SCOPUS 정보 검색 플랫폼

Volumn 1, Issue 10, 2014, Pages 1166-1171

Function through bio-inspired, synthesis-informed design: Step-economical syntheses of designed kinase inhibitors

(7) Wender, Paul A a Axtman, Alison D a Golden, Jennifer E a Kee, Jung Min a Sirois, Lauren E a Quiroz, Ryan V a Stevens, Matthew C a

a STANFORD UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; ENZYME INHIBITION; SCAFFOLDS (BIOLOGY);

CARDIO-VASCULAR DISEASE; CELLULAR FUNCTION; KINASE INHIBITORS; NANOMOLAR INHIBITORS; NATURAL PRODUCTS; NEUROLOGICAL DISORDERS; STAUROSPORINES; [4 + 2] CYCLOADDITION;

BIOSYNTHESIS;

EID: 84925450037 PISSN: 20524110 EISSN: 20524129 Source Type: Journal
DOI: 10.1039/c4qo00228h Document Type: Article

Times cited : (6)

References (45)

1
- 0035413617
- A. J. Bridges Chem. Rev. 2001 101 2541
- (2001) Chem. Rev. , vol.101 , pp. 2541
- Bridges, A.J.¹

2
- 67650457580
- D. Tanramluk A. Schreyer W. R. Pitt T. L. Blundell Chem. Biol. Drug Des. 2009 74 16
- (2009) Chem. Biol. Drug Des. , vol.74 , pp. 16
- Tanramluk, D.¹ Schreyer, A.² Pitt, W.R.³ Blundell, T.L.⁴

3
- 84874301754
- Q. Liu Y. Sabnis Z. Zhao T. Zhang S. J. Buhrlage L. H. Jones N. S. Gray Chem. Biol. 2013 20 146
- (2013) Chem. Biol. , vol.20 , pp. 146
- Liu, Q.¹ Sabnis, Y.² Zhao, Z.³ Zhang, T.⁴ Buhrlage, S.J.⁵ Jones, L.H.⁶ Gray, N.S.⁷

4
- 84903217674
- S. Regot J. J. Hughey B. T. Bajar S. Carrasco M. W. Covert Cell 2014 157 1724
- (2014) Cell , vol.157 , pp. 1724
- Regot, S.¹ Hughey, J.J.² Bajar, B.T.³ Carrasco, S.⁴ Covert, M.W.⁵

5
- 84872515516
- P. Cohen D. R. Alessi ACS Chem. Biol. 2013 8 96
- (2013) ACS Chem. Biol. , vol.8 , pp. 96
- Cohen, P.¹ Alessi, D.R.²

6
- 57749188299
- J. Zhang P. L. Yang N. S. Gray Nat. Rev. Cancer 2009 9 28
- (2009) Nat. Rev. Cancer , vol.9 , pp. 28
- Zhang, J.¹ Yang, P.L.² Gray, N.S.³

7
- 84939510517
- AIDS Research Alliance
- AIDS Research Alliance, http://aidsresearch.org/cure-research/

8
- 84880351418
- E. J. Beans D. Fournogerakis C. Gauntlett L. V. Heumann R. Kramer M. D. Marsden D. Murray T.-W. Chun J. A. Zack P. A. Wender Proc. Natl. Acad. Sci. U. S. A. 2013 110 11698
- (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 11698
- Beans, E.J.¹ Fournogerakis, D.² Gauntlett, C.³ Heumann, L.V.⁴ Kramer, R.⁵ Marsden, M.D.⁶ Murray, D.⁷ Chun, T.-W.⁸ Zack, J.A.⁹ Wender, P.A.¹⁰

9
- 84939478949
- Clinical trial:. For work from our group and others see
- Clinical trial: http://clinicaltrials.gov/show/NCT00606164

