-
1
-
-
0031685620
-
TGF-β signal transduction
-
9759503 10.1146/annurev.biochem.67.1.753
-
Massagué J (1998) TGF-β signal transduction. Annu Rev Biochem 67:753-91
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 753-791
-
-
Massagué, J.1
-
2
-
-
0242413065
-
Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development
-
14623443 10.1016/j.mod.2003.06.005 1:CAS:528:DC%2BD3sXptVWnsrY%3D
-
Shook D, Keller R (2003) Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development. Mech Dev 120:1351-83
-
(2003)
Mech Dev
, vol.120
, pp. 1351-1383
-
-
Shook, D.1
Keller, R.2
-
3
-
-
0036233040
-
Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation
-
11967021 10.1046/j.1523-1755.2002.00333.x 1:CAS:528:DC%2BD38XjvFWhsr0%3D
-
Strutz F, Zeisberg M, Ziyadeh FN, Yang CQ, Kalluri R, Müller GA, Neilson EG (2002) Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney Int 61:1714-28
-
(2002)
Kidney Int
, vol.61
, pp. 1714-1728
-
-
Strutz, F.1
Zeisberg, M.2
Ziyadeh, F.N.3
Yang, C.Q.4
Kalluri, R.5
Müller, G.A.6
Neilson, E.G.7
-
4
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
19487818 10.1172/JCI39104 1:CAS:528:DC%2BD1MXntVCjtr0%3D
-
Kalluri R, Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420-28
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
5
-
-
0028170226
-
Mechanism of activation of TGF-β receptor
-
8047140 10.1038/370341a0 1:CAS:528:DyaK2cXlt1Kju78%3D
-
Wrana JL, Attisano L, Wieser R, Ventura F, Massagué J (1994) Mechanism of activation of TGF-β receptor. Nature 370:341-47
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
Attisano, L.2
Wieser, R.3
Ventura, F.4
Massagué, J.5
-
6
-
-
0038682002
-
Mechanisms of TGF-β signaling from cell membrane to the nucleus
-
12809600 10.1016/S0092-8674(03)00432-X 1:CAS:528:DC%2BD3sXkvVekt7o%3D
-
Shi Y, Massagué J (2003) Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 113:685-700
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massagué, J.2
-
8
-
-
0035970096
-
Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase
-
11158580 10.1073/pnas.98.3.974 1:CAS:528:DC%2BD3MXht1Sms7s%3D
-
Zhang Y, Chang C, Gehling JD, Hemmati-Brivanlou A, Derynck R (2001) Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. Proc Natl Acad Sci U S A 98:974-79
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 974-979
-
-
Zhang, Y.1
Chang, C.2
Gehling, J.D.3
Hemmati-Brivanlou, A.4
Derynck, R.5
-
9
-
-
0032428684
-
SARA, a FYVE domain protein that recruits Smad2 to the TGF-β receptor
-
9865696 10.1016/S0092-8674(00)81701-8 1:CAS:528:DyaK1MXivVKj
-
Tsukazaki T, Chiang TA, Davison AF, Attisano L, Wrana L (1998) SARA, a FYVE domain protein that recruits Smad2 to the TGF-β receptor. Cell 95:779-91
-
(1998)
Cell
, vol.95
, pp. 779-791
-
-
Tsukazaki, T.1
Chiang, T.A.2
Davison, A.F.3
Attisano, L.4
Wrana, L.5
-
10
-
-
0037598870
-
Distinct endocytic pathways regulate TGF-β receptor signalling and turnover
-
12717440 10.1038/ncb975
-
Di Guglielmo GM, Le Roy C, Goodfellow AF, Wrana L (2003) Distinct endocytic pathways regulate TGF-β receptor signalling and turnover. Nat Cell Biol 5:410-21
-
(2003)
Nat Cell Biol
, vol.5
, pp. 410-421
-
-
Di Guglielmo, G.M.1
Le Roy, C.2
Goodfellow, A.F.3
Wrana, L.4
-
11
-
-
58149269185
-
Endocytic regulation of TGF-β signaling
-
19050695 10.1038/cr.2008.315
-
Chen YG (2009) Endocytic regulation of TGF-β signaling. Cell Res 19:58-70
-
(2009)
Cell Res
, vol.19
, pp. 58-70
-
-
Chen, Y.G.1
-
12
-
-
34248149074
-
Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling
-
17272273 10.1074/jbc.M611704200 1:CAS:528:DC%2BD2sXjtlCitbs%3D
