An optogenetic gene expression system with rapid activation and deactivation kinetics

Nature Chemical Biology

Volumn 10, Issue 3, 2014, Pages 196-202

  Motta Mena, Laura B ^a   Reade, Anna ^b   Mallory, Michael J ^c   Glantz, Spencer ^d   Weiner, Orion D ^b   Lynch, Kristen W ^c   Gardner, Kevin H ^a,e  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; HYBRID PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EL222; TRANSCRIPTION FACTOR VP16; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLUE LIGHT; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; EMBRYO; EXON SKIPPING; FLUORESCENCE MICROSCOPY; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION SYSTEM; GENE INACTIVATION; HUMAN CELL CULTURE; ILLUMINATION; IMAGE PROCESSING; IN VITRO STUDY; MAMMAL CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OPTOGENETICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN ENGINEERING; PROTEIN EXPRESSION; REPORTER GENE; STABLE TRANSFECTION; T LYMPHOCYTE; TRANSCRIPTION INITIATION; TRANSIENT TRANSFECTION; WESTERN BLOTTING; ZEBRA FISH;

BACTERIA (MICROORGANISMS); DANIO RERIO; EUKARYOTA; MAMMALIA;

ACTIVATING TRANSCRIPTION FACTORS; ANIMALS; BACTERIAL PROTEINS; CELL LINE; GENE EXPRESSION; KINETICS; LIGHT; MODELS, BIOLOGICAL; OPTOGENETICS; PROMOTER REGIONS, GENETIC; RNA-BINDING PROTEINS; T-LYMPHOCYTES; ZEBRAFISH;

EID: 84894057197     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1430     Document Type: Article

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