10
- 64449084409
- T. K. Khan T. J. Nelson V. A. Verma P. A. Wender D. L. Alkon Neurobiol. Dis. 2009 34 332
- (2009) Neurobiol. Dis. , vol.34 , pp. 332
- Khan, T.K.¹ Nelson, T.J.² Verma, V.A.³ Wender, P.A.⁴ Alkon, D.L.⁵

11
- 78651483724
- J. Hongpaisan M.-K. Sun D. L. Alkon J. Neurosci. 2011 31 630
- (2011) J. Neurosci. , vol.31 , pp. 630
- Hongpaisan, J.¹ Sun, M.-K.² Alkon, D.L.³

12
- 84870772239
- D. Mochly-Rosen K. Das K. V. Grimes Nat. Rev. Drug Discovery 2012 11 937
- (2012) Nat. Rev. Drug Discovery , vol.11 , pp. 937
- Mochly-Rosen, D.¹ Das, K.² Grimes, K.V.³

13
- 84899065920
- A. Takashima B. English Z. Chen J. Cao R. Cui R. M. Williams D. V. Faller ACS Chem. Biol. 2014 9 1003
- (2014) ACS Chem. Biol. , vol.9 , pp. 1003
- Takashima, A.¹ English, B.² Chen, Z.³ Cao, J.⁴ Cui, R.⁵ Williams, R.M.⁶ Faller, D.V.⁷

14
- 84920848441
- ASAP
- Y. Hu N. Furtmann J. Bajorath J. Med. Chem. 2014 10.1021/jm5008159, ASAP
- (2014) J. Med. Chem.
- Hu, Y.¹ Furtmann, N.² Bajorath, J.³

15
- 33846899405
- J. J.-L. Liao J. Med. Chem. 2007 50 409
- (2007) J. Med. Chem. , vol.50 , pp. 409
- Liao, J.J.-L.¹

16
- 8944246315
- M. R. Jirousek et al. J. Med. Chem. 1996 39 2664
- (1996) J. Med. Chem. , vol.39 , pp. 2664
- Jirousek, M.R.¹

17
- 0038394537
- M. M. Faul J. R. Gillig M. R. Jirousek L. M. Ballas T. Schotten A. Kahl M. Mohr Bioorg. Med. Chem. Lett. 2003 13 1857
- (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 1857
- Faul, M.M.¹ Gillig, J.R.² Jirousek, M.R.³ Ballas, L.M.⁴ Schotten, T.⁵ Kahl, A.⁶ Mohr, M.⁷

18
- 84889805348
- M. S. Lopez J. W. Choy U. Peters M. L. Sos D. O. Morgan K. M. Shokat J. Am. Chem. Soc. 2013 135 18153
- (2013) J. Am. Chem. Soc. , vol.135 , pp. 18153
- Lopez, M.S.¹ Choy, J.W.² Peters, U.³ Sos, M.L.⁴ Morgan, D.O.⁵ Shokat, K.M.⁶

19
- 84890138834
- S. Ichikawa N. Tatebayashi A. Matsuda J. Org. Chem. 2013 78 12065
- (2013) J. Org. Chem. , vol.78 , pp. 12065
- Ichikawa, S.¹ Tatebayashi, N.² Matsuda, A.³

20
- 84866842026
- B. A. DeChristopher B. A. Loy M. D. Marsden A. J. Schrier J. A. Zack P. A. Wender Nat. Chem. 2012 4 705
- (2012) Nat. Chem. , vol.4 , pp. 705
- DeChristopher, B.A.¹ Loy, B.A.² Marsden, M.D.³ Schrier, A.J.⁴ Zack, J.A.⁵ Wender, P.A.⁶

21
- 84918821254
- ed. S. Hanessian, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany
- P. A. Wender, A. C. Axtman, B. A. Loy, K. E. Near and D. Staveness, in Natural Products in Medicinal Chemistry, ed., S. Hanessian, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2014 10.1002/9783527676545.ch14
- (2014) Natural Products in Medicinal Chemistry
- Wender, P.A.¹ Axtman, A.C.² Loy, B.A.³ Near, K.E.⁴ Staveness, D.⁵

