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Volumn 11, Issue 6, 2012, Pages 985-1002

Typical toxic components in traditional Chinese medicine

Author keywords

Chemical structure; Toxic ingredients; Toxicology; Traditional Chinese medicine

Indexed keywords

ACONITINE; ARISTOLOCHIC ACID; ATRACTYLOSIDE; BORNEOL; CAMPHOR; CANTHARIDIN; CARDIAC GLYCOSIDE; CEVADINE; COLCHICINE; COPPER; DAURICINE; EPHEDRINE; ESSENTIAL OIL; GLYCOSIDE; GOSSYPOL; HERBACEOUS AGENT; LEAD; LEVO INDOSPICINE; MATRINE; MENTHOL; MERCURY; MIMOSINE; PYRROLIZIDINE ALKALOID; RESIN; SAPONIN; SCOPOLAMINE; STRYCHNINE; TRIPTOLIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; WILFORDINE;

EID: 84867818974     PISSN: 14740338     EISSN: 1744764X     Source Type: Journal    
DOI: 10.1517/14740338.2012.726610     Document Type: Review
Times cited : (21)

References (103)
  • 1
    • 84891738576 scopus 로고    scopus 로고
    • Analyzing the toxicity of TCM and the rational usage of toxic TCM
    • Ji CH, Zhang XF, Yan JH. Analyzing the toxicity of TCM and the rational usage of toxic TCM. HeNan Tradit Chin Med 2008;28:69-70
    • (2008) HeNan Tradit Chin Med , vol.28 , pp. 69-70
    • Ji, C.H.1    Zhang, X.F.2    Yan, J.H.3
  • 2
    • 84891747076 scopus 로고    scopus 로고
    • The knowledge and research of the traditional Chinese medicine toxicity
    • Jin M. The knowledge and research of the traditional Chinese medicine toxicity. J Med Pharm Chin Minorities 2005;z1:101-2
    • (2005) J Med Pharm Chin Minorities , vol.Z1 , pp. 101-102
    • Jin, M.1
  • 3
    • 78751486866 scopus 로고    scopus 로고
    • Perspectives for globalized natural medicines
    • Efferth T. Perspectives for globalized natural medicines. Chin J Nat Med 2011;9:0001-6
    • (2011) Chin J Nat Med , vol.9 , pp. 0001-6
    • Efferth, T.1
  • 4
    • 84891736308 scopus 로고    scopus 로고
    • Chinese medicine toxicology research
    • Wu FH, Huang MH. Chinese medicine toxicology research. Chin J Mod Drug Appl 2009;3:201-2
    • (2009) Chin J Mod Drug Appl , vol.3 , pp. 201-202
    • Wu, F.H.1    Huang, M.H.2
  • 5
    • 78649908675 scopus 로고    scopus 로고
    • Toxicological Risks of Chinese Herbs
    • Shaw D. Toxicological Risks of Chinese Herbs. Planta Med 2010;76:2012-18
    • (2010) Planta Med , vol.76 , pp. 2012-2018
    • Shaw, D.1
  • 6
    • 77949368190 scopus 로고    scopus 로고
    • Assessment of herbal medicinal products: Challenges, and opportunities to increase the knowledge base for safety assessment
    • Scott AJ, David GC, Robin JM. Assessment of herbal medicinal products: challenges, and opportunities to increase the knowledge base for safety assessment. Toxicol Appl Pharmacol 2010;243:198-216
    • (2010) Toxicol Appl Pharmacol , vol.243 , pp. 198-216
    • Scott, A.J.1    David, G.C.2    Robin, J.M.3
  • 7
    • 77954101025 scopus 로고    scopus 로고
    • Classified study on the toxicity of 615 kinds of common traditional chinese medicines
    • He XY. Classified study on the toxicity of 615 kinds of common traditional chinese medicines. Chin Pharm 2007;18:2392-3
    • (2007) Chin Pharm , vol.18 , pp. 2392-2393
    • He, X.Y.1
  • 8
    • 84891742359 scopus 로고    scopus 로고
    • Research progress on toxic ingredients of chinese herbal medicine with reproductive toxicity
    • Zhou Y. Research progress on toxic ingredients of chinese herbal medicine with reproductive toxicity. Chin J Exp Tradit Med Formulae 2009;15:97-9
    • (2009) Chin J Exp Tradit Med Formulae , vol.15 , pp. 97-99
    • Zhou, Y.1
  • 9
    • 0034835805 scopus 로고    scopus 로고
    • Chips and Qi: Microcomponent-based analysis in traditional Chinese medicine
    • Maria C, Thomas L, Shanti M, et al. Chips and Qi: microcomponent-based analysis in traditional Chinese medicine. Fresenius J Anal Chem 2001;371:190-4
    • (2001) Fresenius J Anal Chem , vol.371 , pp. 190-194
    • Maria, C.1    Thomas, L.2    Shanti, M.3
  • 10
  • 11
    • 84891748039 scopus 로고    scopus 로고
    • The process of study of Xanthium toxic ingredients and process technology
    • Cao LP, Zang ZH, Liao HX, et al. The process of study of Xanthium toxic ingredients and process technology. Chin Med Herad 2008;5:22-3
    • (2008) Chin Med Herad , vol.5 , pp. 22-23
    • Cao, L.P.1    Zh, Z.2    Liao, H.X.3
  • 12
    • 84867826344 scopus 로고    scopus 로고
    • Pinellia ternate pedate pinellia rhizome
    • Beijing
    • Jiang NQ. Pinellia ternate pedate pinellia rhizome. Chin Press Tradit Chin Med; Beijing: 2001. p. 91-5
    • (2001) Chin Press Tradit Chin Med , pp. 91-95
    • Jiang, N.Q.1
  • 13
    • 23144457967 scopus 로고
    • Irritating substance of Pinelliae ternate
