Heat shock protein 70 is associated with CSFV NS5A protein and enhances viral RNA replication

Virology

Volumn 482, Issue , 2015, Pages 9-18

  Zhang, Chengcheng ^a   Kang, Kai ^a   Ning, Pengbo ^a   Peng, Yangxin ^a   Lin, Zhi ^a   Cui, Hongjie ^a   Cao, Zhi ^a   Wang, Jing ^a   Zhang, Yanming ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Classical swine fever virus (CSFV); HSP70; NS5A

Indexed keywords

HEAT SHOCK PROTEIN 70; LENTIVIRUS VECTOR; NONSTRUCTURAL PROTEIN 5A; VIRUS RNA; PROTEIN BINDING; VIRUS PROTEIN;

ARTICLE; CELLULAR DISTRIBUTION; CLASSICAL SWINE FEVER VIRUS; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GENE SILENCING; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA REPLICATION; VIRUS LOAD; VIRUS REPLICATION; CENTRIFUGATION; GENE DELETION; GENE EXPRESSION; HOST PATHOGEN INTERACTION; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN ANALYSIS;

CLASSICAL SWINE FEVER VIRUS; EUKARYOTA; LENTIVIRUS;

CENTRIFUGATION; CLASSICAL SWINE FEVER VIRUS; DNA MUTATIONAL ANALYSIS; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HOST-PATHOGEN INTERACTIONS; HSP70 HEAT-SHOCK PROTEINS; IMMUNOPRECIPITATION; MICROSCOPY, CONFOCAL; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; RNA, VIRAL; SEQUENCE DELETION; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84925840334     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2015.02.014     Document Type: Article

References (46)

