메뉴 건너뛰기




Volumn 7, Issue 1, 2015, Pages

Principles and management of neuropsychiatric symptoms in Alzheimer's dementia

Author keywords

[No Author keywords available]

Indexed keywords

AMANTADINE; ANTICONVULSIVE AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; CITALOPRAM; DEXAMPHETAMINE; DONEPEZIL; METHYLPHENIDATE; MODAFINIL; MOOD STABILIZER; NEUROLEPTIC AGENT; OLANZAPINE; PLACEBO; QUETIAPINE; RISPERIDONE; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR;

EID: 84925834921     PISSN: None     EISSN: 17589193     Source Type: Journal    
DOI: 10.1186/s13195-015-0096-3     Document Type: Review
Times cited : (103)

References (109)
  • 1
    • 84910005783 scopus 로고    scopus 로고
    • Alzheimer's disease facts and figures
    • Alzheimer's Association. Alzheimer's disease facts and figures. Alzheimers Dement. 2014;2014:e47-92.
    • (2014) Alzheimers Dement , vol.2014 , pp. e47-e92
    • Alzheimer's Association1
  • 2
    • 77952771512 scopus 로고    scopus 로고
    • London: Alzheimer's Disease International
    • Prince M, Jackson J. World Alzheimer Report 2009. London: Alzheimer's Disease International; 2009 [http://www.alz.co.uk/research/files/WorldAlzheimerReport.pdf]
    • (2009) World Alzheimer Report 2009
    • Prince, M.1    Jackson, J.2
  • 4
    • 49049122193 scopus 로고    scopus 로고
    • Alzheimer's disease and vascular dementia in developing countries: Prevalence, management, and risk factors
    • Kalaria RN, Maestre GE, Arizaga R, Friedland RP, Galasko D, Hall K, et al. Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors. Lancet Neurol. 2008;7:812-26.
    • (2008) Lancet Neurol. , vol.7 , pp. 812-826
    • Kalaria, R.N.1    Maestre, G.E.2    Arizaga, R.3    Friedland, R.P.4    Galasko, D.5    Hall, K.6
  • 5
    • 77949336151 scopus 로고    scopus 로고
    • Alzheimer's disease facts and figures
    • Association A's. Alzheimer's disease facts and figures. Alzheimers Dement. 2010;2010:158-94.
    • (2010) Alzheimers Dement , vol.2010 , pp. 158-194
    • A's, A.1
  • 7
    • 79956076567 scopus 로고    scopus 로고
    • Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • Jack Jr CR, Albert MS, Knopman DS, McKhann GM, Sperling RA, Carrillo MC, et al. Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7:257-62.
    • (2011) Alzheimers Dement , vol.7 , pp. 257-262
    • Jack, C.R.1    Albert, M.S.2    Knopman, D.S.3    McKhann, G.M.4    Sperling, R.A.5    Carrillo, M.C.6
  • 8
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-44.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 9
    • 79956142378 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack Jr CR, Kawas CH, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7:263-9.
    • (2011) Alzheimers Dement , vol.7 , pp. 263-269
    • McKhann, G.M.1    Knopman, D.S.2    Chertkow, H.3    Hyman, B.T.4    Jack, C.R.5    Kawas, C.H.6
  • 10
  • 12
    • 0029165333 scopus 로고
    • The behavior rating scale for dementia of the consortium to establish a registry for Alzheimer's disease. The behavioral pathology committee of the consortium to establish a registry for Alzheimer's disease
    • Tariot PN, Mack JL, Patterson MB, Edland SD, Weiner MF, Fillenbaum G, et al. The Behavior Rating Scale for Dementia of the Consortium to Establish a Registry for Alzheimer's Disease. The Behavioral Pathology Committee of the Consortium to Establish a Registry for Alzheimer's Disease. Am J Psychiatry. 1995;152:1349-57.
    • (1995) Am J Psychiatry , vol.152 , pp. 1349-1357
    • Tariot, P.N.1    Mack, J.L.2    Patterson, M.B.3    Edland, S.D.4    Weiner, M.F.5    Fillenbaum, G.6
  • 15
    • 23044459469 scopus 로고    scopus 로고
    • The impact of neuropsychiatric symptoms of dementia on distress in family and professional caregivers in Singapore
    • Tan LL, Wong HB, Allen H. The impact of neuropsychiatric symptoms of dementia on distress in family and professional caregivers in Singapore. Int Psychogeriatr. 2005;17:253-63.
    • (2005) Int Psychogeriatr , vol.17 , pp. 253-263
    • Tan, L.L.1    Wong, H.B.2    Allen, H.3
  • 16
    • 65649127240 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms predict change in quality of life of Alzheimer disease patients: A two-year follow-up study
    • Tatsumi H, Nakaaki S, Torii K, Shinagawa Y, Watanabe N, Murata Y, et al. Neuropsychiatric symptoms predict change in quality of life of Alzheimer disease patients: a two-year follow-up study. Psychiatry Clin Neurosci. 2009;63:374-84.
