An application of target profiling analyses in the hepatotoxicity assessment of herbal medicines: Comparative characteristic fingerprint and bile acid profiling of Senecio vulgaris L. and Senecio scandens Buch.-Ham

Analytical and Bioanalytical Chemistry

Volumn 406, Issue 29, 2014, Pages 7715-7727

  Xiong, Aizhen ^a,b   Fang, Lianxiang ^a   Yang, Xiao ^a   Yang, Fan ^a   Qi, Meng ^a   Kang, Hong ^a   Yang, Li ^a   Tsim, Karl Wah Keung ^b   Wang, Zhengtao ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Bile acid; Hepatotoxicity assessment; Mass spectrometry; Natural products; Pyrrolizidine alkaloid; Target profiling

Indexed keywords

ALKALOIDS; BODY FLUIDS; MASS SPECTROMETRY; MEDICINE; METABOLITES; NITROGEN COMPOUNDS; PLANT EXTRACTS;

BILE ACID; EXPERIMENTAL ANIMALS; FINGERPRINT ANALYSIS; HEPATOTOXICITY; HISTOPATHOLOGICAL EXAMINATIONS; MULTIPLE COMPONENTS; NATURAL PRODUCTS; PYRROLIZIDINE ALKALOID;

TOXICITY;

BILE ACID; BIOLOGICAL MARKER; PYRROLIZIDINE ALKALOID;

ANIMAL; BIOASSAY; DOSE RESPONSE; DRUG-INDUCED LIVER INJURY; ELECTROSPRAY MASS SPECTROMETRY; EVALUATION STUDY; MALE; MEDICINAL PLANT; METABOLISM; PEPTIDE MAPPING; PROCEDURES; RAT; SPRAGUE DAWLEY RAT; TOXICITY; TOXICITY TESTING;

ANIMALS; BILE ACIDS AND SALTS; BIOLOGICAL ASSAY; BIOLOGICAL MARKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; MALE; PEPTIDE MAPPING; PLANTS, MEDICINAL; PYRROLIZIDINE ALKALOIDS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TOXICITY TESTS;

EID: 84925506460     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-8175-z     Document Type: Article

References (63)