    • Masako S. Irritating substance of Pinelliae ternate. Arzneim Forsch 1969;19:1307-8
    • (1969) Arzneim Forsch , vol.19 , pp. 1307-1308
    • Masako, S.1
  • 14
    • 84891739024 scopus 로고    scopus 로고
    • Study on the toxicities of pinellia and the way to detoxicate
    • Tong X. Study on the toxicities of pinellia and the way to detoxicate. Inf Tradit Chin Med 2009;26:12-15
    • (2009) Inf Tradit Chin Med , vol.26 , pp. 12-15
    • Tong, X.1
  • 15
    • 0009183120 scopus 로고
    • Structure of new alkaloid wilforidine from tripterygium wilfordii
    • He ZS, Hong SH. Structure of new alkaloid wilforidine from tripterygium wilfordii. Acta Chim Sinica 1985;43:593-6
    • (1985) Acta Chim Sinica , vol.43 , pp. 593-596
    • He, Z.S.1    Hong, S.H.2
  • 16
    • 0001103114 scopus 로고
    • Structures of wilfortrine and neowilforine from tripterygium wilfordii Hook.f
    • He ZS, Li Y. Fang SD, et al. structures of wilfortrine and neowilforine from tripterygium wilfordii Hook.f. Acta Chim Sinica 1989;47:178-81
    • (1989) Acta Chim Sinica , vol.47 , pp. 178-181
    • He, Z.S.1    Li, Y.2    Fang, S.D.3
  • 17
    • 0000315185 scopus 로고
    • Struetures of wilforgine, wilforzine and wilformine from tripterygium wilfordii
    • He ZS, Li Y, Fang SD, et al. Struetures of wilforgine, wilforzine and wilformine from tripterygium wilfordii. Acta Chim Sinica 1987;45:510-13
    • (1987) Acta Chim Sinica , vol.45 , pp. 510-513
    • He, Z.S.1    Li, Y.2    Fang, S.D.3
  • 18
    • 84867820537 scopus 로고    scopus 로고
    • The effect and toxicity of aconitine
    • Zhou YH, Hu HT. The effect and toxicity of aconitine. Henan Tradit Chin Med 2008;27:89-90
    • (2008) Henan Tradit Chin Med , vol.27 , pp. 89-90
    • Zhou, Y.H.1    Hu, H.T.2
  • 19
    • 84891745170 scopus 로고
    • The ultrastructural localization of succinate dehydrogenase in mitochondria of the heart tissue from the aconitine poisoning rat
    • Li H, Liu MJ, Chen NZ. The ultrastructural localization of succinate dehydrogenase in mitochondria of the heart tissue from the aconitine poisoning rat. Chin J Forensic Med 1988;3:199-201
    • (1988) Chin J Forensic Med , vol.3 , pp. 199-201
    • Li, H.1    Liu, M.J.2    Chen, N.Z.3
  • 20
    • 84891745489 scopus 로고
    • The ultrastructural localization of cytochrome c oxidase in mitochondria of the heart tissue from the aconitine poisoning rat(II)
    • Li H, Chen NZ, Liu MJ. The ultrastructural localization of cytochrome c oxidase in mitochondria of the heart tissue from the aconitine poisoning rat(II). Chin J Forensic Med 1988;3:202-4
    • (1988) Chin J Forensic Med , vol.3 , pp. 202-204
    • Li, H.1    Chen, N.Z.2    Liu, M.J.3
  • 21
    • 84891749164 scopus 로고
    • The histo-and cyto-chemical demonstration of NADH dehydrogenase in myocardium of aconitine poisoning rat
    • Liang QR, Liu MJ, Hu BW. The histo-and cyto-chemical demonstration of NADH dehydrogenase in myocardium of aconitine poisoning rat. Chin J Forensic Med 1991;6:84-6
    • (1991) Chin J Forensic Med , vol.6 , pp. 84-86
    • Liang, Q.R.1    Liu, M.J.2    Hu, B.W.3
  • 22
    • 84891736967 scopus 로고
    • The histo-and cyto-chemistry study of myocardial lactic dehydrogenase of the aconitine poisoning rats
    • Liang QR, Liu MJ, Hu BW. The histo-and cyto-chemistry study of myocardial lactic dehydrogenase of the aconitine poisoning rats. Chin J Forensic Med 1991;6:140-1
    • (1991) Chin J Forensic Med , vol.6 , pp. 140-141
    • Liang, Q.R.1    Liu, M.J.2    Hu, B.W.3
  • 23
    • 84891746436 scopus 로고    scopus 로고
    • Clinical analysis of acute poisoning aconitine-62 cases report
    • Yu ZS, Cili ZS. Clinical analysis of acute poisoning aconitine-62 cases report. Chin J Med Guide 2009;11:882-3
    • (2009) Chin J Med Guide , vol.11 , pp. 882-883
    • Yu, Z.S.1    Cili, Z.S.2
  • 24
    • 70349761212 scopus 로고    scopus 로고
    • Aconitum in traditional chinese medicine - A valuable drug or an unpredictable risk
    • Judith S, Ming ZB, Sonja P, et al. Aconitum in traditional chinese medicine-a valuable drug or an unpredictable risk. J Ethnopharmacol 2009;126:18-30
    • (2009) J Ethnopharmacol , vol.126 , pp. 18-30
    • Judith, S.1    Ming, Z.B.2    Sonja, P.3
  • 25
    • 74749086951 scopus 로고    scopus 로고
    • The toxicity of aconitum alkaloids on cardiocytes and the progress of its research using the methods of molecular toxicology
    • Liu Y, Zhang SW. The toxicity of aconitum alkaloids on cardiocytes and the progress of its research using the methods of molecular toxicology. Chin J Forensic Med 2009;24:398-401
    • (2009) Chin J Forensic Med , vol.24 , pp. 398-401