    • (2009) Psychiatry Clin Neurosci , vol.63 , pp. 374-384
    • Tatsumi, H.1    Nakaaki, S.2    Torii, K.3    Shinagawa, Y.4    Watanabe, N.5    Murata, Y.6
  • 17
    • 0030958347 scopus 로고    scopus 로고
    • The Neuropsychiatric Inventory: Assessing psychopathology in dementia patients
    • Cummings JL. The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. Neurology. 1997;48:S10-6.
    • (1997) Neurology , vol.48 , pp. S10-S16
    • Cummings, J.L.1
  • 19
    • 77957319896 scopus 로고    scopus 로고
    • The Neuropsychiatric Inventory-Clinician rating scale (NPI-C): Reliability and validity of a revised assessment of neuropsychiatric symptoms in dementia
    • De Medeiros K, Robert P, Gauthier S, Stella F, Politis A, Leoutsakos J, et al. The Neuropsychiatric Inventory-Clinician rating scale (NPI-C): reliability and validity of a revised assessment of neuropsychiatric symptoms in dementia. Int Psychogeriatr. 2010;22:984-94.
    • (2010) Int Psychogeriatr , vol.22 , pp. 984-994
    • De Medeiros, K.1    Robert, P.2    Gauthier, S.3    Stella, F.4    Politis, A.5    Leoutsakos, J.6
  • 22
    • 84880164791 scopus 로고    scopus 로고
    • Subscale validation of the neuropsychiatric inventory questionnaire: Comparison of Alzheimer's disease neuroimaging initiative and national Alzheimer's coordinating center cohorts
    • Trzepacz PT, Saykin A, Yu P, Bhamditipati P, Sun J, Dennehy EB, et al. Subscale validation of the neuropsychiatric inventory questionnaire: comparison of Alzheimer's disease neuroimaging initiative and national Alzheimer's coordinating center cohorts. Am J Geriatr Psychiatry. 2013;21:607-22.
    • (2013) Am J Geriatr Psychiatry , vol.21 , pp. 607-622
    • Trzepacz, P.T.1    Saykin, A.2    Yu, P.3    Bhamditipati, P.4    Sun, J.5    Dennehy, E.B.6
  • 24
    • 84879972321 scopus 로고    scopus 로고
    • Behavioral and psychological subsyndromes in Alzheimer's disease using the Neuropsychiatric Inventory
    • Canevelli M, Adali N, Voisin T, Soto ME, Bruno G, Cesari M, et al. Behavioral and psychological subsyndromes in Alzheimer's disease using the Neuropsychiatric Inventory. Int J Geriatr Psychiatry. 2013;28:795-803.
    • (2013) Int J Geriatr Psychiatry , vol.28 , pp. 795-803
    • Canevelli, M.1    Adali, N.2    Voisin, T.3    Soto, M.E.4    Bruno, G.5    Cesari, M.6
  • 27
    • 36448966462 scopus 로고    scopus 로고
    • Neuropsychiatric syndromes in dementia. Results from the European Alzheimer Disease Consortium: Part I
    • Aalten P, Verhey FR, Boziki M, Bullock R, Byrne EJ, Camus V, et al. Neuropsychiatric syndromes in dementia. Results from the European Alzheimer Disease Consortium: part I. Dement Geriatr Cogn Disord. 2007;24:457-63.
    • (2007) Dement Geriatr Cogn Disord. , vol.24 , pp. 457-463
    • Aalten, P.1    Verhey, F.R.2    Boziki, M.3    Bullock, R.4    Byrne, E.J.5    Camus, V.6
  • 28
    • 79751478702 scopus 로고    scopus 로고
    • Grouping and trajectories of the neuropsychiatric symptoms in patients with Alzheimer's disease, part I: Symptom clusters
    • Garre-Olmo J, Lopez-Pousa S, Vilalta-Franch J, De Gracia BM, Vilarrasa AB. Grouping and trajectories of the neuropsychiatric symptoms in patients with Alzheimer's disease, part I: symptom clusters. J Alzheimers Dis. 2010;22:1157-67.
    • (2010) J Alzheimers Dis. , vol.22 , pp. 1157-1167
    • Garre-Olmo, J.1    Lopez-Pousa, S.2    Vilalta-Franch, J.3    De Gracia, B.M.4    Vilarrasa, A.B.5
  • 29
    • 33748417696 scopus 로고    scopus 로고
    • Four components describe behavioral symptoms in 1, 120 individuals with late-onset Alzheimer's disease
    • Hollingworth P, Hamshere ML, Moskvina V, Dowzell K, Moore PJ, Foy C, et al. Four components describe behavioral symptoms in 1, 120 individuals with late-onset Alzheimer's disease. J Am Geriatr Soc. 2006;54:1348-54.