1. Lv W, Piao JH, Jiang JG (2012) Expert Opin Drug Saf 11:985-1002
2. Abdualmjid RJ, Sergi C (2013) J Pharm Pharm Sci 16:376-404
3. Vanherwegham JL, Depierreux M, Tielemans C, Abramowicz D, Dratwa M, Jadoul M, Richard C, Vandervelde D, Verbeelen D, Vanhaelen-Fastre R (1993) Lancet 341:387-391
4. Ernst E (2003) Can J Cardiol 19:818-827
5. Chan TYK, Tam HP, Lai CK, Chan AYW (2005) Ther Drug Monit 27:53-57
6. Seeff LB (2007) Clin Liver Dis 11:577-596
7. Jordan SA, Cunningham DG, Marles RJ (2010) Toxicol Appl Pharmacol 243:198-216
8. Shaw D (2010) Planta Med 76:2012-2018
9. Efferth T, Kaina B (2011) Curr Drug Metab 12:989-996
10. Ma B, Li N, Lin G (2012) Curr Drug Metab 13:652-658
11. Chang WT, Thissen U, Ehlert KA, Koek MM, Jellema RJ, Hankemeier T, Van der Greef J, Wang M (2006) Planta Med 72:458-467
12. Zhang Y, Li F, Huang F, Xie G, Wei R, Chen T, Liu J, Zhao A, Jia W (2014) J Sep Sci 37:731-737
13. Roeder E (1995) Pharmazie 50:83-98
14. Roeder E (2000) Pharmazie 55:711-726
15. International Programme on Chemical Safety (1988) Pyrrolizidine alkaloids. Environmental health criteria 80.WHO, Geneva
16. Xiong AZ, Yang L, He YQ, Zhang F, Wang J, Han H, Wang CH, Bligh SWA, Wang ZT (2009) Rapid Commun Mass Spectrom 23:3907-3916
17. Zhou Y, Li N, Choi FF, Qiao CF, Song JZ, Li SL, Liu X, Cai ZW, Fu PP, Lin G, Xu HX (2010) Anal Chim Acta 681:33-40
18. Ruan J, Li N, Xia Q, Fu PP, Peng S, Ye Y, Lin G (2012) J Mass Spectrom 47:331-337
19. Qi M, Xiong AZ, Geng F, Yang L, Wang ZT (2012) J Sep Sci 35:1470-1478
20. Ji S, Wang Q, Qiao X, Guo HC, Yang YF, Bo T, Xiang C, Guo DA, Ye M (2014) J Pharm Biomed Anal 90:15-26
21. International Programme on Chemical Safety (1989) Pyrrolizidine alkaloids health and safety guide. Health and safety guide no. 26. WHO, Geneva
22. Dai N, Yu YC, Ren TH, Wu JG, Jiang Y, Shen LG, Zhang J (2007) World J Gastroenterol 13:1628-1631
23. Altaee MY, Mahmood MH (1998) East Mediterr Health J 4:142-148
24. Kakar F, Akbarian Z, Leslie T, Mustafa ML, Watson J, van Egmond HP, Omar MF, Mofleh J (2010) J Toxicol 2010:313280
25. Bane A, Seboxa T, Mesfin G, Ali A, Tsegaye YW, Tensae MG, Selassie S, Haile T (2012) Eth Med J 50:9-16
26. Lewis CJ (2001) U.S. Food and Drug Administration Web site. http://www.fda.gov/Food/RecallsOutbreaksEmergencies/SafetyAlertsAdvisories/ucm111219.htm. Accessed 6 July 6 2001
27. State Pharmacopoeia Commission of the P. R. China (2010) Pharmacopoeia of the People's Republic of China 2010. China Medicinal Science and Technology Press, Beijing
28. Lessard P, Wilson WD, Olander HJ, Rogers QR, Mendel VE (1986) Am J Vet Res 47:1776-1780
29. Mendel VE, Witt MR, Gitchell BS, Gribble DN, Rogers QR, Segall HJ, Knight HD (1988) Am J Vet Res 49:572-578
30. Sutherland RJ, Deol HS, Hood PJ (1992) Vet Clin Pathol 21:51-56
31. Yan CC, Huxtable RJ (1995) Toxicol Appl Pharmacol 130:132-139
32. Xiong AZ, Yang F, Fang LX, Yang L, He YQ, Wan YY, Xu Y, Qi M, Wang XL, Yu K, Tsim KW, Wang ZT (2014) Chem Res Toxicol 27(5):775-786
33. Chen J, Deng W, Wang J, Shao Y, Ou M, Ding M (2013) Int J Gynaecol Obstet 1:5-8
