-
2
-
-
74749089537
-
Systemic therapy in recurrent ovarian cancer: current treatment options and new drugs
-
COI: 1:CAS:528:DC%2BD1MXhsFKns7%2FM, PID: 20014888
-
Harter P, Hilpert F, Mahner S, Heitz F, Pfisterer J, du Bois A. Systemic therapy in recurrent ovarian cancer: current treatment options and new drugs. Expert Rev Anticancer Ther. 2010;10:81–8.
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, pp. 81-88
-
-
Harter, P.1
Hilpert, F.2
Mahner, S.3
Heitz, F.4
Pfisterer, J.5
du Bois, A.6
-
3
-
-
84855425106
-
Gynecologic Oncology Group Incorporation of bevacizumab in the primary treatment of ovarian cancer
-
COI: 1:CAS:528:DC%2BC38XktVWhsg%3D%3D, PID: 22204724
-
Burger RA, Brady MF, Bookman MA, Fleming GF, Monk BJ, Huang H, et al. Gynecologic Oncology Group Incorporation of bevacizumab in the primary treatment of ovarian cancer. N Engl J Med. 2011;365:2473–83.
-
(2011)
N Engl J Med
, vol.365
, pp. 2473-2483
-
-
Burger, R.A.1
Brady, M.F.2
Bookman, M.A.3
Fleming, G.F.4
Monk, B.J.5
Huang, H.6
-
4
-
-
84855466019
-
A phase 3 trial of bevacizumab in ovarian cancer
-
COI: 1:CAS:528:DC%2BC38XktVWltA%3D%3D, PID: 22204725
-
Perren TJ, Swart AM, Pfisterer J, Ledermann JA, Pujade-Lauraine E, Kristensen G, et al. A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med. 2011;365:2484–96.
-
(2011)
N Engl J Med
, vol.365
, pp. 2484-2496
-
-
Perren, T.J.1
Swart, A.M.2
Pfisterer, J.3
Ledermann, J.A.4
Pujade-Lauraine, E.5
Kristensen, G.6
-
5
-
-
84925821086
-
TGFβ and matrix-regulated epithelial to mesenchymal transition
-
Moustakas A, Heldin P. TGFβ and matrix-regulated epithelial to mesenchymal transition. Biochim Biophys Acta. 1840;2014:2621–34.
-
(1840)
Biochim Biophys Acta
, vol.2014
, pp. 2621-2634
-
-
Moustakas, A.1
Heldin, P.2
-
6
-
-
84894593599
-
Molecular mechanisms of epithelial-mesenchymal transition
-
COI: 1:CAS:528:DC%2BC2cXivFagtrY%3D, PID: 24556840
-
Lamouille S, Xu J, Derynck R. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2014;15:178–96.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 178-196
-
-
Lamouille, S.1
Xu, J.2
Derynck, R.3
-
7
-
-
84887273608
-
Epithelial plasticity: a common theme in embryonic and cancer cells
-
PID: 24202173
-
Nieto MA. Epithelial plasticity: a common theme in embryonic and cancer cells. Science. 2013;342:1234850.
-
(2013)
Science
, vol.342
, pp. 1234850
-
-
Nieto, M.A.1
-
8
-
-
84890828010
-
Regulation of EMT by Notch signaling pathway in tumor progression
-
COI: 1:CAS:528:DC%2BC2cXit12gsA%3D%3D, PID: 24168187
-
Li Y, Ma J, Qian X, Wu Q, Xia J, Miele L, et al. Regulation of EMT by Notch signaling pathway in tumor progression. Curr Cancer Drug Targets. 2013;13:957–62.
-
(2013)
Curr Cancer Drug Targets
, vol.13
, pp. 957-962
-
-
Li, Y.1
Ma, J.2
Qian, X.3
Wu, Q.4
Xia, J.5
Miele, L.6
-
9
-
-
84880698825
-
The role of endocytic pathways in TGF-β signaling
-
COI: 1:CAS:528:DC%2BC3sXmt1Cit7g%3D, PID: 23274761
-
Balogh P, Katz S, Kiss AL. The role of endocytic pathways in TGF-β signaling. Pathol Oncol Res. 2013;19:141–8.