    • Liu, Y.1    Zhang, S.W.2
  • 26
    • 0141557541 scopus 로고    scopus 로고
    • Dissociation of cytochrome c from the inner mitochondrial membrane during cardiac ischemia
    • Czerski LW, Szweda PA, Szweda LI. Dissociation of cytochrome c from the inner mitochondrial membrane during cardiac ischemia. J Biol Chem 2003;278:34499-504
    • (2003) J Biol Chem , vol.278 , pp. 34499-34504
    • Czerski, L.W.1    Szweda, P.A.2    Szweda, L.I.3
  • 27
    • 0030444976 scopus 로고    scopus 로고
    • Progesterone modulation of diazepam withdrawal syndrome in mice
    • Pesce ME, Acevedo X, Pinardi G, et al. Progesterone modulation of diazepam withdrawal syndrome in mice. Pharm Toxicol 1996;79:331-3
    • (1996) Pharm Toxicol , vol.79 , pp. 331-333
    • Pesce, M.E.1    Acevedo, X.2    Pinardi, G.3
  • 28
    • 74049118074 scopus 로고    scopus 로고
    • Progressive studies on toxity of Strychons nux vomica
    • Jia XX, Li W, Li JS, et al. Progressive studies on toxity of Strychons nux vomica. Chin JChin Mater Med 2009;34:2396-9
    • (2009) Chin JChin Mater Med , vol.34 , pp. 2396-2399
    • Jia, X.X.1    Li, W.2    Li, J.S.3
  • 29
    • 67249149777 scopus 로고    scopus 로고
    • Advance on pharmacologic actions, toxicity and pharmacokinetics of pyrrolizidine alkaloids
    • Gao JG. Wang CG, Li Y et al. Advance on pharmacologic actions, toxicity and pharmacokinetics of pyrrolizidine alkaloids. China J Chin Mater Med 2009;34:506-11
    • (2009) China J Chin Mater Med , vol.34 , pp. 506-511
    • Gao, J.G.1    Wang, C.G.2    Li, Y.3
  • 30
    • 84891741433 scopus 로고    scopus 로고
    • Traditional chinese medicine containing pyrrolizidine alkaloids and hepatic veno-occlusive disease
    • Wang Q, Lu CM, Guo T. Traditional chinese medicine containing pyrrolizidine alkaloids and hepatic veno-occlusive disease. Chin J Clin Gastroenterol 2008;20:22-5
    • (2008) Chin J Clin Gastroenterol , vol.20 , pp. 22-25
    • Wang, Q.1    Lu, C.M.2    Guo, T.3
  • 31
    • 80051521189 scopus 로고    scopus 로고
    • Research progress of especial toxicity and of pyrrolizidine alkaloids
    • Han JY, Liang AH, Gao SG. Research progress of especial toxicity and of pyrrolizidine alkaloids. China J Chin Mater Med 2011;36:1397-401
    • (2011) China J Chin Mater Med , vol.36 , pp. 1397-1401
    • Han, J.Y.1    Liang, A.H.2    Gao, S.G.3
  • 32
    • 0037548796 scopus 로고
    • Chemical studies on active principles of veratrum stenophyllum
    • Liang GY, Sun NJ. Chemical studies on active principles of veratrum stenophyllum. Acta Pharm Sinica 1984;19:131-6
    • (1984) Acta Pharm Sinica , vol.19 , pp. 131-136
    • Liang, G.Y.1    Sun, N.J.2
  • 33
    • 84891744561 scopus 로고    scopus 로고
    • The advances in studies of Veratrums from China
    • Mao XF, Shi ZC, Wang YZ. The advances in studies of Veratrums from China. Anim toxicol 2003;18:17-21
    • (2003) Anim Toxicol , vol.18 , pp. 17-21
    • Mao, X.F.1    Shi, Z.C.2    Wang, Y.Z.3
  • 34
    • 84891749021 scopus 로고    scopus 로고
    • The pharmacology and toxicology research progress of veratrine
    • Zhao Y, Lu GC, Zhang WD, et al. The pharmacology and toxicology research progress of veratrine. Tradit Chin Drug Res Clin Pharm 2008;19:240-2
    • (2008) Tradit Chin Drug Res Clin Pharm , vol.19 , pp. 240-242
    • Zhao, Y.1    Lu, G.C.2    Zhang, W.D.3
  • 35
    • 4444244492 scopus 로고    scopus 로고
    • Fatal Datura poisoning: Identification of atropine and scopolamine by high performance liquid chromatography/photodiode array/mass spectrometry
    • Steenkamp PA, Harding NM, Heerden FR, et al. Fatal Datura poisoning: identification of atropine and scopolamine by high performance liquid chromatography/photodiode array/mass spectrometry. Forensic Sci Int 2004;145:31-9
    • (2004) Forensic Sci Int , vol.145 , pp. 31-39
    • Steenkamp, P.A.1    Harding, N.M.2    Heerden, F.R.3
  • 37
    • 1542286774 scopus 로고    scopus 로고
    • Molecular adaptation of chrysochus leaf beetles to toxic compounds in their food plants
    • Estelle L, Susanne D. Molecular adaptation of chrysochus leaf beetles to toxic compounds in their food plants. Mol Biol Evol 2004;21:218-21
    • (2004) Mol Biol Evol , vol.21 , pp. 218-221
    • Estelle, L.1    Susanne, D.2
  • 38
    • 84871575924 scopus 로고    scopus 로고
    • People's Med Publishing House; Beijing
    • Yao XS. Natural pharmaceutical chemistry. People's Med Publishing House; Beijing: 2002. p. 320-3
    • (2002) Natural Pharmaceutical Chemistry , pp. 320-323
    • Yao, X.S.1
  • 39
    • 77958194046 scopus 로고    scopus 로고
    • Study on hepatotoxicity on rats caused by crude extracts of total saikosaponins and correlation with oxidative damage mechanism