-
Chen YG, Wang Z, Ma Y, Zhang L, Lu Z (2007) Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling. J Biol Chem 282:9688-96
-
(2007)
J Biol Chem
, vol.282
, pp. 9688-9696
-
-
Chen, Y.G.1
Wang, Z.2
Ma, Y.3
Zhang, L.4
Lu, Z.5
-
13
-
-
0035871081
-
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
-
11284710 10.1042/0264-6021:3550249 1:CAS:528:DC%2BD3MXjsValtbg%3D
-
Gillooly DJ, Simonsen A, Stenmark H (2001) Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins. Biochem J 355:249-58
-
(2001)
Biochem J
, vol.355
, pp. 249-258
-
-
Gillooly, D.J.1
Simonsen, A.2
Stenmark, H.3
-
14
-
-
0036201871
-
The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling
-
11918675 10.1046/j.1365-2443.2002.00519.x 1:CAS:528:DC%2BD38XjtVOguro%3D
-
Itoh F, Divecha N, Brocks L, Brocks L, Oomen L, Janssen H, Calafar J, Itoh S, Dijke PP (2002) The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling. Genes Cells 7:321-31
-
(2002)
Genes Cells
, vol.7
, pp. 321-331
-
-
Itoh, F.1
Divecha, N.2
Brocks, L.3
Brocks, L.4
Oomen, L.5
Janssen, H.6
Calafar, J.7
Itoh, S.8
Dijke, P.P.9
-
15
-
-
13444263549
-
Clathrin- and non-clathrin- mediated endocytic regulation of cell signalling
-
10.1038/nrm1571
-
Le Roy C, Wrana L (2005) Clathrin- and non-clathrin- mediated endocytic regulation of cell signalling. Nat Rev Cell Biol 6:112-26
-
(2005)
Nat Rev Cell Biol
, vol.6
, pp. 112-126
-
-
Le Roy, C.1
Wrana, L.2
-
16
-
-
0038557042
-
Coat proteins: Shaping membrane transport
-
12728274 10.1038/nrm1099 1:CAS:528:DC%2BD3sXjtlalt74%3D
-
Bonifacino JS, Lippincott-Schwartz J (2003) Coat proteins: shaping membrane transport. Nat Rev Mol Cell Biol 4:409-14
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 409-414
-
-
Bonifacino, J.S.1
Lippincott-Schwartz, J.2
-
17
-
-
0038795645
-
Signals for sorting of transmembrane proteins to endosomes and lysosomes
-
12651740 10.1146/annurev.biochem.72.121801.161800 1:CAS:528: DC%2BD3sXntFSgtLc%3D
-
Bonifacino JS, Traub LM (2003) Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu Rev Biochem 72:395-447
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 395-447
-
-
Bonifacino, J.S.1
Traub, L.M.2
-
18
-
-
0037144841
-
TGFβ receptor internalization into EEA1-enriched early endosomes: Role in signaling to Smad2
-
12356868 10.1083/jcb.200204088 1:CAS:528:DC%2BD38Xns1equr4%3D
-
Hayes S, Chawla A, Corvera S (2002) TGFβ receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2. J Cell Biol 158:1239-49
-
(2002)
J Cell Biol
, vol.158
, pp. 1239-1249
-
-
Hayes, S.1
Chawla, A.2
Corvera, S.3
-
19
-
-
0036272313
-
Internalization-dependent and -independent requirements for trasfotming growth factor beta receptor signaling via the Smad pathway
-
12052882 10.1128/MCB.22.13.4750-4759.2002 1:CAS:528:DC%2BD38Xks1yrtr0%3D
-
Penheiter SG, Mitchell H, Garamszegi N, Edens M, Dore JJJ, Leof EB (2002) Internalization-dependent and -independent requirements for trasfotming growth factor beta receptor signaling via the Smad pathway. Mol Cell Biol 22:4750-59
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4750-4759
-
-
Penheiter, S.G.1
Mitchell, H.2
Garamszegi, N.3
Edens, M.4
Dore, J.J.J.5
Leof, E.B.6
-
20
-
-
0034253480
-
The nuclear import function of Smad2 is masked by SARA and unmasked by TGFb-dependent phosphorylation
-
10934479 10.1038/35010529 1:CAS:528:DC%2BD3cXlslymtL0%3D
-
Xu L, Chen YG, Massagué J (2000) The nuclear import function of Smad2 is masked by SARA and unmasked by TGFb-dependent phosphorylation. Nat Cell Biol 2:559-62
-
(2000)
Nat Cell Biol
, vol.2
, pp. 559-562
-
-
Xu, L.1
Chen, Y.G.2