1. Appel N., Zayas M., Miller S., Krijnse-Locker J., Schaller T., Friebe P., Kallis S., Engel U., Bartenschlager R. Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly. PLoS Pathog. 2008, 4:e1000035.
2. Bensaude E., Turner J.L., Wakeley P.R., Sweetman D.A., Pardieu C., Drew T.W., Wileman T., Powell P.P. Classical swine fever virus induces proinflammatory cytokines and tissue factor expression and inhibits apoptosis and interferon synthesis during the establishment of long-term infection of porcine vascular endothelial cells. J. Gen. Virol. 2004, 85:1029-1037.
3. Charleston B., Fray M., Baigent S., Carr B., Morrison W. Establishment of persistent infection with non-cytopathic bovine viral diarrhoea virus in cattle is associated with a failure to induce type I interferon. J. Gen. Virol. 2001, 82:1893-1897.
4. Chen Y., Xiao J., Sheng C., Wang J., Jia L., Zhi Y., Li G., Chen J., Xiao M. Classical swine fever virus NS5A regulates viral RNA replication through binding to NS5B and 3' UTR. Virology 2012, 432:376-388.
5. Chen Y.J., Chen Y.H., Chow L.P., Tsai Y.H., Chen P.H., Huang C.Y., Chen W.T., Hwang L.H. Heat shock protein 72 is associated with the hepatitis C virus replicase complex and enhances viral RNA replication. J. Biol. Chem. 2010, 285:28183-28190.
6. Cuthbert J.A. Hepatitis C: progress and problems. Clin. Microbiol. Rev. 1994, 7:505-532.
7. Frank D., Kuhn C., Katus H.A., Frey N. The sarcomeric Z-disc: a nodal point in signalling and disease. J. Mol. Med. 2006, 84:446-468.
8. Gonzalez O., Fontanes V., Raychaudhuri S., Loo R., Loo J., Arumugaswami V., Sun R., Dasgupta A., French S.W. The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production. Hepatology 2009, 50:1756-1764.
9. Hartl F.U., Hayer-Hartl M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 2002, 295:1852-1858.
10. He L., Zhang Y.M., Lin Z., Li W.W., Wang J., Li H.L. Classical swine fever virus NS5A protein localizes to endoplasmic reticulum and induces oxidative stress in vascular endothelial cells. Virus Genes 2012, 45:274-282.
11. He Y. The regulation of hepatitis C virus (HCV) internal ribosome-entry site-mediated translation by HCV replicons and nonstructural proteins. J. Gen. Virol. 2003, 84:535-543.
12. He Y., Yan W., Coito C., Li Y., Gale M., Katze M.G. The regulation of hepatitis C virus (HCV) internal ribosome-entry site-mediated translation by HCV replicons and nonstructural proteins. J. Gen. Virol. 2003, 84:535-543.
13. Isken O., Langerwisch U., Schonherr R., Lamp B., Schroder K., Duden R., Rumenapf T.H., Tautz N. Functional characterization of bovine viral diarrhea virus nonstructural protein 5A by reverse genetic analysis and live cell imaging. J. Virol. 2014, 88:82-98.
14. James P., Pfund C., Craig E.A. Functional specificity among Hsp70 molecular chaperones. Science 1997, 275:387-389.
15. Johns H.L., Bensaude E., La Rocca S.A., Seago J., Charleston B., Steinbach F., Drew T.W., Crooke H., Everett H. Classical swine fever virus infection protects aortic endothelial cells from pIpC-mediated apoptosis. J. Gen. Virol. 2010, 91:1038-1046.
16. Kalliampakou K.I., Kalamvoki M., Mavromara P. Hepatitis C virus (HCV) NS5A protein downregulates HCV IRES-dependent translation. J. Gen. Virol. 2005, 86:1015-1025.
17. Khachatoorian R., Ganapathy E., Ahmadieh Y., Wheatley N., Sundberg C., Jung C.-L., Arumugaswami V., Raychaudhuri S., Dasgupta A., French S.W. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology 2014, 454:118-127.
18. Kim M.Y., Shu Y., Carsillo T., Zhang J., Yu L., Peterson C., Longhi S., Girod S., Niewiesk S., Oglesbee M. hsp70 and a novel axis of Type I interferon-dependent antiviral immunity in the measles virus-infected brain. J. Virol. 2012, 87:998-1009.
19. Kleiboeker S.B. Swine fever: classical swine fever and African swine fever. Vet. Clin. North Am.: Food Anim. Pract. 2002, 18:431-451.
20. Lin Z., Liang W., Kang K., Li H., Cao Z., Zhang Y. Classical swine fever virus and p7 protein induce secretion of IL-1β in macrophages. J. Gen. Virol. 2014, 95:2693-2699.
21. Liu J., Bai J., Zhang L., Jiang Z., Wang X., Li Y., Jiang P. Hsp70 positively regulates porcine circovirus type 2 replication in vitro. Virology 2013, 447:52-62.
22. Mackowiak P.A. Physiological rationale for suppression of fever. Clin. Infect. Dis. 2000, 31:S185-S189.
23. Mayer M., Bukau B. Hsp70 chaperones: cellular functions and molecular mechanism. Cell. Mol. Life Sci. 2005, 62:670-684.