-
(2013)
Pathol Oncol Res
, vol.19
, pp. 141-148
-
-
Balogh, P.1
Katz, S.2
Kiss, A.L.3
-
10
-
-
84866334922
-
TGF-β-induced epithelial-mesenchymal transition: a link between cancer and inflammation
-
COI: 1:CAS:528:DC%2BC38XhtlOju7bL, PID: 22627188
-
Fuxe J, Karlsson MC. TGF-β-induced epithelial-mesenchymal transition: a link between cancer and inflammation. Semin Cancer Biol. 2012;22:455–61.
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 455-461
-
-
Fuxe, J.1
Karlsson, M.C.2
-
11
-
-
84867115486
-
Microenvironmental regulation of epithelial-mesenchymal transitions in cancer
-
COI: 1:CAS:528:DC%2BC38XhsVOqtLjM, PID: 23002209
-
Gao D, Vahdat LT, Wong S, Chang JC, Mittal V. Microenvironmental regulation of epithelial-mesenchymal transitions in cancer. Cancer Res. 2012;72:4883–9.
-
(2012)
Cancer Res
, vol.72
, pp. 4883-4889
-
-
Gao, D.1
Vahdat, L.T.2
Wong, S.3
Chang, J.C.4
Mittal, V.5
-
12
-
-
84856015098
-
Epithelial-mesenchymal transition, cancer stem cells and treatment resistance
-
PID: 22264257
-
Dave B, Mittal V, Tan NM, Chang JC. Epithelial-mesenchymal transition, cancer stem cells and treatment resistance. Breast Cancer Res. 2012;14:202.
-
(2012)
Breast Cancer Res
, vol.14
, pp. 202
-
-
Dave, B.1
Mittal, V.2
Tan, N.M.3
Chang, J.C.4
-
13
-
-
84901387582
-
Chemokines and chemokine receptors: update on utility and challenges for the clinician
-
PID: 24856117
-
Roy I, Evans DB, Dwinell MB. Chemokines and chemokine receptors: update on utility and challenges for the clinician. Surgery. 2014;155:961–73.
-
(2014)
Surgery
, vol.155
, pp. 961-973
-
-
Roy, I.1
Evans, D.B.2
Dwinell, M.B.3
-
14
-
-
84883330287
-
Chemokine receptors as therapeutic targets
-
COI: 1:CAS:528:DC%2BC3sXhslWhsL7I, PID: 23994796
-
Yoshie O. Chemokine receptors as therapeutic targets. Nihon Rinsho Meneki Gakkai Kaishi. 2013;36:189–96.
-
(2013)
Nihon Rinsho Meneki Gakkai Kaishi
, vol.36
, pp. 189-196
-
-
Yoshie, O.1
-
15
-
-
10744226186
-
Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma
-
COI: 1:CAS:528:DC%2BD3sXotFCktr4%3D, PID: 12960129
-
Ding Y, Shimada Y, Maeda M, Kawabe A, Kaganoi J, Komoto I, et al. Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma. Clin Cancer Res. 2003;9:3406–12.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3406-3412
-
-
Ding, Y.1
Shimada, Y.2
Maeda, M.3
Kawabe, A.4
Kaganoi, J.5
Komoto, I.6
-
16
-
-
0037431546
-
Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis
-
COI: 1:CAS:528:DC%2BD3sXjt12mtrw%3D, PID: 12673677
-
Takanami I. Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis. Int J Cancer. 2003;105:186–9.
-
(2003)
Int J Cancer
, vol.105
, pp. 186-189
-
-
Takanami, I.1
-
17
-
-
1642290776
-
Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype
-
COI: 1:CAS:528:DC%2BD2cXhslersrg%3D, PID: 14996750
-
Wang J, Xi L, Hunt JL, Gooding W, Whiteside TL, Chen Z, et al. Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype. Cancer Res. 2004;64:1861–6.
