Resistance to the antiproliferative effect induced by a short-chain ceramide is associated with an increase of glucosylceramide synthase, P-glycoprotein, and multidrug-resistance gene-1 in cervical cancer cells

Cancer Chemotherapy and Pharmacology

Volumn 74, Issue 4, 2014, Pages 809-817

  Gutiérrez Iglesias, Gisela ^a   Hurtado, Yamilec ^b   Palma Lara, Icela ^a   López Marure, Rebeca ^b  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^b INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

Author keywords

Ceramide; Glucosylceramide; Glucosylceramide synthase; Glycosylation; Lactosylceramide; P gp; Proliferation

Indexed keywords

2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; CERAMIDE GLUCOSYLTRANSFERASE; GLUCOSYLTRANSFERASE; LACTOSYLCERAMIDE; MORPHOLINE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN;

ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; DRUG EFFECTS; DRUG RESISTANCE; DRUG SCREENING; FEMALE; GENE; GLYCOSYLATION; HUMAN; METABOLISM; PHYSIOLOGY; TUMOR CELL CULTURE; UTERINE CERVIX TUMOR;

CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; GENES, MDR; GLUCOSYLTRANSFERASES; GLYCOSYLATION; HUMANS; LACTOSYLCERAMIDES; MORPHOLINES; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; TUMOR CELLS, CULTURED; UTERINE CERVICAL NEOPLASMS;

EID: 84925546731     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-014-2552-3     Document Type: Article

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