Massagué, J.3
-
21
-
-
84859437880
-
Role of Smads in TGFβ signaling
-
21643690 10.1007/s00441-011-1190-x 1:CAS:528:DC%2BC38Xkslertw%3D%3D
-
Heldin CH, Moustakas A (2012) Role of Smads in TGFβ signaling. Cell Tissue Res 347:21-36
-
(2012)
Cell Tissue Res
, vol.347
, pp. 21-36
-
-
Heldin, C.H.1
Moustakas, A.2
-
22
-
-
0035167095
-
Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner
-
11294908 1:CAS:528:DC%2BD3MXjtVaqsbc%3D
-
Kurisaki A, Kose S, Yoneda Y, Heldin CH, Moustakas A (2001) Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner. Mol Biol Cell 12:1079-91
-
(2001)
Mol Biol Cell
, vol.12
, pp. 1079-1091
-
-
Kurisaki, A.1
Kose, S.2
Yoneda, Y.3
Heldin, C.H.4
Moustakas, A.5
-
23
-
-
0037455715
-
An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity
-
12592392 10.1038/sj.onc.1206212 1:CAS:528:DC%2BD3sXht1Gkt74%3D
-
Xiao Z, Latek R, Lodish HF (2003) An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity. Oncogene 22:1057-69
-
(2003)
Oncogene
, vol.22
, pp. 1057-1069
-
-
Xiao, Z.1
Latek, R.2
Lodish, H.F.3
-
24
-
-
4344606636
-
Ligand-dependent and -independent transforming growth factor-beta receptor recycling regulated by clathrin-mediated endocytosis and Rab11
-
15229286 10.1091/mbc.E04-03-0245 1:CAS:528:DC%2BD2cXnt1eksbg%3D
-
Mitchell H, Choudhury A, Pagano RE, Leof EB (2004) Ligand-dependent and -independent transforming growth factor-beta receptor recycling regulated by clathrin-mediated endocytosis and Rab11. Mol Biol Cell 15:4166-78
-
(2004)
Mol Biol Cell
, vol.15
, pp. 4166-4178
-
-
Mitchell, H.1
Choudhury, A.2
Pagano, R.E.3
Leof, E.B.4
-
25
-
-
0028285191
-
Caveolae, caveolin and caveolin-rich membrane domains: A signalling hypothesis
-
14731661 10.1016/0962-8924(94)90114-7 1:CAS:528:DyaK2MXjsVyrtQ%3D%3D
-
Lisanti MP, Scherer P, Tang ZL, Sargiacomo M (1994) Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis. Trends Cell Biol 4:231-35
-
(1994)
Trends Cell Biol
, vol.4
, pp. 231-235
-
-
Lisanti, M.P.1
Scherer, P.2
Tang, Z.L.3
Sargiacomo, M.4
-
26
-
-
0342506499
-
Molecular and cellular biology of caveolae: Paradoxes and plasticities
-
21235872 10.1016/S1050-1738(97)00001-7 1:CAS:528:DyaK2sXktVCls70%3D
-
Couet J, Li S, Okamoto T, Scherer P, Lisanti MP (1997) Molecular and cellular biology of caveolae: paradoxes and plasticities. Trends Cardiovasc Med 7:103-10
-
(1997)
Trends Cardiovasc Med
, vol.7
, pp. 103-110
-
-
Couet, J.1
Li, S.2
Okamoto, T.3
Scherer, P.4
Lisanti, M.P.5
-
27
-
-
0035017308
-
Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular transport pathway to the ER
-
10.1038/35074539
-
Pelkmans L, Kartenbeck J, Helenius A (2001) Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular transport pathway to the ER. Nat Cell Biol 3:475-83
-
(2001)
Nat Cell Biol
, vol.3
, pp. 475-483
-
-
Pelkmans, L.1
Kartenbeck, J.2
Helenius, A.3
-
28
-
-
0036094927
-
A distinct class of endosome mediates clathrin- independent endocytosis to the Golgi complex
-
Nicols BJ (2002) A distinct class of endosome mediates clathrin- independent endocytosis to the Golgi complex. Nat Cell Biol 4:374-78
-
(2002)
Nat Cell Biol
, vol.4
, pp. 374-378
-
-
Nicols, B.J.1
-
29
-
-
33847181297
-
The multiple faces of caveolae
-
17318224 10.1038/nrm2122 1:CAS:528:DC%2BD2sXitVGrsrk%3D
-
Parton RG, Simons K (2007) The multiple faces of caveolae. Nat Rev Mol Cell Biol 8:185-94
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 185-194
-
-
Parton, R.G.1
Simons, K.2
-
30
-
-
68149167385
-
Endocytosis via caveolae: Alternative pathway with distinct cellular compartments to avoid lysosomal degradation?