    • Huang W, Sun R. Study on hepatotoxicity on rats caused by crude extracts of total saikosaponins and correlation with oxidative damage mechanism. Chin J Chin Mater Med 2010;35:1745-9
    • (2010) Chin J Chin Mater Med , vol.35 , pp. 1745-1749
    • Huang, W.1    Sun, R.2
  • 40
    • 84891742214 scopus 로고    scopus 로고
    • Rats' hepatic and renal toxicity of total Saponins from panax notoginseng
    • Han G, Sun HY, Dong YS, et al. Rats' hepatic and renal toxicity of total Saponins from panax notoginseng. Chin J New Drug 2006;15:2114-18
    • (2006) Chin J New Drug , vol.15 , pp. 2114-2118
    • Han, G.1    Sun, H.Y.2    Dong, Y.S.3
  • 41
    • 77953850923 scopus 로고    scopus 로고
    • Toxic effects of Panax notoginseng saponins on cardiac hemodynamics in rats
    • Xu J, Peng SQ, Yan CH, et al. Toxic effects of Panax notoginseng saponins on cardiac hemodynamics in rats. Chin J New Drugs 2009;18:349-52
    • (2009) Chin J New Drugs , vol.18 , pp. 349-352
    • Xu, J.1    Peng, S.Q.2    Yan, C.H.3
  • 42
    • 84867758952 scopus 로고    scopus 로고
    • Advances in studies on toxicity and modern toxicology research of fructus xanthii
    • Zhang TT, Yan LC, Zhao JL, et al. Advances in studies on toxicity and modern toxicology research of fructus xanthii. Med Recapitulate 2010;16:2814-18
    • (2010) Med Recapitulate , vol.16 , pp. 2814-2818
    • Zhang, T.T.1    Yan, L.C.2    Zhao, J.L.3
  • 45
    • 84891743341 scopus 로고    scopus 로고
    • Research Progress on Ribosome-inactivating Proteins
    • Yuan Y, Mao Y. Research Progress on Ribosome-inactivating Proteins. Nat Prod Res Dev 2007;19:169-74
    • (2007) Nat Prod Res Dev , vol.19 , pp. 169-174
    • Yuan, Y.1    Mao, Y.2
  • 46
    • 4043133131 scopus 로고    scopus 로고
    • Ribosome-inactivating proteins
    • Fiorenzo S. Ribosome-inactivating proteins. Toxicon 2004;44:371-83
    • (2004) Toxicon , vol.44 , pp. 371-383
    • Fiorenzo, S.1
  • 47
    • 38349143012 scopus 로고    scopus 로고
    • Ribosome-inactivity protein and its application in plant anti-fungal disease genetic
    • Shan LB. Ribosome-inactivity protein and its application in plant anti-fungal disease genetic. Prog Biotechnol 2000;20:74-8
    • (2000) Prog Biotechnol , vol.20 , pp. 74-78
    • Shan, L.B.1
  • 48
    • 84891747329 scopus 로고    scopus 로고
    • Transport of ribosome-inactivating proteins in the Cell
    • Feng W, Zhan JB. Transport of ribosome-inactivating proteins in the Cell. Chin J Cell Biol 2005;27:761-2
    • (2005) Chin J Cell Biol , vol.27 , pp. 761-762
    • Feng, W.1    Zhan, J.B.2
  • 49
    • 84867756654 scopus 로고    scopus 로고
    • Recent advance on the structure-function relationship of trichosanthin and its cell entry
    • Huang YL, Huang LM. Recent advance on the structure-function relationship of trichosanthin and its cell entry. Lishizhen Med Mater Med Res 2010;21:268-9
    • (2010) Lishizhen Med Mater Med Res , vol.21 , pp. 268-269
    • Huang, Y.L.1    Huang, L.M.2
  • 50
    • 84891737391 scopus 로고    scopus 로고
    • Survey of venom protein, peptide and amino acids in natural drug
    • Chen JB, Chen HL, Wang GZ, et al. Survey of venom protein, peptide and amino acids in natural drug. Chin Tradit Pat Med 2001;23:751-4
    • (2001) Chin Tradit Pat Med , vol.23 , pp. 751-754
    • Chen, J.B.1    Chen, H.L.2    Wang, G.Z.3
  • 52
    • 0016669467 scopus 로고
    • Cytoccidal activity of cytotoxin from Indian cobra and its derivatives against experimental tumors
    • Lwaguchi TM, Hayash K, Sakurai Y. Cytoccidal activity of cytotoxin from Indian cobra and its derivatives against experimental tumors. Toxicon 1975;13:101-2
    • (1975) Toxicon , vol.13 , pp. 101-102
    • Lwaguchi, T.M.1    Hayash, K.2    Sakurai, Y.3
  • 53
    • 54949090720 scopus 로고    scopus 로고
    • Animal toxins and the kidney
    • Sitprija V. Animal toxins and the kidney. Nat Clin Pract Nephrol 2008;4:616-27
    • (2008) Nat Clin Pract Nephrol , vol.4 , pp. 616-627
    • Sitprija, V.1
  • 54
    • 77957919155 scopus 로고    scopus 로고
    • Investigation progress about animal reproductive toxicity of gossypol
    • Ni M, Yuan H. Investigation progress about animal reproductive toxicity of gossypol. Chin Anim Husbandry Vet Med 2008;35:144-5
    • (2008) Chin Anim Husbandry Vet Med , vol.35 , pp. 144-145
    • Ni, M.1    Yuan, H.2
  • 55
    • 84891739661 scopus 로고    scopus 로고
    • Harmful effect of gossypol in cottonseed meal and research progress on the process of detoxifcation
    • Wang DM, Gou SX, Liang YX. Harmful effect of gossypol in cottonseed meal and research progress on the process of detoxifcation. Hubei Agric Sci 2009;48:487-93