34. Lake AD, Novak P, Shipkova P, Aranibar N, Robertson D, Reily MD, Lu Z, Lehman-McKeeman LD, Cherrington NJ (2013) Toxicol Appl Pharmacol 2:132-140
35. Yang L, Xiong AZ, He YQ, Wang ZY, Wang CH, Wang ZT, Li W, Yang L, Hu ZB (2008) Chem Res Toxicol 21:2280-2288
36. Yang F, Xu Y, Xiong AZ, He YQ, Yang L, Wan YJY, Wang ZT (2012) J Ethnopharmacol 144:599-604
37. Ortiz Cansado A, Crespo Valadés E, Morales Blanco P, Sáenz de Santamaría J, González Campillejo JM, Ruiz Téllez T (1995) Gastroenterol Hepatol 18:413-416
38. Vilar JH, García M, Cabrera P (2000) Gastroenterol Hepatol 23:285-286
39. Li SL, Lin G, Fu PP, Chan CL, Li M, Jiang ZH, Zhao ZZ (2008) Rapid Commun Mass Spectrom 22:591-602
40. Zhang F, Wang CH, Wang W, Chen LX, Ma HY, Zhang CF, Zhang M, Bligh SW, Wang ZT (2008) Phytochem Anal 19:25-31
41. Jones AJ, Culvenor CCJ, Smith LW (1982) Aust J Chem 35(6):1173-1178
42. Segall HJ, Dallas TL (1983) Phytochemistry 22(5):1271-1273
43. Zalkow LH, Asibal CF, Glinski JA, Bonetti SJ, Gelbaum LT, VanDerveer D, Powis G (1988) J Nat Prod 51(4):690-702
44. Witte L, Ernsta L, Wrayb V, Hartmann T (1992) Phytochemistry 31(3):1027-1028
45. Noorwala M, Mohammad F, Ahmad V, Sener B, Ergun F, Deliorman D (2000) Fitoterapia 71(5):618-620
46. Xiong AZ, Yang L, Ji LL, Wang ZY, Yang XJ, Chen Y, Wang XL, Wang CH, Wang ZT (2012) Metabolomics 8:614-623
47. Wiklund S, Johansson E, Sjöström L, Mellerowicz EJ, Edlund U, Shockcor JP, Gottfries J, Moritz T, Trygg J (2008) Anal Chem 80:115-122
48. Claudel R, Steals B, Kuipers F (2005) Arterioscler, Thromb, Vasc Biol 25:2020-2030
49. Calkin AC, Tontonoz P (2012) Nat Rev Mol Cell Biol 13:213-224
50. Nicolaou M, Andress EJ, Zolnerciks JK, Dixon PH, Williamson C, Linton KJ (2012) J Pathol 226:300-315
51. Wu XP, Chai J, Chen WS (2009) Acad J Sec Mil Med Univ 30:1398-1401
52. Abu-Hayyeh S, Papacleovoulou G, Lövgren-Sandblom A, Tahir M, Oduwole O, Jamaludin NA, Ravat S, Nikolova V, Chambers J, Selden C, Rees M, Marschall HU, Parker MG, Williamson C (2013) Hepatology 57:716-726
53. Yang F, Huang X, Yi TS, Yen Y, Moore DD, Huang WD (2007) Cancer Res 67:863-867
54. Pircher PC, Kitto JL, Petrowski ML, Tangirala RK, Bischoff ED, Schulman IG, Westin SK (2003) J Biol Chem 278(30):27703-27711
55. Hadžić N, Bull LN, Clayton PT, Knisely AS (2012) World J Gastroenterol 18(25):3322-3326
56. Stieger B, Fattinger K, Madon J, Kullak-Ublick GA, Meier PJ (2000) Gastroenterology 118:422-430
57. Cao J, Huang L, Liu Y, Hoffman T, Stieger B, Meier PJ, Vore M (2001) Hepatology 33:140-147
58. Soroka CJ, Lee JM, Azzaroli F, Boyer JL (2001) Hepatology 33:783-791
59. Teng S, Piquette-Miller M (2007) Br J Pharmacol 151:367-376
60. Zollner G, Fickert P, Zenz R, Fuchsbichler A, Stumptner C, Kenner L, Ferenci P, Stauber RE, Krejs GJ, Denk H, Zatloukal K, Trauner M (2004) Hepatology 33:633-646
61. Geier A, Dietrich CG, Gerloff T, Haendly J, Kullak-Ublick GA, Stieger B, Meier PJ, Matern S, Gartung C (2003) Biochim Biophys Acta 1609:87-94
62. DeLeve LD, McCuskey RS, Wang X, Hu L, McCuskey MK, Epstein RB, Kanel GC (1999) Hepatology 29:1779-1791
63. Lin G, Wang JY, Li N, Li M, Gao H, Ji Y, Zhang F, Wang H, Zhou Y, Ye Y, Xu HX, Zheng J (2011) J Hepatol 54:666-673