-
1
-
-
84981860375
-
Role of chance observations in chemotherapy: Vinca rosea
-
Noble, R. L.; Beer, C. T.; Cutts, J. H. Role of chance observations in chemotherapy: Vinca rosea Ann. N.Y. Acad. Sci. 1958, 76, 882-894
-
(1958)
Ann. N.Y. Acad. Sci.
, vol.76
, pp. 882-894
-
-
Noble, R.L.1
Beer, C.T.2
Cutts, J.H.3
-
2
-
-
26444618252
-
Catharanthus roseus (vinca rosea): Importance and value of a chance observation
-
Noble, R. L. Catharanthus roseus (vinca rosea): Importance and value of a chance observation Lloydia 1964, 27, 280-281
-
(1964)
Lloydia
, vol.27
, pp. 280-281
-
-
Noble, R.L.1
-
3
-
-
70449286540
-
Alkaloids of Vinca rosea Linn. (Catharanthus roseus G. Don.). V. Preparation and characterization of alkaloids
-
Svoboda, G. H.; Nuess, N.; Gorman, M. Alkaloids of Vinca rosea Linn. (Catharanthus roseus G. Don.). V. Preparation and characterization of alkaloids J. Am. Pharm. Assoc. Sci. Ed. 1959, 48, 659-666
-
(1959)
J. Am. Pharm. Assoc. Sci. Ed.
, vol.48
, pp. 659-666
-
-
Svoboda, G.H.1
Nuess, N.2
Gorman, M.3
-
4
-
-
77957065406
-
Therapeutic use of bisindole alkaloids from catharanthus
-
Brossi, A. Suffness, M., Eds.; Academic: San Diego, CA
-
Neuss, N.; Neuss, M. N. Therapeutic use of bisindole alkaloids from catharanthus. In The Alkaloids; Brossi, A.; Suffness, M., Eds.; Academic: San Diego, CA, 1990; Vol. 37, pp 229-240.
-
(1990)
The Alkaloids
, vol.37
, pp. 229-240
-
-
Neuss, N.1
Neuss, M.N.2
-
5
-
-
77957080344
-
Medicinal chemistry of bisindole alkaloids from Catharanthus
-
Brossi, A. Suffness, M., Eds.; Academic: San Diego, CA
-
Pearce, H. L. Medicinal chemistry of bisindole alkaloids from Catharanthus. In The Alkaloids; Brossi, A.; Suffness, M., Eds.; Academic: San Diego, CA, 1990; Vol. 37, pp 145-204.
-
(1990)
The Alkaloids
, vol.37
, pp. 145-204
-
-
Pearce, H.L.1
-
6
-
-
77957095647
-
Syntheses of vinblastine-type alkaloids
-
Brossi, A. Suffness, M., Eds.; Academic: San Diego, CA
-
Kuehne, M. E.; Marko, I. Syntheses of vinblastine-type alkaloids. In The Alkaloids; Brossi, A.; Suffness, M., Eds.; Academic: San Diego, CA, 1990; Vol. 37, pp 77-132.
-
(1990)
The Alkaloids
, vol.37
, pp. 77-132
-
-
Kuehne, M.E.1
Marko, I.2
-
7
-
-
0034741810
-
Modifications in the "upper" velbenamine part of the Vinca alkaloids have major implications for tubulin interacting activities
-
Fahy, J. Modifications in the "upper" velbenamine part of the Vinca alkaloids have major implications for tubulin interacting activities Curr. Pharm. Des. 2001, 7, 1181-1197
-
(2001)
Curr. Pharm. Des.
, vol.7
, pp. 1181-1197
-
-
Fahy, J.1
-
8
-
-
0019130682
-
Synthesis of the antitumor dimeric indole alkaloids from catharanthus species (vinblastine group)
-
Potier, P. Synthesis of the antitumor dimeric indole alkaloids from catharanthus species (vinblastine group) J. Nat. Prod. 1980, 43, 72-86
-
(1980)
J. Nat. Prod.
, vol.43
, pp. 72-86
-
-
Potier, P.1
-
9
-
-
0000018728
-
Plant cell culture combined with chemistry: A powerful route to complex natural products
-
Kutney, J. P. Plant cell culture combined with chemistry: a powerful route to complex natural products Acc. Chem. Res. 1993, 26, 559-566
-
(1993)
Acc. Chem. Res.