    • (2009) Hubei Agric Sci , vol.48 , pp. 487-493
    • Wang, D.M.1    Gou, S.X.2    Liang, Y.X.3
  • 56
    • 84891743803 scopus 로고    scopus 로고
    • The research progress of aristolochic acid renal toxicity in Chinese medicine
    • Hu Y, Jiang ZZ, Zhang LY. The research progress of aristolochic acid renal toxicity in Chinese medicine. Central S Pharm 2011;9:447-50
    • (2011) Central S Pharm , vol.9 , pp. 447-450
    • Hu, Y.1    Jiang, Z.Z.2    Zhang, L.Y.3
  • 57
    • 84891746538 scopus 로고    scopus 로고
    • Role of endothelial cells injury in aristolochic acid nephropathy and its related mechanism
    • Luo J, Zhao HJ, Li XZ. Role of endothelial cells injury in aristolochic acid nephropathy and its related mechanism. J Appl Clin Pediatr 2011;26:316-18
    • (2011) J Appl Clin Pediatr , vol.26 , pp. 316-318
    • Luo, J.1    Zhao, H.J.2    Li, X.Z.3
  • 58
    • 84891748873 scopus 로고    scopus 로고
    • Effect of Aristolochic Acid on human umbilical veinendothelial cell apoptosis
    • Shi H, Feng JM, Deng JY. Effect of Aristolochic Acid on human umbilical veinendothelial cell apoptosis. China J Mod Med 2011;21:951-8
    • (2011) China J Mod Med , vol.21 , pp. 951-958
    • Shi, H.1    Feng, J.M.2    Deng, J.Y.3
  • 59
    • 84891745799 scopus 로고    scopus 로고
    • The main toxicity and mechanism of aristolochic acid
    • Xiong JY, Tan ZH. The main toxicity and mechanism of aristolochic acid. J Sichuan Tradit Chin Med 2011;29:39-42
    • (2011) J Sichuan Tradit Chin Med , vol.29 , pp. 39-42
    • Xiong, J.Y.1    Zh, T.2
  • 60
    • 84891747491 scopus 로고    scopus 로고
    • Poisoning of traditional Chinese mineral medicines containing heavy metal: Clinical presentation and management
    • Wang DX, Zhu XL. Poisoning of traditional Chinese mineral medicines containing heavy metal: clinical presentation and management. Adv Drug React J 2007;9:43-5
    • (2007) Adv Drug React J , vol.9 , pp. 43-45
    • Wang, D.X.1    Zhu, X.L.2
  • 61
    • 77949861990 scopus 로고    scopus 로고
    • Analysis of the adverse reactions induced by natural product derived drugs
    • Zeng ZP, Jiang JG. Analysis of the adverse reactions induced by natural product derived drugs. Br J Pharmacol 2010;159:1374-91
    • (2010) Br J Pharmacol , vol.159 , pp. 1374-1391
    • Zeng, Z.P.1    Jiang, J.G.2
  • 62
    • 84891740827 scopus 로고    scopus 로고
    • Discussion of the features of non-prescription drugs of traditional chinese medicine and the ways in their safe use
    • Xia DS, Cheng G, Zhang L. Discussion of the features of non-prescription drugs of traditional chinese medicine and the ways in their safe use. Chin J Pharmacoepidemiol 2011;20:299-302
    • (2011) Chin J Pharmacoepidemiol , vol.20 , pp. 299-302
    • Xia, D.S.1    Cheng, G.2    Zhang, L.3
  • 63
    • 84891748900 scopus 로고    scopus 로고
    • The method and mechanism of Chinese medicine processing
    • Wang JS. The method and mechanism of Chinese medicine processing. China Foreign Med Treat 2011;30:137
    • (2011) China Foreign Med Treat , vol.30 , pp. 137
    • Wang, J.S.1
  • 64
    • 84891737486 scopus 로고    scopus 로고
    • Analysis on clinical research method of the cause of ADR induced by traditional Chinese medicine
    • Guo XF, Li JT. Analysis on clinical research method of the cause of ADR induced by traditional Chinese medicine. J Guangzhou Univ Tradit Chin Med 2010;27:300-6
    • (2010) J Guangzhou Univ Tradit Chin Med , vol.27 , pp. 300-306
    • Guo, X.F.1    Li, J.T.2
  • 65
    • 84891737171 scopus 로고    scopus 로고
    • Analysis on research method of the cause of ADR induced by traditional Chinese medicine injection
    • Zhang N, Zhu WT, Wang TZ, et al. Analysis on research method of the cause of ADR induced by traditional Chinese medicine injection. China Pharm 2010;21:1820-2
    • (2010) China Pharm , vol.21 , pp. 1820-1822
    • Zhang, N.1    Zhu, W.T.2    Wang, T.Z.3
  • 66
    • 84891744944 scopus 로고    scopus 로고
    • On the cancellation of the medicinal standards of aristolochic acid-containing Chinese Medicines
    • Cen XN. On the cancellation of the medicinal standards of aristolochic acid-containing Chinese Medicines. Liuzhou Med 2008;21:201-3
    • (2008) Liuzhou Med , vol.21 , pp. 201-203
    • Cen, X.N.1
  • 67
    • 77956262888 scopus 로고    scopus 로고
    • State Pharmacopoeia Commission of the P.R.China China Medicinal Science and Technology Press; Beijing
    • State Pharmacopoeia Commission of the P.R.China. Pharmacopoeia of the People's Republic of China (Chinese Edition 2010). China Medicinal Science and Technology Press; Beijing: 2010. p. 1