-
19382909 10.1111/j.1582-4934.2009.00754.x
-
Kiss AL, Botos E (2009) Endocytosis via caveolae: alternative pathway with distinct cellular compartments to avoid lysosomal degradation? J Cell Mol Med 13:1228-37
-
(2009)
J Cell Mol Med
, vol.13
, pp. 1228-1237
-
-
Kiss, A.L.1
Botos, E.2
-
31
-
-
78049508213
-
Caveolin-1 is ubiquitinated and targeted to intraluminal vesicles in endolysosomes for degradation
-
21041450 10.1083/jcb.201003086 1:CAS:528:DC%2BC3cXhsVamsr%2FK
-
Hayer A, Stoaber M, Ritz D, Engel S, Meyer HH, Helenius A (2010) Caveolin-1 is ubiquitinated and targeted to intraluminal vesicles in endolysosomes for degradation. J Cell Biol 191:615-29
-
(2010)
J Cell Biol
, vol.191
, pp. 615-629
-
-
Hayer, A.1
Stoaber, M.2
Ritz, D.3
Engel, S.4
Meyer, H.H.5
Helenius, A.6
-
32
-
-
0030611757
-
Identification of Smad7, a TGF-beta inducible antagonist of TGF-beta signalling
-
9335507 10.1038/39369 1:CAS:528:DyaK2sXmslWksrs%3D
-
Nakao A, Afrakhte M, Moren A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, PtP D (1997) Identification of Smad7, a TGF-beta inducible antagonist of TGF-beta signalling. Nature 389:631-35
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
Itoh, S.7
Kawabata, M.8
Heldin, N.E.9
Heldin, C.H.10
Ptp, D.11
-
33
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
-
9215638 10.1016/S0092-8674(00)80303-7 1:CAS:528:DyaK2sXkt1Kks70%3D
-
Hayashi H, Abdollah S, Qui Y, Cai J, Xu JJ, Grinnell BW, Richardson MA, Topper JN, Gimbrone MA Jr, Wrana JL, Falb D (1997) The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell 89:1165-73
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qui, Y.3
Cai, J.4
Xu, J.J.5
Grinnell, B.W.6
Richardson, M.A.7
Topper, J.N.8
Gimbrone, Jr.M.A.9
Wrana, J.L.10
Falb, D.11
-
34
-
-
34250203586
-
Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation
-
17438144 10.1128/MCB.01636-06 1:CAS:528:DC%2BD2sXmvFansb0%3D
-
Zhang S, Fei T, Zhang L, Zhang R, Chen F, Ning Y, Han Y, Feng XH, Meng A, Chen YG (2007) Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation. Mol Cell Biol 27:4488-99
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4488-4499
-
-
Zhang, S.1
Fei, T.2
Zhang, L.3
Zhang, R.4
Chen, F.5
Ning, Y.6
Han, Y.7
Feng, X.H.8
Meng, A.9
Chen, Y.G.10
-
35
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-beta receptor for degradation
-
11163210 10.1016/S1097-2765(00)00134-9 1:CAS:528:DC%2BD3MXlvFahug%3D%3D
-
Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL (2000) Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-beta receptor for degradation. Mol Cell 6:1365-75
-
(2000)
Mol Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
Wrana, J.L.7
-
36
-
-
0035918274
-
Smurf1 interacts with transforming growth factor-beta type-I receptor through Smad7 and induces receptor degradation
-
11278251 10.1074/jbc.C100008200 1:CAS:528:DC%2BD3MXjtFynsbk%3D
-
Ebisawa T, Fukuchi M, Murakami G, Chiba T, Tanaka K, Imamura T, Miyazono K (2001) Smurf1 interacts with transforming growth factor-beta type-I receptor through Smad7 and induces receptor degradation. J Biol Chem 276:12477-80
-
(2001)
J Biol Chem
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
Fukuchi, M.2
Murakami, G.3