    • (2006) J Am Geriatr Soc , vol.54 , pp. 1348-1354
    • Hollingworth, P.1    Hamshere, M.L.2    Moskvina, V.3    Dowzell, K.4    Moore, P.J.5    Foy, C.6
  • 30
    • 75549092013 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms in Korean patients with Alzheimer's disease: Exploratory factor analysis and confirmatory factor analysis of the neuropsychiatric inventory
    • Kang HS, Ahn IS, Kim JH, Kim DK. Neuropsychiatric symptoms in Korean patients with Alzheimer's disease: exploratory factor analysis and confirmatory factor analysis of the neuropsychiatric inventory. Dement Geriatr Cogn Disord. 2010;29:82-7.
    • (2010) Dement Geriatr Cogn Disord. , vol.29 , pp. 82-87
    • Kang, H.S.1    Ahn, I.S.2    Kim, J.H.3    Kim, D.K.4
  • 31
    • 78149282626 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms and syndromes in a large cohort of newly diagnosed, untreated patients with Alzheimer disease
    • Spalletta G, Musicco M, Padovani A, Rozzini L, Perri R, Fadda L, et al. Neuropsychiatric symptoms and syndromes in a large cohort of newly diagnosed, untreated patients with Alzheimer disease. Am J Geriatr Psychiatry. 2010;18:1026-35.
    • (2010) Am J Geriatr Psychiatry , vol.18 , pp. 1026-1035
    • Spalletta, G.1    Musicco, M.2    Padovani, A.3    Rozzini, L.4    Perri, R.5    Fadda, L.6
  • 32
    • 84863946456 scopus 로고    scopus 로고
    • Neuropsychiatric symptom clusters of Alzheimer's disease in Hong Kong Chinese: Prevalence and confirmatory factor analysis of the Neuropsychiatric Inventory
    • Cheng ST, Kwok T, Lam LC. Neuropsychiatric symptom clusters of Alzheimer's disease in Hong Kong Chinese: prevalence and confirmatory factor analysis of the Neuropsychiatric Inventory. Int Psychogeriatr. 2012;24:1465-73.
    • (2012) Int Psychogeriatr , vol.24 , pp. 1465-1473
    • Cheng, S.T.1    Kwok, T.2    Lam, L.C.3
  • 33
    • 77954230363 scopus 로고    scopus 로고
    • Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders
    • Insel T, Cuthbert B, Garvey M, Heinssen R, Pine DS, Quinn K, et al. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am J Psychiatry. 2010;167:748-51.
    • (2010) Am J Psychiatry , vol.167 , pp. 748-751
    • Insel, T.1    Cuthbert, B.2    Garvey, M.3    Heinssen, R.4    Pine, D.S.5    Quinn, K.6
  • 34
    • 26044465231 scopus 로고    scopus 로고
    • The rises and falls of disconnection syndromes
    • Catani M, Ffytche DH. The rises and falls of disconnection syndromes. Brain. 2005;128:2224-39.
    • (2005) Brain , vol.128 , pp. 2224-2239
    • Catani, M.1    Ffytche, D.H.2
  • 35
    • 84883557180 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms in Alzheimer's disease: Past progress and anticipation of the future
    • Geda YE, Schneider LS, Gitlin LN, Miller DS, Smith GS, Bell J, et al. Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future. Alzheimers Dement. 2013;9:602-8.
    • (2013) Alzheimers Dement , vol.9 , pp. 602-608
    • Geda, Y.E.1    Schneider, L.S.2    Gitlin, L.N.3    Miller, D.S.4    Smith, G.S.5    Bell, J.6
  • 36
    • 0027269660 scopus 로고
    • Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: Investigative and therapeutic perspectives
    • Francis PT, Sims NR, Procter AW, Bowen DM. Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: investigative and therapeutic perspectives. J Neurochem. 1993;60:1589-604.
    • (1993) J Neurochem , vol.60 , pp. 1589-1604
    • Francis, P.T.1    Sims, N.R.2    Procter, A.W.3    Bowen, D.M.4
  • 37
    • 62049083420 scopus 로고    scopus 로고
    • Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease
    • Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, et al. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nat Med. 2009;15:331-7.
    • (2009) Nat Med. , vol.15 , pp. 331-337
    • Nagahara, A.H.1    Merrill, D.A.2    Coppola, G.3    Tsukada, S.4    Schroeder, B.E.5    Shaked, G.M.6
  • 38
    • 77954179493 scopus 로고    scopus 로고
    • The putative neurodegenerative links between depression and Alzheimer's disease
    • Wuwongse S, Chang RC, Law AC. The putative neurodegenerative links between depression and Alzheimer's disease. Prog Neurobiol. 2010;91:362-75.
    • (2010) Prog Neurobiol. , vol.91 , pp. 362-375
    • Wuwongse, S.1    Chang, R.C.2    Law, A.C.3
  • 39
    • 79952490720 scopus 로고    scopus 로고
    • Differential involvement of hippocampal serotonin1A receptors and re-uptake sites in non-cognitive behaviors of Alzheimer's disease
    • Lai MK, Tsang SW, Esiri MM, Francis PT, Wong PT, Chen CP. Differential involvement of hippocampal serotonin1A receptors and re-uptake sites in non-cognitive behaviors of Alzheimer's disease. Psychopharmacology (Berl). 2011;213:431-9.
