Propofol Attenuates Lipopolysaccharide-Induced Reactive Oxygen Species Production Through Activation of Nrf2/GSH and Suppression of NADPH Oxidase in Human Alveolar Epithelial Cells

Inflammation

Volumn 38, Issue 1, 2015, Pages 415-423

  Hsu, Hung Te ^a,c   Tseng, Yu Ting ^a   Hsu, Ya Yun ^b   Cheng, Kuang I ^c   Chou, Shah Hwa ^c   Lo, Yi Ching ^a,b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

inflammation; NADPH oxidase; Nrf2; propofol; ROS

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; PROPOFOL; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; INTRAVENOUS ANESTHETIC AGENT; NFE2L2 PROTEIN, HUMAN;

A549 CELL LINE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; INCUBATION TIME; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; ANTAGONISTS AND INHIBITORS; CELL LINE; DOSE RESPONSE; DRUG EFFECTS; LUNG ALVEOLUS; METABOLISM; RESPIRATORY TRACT MUCOSA;

ANESTHETICS, INTRAVENOUS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HUMANS; LIPOPOLYSACCHARIDES; NADPH OXIDASE; NF-E2-RELATED FACTOR 2; PROPOFOL; PULMONARY ALVEOLI; REACTIVE OXYGEN SPECIES; RESPIRATORY MUCOSA;

EID: 84925510957     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-0046-4     Document Type: Article

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