Direct inhibition of Ih by analgesic loperamide in rat DRG neurons

Journal of Neurophysiology

Volumn 97, Issue 5, 2007, Pages 3713-3721

  Vasilyev, Dmitry V ^a   Shan, Qin ^a   Lee, Yan ^a   Mayer, Scott C ^a   Bowlby, Mark R ^a   Strassle, Brian W ^a   Kaftan, Edward J ^a   Rogers, Kathryn E ^a   Dunlop, John ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LOPERAMIDE; ANALGESIC AGENT; HYPERPOLARIZATION ACTIVATED CATION CHANNEL; HYPERPOLARIZATION-ACTIVATED CATION CHANNEL; NALOXONE; NARCOTIC ANTAGONIST; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; HYPERPOLARIZATION; MEMBRANE CURRENT; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; SPINAL GANGLION; STEADY STATE; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; DRUG INTERACTION; ELECTROSTIMULATION; METABOLISM; METHODOLOGY; NERVE CELL; NERVE CELL INHIBITION; PATCH CLAMP; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION RESPONSE; WISTAR RAT;

ANALGESICS; ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG INTERACTIONS; ELECTRIC STIMULATION; GANGLIA, SPINAL; LOPERAMIDE; MEMBRANE POTENTIALS; NALOXONE; NARCOTIC ANTAGONISTS; NEURAL INHIBITION; NEURONS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; RATS; RATS, WISTAR;

EID: 34447298126     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00841.2006     Document Type: Article

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