    • (2011) Psychopharmacology (Berl) , vol.213 , pp. 431-439
    • Lai, M.K.1    Tsang, S.W.2    Esiri, M.M.3    Francis, P.T.4    Wong, P.T.5    Chen, C.P.6
  • 40
    • 45249087489 scopus 로고    scopus 로고
    • Functional consequences of locus coeruleus degeneration in Alzheimer's disease
    • Weinshenker D. Functional consequences of locus coeruleus degeneration in Alzheimer's disease. Curr Alzheimer Res. 2008;5:342-5.
    • (2008) Curr Alzheimer Res. , vol.5 , pp. 342-345
    • Weinshenker, D.1
  • 41
    • 0037213050 scopus 로고    scopus 로고
    • Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: A meta-analysis
    • Lyness SA, Zarow C, Chui HC. Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysis. Neurobiol Aging. 2003;24:1-23.
    • (2003) Neurobiol Aging , vol.24 , pp. 1-23
    • Lyness, S.A.1    Zarow, C.2    Chui, H.C.3
  • 43
    • 33646084617 scopus 로고    scopus 로고
    • A study of the serotonin transporter in the prefrontal cortex in late-life depression and Alzheimer's disease with and without depression
    • Thomas AJ, Hendriksen M, Piggott M, Ferrier IN, Perry E, Ince P, et al. A study of the serotonin transporter in the prefrontal cortex in late-life depression and Alzheimer's disease with and without depression. Neuropathol Appl Neurobiol. 2006;32:296-303.
    • (2006) Neuropathol Appl Neurobiol. , vol.32 , pp. 296-303
    • Thomas, A.J.1    Hendriksen, M.2    Piggott, M.3    Ferrier, I.N.4    Perry, E.5    Ince, P.6
  • 45
    • 84855782970 scopus 로고    scopus 로고
    • Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease: A combined [11C]DASB and [18F]altanserin-PET study
    • Marner L, Frokjaer VG, Kalbitzer J, Lehel S, Madsen K, Baare WF, et al. Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease: a combined [11C]DASB and [18F]altanserin-PET study. Neurobiol Aging. 2012;33:479-87.
    • (2012) Neurobiol Aging , vol.33 , pp. 479-487
    • Marner, L.1    Frokjaer, V.G.2    Kalbitzer, J.3    Lehel, S.4    Madsen, K.5    Baare, W.F.6
  • 46
    • 0034727605 scopus 로고    scopus 로고
    • Cholinergic deficits contribute to behavioral disturbance in patients with dementia
    • Minger SL, Esiri MM, McDonald B, Keene J, Carter J, Hope T, et al. Cholinergic deficits contribute to behavioral disturbance in patients with dementia. Neurology. 2000;55:1460-7.
    • (2000) Neurology , vol.55 , pp. 1460-1467
    • Minger, S.L.1    Esiri, M.M.2    McDonald, B.3    Keene, J.4    Carter, J.5    Hope, T.6
  • 50
    • 33745850468 scopus 로고    scopus 로고
    • Frontal dysfunction underlies depressive syndrome in Alzheimer disease: A FDG-PET study
    • Lee DY, Choo IH, Jhoo JH, Kim KW, Youn JC, Lee DS, et al. Frontal dysfunction underlies depressive syndrome in Alzheimer disease: a FDG-PET study. Am J Geriatr Psychiatry. 2006;14:625-8.
    • (2006) Am J Geriatr Psychiatry , vol.14 , pp. 625-628
    • Lee, D.Y.1    Choo, I.H.2    Jhoo, J.H.3    Kim, K.W.4    Youn, J.C.5    Lee, D.S.6
  • 52
    • 68249152023 scopus 로고    scopus 로고
    • Altered brain serotonin transporter and associated glucose metabolism in Alzheimer disease
    • Ouchi Y, Yoshikawa E, Futatsubashi M, Yagi S, Ueki T, Nakamura K. Altered brain serotonin transporter and associated glucose metabolism in Alzheimer disease. J Nucl Med. 2009;50:1260-6.
    • (2009) J Nucl Med. , vol.50 , pp. 1260-1266
    • Ouchi, Y.1    Yoshikawa, E.2    Futatsubashi, M.3    Yagi, S.4    Ueki, T.5    Nakamura, K.6
  • 53
    • 84876778919 scopus 로고    scopus 로고
    • Recent advances in neuroimaging biomarkers in geriatric psychiatry
    • Khandai AC, Aizenstein HJ. Recent advances in neuroimaging biomarkers in geriatric psychiatry. Curr Psychiatry Rep. 2013;15:360.
    • (2013) Curr Psychiatry Rep , vol.15 , pp. 360
    • Khandai, A.C.1    Aizenstein, H.J.2
  • 54
    • 84893562851 scopus 로고    scopus 로고
    • Positron emission tomography molecular imaging in late-life depression
    • Hirao K, Smith GS. Positron emission tomography molecular imaging in late-life depression. J Geriatr Psychiatry Neurol. 2014;27:13-23.
