NADPH oxidase NOX1 is involved in activation of protein kinase C and premature senescence in early stage diabetic kidney

Free Radical Biology and Medicine

Volumn 83, Issue , 2015, Pages 21-30

  Zhu, Kai ^a   Kakehi, Tomoko ^a   Matsumoto, Misaki ^a   Iwata, Kazumi ^a   Ibi, Masakazu ^a   Ohshima, Yoichi ^a   Zhang, Jia ^a   Liu, Junjie ^a   Wen, Xiaopeng ^a   Taye, Ashraf ^a,d   Fan, Chunyuan ^c   Katsuyama, Masato ^a   Sharma, Kumar ^b   Yabe Nishimura, Chihiro ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c Faculty of Medical Sciences   (China)

^d Minia University   (Egypt)

Author keywords

Diabetic nephropathy; Free radicals; NADPH oxidase; NOX1; Protein kinase C; Senescence

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BETA GALACTOSIDASE; HISTONE H2A; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B BETA; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN P16; PROTEIN P21; PROTEIN P27; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; STREPTOZOCIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DNA STRAND BREAKAGE; ENZYME ACTIVATION; GLOMERULUS; HYPERGLYCEMIA; KIDNEY CORTEX; MEMBRANE TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENESCENCE; UPREGULATION; ANIMAL; C57BL MOUSE; CELL AGING; CELL CULTURE; CHEMICALLY INDUCED; ENZYME IMMUNOASSAY; EXPERIMENTAL DIABETES MELLITUS; GENETICS; KNOCKOUT MOUSE; MALE; MESANGIUM; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

MUS;

ANIMALS; BETA-GALACTOSIDASE; BLOTTING, WESTERN; CELL AGING; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; GLOMERULAR MESANGIUM; HYPERGLYCEMIA; IMMUNOENZYME TECHNIQUES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NADH, NADPH OXIDOREDUCTASES; OXIDATION-REDUCTION; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84925699870     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.02.009     Document Type: Article

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