogenic ion transport in isolated rat colon. Biochem Pharmacol. 1997;54: 1133-1137.
-
(1997)
Biochem Pharmacol.
, vol.54
, pp. 1133-1137
-
-
McCole, D.F.1
Otti, B.2
Newsholme, P.3
-
81
-
-
0242494255
-
A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease
-
Woodruff TM, Arumugam TV, Sheils IA, et al. A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease. J Immunol. 2003;171:5514-5520.
-
(2003)
J Immunol.
, vol.171
, pp. 5514-5520
-
-
Woodruff, T.M.1
Arumugam, T.V.2
Sheils, I.A.3
-
82
-
-
84871575617
-
The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10
-
Jain U, Woodruff TM, Stadnyk AW. The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10. Br J Pharmacol. 2013;168:488-501.
-
(2013)
Br J Pharmacol.
, vol.168
, pp. 488-501
-
-
Jain, U.1
Woodruff, T.M.2
Stadnyk, A.W.3
-
83
-
-
79952081601
-
Blockade of complement activation product C5a activity using specific antibody attenuates intestinal damage in trinitrobenezene sulfonic acid induced model of colitis
-
Chen G, Yang Y, Gao X, et al. Blockade of complement activation product C5a activity using specific antibody attenuates intestinal damage in trinitrobenezene sulfonic acid induced model of colitis. Lab Invest. 2010;91:472-483.
-
(2010)
Lab Invest.
, vol.91
, pp. 472-483
-
-
Chen, G.1
Yang, Y.2
Gao, X.3
-
84
-
-
72549105677
-
Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease
-
Johswich K, Martin M, Bleich A, et al. Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease. Inflamm Bowel Dis. 2009;15:1812-1823.
-
(2009)
Inflamm Bowel Dis.
, vol.15
, pp. 1812-1823
-
-
Johswich, K.1
Martin, M.2
Bleich, A.3
-
85
-
-
0038730729
-
Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice
-
Naito Y, Takagi T, Handa O, et al. Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice. J Gastroenterol Hepatol. 2003;18:560-569.
-
(2003)
J Gastroenterol Hepatol.
, vol.18
, pp. 560-569
-
-
Naito, Y.1
Takagi, T.2
Handa, O.3
-
86
-
-
0029795542
-
The C5a chemoattractant receptor mediates mucosal defence to infection
-
Höpken UE, Lu B, Gerard NP, et al. The C5a chemoattractant receptor mediates mucosal defence to infection. Nature. 1996;383:86-89.
-
(1996)
Nature
, vol.383
, pp. 86-89
-
-
Höpken, U.E.1
Lu, B.2
Gerard, N.P.3
-
87
-
-
33644672010
-
Development of dextran sufate sodium-induced colitis is aggravated in mice genetically deficient for complement C5
-
Deguchi Y, Andoh A, Inatomi O, et al. Development of dextran sufate sodium-induced colitis is aggravated in mice genetically deficient for complement C5. Int J Mol Med. 2005;16:605-608.
-
(2005)
Int J Mol Med.
, vol.16
, pp. 605-608
-
-
Deguchi, Y.1
Andoh, A.2
Inatomi, O.3
-
88
-
-
84872353454
-
Neutralization of complement component C5 ameliorates the development of dextran sulfate sodium (DSS)-colitis in mice
-
Aomatsu T, Imaeda H, Takahashi K, et al. Neutralization of complement component C5 ameliorates the development of dextran sulfate sodium (DSS)-colitis in mice. J Clin Biochem Nutr. 2013;52:72-75.
-
(2013)
J Clin Biochem Nutr.
, vol.52
, pp. 72-75
-
-
Aomatsu, T.1
Imaeda, H.2
Takahashi, K.3
-
90
-
-
38449103815
-
The role of dendritic cells in the development of acute dextran sulfate sodium colitis
-
Berndt BE, Zhang M, Chen GH, et al. The role of dendritic cells in the development of acute dextran sulfate sodium colitis. J Immunol. 2007; 179:6255-6262.
-
(2007)
J Immunol.
, vol.179
, pp. 6255-6262
-
-
Berndt, B.E.1
Zhang, M.2
Chen, G.H.3
-
91
-
-
33751549013
-
Suppression of experimental colitis by intestinal mononuclear phagocytes
-
Qualls JE, Kaplan AM, Van Rooijen N, et al. Suppression of experimental colitis by intestinal mononuclear phagocytes. J Leukoc Biol. 2006;80: 802-815.
-
(2006)
J Leukoc Biol.
, vol.80
, pp. 802-815
-
-
Qualls, J.E.1
Kaplan, A.M.2
Van Rooijen, N.3
-
92
-
-
73449149272
-
Treatment with a novel chemokine-binding protein or eosinophil lineage-ablation protects mice from experimental colitis
-
Vieira AT, Fagundes CT, Alessandri AL, et al. Treatment with a novel chemokine-binding protein or eosinophil lineage-ablation protects mice from experimental colitis. Am J Pathol. 2009;175: 2382-2391.
-
(2009)
Am J Pathol.
, vol.175
, pp. 2382-2391
-
-
Vieira, A.T.1
Fagundes, C.T.2
Alessandri, A.L.3
-
93
-
-
52649176344
-
Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis
-
Lalli PN, Strainic MG, Yang M, et al. Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis. Blood. 2008;112:1759-1766.
-
(2008)
Blood
, vol.112
, pp. 1759-1766
-
-
Lalli, P.N.1
Strainic, M.G.2
Yang, M.3
-
94
-
-
78649482676
-
Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis
-
Langer HF, Chung KJ, Orlova VV, et al. Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis. Blood. 2010;116:4395-4403.
-
(2010)
Blood
, vol.116
, pp. 4395-4403
-
-
Langer, H.F.1
Chung, K.J.2
Orlova, V.V.3
-
95
-
-
84874623794
-
C5L2: A controversial receptor of complement anaphylatoxin, C5a
-
Li R, Coulthard LG, Wu M, et al. C5L2: a controversial receptor of complement anaphylatoxin, C5a. FASEB J. 2013;27:855-864.
-
(2013)
FASEB J.
, vol.27
, pp. 855-864
-
-
Li, R.1
Coulthard, L.G.2
Wu, M.3
-
96
-
-
84862589661
-
Complement-dependent injury and protection in a murine model of acute dextran sulfate sodiuminduced colitis
-
Schepp-Berglind J, Atkinson C, Elvington M, et al. Complement-dependent injury and protection in a murine model of acute dextran sulfate sodiuminduced colitis. J Immunol. 2012;188:6309-6318.
-
(2012)
J Immunol.
, vol.188
, pp. 6309-6318
-
-
Schepp-Berglind, J.1
Atkinson, C.2
Elvington, M.3
-
97
-
-
0035903289
-
C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells
-
Ogden CA, deCathelineau A, Hoffmann PR, et al. C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. J Exp Med. 2001;194: 781-795.
-
(2001)
J Exp Med.
, vol.194
, pp. 781-795
-
-
Ogden, C.A.1
Decathelineau, A.2
Hoffmann, P.R.3
|