    • (2014) J Geriatr Psychiatry Neurol. , vol.27 , pp. 13-23
    • Hirao, K.1    Smith, G.S.2
  • 55
    • 37249066622 scopus 로고    scopus 로고
    • Striatal dopamine transporter levels correlate with apathy in neurodegenerative diseases A SPECT study with partial volume effect correction
    • David R, Koulibaly M, Benoit M, Garcia R, Caci H, Darcourt J, et al. Striatal dopamine transporter levels correlate with apathy in neurodegenerative diseases A SPECT study with partial volume effect correction. Clin Neurol Neurosurg. 2008;110:19-24.
    • (2008) Clin Neurol Neurosurg , vol.110 , pp. 19-24
    • David, R.1    Koulibaly, M.2    Benoit, M.3    Garcia, R.4    Caci, H.5    Darcourt, J.6
  • 56
    • 84928008851 scopus 로고    scopus 로고
    • Cholinergic receptor imaging in Alzheimer's disease: Method and early results, in Annual Meeting of the American Association for Geriatric Psychiatry
    • Sultzer DL, Melrose R, Campa OR, Achamallah N, Harwood D, Brody A, et al. Cholinergic receptor imaging in Alzheimer's disease: method and early results, in Annual Meeting of the American Association for Geriatric Psychiatry. Am J Geriatr Psychiatry. 2010;18:S71-2.
    • (2010) Am J Geriatr Psychiatry , vol.18 , pp. S71-S72
    • Sultzer, D.L.1    Melrose, R.2    Campa, O.R.3    Achamallah, N.4    Harwood, D.5    Brody, A.6
  • 59
    • 4043174258 scopus 로고    scopus 로고
    • Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease
    • Assal F, Alarcon M, Solomon EC, Masterman D, Geschwind DH, Cummings JL. Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease. Arch Neurol. 2004;61:1249-53.
    • (2004) Arch Neurol. , vol.61 , pp. 1249-1253
    • Assal, F.1    Alarcon, M.2    Solomon, E.C.3    Masterman, D.4    Geschwind, D.H.5    Cummings, J.L.6
  • 61
    • 50849127099 scopus 로고    scopus 로고
    • Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease
    • Bruen PD, McGeown WJ, Shanks MF, Venneri A. Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease. Brain. 2008;131:2455-63.
    • (2008) Brain , vol.131 , pp. 2455-2463
    • Bruen, P.D.1    McGeown, W.J.2    Shanks, M.F.3    Venneri, A.4
  • 62
    • 84885593174 scopus 로고    scopus 로고
    • Frontolimbic atrophy is associated with agitation and aggression in mild cognitive impairment and Alzheimer's disease
    • e101
    • Trzepacz PT, Yu P, Bhamidipati PK, Willis B, Forrester T, Tabas L, et al. Frontolimbic atrophy is associated with agitation and aggression in mild cognitive impairment and Alzheimer's disease. Alzheimers Dement. 2013;9:S95-104. e101.
    • (2013) Alzheimers Dement , vol.9 , pp. S95-S104
    • Trzepacz, P.T.1    Yu, P.2    Bhamidipati, P.K.3    Willis, B.4    Forrester, T.5    Tabas, L.6
  • 63
    • 62149141359 scopus 로고    scopus 로고
    • Increased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer disease
    • Reeves S, Brown R, Howard R, Grasby P. Increased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer disease. Neurology. 2009;72:528-34.
    • (2009) Neurology , vol.72 , pp. 528-534
    • Reeves, S.1    Brown, R.2    Howard, R.3    Grasby, P.4
  • 66
    • 62749122900 scopus 로고    scopus 로고
    • Regionally-specific diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease
    • Mielke MM, Kozauer NA, Chan KC, George M, Toroney J, Zerrate M, et al. Regionally-specific diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease. Neuroimage. 2009;46:47-55.
    • (2009) Neuroimage , vol.46 , pp. 47-55
    • Mielke, M.M.1    Kozauer, N.A.2    Chan, K.C.3    George, M.4    Toroney, J.5    Zerrate, M.6
  • 67
    • 84896394685 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms in Alzheimer's disease are related to functional connectivity alterations in the salience network
    • Balthazar ML, Pereira FR, Lopes TM, Da Silva EL, Coan AC, Campos BM, et al. Neuropsychiatric symptoms in Alzheimer's disease are related to functional connectivity alterations in the salience network. Hum Brain Mapp. 2014;35:1237-46.
    • (2014) Hum Brain Mapp , vol.35 , pp. 1237-1246
    • Balthazar, M.L.1    Pereira, F.R.2    Lopes, T.M.3    Da Silva, E.L.4    Coan, A.C.5    Campos, B.M.6
  • 68
    • 85027950875 scopus 로고    scopus 로고
    • Saliency, switching, attention and control: A network model of insula function
    • Menon V, Uddin LQ. Saliency, switching, attention and control: a network model of insula function. Brain Struct Funct. 2010;214:655-67.