Chiba, T.4
Tanaka, K.5
Imamura, T.6
Miyazono, K.7
-
37
-
-
0032582672
-
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7
-
9786930 10.1074/jbc.273.44.29195 1:CAS:528:DyaK1cXntlaksL4%3D
-
Itoh S, Landström M, Hermansson A, Itoh F, Heldin CH, Heldin NE, PtP D (1998) Transforming growth factor beta1 induces nuclear export of inhibitory Smad7. J Biol Chem 273:29195-201
-
(1998)
J Biol Chem
, vol.273
, pp. 29195-29201
-
-
Itoh, S.1
Landström, M.2
Hermansson, A.3
Itoh, F.4
Heldin, C.H.5
Heldin, N.E.6
Ptp, D.7
-
38
-
-
50249140644
-
TGFbeta induces SIK to negatively regulate type i receptor kinase signaling
-
18725536 10.1083/jcb.200804107 1:CAS:528:DC%2BD1cXhtV2rurzP
-
Kowanetz M, Lönn P, Vanlandewijck M, Kowanetz K, Heldin CH, Moustakas A (2008) TGFbeta induces SIK to negatively regulate type I receptor kinase signaling. J Cell Biol 182:655-62
-
(2008)
J Cell Biol
, vol.182
, pp. 655-662
-
-
Kowanetz, M.1
Lönn, P.2
Vanlandewijck, M.3
Kowanetz, K.4
Heldin, C.H.5
Moustakas, A.6
-
39
-
-
79955667316
-
The TFG-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors
-
21295082 10.1016/j.bbamcr.2011.01.028 1:CAS:528:DC%2BC3MXkvFagsLo%3D
-
Bizet AA, Liu K, Tran-Khanh N, Saksena A, Vorstenbosch J, Finnson KW, Buschmann MD, Philip A (2011) The TFG-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors. Biochim Biophys Acta 1813:742-53
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 742-753
-
-
Bizet, A.A.1
Liu, K.2
Tran-Khanh, N.3
Saksena, A.4
Vorstenbosch, J.5
Finnson, K.W.6
Buschmann, M.D.7
Philip, A.8
-
40
-
-
33846471122
-
Proteasome-independent functions of ubiquitin in endocytosis and signaling
-
17218518 10.1126/science.1127085 1:CAS:528:DC%2BD2sXivFOisw%3D%3D
-
Mukhopadhyay D, Riezman H (2007) Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science 315:201-205
-
(2007)
Science
, vol.315
, pp. 201-205
-
-
Mukhopadhyay, D.1
Riezman, H.2
-
41
-
-
11244309014
-
Proteolysis: From the lysosome to ubiquitin and the proteasome
-
1:CAS:528:DC%2BD2MXlvVWr
-
Ciechanover A (2005) Proteolysis: from the lysosome to ubiquitin and the proteasome. Mol Cel Biol 6:79-86
-
(2005)
Mol Cel Biol
, vol.6
, pp. 79-86
-
-
Ciechanover, A.1
-
42
-
-
0025359062
-
Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body
-
2344614 10.1016/0092-8674(90)90474-S 1:CAS:528:DyaK3cXktlGgt7g%3D
-
Felder S, Miller K, Moshren G, Ullrich A, Schlessinger J, Hopkins CR (1990) Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body. Cell 61:623-34
-
(1990)
Cell
, vol.61
, pp. 623-634
-
-
Felder, S.1
Miller, K.2
Moshren, G.3
Ullrich, A.4
Schlessinger, J.5
Hopkins, C.R.6
-
43
-
-
0029100974
-
Membrane transport in the endocytic pathway
-
7495576 10.1016/0955-0674(95)80013-1 1:STN:280:DyaK28%2Fgt1yrtw%3D%3D
-
Gruenberg J, Maxfield F (1995) Membrane transport in the endocytic pathway. Curr Op Cell Biol 7:552-63
-
(1995)
Curr Op Cell Biol
, vol.7
, pp. 552-563
-
-
Gruenberg, J.1
Maxfield, F.2
-
44
-
-
0034646674
-
Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta
-
10.1074/jbc.275.15.11320
-
von Gersdoff G, Susztak K, Rezvani F, Bitzer M, Liang D, Böttinger EP (2000) Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta. J Biol Chem 275:11320-26