    • (2010) Pharmacopoeia of the People's Republic of China (Chinese Edition 2010) , pp. 1
  • 68
    • 80052616610 scopus 로고    scopus 로고
    • Pyrrolizidine alkaloids-containing Chinese medicines in the Chinese Pharmacopoeia and related safety concerns
    • Tang J, Hattori M. Pyrrolizidine alkaloids-containing Chinese medicines in the Chinese Pharmacopoeia and related safety concerns. Acta Pharmaceutica Sinica 2011;46:762-72
    • (2011) Acta Pharmaceutica Sinica , vol.46 , pp. 762-772
    • Tang, J.1    Hattori, M.2
  • 69
    • 33748988327 scopus 로고    scopus 로고
    • Studies on apoptosis in myocardial cells after aconitine poisoning in mice
    • Lei HC, Song DJ, Yi JH, et al. Studies on apoptosis in myocardial cells after aconitine poisoning in mice. Chin J Ind Med 2004;17:373-4
    • (2004) Chin J Ind Med , vol.17 , pp. 373-374
    • Lei, H.C.1    Song, D.J.2    Yi, J.H.3
  • 70
    • 30544444758 scopus 로고    scopus 로고
    • Embryotoxicity and teratogenecity of Aconitum in Rats
    • Xiao K, Li HX. Embryotoxicity and teratogenecity of Aconitum in Rats. J Chin Pharm Univ 2005;36:567-71
    • (2005) J Chin Pharm Univ , vol.36 , pp. 567-571
    • Xiao, K.1    Li, H.X.2
  • 71
    • 84891740163 scopus 로고    scopus 로고
    • Effects of ouabain and aconitine on sodium currents of isolated guinea pig and rat ventricular myocytes
    • Gong DM, Zou XL, Bai YN. Effects of ouabain and aconitine on sodium currents of isolated guinea pig and rat ventricular myocytes. J Harbin Med Univ 2006;40:347-50
    • (2006) J Harbin Med Univ , vol.40 , pp. 347-350
    • Gong, D.M.1    Zou, X.L.2    Bai, Y.N.3
  • 72
    • 4544363646 scopus 로고    scopus 로고
    • The ion targets of arrhythmias induced by ouabain and aconitine in guinea pig and rat ventricular myocytes
    • Gong DM, Shan HL. The ion targets of arrhythmias induced by ouabain and aconitine in guinea pig and rat ventricular myocytes. Acta Pharm Sinica 2004;39:328-32
    • (2004) Acta Pharm Sinica , vol.39 , pp. 328-332
    • Gong, D.M.1    Shan, H.L.2
  • 73
    • 84891744233 scopus 로고    scopus 로고
    • Research on toxic effects of aconitine on rat granulose cells
    • Liu QQ, He XJ, Yan GY, et al. Research on toxic effects of aconitine on rat granulose cells. Mod Prev Med 2010;37:299-301
    • (2010) Mod Prev Med , vol.37 , pp. 299-301
    • Liu, Q.Q.1    He, X.J.2    Yan, G.Y.3
  • 74
    • 84891748457 scopus 로고    scopus 로고
    • Toxic effects of aconitine on rat granulose cells
    • Pang LY, Shen F, He XJ, et al. Toxic effects of aconitine on rat granulose cells. West Chin J Pharm Sci 2010;25:278-80
    • (2010) West Chin J Pharm Sci , vol.25 , pp. 278-280
    • Pang, L.Y.1    Shen, F.2    He, X.J.3
  • 75
    • 69749085669 scopus 로고    scopus 로고
    • Effects of a conitine on DNA damage in myocytes of neonatal rats
    • Liu Y, Liang M, Liu Q, et al. Effects of a conitine on DNA damage in myocytes of neonatal rats. Chin J Forensic Med 2009;24:239-41
    • (2009) Chin J Forensic Med , vol.24 , pp. 239-241
    • Liu, Y.1    Liang, M.2    Liu, Q.3
  • 76
    • 84891742972 scopus 로고    scopus 로고
    • Electropharm acological properties of a contine while blocking HERG potassium channels expressed on Xenopuslae visoocytes
    • Li YF, Liao HY. Electropharm acological properties of a contine while blocking HERG potassium channels expressed on Xenopuslae visoocytes. Chin J Card Pacing Electrophysiol 2009;23:528-32
    • (2009) Chin J Card Pacing Electrophysiol , vol.23 , pp. 528-532
    • Li, Y.F.1    Liao, H.Y.2
  • 77
    • 84891746532 scopus 로고    scopus 로고
    • Virulence analysis of aconitine in action of inducing to adarrhythmia and inhibiting heart contraction
    • Pan QW, Wang MY. Virulence analysis of aconitine in action of inducing to adarrhythmia and inhibiting heart contraction. Chin J Mod Appl 2002;19:93-4
    • (2002) Chin J Mod Appl , vol.19 , pp. 93-94
    • Pan, Q.W.1    Wang, M.Y.2
  • 78
    • 72149107957 scopus 로고    scopus 로고
    • Toxicity effects of aconitine on neonatal rat cardiomyocytes
    • Wang YT, Li H.X. Toxicity effects of aconitine on neonatal rat cardiomyocytes. West Chin J Pharm Sci 2007;22:004-6
    • (2007) West Chin J Pharm Sci , vol.22 , pp. 004-6
    • Wang, Y.T.1    Li, H.X.2
  • 79
    • 84891742132 scopus 로고    scopus 로고
    • Study on metabolites of aconitine in rat urine and bile
    • Li WD, Ma C. Study on metabolites of aconitine in rat urine and bile. J Chin Clin Med 2004;5:004-6
    • (2004) J Chin Clin Med , vol.5 , pp. 004-6
    • Li, W.D.1    Ma, C.2
  • 80
    • 85044701982 scopus 로고    scopus 로고
    • Study on metabolites of aconotine in rabbit urine