    • (2010) Brain Struct Funct , vol.214 , pp. 655-667
    • Menon, V.1    Uddin, L.Q.2
  • 70
  • 72
    • 0028469704 scopus 로고
    • Neuropathological correlates of psychotic phenomena in confirmed Alzheimer's disease
    • Forstl H, Burns A, Levy R, Cairns N. Neuropathological correlates of psychotic phenomena in confirmed Alzheimer's disease. Br J Psychiatry. 1994;165:53-9.
    • (1994) Br J Psychiatry , vol.165 , pp. 53-59
    • Forstl, H.1    Burns, A.2    Levy, R.3    Cairns, N.4
  • 73
    • 84896730844 scopus 로고    scopus 로고
    • Neural basis of three dimensions of agitated behaviors in patients with Alzheimer disease
    • Banno K, Nakaaki S, Sato J, Torii K, Narumoto J, Miyata J, et al. Neural basis of three dimensions of agitated behaviors in patients with Alzheimer disease. Neuropsychiatr Dis Treat. 2014;10:339-48.
    • (2014) Neuropsychiatr Dis Treat , vol.10 , pp. 339-348
    • Banno, K.1    Nakaaki, S.2    Sato, J.3    Torii, K.4    Narumoto, J.5    Miyata, J.6
  • 76
    • 0028966748 scopus 로고
    • Contributions of anterior cingulate cortex to behaviour
    • Devinsky O, Morrell MJ, Vogt BA. Contributions of anterior cingulate cortex to behaviour. Brain. 1995;118:279-306.
    • (1995) Brain , vol.118 , pp. 279-306
    • Devinsky, O.1    Morrell, M.J.2    Vogt, B.A.3
  • 77
    • 0034986909 scopus 로고    scopus 로고
    • The anterior cingulate cortex: The evolution of an interface between emotion and cognition
    • Allman JM, Hakeem A, Erwin JM, Nimchinsky E, Hof P. The anterior cingulate cortex: the evolution of an interface between emotion and cognition. Ann NYAcad Sci. 2001;935:107-17.
    • (2001) Ann N Y Acad Sci. , vol.935 , pp. 107-117
    • Allman, J.M.1    Hakeem, A.2    Erwin, J.M.3    Nimchinsky, E.4    Hof, P.5
  • 78
    • 84874586932 scopus 로고    scopus 로고
    • Effect of selective serotonin reuptake inhibitors in Alzheimer's disease with comorbid depression: A meta-analysis of depression and cognitive outcomes
    • Sepehry AA, Lee PE, Hsiung GY, Beattie BL, Jacova C. Effect of selective serotonin reuptake inhibitors in Alzheimer's disease with comorbid depression: a meta-analysis of depression and cognitive outcomes. Drugs Aging. 2012;29:793-806.
    • (2012) Drugs Aging , vol.29 , pp. 793-806
    • Sepehry, A.A.1    Lee, P.E.2    Hsiung, G.Y.3    Beattie, B.L.4    Jacova, C.5
  • 79
    • 84904819200 scopus 로고    scopus 로고
    • Comparison of sertraline, venlafaxine and desipramine effects on depression, cognition and the daily living activities in Alzheimer patients
    • Mokhber N, Abdollahian E, Soltanifar A, Samadi R, Saghebi A, Haghighi MB, et al. Comparison of sertraline, venlafaxine and desipramine effects on depression, cognition and the daily living activities in Alzheimer patients. Pharmacopsychiatry. 2014;47:131-40.
    • (2014) Pharmacopsychiatry , vol.47 , pp. 131-140
    • Mokhber, N.1    Abdollahian, E.2    Soltanifar, A.3    Samadi, R.4    Saghebi, A.5    Haghighi, M.B.6
  • 81
    • 84880141783 scopus 로고    scopus 로고
    • Designing a trial to evaluate potential treatments for apathy in dementia: The apathy in dementia methylphenidate trial (ADMET)
    • Drye LT, Scherer RW, Lanctot KL, Rosenberg PB, Herrmann N, Bachman D, et al. Designing a trial to evaluate potential treatments for apathy in dementia: the apathy in dementia methylphenidate trial (ADMET). Am J Geriatr Psychiatry. 2013;21:549-59.
    • (2013) Am J Geriatr Psychiatry , vol.21 , pp. 549-559
    • Drye, L.T.1    Scherer, R.W.2    Lanctot, K.L.3    Rosenberg, P.B.4    Herrmann, N.5    Bachman, D.6
  • 82
    • 84883176211 scopus 로고    scopus 로고
    • Safety and efficacy of methylphenidate for apathy in Alzheimer's disease: A randomized, placebo-controlled trial
    • Rosenberg PB, Lanctot KL, Drye LT, Herrmann N, Scherer RW, Bachman DL, et al. Safety and efficacy of methylphenidate for apathy in Alzheimer's disease: a randomized, placebo-controlled trial. J Clin Psychiatry. 2013;74:810-6.