-
(2000)
J Biol Chem
, vol.275
, pp. 11320-11326
-
-
Von Gersdoff, G.1
Susztak, K.2
Rezvani, F.3
Bitzer, M.4
Liang, D.5
Böttinger, E.P.6
-
45
-
-
0035958546
-
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I
-
11511343 10.1016/S0092-8674(01)00434-2 1:CAS:528:DC%2BD3MXlvVClsL8%3D
-
Katzmann DJ, Babst M, Emr DS (2001) Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106:145-55
-
(2001)
Cell
, vol.106
, pp. 145-155
-
-
Katzmann, D.J.1
Babst, M.2
Emr, D.S.3
-
46
-
-
80052860533
-
How ubiqitination regulates the TGF-β signalling pathway: New insights and new players
-
21932223 10.1002/bies.201100057 1:CAS:528:DC%2BC3MXhtFGqu7bP
-
Soond SM, Chantry A (2011) How ubiqitination regulates the TGF-β signalling pathway: new insights and new players. Bioessays 33:749-58
-
(2011)
Bioessays
, vol.33
, pp. 749-758
-
-
Soond, S.M.1
Chantry, A.2
-
47
-
-
77951992339
-
Estrogen inhibits transforming growth factor β signaling by promoting Smad2/3 degradation
-
20207742 10.1074/jbc.M109.093039 1:CAS:528:DC%2BC3cXlsVOhsbk%3D
-
Ito I, Hanyu A, Wayama M, Goto N, Katsuno Y, Kawasaki S, Nakajima Y, Kajiro M, Komatsu Y, Fujimura A, Hirota R, Murayama A, Kimura K, Imamura T, Yanagisawa J (2010) Estrogen inhibits transforming growth factor β signaling by promoting Smad2/3 degradation. J Biol Chem 285:14747-55
-
(2010)
J Biol Chem
, vol.285
, pp. 14747-14755
-
-
Ito, I.1
Hanyu, A.2
Wayama, M.3
Goto, N.4
Katsuno, Y.5
Kawasaki, S.6
Nakajima, Y.7
Kajiro, M.8
Komatsu, Y.9
Fujimura, A.10
Hirota, R.11
Murayama, A.12
Kimura, K.13
Imamura, T.14
Yanagisawa, J.15
-
48
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-β family signalling
-
10.1038/nature02006
-
Derynck R, Zhang YE (2003) Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 424:577-584
-
(2003)
Nature
, vol.424
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
49
-
-
24944497786
-
Non-Smad TGF-β signals
-
16105881 10.1242/jcs.02554 1:CAS:528:DC%2BD2MXhtVaktrvK
-
Moustakas A, Heldin CH (2005) Non-Smad TGF-β signals. J Cell Sci 118:3573-3584
-
(2005)
J Cell Sci
, vol.118
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.H.2
-
50
-
-
21644449056
-
Protein-protein interactions in the regulation of the extracellular signal-regulated kinase
-
10.1385/MB:29:1:57 1:CAS:528:DC%2BD2MXmtl2rurk%3D
-
Chuderland D, Seger R (2005) Protein-protein interactions in the regulation of the extracellular signal-regulated kinase. Mol Biothechnol 29:57-74
-
(2005)
Mol Biothechnol
, vol.29
, pp. 57-74
-
-
Chuderland, D.1
Seger, R.2
-
51
-
-
0034610996
-
Nuclear export of MAP kinase (Erk) involves a MAP kinase kinase (MEK)-dependent active transport mechanism
-
10704436 10.1083/jcb.148.5.849 1:CAS:528:DC%2BD3cXhslansrw%3D
-
Adachi M, Fukuda M, Nishida E (2000) Nuclear export of MAP kinase (Erk) involves a MAP kinase kinase (MEK)-dependent active transport mechanism. J Cell Biol 148:849-856
-
(2000)
J Cell Biol
, vol.148
, pp. 849-856
-
-
Adachi, M.1
Fukuda, M.2
Nishida, E.3
-
52
-
-
0026608787
-
Nuclear localization and regulation of erk- and rsk-encoded protein kinase
-
1545823 1:CAS:528:DyaK38XhsV2jtbw%3D
-
Chen RH, Sarnecki C, Blenis J (1992) Nuclear localization and regulation of erk- and rsk-encoded protein kinase. Mol Cell Biol 12:915-927