, vol.26
, pp. 559-566
-
-
Kutney, J.P.1
-
10
-
-
0017172977
-
Application of a modification of the Polonovski reaction to the synthesis of vinblastine-type alkaloids
-
Langlois, N.; Gueritte, F.; Langlois, Y.; Potier, P. Application of a modification of the Polonovski reaction to the synthesis of vinblastine-type alkaloids J. Am. Chem. Soc. 1976, 98, 7017-7024
-
(1976)
J. Am. Chem. Soc.
, vol.98
, pp. 7017-7024
-
-
Langlois, N.1
Gueritte, F.2
Langlois, Y.3
Potier, P.4
-
11
-
-
0017085389
-
Total synthesis of indole and dihydroindole alkaloids. IX. Studies on the synthesis of bisindole alkaloids in the vinblastine-vincristine series. The biogenetic approach
-
Kutney, J. P.; Hibino, T.; Jahngen, E.; Okutani, T.; Ratcliffe, A. H.; Treasurywala, A. M.; Wunderly, S. Total synthesis of indole and dihydroindole alkaloids. IX. Studies on the synthesis of bisindole alkaloids in the vinblastine-vincristine series. The biogenetic approach Helv. Chim. Acta 1976, 59, 2858-2882
-
(1976)
Helv. Chim. Acta
, vol.59
, pp. 2858-2882
-
-
Kutney, J.P.1
Hibino, T.2
Jahngen, E.3
Okutani, T.4
Ratcliffe, A.H.5
Treasurywala, A.M.6
Wunderly, S.7
-
12
-
-
0025980121
-
Enantioselective syntheses of vinblastine, leurosidine, vincovaline and 20′-epi-vincovaline
-
Kuehne, M. E.; Matson, P. A.; Bornmann, W. G. Enantioselective syntheses of vinblastine, leurosidine, vincovaline and 20′-epi-vincovaline J. Org. Chem. 1991, 56, 513-528
-
(1991)
J. Org. Chem.
, vol.56
, pp. 513-528
-
-
Kuehne, M.E.1
Matson, P.A.2
Bornmann, W.G.3
-
13
-
-
0026550708
-
A common intermediate providing syntheses of ψ-tabersonine, coronaridine, iboxyphylline, ibophyllidine, vinamidine, and vinblastine
-
Bornmann, W. G.; Kuehne, M. E. A common intermediate providing syntheses of ψ-tabersonine, coronaridine, iboxyphylline, ibophyllidine, vinamidine, and vinblastine J. Org. Chem. 1992, 57, 1752-1760
-
(1992)
J. Org. Chem.
, vol.57
, pp. 1752-1760
-
-
Bornmann, W.G.1
Kuehne, M.E.2
-
14
-
-
0037070544
-
Stereocontrolled total synthesis of (+)-vinblastine
-
Yokoshima, S.; Ueda, T.; Kobayashi, S.; Sato, A.; Kuboyama, T.; Tokuyama, H.; Fukuyama, T. Stereocontrolled total synthesis of (+)-vinblastine J. Am. Chem. Soc. 2002, 124, 2137-2139
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 2137-2139
-
-
Yokoshima, S.1
Ueda, T.2
Kobayashi, S.3
Sato, A.4
Kuboyama, T.5
Tokuyama, H.6
Fukuyama, T.7
-
15
-
-
4344629173
-
Stereocontrolled total synthesis of (+)-vincristine
-
Kuboyama, T.; Yokoshima, S.; Tokuyama, H.; Fukuyama, T. Stereocontrolled total synthesis of (+)-vincristine Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 11966-11970
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 11966-11970
-
-
Kuboyama, T.1
Yokoshima, S.2
Tokuyama, H.3
Fukuyama, T.4
-
16
-
-
0025010161
-
Synthesis of the antitumor bisindole alkaloid vinblastine: Diastereoselectivity and solvent effect on the stereochemistry of the crucial C-15-C-18′ bond
-
Magnus, P.; Stamford, A.; Ladlow, M. Synthesis of the antitumor bisindole alkaloid vinblastine: diastereoselectivity and solvent effect on the stereochemistry of the crucial C-15-C-18′ bond J. Am. Chem. Soc. 1990, 112, 8210-8212
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 8210-8212
-
-
Magnus, P.1
Stamford, A.2
Ladlow, M.3
-
17
-
-
67949110944
-
Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues
-
Ishikawa, H.; Colby, D. A.; Seto, S.; Va, P.; Tam, A.; Kakei, H.; Rayl, T. J.; Hwang, I.; Boger, D. L. Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues J. Am. Chem. Soc. 2009, 131, 4904-4916
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 4904-4916
-
-
Ishikawa, H.1
Colby, D.A.2