22
- 38949138457
- P. A. Wender V. V. Verma T. J. Paxton T. H. Pillow Acc. Chem. Res. 2008 41 40
- (2008) Acc. Chem. Res. , vol.41 , pp. 40
- Wender, P.A.¹ Verma, V.V.² Paxton, T.J.³ Pillow, T.H.⁴

23
- 0017395981
- S. Omura Y. Iwai A. Hirano A. Nakagawa J. Awaya H. Tsuchiya Y. Takahashi R. Masuma J. Antibiot. 1977 30 275
- (1977) J. Antibiot. , vol.30 , pp. 275
- Omura, S.¹ Iwai, Y.² Hirano, A.³ Nakagawa, A.⁴ Awaya, J.⁵ Tsuchiya, H.⁶ Takahashi, Y.⁷ Masuma, R.⁸

24
- 38049018155
- M. W. Karaman et al. Nat. Biotechnol. 2008 26 127
- (2008) Nat. Biotechnol. , vol.26 , pp. 127
- Karaman, M.W.¹

25
- 0000314933
- J. T. Link S. Raghavan M. Gallant S. J. Danishefsky T. C. Chou L. M. Ballas J. Am. Chem. Soc. 1996 118 2825
- (1996) J. Am. Chem. Soc. , vol.118 , pp. 2825
- Link, J.T.¹ Raghavan, S.² Gallant, M.³ Danishefsky, S.J.⁴ Chou, T.C.⁵ Ballas, L.M.⁶

26
- 0029841520
- J. L. Wood B. M. Stoltz S. N. Goodman J. Am. Chem. Soc. 1996 118 10656
- (1996) J. Am. Chem. Soc. , vol.118 , pp. 10656
- Wood, J.L.¹ Stoltz, B.M.² Goodman, S.N.³

27
- 77950137429
- O. Gani R. A. Engh Nat. Prod. Rep. 2010 27 489
- (2010) Nat. Prod. Rep. , vol.27 , pp. 489
- Gani, O.¹ Engh, R.A.²

28
- 67650527061
- P. A. Wender B. L. Miller Nature 2009 460 197
- (2009) Nature , vol.460 , pp. 197
- Wender, P.A.¹ Miller, B.L.²

29
- 84896132919
- P. A. Wender Nat. Prod. Rep. 2014 31 433
- (2014) Nat. Prod. Rep. , vol.31 , pp. 433
- Wender, P.A.¹

30
- 0028956752
- P. A. Wender H. Takahashi B. Witulski J. Am. Chem. Soc. 1995 117 4720
- (1995) J. Am. Chem. Soc. , vol.117 , pp. 4720
- Wender, P.A.¹ Takahashi, H.² Witulski, B.³

31
- 0032576188
- P. A. Wender H. Rieck M. Fuji J. Am. Chem. Soc. 1998 120 10976
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 10976
- Wender, P.A.¹ Rieck, H.² Fuji, M.³

32
- 0037011303
- P. A. Wender T. J. Williams Angew. Chem., Int. Ed. 2002 41 4550
- (2002) Angew. Chem., Int. Ed. , vol.41 , pp. 4550
- Wender, P.A.¹ Williams, T.J.²

33
- 77950192886
- P. A. Wender L. E. Sirois R. T. Stemmler T. J. Williams Org. Lett. 2010 12 1604
- (2010) Org. Lett. , vol.12 , pp. 1604
- Wender, P.A.¹ Sirois, L.E.² Stemmler, R.T.³ Williams, T.J.⁴

34
- 84899101464
- P. A. Wender D. N. Fournogerakis M. S. Jeffreys R. V. Quiroz F. Inagaki M. Pfaffenbach Nat. Chem. 2014 6 448
- (2014) Nat. Chem. , vol.6 , pp. 448
- Wender, P.A.¹ Fournogerakis, D.N.² Jeffreys, M.S.³ Quiroz, R.V.⁴ Inagaki, F.⁵ Pfaffenbach, M.⁶