-
(1992)
Mol Cell Biol
, vol.12
, pp. 915-927
-
-
Chen, R.H.1
Sarnecki, C.2
Blenis, J.3
-
53
-
-
12544257249
-
Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-β-mediated Smad-dependent growth inhibition of human breast carcinom cells in vivo
-
15520018 10.1074/jbc.M403960200 1:CAS:528:DC%2BD2MXitFChsQ%3D%3D
-
Kamaraju AK, Roberts AB (2005) Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-β-mediated Smad-dependent growth inhibition of human breast carcinom cells in vivo. J Biol Chem 280:1024-1036
-
(2005)
J Biol Chem
, vol.280
, pp. 1024-1036
-
-
Kamaraju, A.K.1
Roberts, A.B.2
-
54
-
-
6044261233
-
TGF-β and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker region
-
15326485 10.1038/sj.onc.1207981 1:CAS:528:DC%2BD2cXnsleltLo%3D
-
Mori S, Matsuzaki K, Yoshida K, Furukawa F, Tahashi Y, Yamagata H, Sekimoto G, Seki T, Matsui H, Nishizawa M, Fujisawa J, Okazaki K (2004) TGF-β and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker region. Oncogene 23:7416-7429
-
(2004)
Oncogene
, vol.23
, pp. 7416-7429
-
-
Mori, S.1
Matsuzaki, K.2
Yoshida, K.3
Furukawa, F.4
Tahashi, Y.5
Yamagata, H.6
Sekimoto, G.7
Seki, T.8
Matsui, H.9
Nishizawa, M.10
Fujisawa, J.11
Okazaki, K.12
-
55
-
-
0033106484
-
A mechanism of repression of TGF-β/Smad signaling by oncogenic Ras
-
10197981 10.1101/gad.13.7.804 1:CAS:528:DyaK1MXisF2isrg%3D
-
Kretzschmar M, Doody J, Timokhina I, Massagué J (1999) A mechanism of repression of TGF-β/Smad signaling by oncogenic Ras. Genes Dev 13:804-816
-
(1999)
Genes Dev
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massagué, J.4
-
56
-
-
0033601179
-
Interdependent Smad and JNK signaling in trasforming growth factor-β-mediated transcription
-
10601313 10.1074/jbc.274.52.37413 1:CAS:528:DC%2BD3cXpsFCg
-
Engel M, McDonnell MA, Law BK, Moses HL (1999) Interdependent Smad and JNK signaling in trasforming growth factor-β-mediated transcription. J Biol Chem 274:37413-37420
-
(1999)
J Biol Chem
, vol.274
, pp. 37413-37420
-
-
Engel, M.1
McDonnell, M.A.2
Law, B.K.3
Moses, H.L.4
-
57
-
-
68549123472
-
New regulatory mechanisms of TGF-β receptor function
-
19648010 10.1016/j.tcb.2009.05.008 1:CAS:528:DC%2BD1MXhtVSitLjF
-
Kang JS, Liu C, Derynck R (2009) New regulatory mechanisms of TGF-β receptor function. Trends Cell Biol 19:385-394
-
(2009)
Trends Cell Biol
, vol.19
, pp. 385-394
-
-
Kang, J.S.1
Liu, C.2
Derynck, R.3
-
58
-
-
34248584887
-
Src phosphorylates Tyr284 in TGF-β type II receptor and regulates TGF-β stimulation of p38 MAPK during brest cancer cell proliferation and invasion
-
17440088 10.1158/0008-5472.CAN-06-3851 1:CAS:528:DC%2BD2sXkt1Kitro%3D
-
Galliher AJ, Schiemann WP (2007) Src phosphorylates Tyr284 in TGF-β type II receptor and regulates TGF-β stimulation of p38 MAPK during brest cancer cell proliferation and invasion. Cancer Res 67:3752-3758
-
(2007)
Cancer Res
, vol.67
, pp. 3752-3758
-
-
Galliher, A.J.1
Schiemann, W.P.2
-
59
-
-
37049019067
-
Late endosomal traffic of epidermal growth factor receptor ensures spatial and temporal fidelity of mitogen-activated protein kinase signaling
-
17881733 10.1091/mbc.E07-02-0098 1:CAS:528:DC%2BD2sXhsVeisrfN
