The tyrosine phosphatase SHP-1 regulates hypoxia inducible factor-1α (HIF-1α) protein levels in endothelial cells under hypoxia

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Alig, Stefan K ^a,b   Stampnik, Yvonn ^a   Pircher, Joachim ^a,b   Rotter, Raffaela ^a   Gaitzsch, Erik ^a   Ribeiro, Andrea ^b   Wörnle, Markus ^b   Krötz, Florian ^c   Mannell, Hanna ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c Interventional Cardiology Starnberg Community Hospital   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; APIGENIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DICHLOROFLUORESCEIN; ECHINOMYCIN; HYDROETHIDINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PROTEASOME; PROTEIN TYROSINE PHOSPHATASE SHP 1; REACTIVE OXYGEN METABOLITE; VASCULOTROPIN; HIF1A PROTEIN, HUMAN; PTPN6 PROTEIN, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL LEVEL; CONTROLLED STUDY; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME ACTIVITY; FLUORESCENCE ANALYSIS; GENE OVEREXPRESSION; GENE SILENCING; HALF LIFE TIME; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; OXIDATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; WILD TYPE; CELL HYPOXIA; CELL PROLIFERATION; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS);

CELL HYPOXIA; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; REACTIVE OXYGEN SPECIES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84925763564     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0121113     Document Type: Article

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