    • (2013) J Clin Psychiatry , vol.74 , pp. 810-816
    • Rosenberg, P.B.1    Lanctot, K.L.2    Drye, L.T.3    Herrmann, N.4    Scherer, R.W.5    Bachman, D.L.6
  • 83
    • 84892157086 scopus 로고    scopus 로고
    • Effect of methylphenidate on attention in apathetic AD patients in a randomized, placebo-controlled trial
    • Lanctot KL, Chau SA, Herrmann N, Drye LT, Rosenberg PB, Scherer RW, et al. Effect of methylphenidate on attention in apathetic AD patients in a randomized, placebo-controlled trial. Int Psychogeriatr. 2014;26:239-46.
    • (2014) Int Psychogeriatr , vol.26 , pp. 239-246
    • Lanctot, K.L.1    Chau, S.A.2    Herrmann, N.3    Drye, L.T.4    Rosenberg, P.B.5    Scherer, R.W.6
  • 84
    • 51449084071 scopus 로고    scopus 로고
    • Methylphenidate for the treatment of apathy in Alzheimer disease: Prediction of response using dextroamphetamine challenge
    • Herrmann N, Rothenburg LS, Black SE, Ryan M, Liu BA, Busto UE, et al. Methylphenidate for the treatment of apathy in Alzheimer disease: prediction of response using dextroamphetamine challenge. J Clin Psychopharmacol. 2008;28:296-301.
    • (2008) J Clin Psychopharmacol. , vol.28 , pp. 296-301
    • Herrmann, N.1    Rothenburg, L.S.2    Black, S.E.3    Ryan, M.4    Liu, B.A.5    Busto, U.E.6
  • 87
    • 0024327203 scopus 로고
    • Amantadine and the end-stage dementia of Alzheimer's type
    • Erkulwater S, Pillai R. Amantadine and the end-stage dementia of Alzheimer's type. South Med J. 1989;82:550-4.
    • (1989) South Med J , vol.82 , pp. 550-554
    • Erkulwater, S.1    Pillai, R.2
  • 89
    • 84863548826 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of modafinil for the treatment of apathy in individuals with mild-to-moderate Alzheimer's disease
    • Frakey LL, Salloway S, Buelow M, Malloy P. A randomized, double-blind, placebo-controlled trial of modafinil for the treatment of apathy in individuals with mild-to-moderate Alzheimer's disease. J Clin Psychiatry. 2012;73:796-801.
    • (2012) J Clin Psychiatry , vol.73 , pp. 796-801
    • Frakey, L.L.1    Salloway, S.2    Buelow, M.3    Malloy, P.4
  • 90
  • 91
    • 58149236875 scopus 로고    scopus 로고
    • Use of antipsychotics in elderly patients with dementia: Do atypical and conventional agents have a similar safety profile?
    • Trifirò G, Spina E, Gambassi G. Use of antipsychotics in elderly patients with dementia: do atypical and conventional agents have a similar safety profile? Pharmacol Res. 2009;59:1-12.
    • (2009) Pharmacol Res. , vol.59 , pp. 1-12
    • Trifirò, G.1    Spina, E.2    Gambassi, G.3
  • 92
    • 26844538114 scopus 로고    scopus 로고
    • Risk of death with atypical antipsychotic drug treatment for dementia: Meta-analysis of randomized placebo-controlled trials
    • Schneider LS, Dagerman KS, Insel P. Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials. JAMA. 2005;294:1934-43.
    • (2005) JAMA , vol.294 , pp. 1934-1943
    • Schneider, L.S.1    Dagerman, K.S.2    Insel, P.3
  • 93
    • 46749095495 scopus 로고    scopus 로고
    • Clinical symptom responses to atypical antipsychotic medications in Alzheimer's disease: Phase 1 outcomes from the CATIE-AD effectiveness trial
    • Sultzer DL, Davis SM, Tariot PN, Dagerman KS, Lebowitz BD, Lyketsos CG, et al. Clinical symptom responses to atypical antipsychotic medications in Alzheimer's disease: phase 1 outcomes from the CATIE-AD effectiveness trial. Am J Psychiatry. 2008;165:844-54.
    • (2008) Am J Psychiatry , vol.165 , pp. 844-854
    • Sultzer, D.L.1    Davis, S.M.2    Tariot, P.N.3    Dagerman, K.S.4    Lebowitz, B.D.5    Lyketsos, C.G.6
  • 95
    • 84883693104 scopus 로고    scopus 로고
    • The long-term effects of conventional and atypical antipsychotics in patients with probable Alzheimer's disease
    • Lopez OL, Becker JT, Chang YF, Sweet RA, Aizenstein H, Snitz B, et al. The long-term effects of conventional and atypical antipsychotics in patients with probable Alzheimer's disease. Am J Psychiatry. 2013;170:1051-8.