-
(2004)
Cancer Res
, vol.64
, pp. 1861-1866
-
-
Wang, J.1
Xi, L.2
Hunt, J.L.3
Gooding, W.4
Whiteside, T.L.5
Chen, Z.6
-
18
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
PID: 11242036
-
Müller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature. 2001;410:50–6.
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Müller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
-
19
-
-
0037614262
-
Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells
-
Aliaga JC, Deschênes C, Beaulieu JF, Calvo EL, Rivard N. Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells. Am J Physiol. 1999;277:631–41.
-
(1999)
Am J Physiol
, vol.277
, pp. 631-641
-
-
Aliaga, J.C.1
Deschênes, C.2
Beaulieu, J.F.3
Calvo, E.L.4
Rivard, N.5
-
20
-
-
0032928614
-
Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human
-
COI: 1:CAS:528:DyaK1MXhs1Cgu7s%3D, PID: 9922370
-
Widmann C, Gibson S, Jarpe MB, Johnson GL. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol Rev. 1999;79:143–80.
-
(1999)
Physiol Rev
, vol.79
, pp. 143-180
-
-
Widmann, C.1
Gibson, S.2
Jarpe, M.B.3
Johnson, G.L.4
-
21
-
-
0033951487
-
The role of MAP kinases in intracellular signal transduction in bronchial epithelium
-
COI: 1:CAS:528:DC%2BD3cXhtlGms7s%3D, PID: 10606925
-
Puddicombe SM, Davies DE. The role of MAP kinases in intracellular signal transduction in bronchial epithelium. Clin Exp Allergy. 2000;30:7–11.
-
(2000)
Clin Exp Allergy
, vol.30
, pp. 7-11
-
-
Puddicombe, S.M.1
Davies, D.E.2
-
22
-
-
0033800083
-
Extracellular signals and scores of phosphatases: all roads lead to MAP kinase
-
COI: 1:CAS:528:DC%2BD3cXmsFKlsbY%3D, PID: 10995585
-
Saxena M, Mustelin T. Extracellular signals and scores of phosphatases: all roads lead to MAP kinase. Semin Immunol. 2000;12:387–96.
-
(2000)
Semin Immunol
, vol.12
, pp. 387-396
-
-
Saxena, M.1
Mustelin, T.2
-
23
-
-
84907691718
-
CCR7 regulates cell migration and invasion through MAPKs in metastatic squamous cell carcinoma of head and neck
-
Liu FY, Safdar J, Li ZN, Fang QG, Zhang X, Xu ZF, et al. CCR7 regulates cell migration and invasion through MAPKs in metastatic squamous cell carcinoma of head and neck. Int J Oncol. 2014. doi:10.3892/ijo.2014.2674.
-
Int J Oncol. 2014. doi:10.3892/ijo
, vol.2014
, pp. 2674
-
-
Liu, F.Y.1
Safdar, J.2
Li, Z.N.3
Fang, Q.G.4
Zhang, X.5
Xu, Z.F.6
-
24
-
-
84906934728
-
Matrix metalloproteinase-9 is up-regulated by CCL19/CCR7 interaction via PI3K/Akt pathway and is involved in CCL19-driven BMSCs migration
-
COI: 1:CAS:528:DC%2BC2cXht12nt7%2FJ, PID: 25086360
-
Zhang W, Tu G, Lv C, Long J, Cong L, Han Y. Matrix metalloproteinase-9 is up-regulated by CCL19/CCR7 interaction via PI3K/Akt pathway and is involved in CCL19-driven BMSCs migration. Biochem Biophys Res Commun. 2014;451:222–8.
-
(2014)
Biochem Biophys Res Commun
, vol.451
, pp. 222-228
-
-
Zhang, W.1
Tu, G.2
Lv, C.3
Long, J.4
Cong, L.5
Han, Y.6
-
25
-
-
0141760411
-
Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells
-
Imai T, Horiuchi A, Wang C, Oka K, Ohira S, Nikaido T, et al. Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells. Am J Pathol. 2003;3:1437–47.