35
- 0035886047
- P. A. Wender G. G. Gamber M. J. C. Scanio Angew. Chem., Int. Ed. 2001 40 3895
- (2001) Angew. Chem., Int. Ed. , vol.40 , pp. 3895
- Wender, P.A.¹ Gamber, G.G.² Scanio, M.J.C.³

36
- 0026533930
- P. D. Davis C. H. Hill G. Lawton J. S. Nixon S. E. Wilkinson S. A. Hurst E. Keech S. E. Turner J. Med. Chem. 1992 35 177
- (1992) J. Med. Chem. , vol.35 , pp. 177
- Davis, P.D.¹ Hill, C.H.² Lawton, G.³ Nixon, J.S.⁴ Wilkinson, S.E.⁵ Hurst, S.A.⁶ Keech, E.⁷ Turner, S.E.⁸

37
- 0000771565
- J. Bergman L. Venemalm J. Org. Chem. 1992 57 2495
- (1992) J. Org. Chem. , vol.57 , pp. 2495
- Bergman, J.¹ Venemalm, L.²

38
- 0034050746
- H. Tokuyama Y. Kaburagi X. Chen T. Fukuyama Synthesis 2000 429
- (2000) Synthesis , pp. 429
- Tokuyama, H.¹ Kaburagi, Y.² Chen, X.³ Fukuyama, T.⁴

39
- 0025127244
- P. D. Davis R. A. Bit Tetrahedron Lett. 1990 31 5201
- (1990) Tetrahedron Lett. , vol.31 , pp. 5201
- Davis, P.D.¹ Bit, R.A.²

40
- 0020491337
- U. Kikkawa Y. Takai R. Minakuchi S. Inohara Y. Nishizuka J. Biol. Chem. 1982 25 13341
- (1982) J. Biol. Chem. , vol.25 , pp. 13341
- Kikkawa, U.¹ Takai, Y.² Minakuchi, R.³ Inohara, S.⁴ Nishizuka, Y.⁵

41
- 0024828113
- P. D. Davis C. H. Hill E. Keech G. Lawton J. S. Nixon A. D. Sedgwik J. Wadworth D. Westmacott S. E. Wilkinson FEBS Lett. 1989 259 61
- (1989) FEBS Lett. , vol.259 , pp. 61
- Davis, P.D.¹ Hill, C.H.² Keech, E.³ Lawton, G.⁴ Nixon, J.S.⁵ Sedgwik, A.D.⁶ Wadworth, J.⁷ Westmacott, D.⁸ Wilkinson, S.E.⁹

42
- 0037010783
- R. J. Rahaim Jr. R. E. Maleczka Jr. Tetrahedron Lett. 2002 43 8823
- (2002) Tetrahedron Lett. , vol.43 , pp. 8823
- Rahaim, Jr.R.J.¹ Maleczka, Jr.R.E.²

43
- 0000207314
- P. A. A. Klusener W. Kulik L. Brandsma J. Org. Chem. 1987 52 5261
- (1987) J. Org. Chem. , vol.52 , pp. 5261
- Klusener, P.A.A.¹ Kulik, W.² Brandsma, L.³

44
- 0022491419
- T. Tamaoki H. Nomoto I. Takahashi Y. Kato M. Morimoto F. Tomita Biochem. Biophys. Res. Commun. 1986 135 397
- (1986) Biochem. Biophys. Res. Commun. , vol.135 , pp. 397
- Tamaoki, T.¹ Nomoto, H.² Takahashi, I.³ Kato, Y.⁴ Morimoto, M.⁵ Tomita, F.⁶

45
- 84939559019
- Schrödinger, LLC, New York, NY
- Maestro GUI version 8.0, Schrödinger, LLC, New York, NY, 2007
- (2007) Maestro GUI Version 8.0

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.