    • (2013) Am J Psychiatry , vol.170 , pp. 1051-1058
    • Lopez, O.L.1    Becker, J.T.2    Chang, Y.F.3    Sweet, R.A.4    Aizenstein, H.5    Snitz, B.6
  • 96
    • 43349091168 scopus 로고    scopus 로고
    • Early frontal executive impairment as a predictor of subsequent behavior disturbance in dementia
    • Tsoi T, Baillon S, Lindesay J. Early frontal executive impairment as a predictor of subsequent behavior disturbance in dementia. Am J Geriatr Psychiatry. 2008;16:102-8.
    • (2008) Am J Geriatr Psychiatry , vol.16 , pp. 102-108
    • Tsoi, T.1    Baillon, S.2    Lindesay, J.3
  • 97
    • 2442542158 scopus 로고    scopus 로고
    • Forgotten frontal lobe syndrome or 'Executive Dysfunction Syndrome'
    • Lyketsos CG, Rosenblatt A, Rabins P. Forgotten frontal lobe syndrome or 'Executive Dysfunction Syndrome'. Psychosomatics. 2004;45:247-55.
    • (2004) Psychosomatics , vol.45 , pp. 247-255
    • Lyketsos, C.G.1    Rosenblatt, A.2    Rabins, P.3
  • 98
    • 22144463792 scopus 로고    scopus 로고
    • Neuropsychological functioning of dementia patients with psychosis
    • Hopkins MW, Libon DJ. Neuropsychological functioning of dementia patients with psychosis. Arch Clin Neuropsychol. 2005;20:771-83.
    • (2005) Arch Clin Neuropsychol. , vol.20 , pp. 771-783
    • Hopkins, M.W.1    Libon, D.J.2
  • 100
    • 84894122063 scopus 로고    scopus 로고
    • Effect of citalopram on agitation in Alzheimer disease: The CitAD randomized clinical trial
    • Porsteinsson AP, Drye LT, Pollock BG, Devanand DP, Frangakis C, Ismail Z, et al. Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial. JAMA. 2014;311:682-91.
    • (2014) JAMA , vol.311 , pp. 682-691
    • Porsteinsson, A.P.1    Drye, L.T.2    Pollock, B.G.3    Devanand, D.P.4    Frangakis, C.5    Ismail, Z.6
  • 102
    • 0030994602 scopus 로고    scopus 로고
    • Effect of amantadine hydrochloride on symptoms of frontal lobe dysfunction in brain injury: Case studies and review
    • Kraus MF, Maki PM. Effect of amantadine hydrochloride on symptoms of frontal lobe dysfunction in brain injury: case studies and review. J Neuropsychiatry Clin Neurosci. 1997;9:222-30.
    • (1997) J Neuropsychiatry Clin Neurosci , vol.9 , pp. 222-230
    • Kraus, M.F.1    Maki, P.M.2
  • 103
  • 104
    • 38949131833 scopus 로고    scopus 로고
    • Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: A literature review
    • Konovalov S, Muralee S, Tampi RR. Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review. Int Psychogeriatr. 2008;20:293-308.
    • (2008) Int Psychogeriatr , vol.20 , pp. 293-308
    • Konovalov, S.1    Muralee, S.2    Tampi, R.R.3
  • 105
    • 84864125825 scopus 로고    scopus 로고
    • Impact of treatment with acetylcholinesterase inhibitors, valproic acid and antipsychotics on aggressive behaviour in Alzheimer's type dementia [in Polish]
    • Bidzan L, Grabowski J, Dutczak B, Bidzan M. Impact of treatment with acetylcholinesterase inhibitors, valproic acid and antipsychotics on aggressive behaviour in Alzheimer's type dementia [in Polish]. Psychiatr Pol. 2012;46:361-72.
    • (2012) Psychiatr Pol. , vol.46 , pp. 361-372
    • Bidzan, L.1    Grabowski, J.2    Dutczak, B.3    Bidzan, M.4
  • 106
    • 27744488144 scopus 로고    scopus 로고
    • Systematic review of psychological approaches to the management of neuropsychiatric symptoms of dementia
    • Livingston G, Johnston K, Katona C, Paton J, Lyketsos CG. Systematic review of psychological approaches to the management of neuropsychiatric symptoms of dementia. Am J Psychiatry. 2005;162:1996-2021.
    • (2005) Am J Psychiatry , vol.162 , pp. 1996-2021
    • Livingston, G.1    Johnston, K.2    Katona, C.3    Paton, J.4    Lyketsos, C.G.5
  • 107
    • 0035145320 scopus 로고    scopus 로고
    • Functional analysis of challenging behaviour in dementia: The role of superstition
    • Moniz-Cook E, Woods RT, Richards K. Functional analysis of challenging behaviour in dementia: the role of superstition. Int J Geriatr Psychiatry. 2001;16:45-56.
    • (2001) Int J Geriatr Psychiatry , vol.16 , pp. 45-56
    • Moniz-Cook, E.1    Woods, R.T.2    Richards, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.