-
(2003)
Am J Pathol
, vol.3
, pp. 1437-1447
-
-
Imai, T.1
Horiuchi, A.2
Wang, C.3
Oka, K.4
Ohira, S.5
Nikaido, T.6
-
26
-
-
84879466738
-
Stabilization of Snail through AKT/GASK-3β signaling pathway is required for TNF-a-induced epithelial-mesenchymal transition in prostate cancer PC3 cells
-
COI: 1:CAS:528:DC%2BC3sXhtlCgtbfK, PID: 23769744
-
Wang H, Fang R, Wang XF, Zhang F, Chen DY, Zhou B, et al. Stabilization of Snail through AKT/GASK-3β signaling pathway is required for TNF-a-induced epithelial-mesenchymal transition in prostate cancer PC3 cells. Eur J Pharmacol. 2013;714:48–55.
-
(2013)
Eur J Pharmacol
, vol.714
, pp. 48-55
-
-
Wang, H.1
Fang, R.2
Wang, X.F.3
Zhang, F.4
Chen, D.Y.5
Zhou, B.6
-
27
-
-
84857236729
-
ERK/GSK3β/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition
-
COI: 1:CAS:528:DC%2BC38XjtFSgt7k%3D, PID: 22198183
-
Nagarajan D, Melo T, Deng Z, Almeida C, Zhao W. ERK/GSK3β/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition. Free Radic Biol Med. 2012;52:983–92.
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 983-992
-
-
Nagarajan, D.1
Melo, T.2
Deng, Z.3
Almeida, C.4
Zhao, W.5
-
28
-
-
62549163846
-
Hypoxia induced CCR7 expression via HIF-1alpha and HIF-2alpha correlates with migration and invasion in lung cancer cells
-
COI: 1:CAS:528:DC%2BD1MXotV2qtLw%3D, PID: 19305150
-
Li Y, Qiu X, Zhang S, Zhang Q, Wang E. Hypoxia induced CCR7 expression via HIF-1alpha and HIF-2alpha correlates with migration and invasion in lung cancer cells. Cancer Biol Ther. 2009;8:322–30.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 322-330
-
-
Li, Y.1
Qiu, X.2
Zhang, S.3
Zhang, Q.4
Wang, E.5
-
29
-
-
36849021771
-
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
-
Higgins DF, Kimura K, Bernhardt WM, Shrimanker N, Akai Y, Hohenstein B, et al. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest. 2007;3:3810–20.
-
(2007)
J Clin Invest
, vol.3
, pp. 3810-3820
-
-
Higgins, D.F.1
Kimura, K.2
Bernhardt, W.M.3
Shrimanker, N.4
Akai, Y.5
Hohenstein, B.6
-
30
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
Sahlgren C, Gustafsson MV, Jin S, Poellinger L, Lendahl U. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci U S A. 2008;3:6392–7.
-
(2008)
Proc Natl Acad Sci U S A
, vol.3
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
Poellinger, L.4
Lendahl, U.5
-
31
-
-
33947217823
-
Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia
-
Kaidi A, Williams AC, Paraskeva C. Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia. Nat Cell Biol. 2007;3:210–7.
-
(2007)
Nat Cell Biol
, vol.3
, pp. 210-217
-
-
Kaidi, A.1
Williams, A.C.2
Paraskeva, C.3
-
32
-
-
84855340668
-
SET8 promotes epithelial–mesenchymal transition and confers TWIST dual transcriptional activities
-
Yang F, Sun L, Li Q, Han X, Lei L, Zhang H, et al. SET8 promotes epithelial–mesenchymal transition and confers TWIST dual transcriptional activities. EMBO J. 2012;3:110–23.
-
(2012)
EMBO J
, vol.3
, pp. 110-123
-
-
Yang, F.1
Sun, L.2
Li, Q.3
Han, X.4
Lei, L.5
Zhang, H.6
|