Downregulation of NIT2 inhibits colon cancer cell proliferation and induces cell cycle arrest through the caspase-3 and PARP pathways

International Journal of Molecular Medicine

Volumn 35, Issue 5, 2015, Pages 1317-1322

  Zheng, Bo'an ^a   Chai, Rui ^a   Yu, Xiaojun ^a  

^a ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Colon cancer; NIT2; Proliferation; RNA interference

Indexed keywords

CASPASE 3; COMPLEMENTARY DNA; LENTIVIRUS VECTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRILASE; NITRILASE 2; RNA; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; HYDROLASE; MESSENGER RNA;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL PROLIFERATION; CELL VIABILITY ASSAY; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; GROWTH INHIBITION; HCT116 CELL LINE; HEK293 CELL LINE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LENTIVIRUS INFECTION; MOLECULARLY TARGETED THERAPY; MTT ASSAY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; CELL CYCLE CHECKPOINT; COLON TUMOR; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; LENTIVIRINAE; METABOLISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMINOHYDROLASES; CASPASE 3; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VECTORS; HUMANS; LENTIVIRUS; POLY(ADP-RIBOSE) POLYMERASES; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84925448688     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2125     Document Type: Article

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