Seto, S.3
Va, P.4
Tam, A.5
Kakei, H.6
Rayl, T.J.7
Hwang, I.8
Boger, D.L.9
-
18
-
-
33747600674
-
Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids
-
Ishikawa, H.; Elliott, G. I.; Velcicky, J.; Choi, Y.; Boger, D. L. Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids J. Am. Chem. Soc. 2006, 128, 10596-10612
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 10596-10612
-
-
Ishikawa, H.1
Elliott, G.I.2
Velcicky, J.3
Choi, Y.4
Boger, D.L.5
-
19
-
-
26444541805
-
Total synthesis of (-)- and ent -(+)-vindoline
-
Choi, Y.; Ishikawa, H.; Velcicky, J.; Elliott, G. I.; Miller, M. M.; Boger, D. L. Total synthesis of (-)- and ent -(+)-vindoline Org. Lett. 2005, 7, 4539-4542
-
(2005)
Org. Lett.
, vol.7
, pp. 4539-4542
-
-
Choi, Y.1
Ishikawa, H.2
Velcicky, J.3
Elliott, G.I.4
Miller, M.M.5
Boger, D.L.6
-
20
-
-
14844339765
-
Total synthesis of natural (-)- and ent-(+)-4-desacetoxy-6,7-dihydrovindorosine and natural and ent-minovine: Oxadiazole tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reaction
-
Yuan, Z.; Ishikawa, H.; Boger, D. L. Total synthesis of natural (-)- and ent -(+)-4-desacetoxy-6,7-dihydrovindorosine and natural and ent -minovine: oxadiazole tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reaction Org. Lett. 2005, 7, 741-744
-
(2005)
Org. Lett.
, vol.7
, pp. 741-744
-
-
Yuan, Z.1
Ishikawa, H.2
Boger, D.L.3
-
21
-
-
31044433462
-
Total synthesis of (-)- and ent-(+)-vindorosine: Tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reaction of 1,3,4-oxadiazoles
-
Elliott, G. I.; Velcicky, J.; Ishikawa, H.; Li, Y.; Boger, D. L. Total synthesis of (-)- and ent-(+)-vindorosine: tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reaction of 1,3,4-oxadiazoles Angew. Chem., Int. Ed. 2006, 45, 620-622
-
(2006)
Angew. Chem., Int. Ed.
, vol.45
, pp. 620-622
-
-
Elliott, G.I.1
Velcicky, J.2
Ishikawa, H.3
Li, Y.4
Boger, D.L.5
-
22
-
-
34547830832
-
Total synthesis of natural (-)- and ent-(+)-4-desacetoxy-5-desethylvindoline
-
Ishikawa, H.; Boger, D. L. Total synthesis of natural (-)- and ent-(+)-4-desacetoxy-5-desethylvindoline Heterocycles 2007, 72, 95-102
-
(2007)
Heterocycles
, vol.72
, pp. 95-102
-
-
Ishikawa, H.1
Boger, D.L.2
-
23
-
-
33747610224
-
Intramolecular Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles
-
Elliott, G. I.; Fuchs, J. R.; Blagg, B. S. J.; Ishikawa, H.; Tao, H.; Yuan, Z.; Boger, D. L. Intramolecular Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles J. Am. Chem. Soc. 2006, 128, 10589-10595
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 10589-10595
-
-
Elliott, G.I.1
Fuchs, J.R.2
Blagg, B.S.J.3
Ishikawa, H.4
Tao, H.5
Yuan, Z.6
Boger, D.L.7
-
24
-
-
0037174410
-
Intramolecular Diels-Alder and tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reactions of 1,3,4-oxadiazoles
-
Wilkie, G. D.; Elliott, G. I.; Blagg, B. S. J.; Wolkenberg, S. E.; Soenen, D. B.; Miller, M. M.; Pollack, S.; Boger, D. L. Intramolecular Diels-Alder and tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reactions of 1,3,4-oxadiazoles J. Am. Chem. Soc. 2002, 124, 11292-11294
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 11292-11294
-
-
Wilkie, G.D.1
Elliott, G.I.2
Blagg, B.S.J.3
Wolkenberg, S.E.4
Soenen, D.B.5
Miller, M.M.6
Pollack, S.7
Boger, D.L.8
-
25
-
-
45449097286
-
Diels-Alder reactions of azadienes
-
Boger, D. L. Diels-Alder reactions of azadienes Tetrahedron 1983, 39, 2869-2939
-
(1983)
Tetrahedron
, vol.39
, pp. 2869-2939
-
-
Boger, D.L.1
-
26
-
-
33845376451
-
Diels-Alder reactions of heterocyclic azadienes
-
Boger, D. L. Diels-Alder reactions of heterocyclic azadienes Chem. Rev. 1986, 86, 781-793
-
(1986)
Chem. Rev.