    • Sun Y, Zhang HG. Study on metabolites of aconotine in rabbit urine. Acta Pharm Sinica 2002;37:781-3
    • (2002) Acta Pharm Sinica , vol.37 , pp. 781-783
    • Sun, Y.1    Zhang, H.G.2
  • 81
    • 79955061439 scopus 로고    scopus 로고
    • Study on the metabolites of aconitine in rabbit blood
    • Zhang HG, Shi XG, Sun Y, et al. Study on the Metabolites of Aconitine in Rabbit Blood. J Jilin Univ (Sci ed) 2006;44:284-6
    • (2006) J Jilin Univ (Sci Ed) , vol.44 , pp. 284-286
    • Zhang, H.G.1    Shi, X.G.2    Sun, Y.3
  • 82
    • 77953592430 scopus 로고    scopus 로고
    • Comparison of metabolites of aconitine in rabbit urine under different routes of administration
    • Liang F, Sui ZG, Yan J, et al. Comparison of metabolites of aconitine in rabbit urine under different routes of administration. J Jilin Univ (Med Ed) 2010;36:443-5
    • (2010) J Jilin Univ (Med Ed) , vol.36 , pp. 443-445
    • Liang, F.1    Sui, Z.G.2    Yan, J.3
  • 83
    • 84891741110 scopus 로고    scopus 로고
    • Determination of aconitine distribution in acute toxic rats by HPLC-MS
    • Wang CH, Wen J, Chen YH, et al. Determination of aconitine distribution in acute toxic rats by HPLC-MS. Chin J Chromatogr 2005;23:88-90
    • (2005) Chin J Chromatogr , vol.23 , pp. 88-90
    • Wang, C.H.1    Wen, J.2    Chen, Y.H.3
  • 84
    • 0033798680 scopus 로고    scopus 로고
    • Progesterone and testosterone modulate the convulsant actions of pentylenetetrazol and strychnine in mice
    • Pesce ME, Ximena A, Diego B, et al. Progesterone and testosterone modulate the convulsant actions of pentylenetetrazol and strychnine in mice. Pharm Toxicol 2000;87:116-19
    • (2000) Pharm Toxicol , vol.87 , pp. 116-119
    • Pesce, M.E.1    Ximena, A.2    Diego, B.3
  • 85
    • 0037341865 scopus 로고    scopus 로고
    • Strychnine-sensitive glycine receptors depress hyperexcitability in rat dentate gyrus
    • Siriporn CC, Mcmahonl LL. Strychnine-sensitive glycine receptors depress hyperexcitability in rat dentate gyrus. J Neurophysiol 2003;89:1339-42
    • (2003) J Neurophysiol , vol.89 , pp. 1339-1342
    • Siriporn, C.C.1    McMahonl, L.L.2
  • 86
    • 0017644692 scopus 로고    scopus 로고
    • Effects of strychnine on the potassium conductance of the frog node of ranvier
    • Shapiro BI. Effects of strychnine on the potassium conductance of the frog node of ranvier. Gen Phys 1997;69:897-914
    • (1997) Gen Phys , vol.69 , pp. 897-914
    • Shapiro, B.I.1
  • 87
    • 84891744581 scopus 로고    scopus 로고
    • The content of strychnine in semen strychni is determined by HPLC and tests its toxicity
    • Wang WL, Shan ZY, Zhang Z, et al. The content of strychnine in semen strychni is determined by HPLC and tests its toxicity. Chin J Basic Med Tradit Chin Med 2004;10:48-50
    • (2004) Chin J Basic Med Tradit Chin Med , vol.10 , pp. 48-50
    • Wang, W.L.1    Shan, Z.Y.2    Zhang, Z.3
  • 88
    • 78349264126 scopus 로고    scopus 로고
    • In vivo research the distribution and Metabolism of strychnine come from semen strychni
    • Zhang Z, Wang Y, Li J. In vivo research the distribution and Metabolism of strychnine come from semen strychni. Liaoning J Tradit Chin Med 1998;25:433-4
    • (1998) Liaoning J Tradit Chin Med , vol.25 , pp. 433-434
    • Zhang, Z.1    Wang, Y.2    Li, J.3
  • 89
    • 3042631090 scopus 로고    scopus 로고
    • Tissue distribution of strychnos nux-vomica alkaloids in rats
    • Cai BC, Xu XY. Tissue distribution of strychnos nux-vomica alkaloids in rats. Chin Pharm Bull 2004;20:421-3
    • (2004) Chin Pharm Bull , vol.20 , pp. 421-423
    • Cai, B.C.1    Xu, X.Y.2
  • 90
    • 0009973802 scopus 로고    scopus 로고
    • Identification of strychnine, brucine and their metabolites in body fluids by liquid chromatography-electrospray ion trap mass spectrometry
    • Guo JF, Chen XY, Zhong DF. Identification of strychnine, brucine and their metabolites in body fluids by liquid chromatography-electrospray ion trap mass spectrometry. Pharm Anal Mag 2001;21:167-9
    • (2001) Pharm Anal Mag , vol.21 , pp. 167-169
    • Guo, J.F.1    Chen, X.Y.2    Zhong, D.F.3
  • 91
    • 0242642287 scopus 로고    scopus 로고
    • Relationship between cardiotonic effects and inhibition on cardiac sarcolemmal Na+, K+-ATPase of strophanthidin at low concentrations
    • Su SW, Wang YL, Li JX, et al. Relationship between cardiotonic effects and inhibition on cardiac sarcolemmal Na+, K+-ATPase of strophanthidin at low concentrations. Acta Pharm Sin 2003;24:1103-7
    • (2003) Acta Pharm Sin , vol.24 , pp. 1103-1107
    • Su, S.W.1    Wang, Y.L.2    Li, J.X.3
  • 92
    • 42549142778 scopus 로고    scopus 로고