24. Moormann R.J., Bouma A., Kramps J.A., Terpstra C., De Smit H.J. Development of a classical swine fever subunit marker vaccine and companion diagnostic test. Vet. Microbiol. 2000, 73:209-219.
25. Nagy P., Wang R., Pogany J., Hafren A., Makinen K. Emerging picture of host chaperone and cyclophilin roles in RNA virus replication. Virology 2011, 411:374-382.
26. Ning P., Zhang Y., Guo K., Chen R., Liang W., Lin Z., Li H. Discovering up-regulated VEGF-C expression in swine umbilical vein endothelial cells by classical swine fever virus Shimen. Vet. Res. 2014, 45:48.
27. Okamoto T., Nishimura Y., Ichimura T., Suzuki K., Miyamura T., Suzuki T., Moriishi K., Matsuura Y. Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90. EMBO J. 2006, 25:5015-5025.
28. Parent R., Qu X., Petit M.A., Beretta L. The heat shock cognate protein 70 is associated with hepatitis C virus particles and modulates virus infectivity. Hepatology 2009, 49:1798-1809.
29. Pastorino B., Boucomont-Chapeaublanc E., Peyrefitte C.N., Belghazi M., Fusaï T., Rogier C., Tolou H.J., Almeras L. Identification of cellular proteome modifications in response to West Nile virus infection. Mol. Cell. Proteomics 2009, 8:1623-1637.
30. Pei J., Zhao M., Ye Z., Gou H., Wang J., Yi L., Dong X., Liu W., Luo Y., Liao M., Chen J. Autophagy enhances the replication of classical swine fever virus in vitro. Autophagy 2014, 10:93-110.
31. Rassow J., von Ahsen O., Bomer U., Pfanner N. Molecular chaperones: towards a characterization of the heat-shock protein 70 family. Trends Cell Biol. 1997, 7:129-133.
32. Schmittgen T.D., Livak K.J. Analyzing real-time PCR data by the comparative CT method. Nat. Protoc. 2008, 3:1101-1108.
33. Sheng C., Chen Y., Xiao J., Xiao J., Wang J., Li G., Chen J., Xiao M. Classical swine fever virus NS5A protein interacts with 3'-untranslated region and regulates viral RNA synthesis. Virus Res. 2012, 163:636-643.
34. Sheng C., Kou S., Jiang Q., Zhou C., Xiao J., Li J., Chen B., Zhao Y., Wang Y., Xiao M. Characterization of the c-terminal sequence of NS5A necessary for the assembly and production of classical swine fever virus infectious particles. Res. Vet. Sci. 2014, 97:449-454.
35. Sheng C., Wang J., Xiao J., Xiao J., Chen Y., Jia L., Zhi Y., Li G., Xiao M. Classical swine fever virus NS5B protein suppresses the inhibitory effect of NS5A on viral translation by binding to NS5A. J. Gen. Virol. 2012, 93:939-950.
36. Sheng C., Zhu Z., Yu J., Wan L., Wang Y., Chen J., Gu F., Xiao M. Characterization of NS3, NS5A and NS5B of classical swine fever virus through mutation and complementation analysis. Vet. Microbiol. 2010, 140:72-80.
37. Shi S.T., Polyak S.J., Tu H., Taylor D.R., Gretch D.R., Lai M. Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins. Virology 2002, 292:198-210.
38. Sullivan C.S., Pipas J.M. The virus-chaperone connection. Virology 2001, 287:1-8.
39. Tang Q., Guo K., Kang K., Zhang Y., He L., Wang J. Classical swine fever virus NS2 protein promotes interleukin-8 expression and inhibits MG132-induced apoptosis. Virus Genes 2011, 42:355-362.
40. Tang Q.H., Zhang Y.M., Fan L., Tong G., He L., Dai C. Classic swine fever virus NS2 protein leads to the induction of cell cycle arrest at S-phase and endoplasmic reticulum stress. Virol. J. 2010, 7:4.
41. Tellinghuisen T.L., Marcotrigiano J., Gorbalenya A.E., Rice C.M. The NS5A protein of hepatitis C virus is a zinc metalloprotein. J. Biol. Chem. 2004, 279:48576-48587.
42. Tellinghuisen T.L., Paulson M.S., Rice C.M. The NS5A protein of bovine viral diarrhea virus contains an essential zinc-binding site similar to that of the hepatitis C virus NS5A protein. J. Virol. 2006, 80:7450-7458.
43. Wang M., Grossmann M., Young C. Forced expression of heat-shock protein 70 increases the secretion of Hsp70 and provides protection against tumour growth. Br. J. Cancer 2004, 90:926-931.
44. Wu S.C., Chang S.C., Wu H.Y., Liao P.J., Chang M.F. Hepatitis C virus NS5A protein down-regulates the expression of spindle gene Aspm through PKR-p38 signaling pathway. J. Biol. Chem. 2008, 283:29396-29404.
45. Xiao M., Wang Y., Zhu Z., Yu J., Wan L., Chen J. Influence of NS5A protein of classical swine fever virus (CSFV) on CSFV internal ribosome entry site-dependent translation. J. Gen. Virol. 2009, 90:2923-2928.
46. Zhang C., He L., Kang K., Chen H., Xu L., Zhang Y. Screening of cellular proteins that interact with the classical swine fever virus non-structural protein 5A by yeast two-hybrid analysis. J. Biosci. 2014, 39:63-74.