Neuroprotective effect of 6-paradol in focal cerebral ischemia involves the attenuation of neuroinflammatory responses in activated microglia

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Gaire, Bhakta Prasad ^a   Kwon, Oh Wook ^a   Park, Sung Hyuk ^a   Chun, Kwang Hoon ^a   Kim, Sun Yeou ^a   Shin, Dong Yun ^a   Choi, Ji Woong ^a  

^a Gachon University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

10 PARADOL [1 (4 HYDROXY 3 METHOXYPHENYL)TETRADECAN 3 ONE]; 2 PARADOL [1 (4 HYDROXY 3 METHOXYPHENYL)HEXAN 3 ONE]; 4 PARADOL [1 (4 HYDROXY 3 METHOXYPHENYL)OCTAN 3 ONE]; 6 PARADOL [1 (4 HYDROXY 3 METHOXYPHENYL)DECAN 3 ONE]; 8 PARADOL [1 (4 HYDROXY 3 METHOXYPHENYL)DODECAN 3 ONE]; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITRIC OXIDE; SHOGAOL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 6-PARADOL; GUAIACOL; KETONE; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN DAMAGE; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL ACTIVATION; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL; NERVOUS SYSTEM INFLAMMATION; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; BRAIN; CELL LINE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PATHOLOGY; REPERFUSION INJURY; SYNTHESIS;

MUS;

ANIMALS; APOPTOSIS; BRAIN; BRAIN ISCHEMIA; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; GUAIACOL; INTERLEUKIN-6; KETONES; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED ICR; MICROGLIA; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; REPERFUSION INJURY; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84925637929     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120203     Document Type: Article

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