    • The effects of strophanthidin on the contractility and calcium transient of a single normal or failure ventricularmyocyte
    • Qi YJ, Li JH, Li SM, et al. The effects of strophanthidin on the contractility and calcium transient of a single normal or failure ventricularmyocyte. Chin Pharml Bull 2008;24:96-100
    • (2008) Chin Pharml Bull , vol.24 , pp. 96-100
    • Qi, Y.J.1    Li, J.H.2    Li, S.M.3
  • 93
    • 67650806350 scopus 로고    scopus 로고
    • Tissue distribution of cinobufagin in vivo in rats
    • Zhang L, Zhang L, Bai X, et al. Tissue distribution of cinobufagin in vivo in rats. Chin Tradit Herb Drugs 2009;40:722-5
    • (2009) Chin Tradit Herb Drugs , vol.40 , pp. 722-725
    • Zhang, L.1    Zhang, L.2    Bai, X.3
  • 94
    • 35949000904 scopus 로고    scopus 로고
    • Effects of divaricoside on intracellular free calcium concentration in single ventricular myocytes of guinea pig
    • Qiu YN, Jian S, Peng QB, et al. Effects of divaricoside on intracellular free calcium concentration in single ventricular myocytes of guinea pig. Chin J pharm toxicol 2007;21:259-66
    • (2007) Chin J Pharm Toxicol , vol.21 , pp. 259-266
    • Qiu, Y.N.1    Jian, S.2    Peng, Q.B.3
  • 95
    • 84891744335 scopus 로고    scopus 로고
    • Inhibitory action of cheiranthoside G on Na+, K+-ATPase
    • Zhang XD, Ji YB, Ma Y, et al. Inhibitory action of cheiranthoside G on Na+, K+-ATPase. Chin Tradit Drug 1999;30:758-9
    • (1999) Chin Tradit Drug , vol.30 , pp. 758-759
    • Zhang, X.D.1    Ji, Y.B.2    Ma, Y.3
  • 96
    • 78049489637 scopus 로고    scopus 로고
    • Effects of triptolide on hypothalamic-pituitary-adrenal axis of rats
    • Zhu JH, Hu YL, Zhang W, et al. Effects of triptolide on hypothalamic-pituitary-adrenal axis of rats. J Forensic Med 2010;26:260-5
    • (2010) J Forensic Med , vol.26 , pp. 260-265
    • Zhu, J.H.1    Hu, Y.L.2    Zhang, W.3
  • 97
    • 84891744861 scopus 로고    scopus 로고
    • Spermatogenic cell apoptosis in juvenile rat caused by multi-glycosides of triptergium wilfordii: A preliminary study
    • Liu LX, Zhang YN, Zhang LL, et al. Spermatogenic cell apoptosis in juvenile rat caused by multi-glycosides of triptergium wilfordii: a preliminary study. Heilongjiang Med Pharm 2010;33:8-9
    • (2010) Heilongjiang Med Pharm , vol.33 , pp. 8-9
    • Liu, L.X.1    Zhang, Y.N.2    Zhang, L.L.3
  • 98
    • 84891737350 scopus 로고    scopus 로고
    • In vitro study of toxicity of triptolide to the testicles of SD rats
    • Zhang JX, Qiu YL, Wang P. In vitro study of toxicity of triptolide to the testicles of SD rats. J Yunnan Agric Univ 2007;22:75-7
    • (2007) J Yunnan Agric Univ , vol.22 , pp. 75-77
    • Zhang, J.X.1    Qiu, Y.L.2    Wang, P.3
  • 99
    • 84891736897 scopus 로고    scopus 로고
    • Effect of single and multiple-dose administration of triptolide on the activities of drug-metabolism enzymes in rat liver microsome
    • Yao JC, Rao J, Zeng L. Effect of single and multiple-dose administration of triptolide on the activities of drug-metabolism enzymes in rat liver microsome. Chin Pharm 2010;21:961-4
    • (2010) Chin Pharm , vol.21 , pp. 961-964
    • Yao, J.C.1    Rao, J.2    Zeng, L.3
  • 100
    • 84891740656 scopus 로고    scopus 로고
    • The subacute renal toxicity of triptolide in wistar rats
    • Shu B, Huang X, Zhang LY, et al. The subacute renal toxicity of triptolide in wistar rats. J Yunnan Univ Tradit Chin Med 2009;32:32-8
    • (2009) J Yunnan Univ Tradit Chin Med , vol.32 , pp. 32-38
    • Shu, B.1    Huang, X.2    Zhang, L.Y.3
  • 101
    • 79952349075 scopus 로고    scopus 로고
    • Myocardial toxicity of triptolide on rats the temporal rhythm effect
    • Guan W, Dai QB, Hu YL, et al. Myocardial toxicity of triptolide on rats the temporal rhythm effect. J Wannan Med Univ 2010;29:18-21
    • (2010) J Wannan Med Univ , vol.29 , pp. 18-21
    • Guan, W.1    Dai, Q.B.2    Hu, Y.L.3
  • 102
    • 77950546600 scopus 로고    scopus 로고
    • Studies on rat intestinal absorption of triptolidein situ
    • Xue J, Jia XB, Tan XB, et al. Studies on rat intestinal absorption of triptolidein situ. Chin Tradit Herb Drugs 2010;41:86-9
    • (2010) Chin Tradit Herb Drugs , vol.41 , pp. 86-89
    • Xue, J.1    Jia, X.B.2    Tan, X.B.3
  • 103
    • 84891748505 scopus 로고    scopus 로고
    • Metabolism and enzyme kinetics of triptolide in rat liver microsomes
    • Yao JC, Rao J, He LG, et al. Metabolism and enzyme kinetics of triptolide in rat liver microsomes. Chin Pharm 2010;21:577-9
    • (2010) Chin Pharm , vol.21 , pp. 577-579
    • Yao, J.C.1    Rao, J.2    He, L.G.3


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