Methadone is a local anaesthetic-like inhibitor of neuronal Na+ channels and blocks excitability of mouse peripheral nerves

British Journal of Anaesthesia

Volumn 114, Issue 1, 2015, Pages 110-120

  Stoetzer, C ^a   Kistner, K ^b   Stuber T ^a   Wirths, M ^a   Schulze, V ^a   Doll, T ^a   Foadi, N ^a   Wegner, F ^a   Ahrens, J ^a   Leffler, A ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

bupivacaine; local anaesthetic; methadone; nerve block; sodium channel

Indexed keywords

BUPIVACAINE; LOCAL ANESTHETIC AGENT; METHADONE; NARCOTIC ANALGESIC AGENT; SODIUM CHANNEL;

ACTION POTENTIAL; ANIMAL; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; FLOW CYTOMETRY; HUMAN; MOUSE; NERVE CELL; PATCH CLAMP TECHNIQUE; PERIPHERAL NERVE; PROCEDURES;

ACTION POTENTIALS; ANALGESICS, OPIOID; ANESTHETICS, LOCAL; ANIMALS; BUPIVACAINE; CELL SURVIVAL; CELLS, CULTURED; FLOW CYTOMETRY; HUMANS; METHADONE; MICE; NEURONS; PATCH-CLAMP TECHNIQUES; PERIPHERAL NERVES; SODIUM CHANNELS;

EID: 84925555326     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aeu206     Document Type: Article

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