-
Taub N, Teis D, Ebner HL, Hess MW, Huber LA (2007) Late endosomal traffic of epidermal growth factor receptor ensures spatial and temporal fidelity of mitogen-activated protein kinase signaling. Mol Biol Cell 18:4698-4710
-
(2007)
Mol Biol Cell
, vol.18
, pp. 4698-4710
-
-
Taub, N.1
Teis, D.2
Ebner, H.L.3
Hess, M.W.4
Huber, L.A.5
-
60
-
-
71849119627
-
The subcellular localization of MEK and ERK-A novel nuclear translocation signal (NTS) paves a way to nucleus
-
10.1016/j.mce.2009.04.008 1:CAS:528:DC%2BD1MXhsFynurnE
-
Zehorai E, Yao Z, Plotnikov A, Seger R (2010) The subcellular localization of MEK and ERK-A novel nuclear translocation signal (NTS) paves a way to nucleus. Mol Cell End 314:213-220
-
(2010)
Mol Cell End
, vol.314
, pp. 213-220
-
-
Zehorai, E.1
Yao, Z.2
Plotnikov, A.3
Seger, R.4
-
61
-
-
64049102327
-
Specific activation of mitogen-activated protein kinase by transforming growth factor-β receptors in lipid rafts is required for epithelial cell plasticity
-
19056678 10.1091/mbc.E08-09-0898 1:CAS:528:DC%2BD1MXisVSnt7w%3D
-
Zuo W, Chen YG (2009) Specific activation of mitogen-activated protein kinase by transforming growth factor-β receptors in lipid rafts is required for epithelial cell plasticity. Mol Biol Cell 20:1020-1029
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1020-1029
-
-
Zuo, W.1
Chen, Y.G.2
-
62
-
-
47249112135
-
Isoform-specific interaction of C-RAF with mitochondria
-
18356164 10.1074/jbc.M709098200 1:CAS:528:DC%2BD1cXlvFyjt7Y%3D
-
Galmiche A, Fueller J, Santel A, Krohne G, Witting I, Doye A, Rolando M, Flatau G, Lemichez E, Rapp UR (2008) Isoform-specific interaction of C-RAF with mitochondria. J Biol Chem 283:14857-14866
-
(2008)
J Biol Chem
, vol.283
, pp. 14857-14866
-
-
Galmiche, A.1
Fueller, J.2
Santel, A.3
Krohne, G.4
Witting, I.5
Doye, A.6
Rolando, M.7
Flatau, G.8
Lemichez, E.9
Rapp, U.R.10
-
63
-
-
0033215340
-
Two co-existing mechanisms for nuclear import of MAP kinase: Passive diffusion of a monomer and active transport of a dimer
-
10508167 10.1093/emboj/18.19.5347 1:CAS:528:DyaK1MXntFKqsLw%3D
-
Adachi M, Fukuda M, Nishida E (1999) Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer. EMBO J 18:5347-5358
-
(1999)
EMBO J
, vol.18
, pp. 5347-5358
-
-
Adachi, M.1
Fukuda, M.2
Nishida, E.3
-
64
-
-
0029786994
-
Cytoplasmic localization of MAP kinase kinase directed by its N-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal
-
8702720 10.1074/jbc.271.33.20024 1:CAS:528:DyaK28XltVKrsbk%3D
-
Fukuda M, Gotoh I, Gotoh Y, Nishida E (1996) Cytoplasmic localization of MAP kinase kinase directed by its N-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal. J Biol Chem 271:20024-20028
-
(1996)
J Biol Chem
, vol.271
, pp. 20024-20028
-
-
Fukuda, M.1
Gotoh, I.2
Gotoh, Y.3
Nishida, E.4
-
65
-
-
0030972494
-
Interaction of MAP kinase with MAP kinase kinase: Its possible role in the control of nucleocytoplasmic transport of MAP kinase
-
9155016 10.1093/emboj/16.8.1901 1:CAS:528:DyaK2sXjt1WlsLc%3D
-
Fukuda M, Gotoh Y, Nishida E (1997) Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J 16:1901-1908
-
(1997)
EMBO J
, vol.16
, pp. 1901-1908
-
-
Fukuda, M.1
Gotoh, Y.2
Nishida, E.3
|