, vol.86
, pp. 781-793
-
-
Boger, D.L.1
-
27
-
-
0023835716
-
Production of 3′,4′-anhydrovinblastine: A unique chemical synthesis
-
Vukovic, J.; Goodbody, A. E.; Kutney, J. P.; Misawa, M. Production of 3′,4′-anhydrovinblastine: a unique chemical synthesis Tetrahedron 1988, 44, 325-331
-
(1988)
Tetrahedron
, vol.44
, pp. 325-331
-
-
Vukovic, J.1
Goodbody, A.E.2
Kutney, J.P.3
Misawa, M.4
-
28
-
-
40149110727
-
Direct coupling of catharanthine and vindoline to provide vinblastine: Total synthesis of (+)- and ent-(-)-vinblastine
-
Ishikawa, H.; Colby, D. A.; Boger, D. L. Direct coupling of catharanthine and vindoline to provide vinblastine: total synthesis of (+)- and ent-(-)-vinblastine J. Am. Chem. Soc. 2008, 130, 420-421
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 420-421
-
-
Ishikawa, H.1
Colby, D.A.2
Boger, D.L.3
-
29
-
-
77957154690
-
Asymmetric total synthesis of vindorosine, vindoline, and key vinblastine analogues
-
Sasaki, Y.; Kato, D.; Boger, D. L. Asymmetric total synthesis of vindorosine, vindoline, and key vinblastine analogues J. Am. Chem. Soc. 2010, 132, 13533-13544
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 13533-13544
-
-
Sasaki, Y.1
Kato, D.2
Boger, D.L.3
-
30
-
-
77949853491
-
Asymmetric total synthesis of vindoline
-
Kato, D.; Sasaki, Y.; Boger, D. L. Asymmetric total synthesis of vindoline J. Am. Chem. Soc. 2010, 132, 3685-3687
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 3685-3687
-
-
Kato, D.1
Sasaki, Y.2
Boger, D.L.3
-
31
-
-
0142010038
-
Syntheses and biological evaluation of vinblastine congeners
-
Kuehne, M. E.; Bornmann, W. G.; Marko, I.; Qin, Y.; Le Boulluec, K. L.; Frasier, D. A.; Xu, F.; Malamba, T.; Ensinger, C. L.; Borman, L. S.; Huot, A. E.; Exon, C.; Bizzarro, F. T.; Cheung, J. B.; Bane, S. L. Syntheses and biological evaluation of vinblastine congeners Org. Biomol. Chem. 2003, 1, 2120-2136
-
(2003)
Org. Biomol. Chem.
, vol.1
, pp. 2120-2136
-
-
Kuehne, M.E.1
Bornmann, W.G.2
Marko, I.3
Qin, Y.4
Le Boulluec, K.L.5
Frasier, D.A.6
Xu, F.7
Malamba, T.8
Ensinger, C.L.9
Borman, L.S.10
Huot, A.E.11
Exon, C.12
Bizzarro, F.T.13
Cheung, J.B.14
Bane, S.L.15
-
32
-
-
36348942481
-
Synthesis of (+)-vinblastine and its analogues
-
Miyazaki, T.; Yokoshima, S.; Simizu, S.; Osada, H.; Tokuyama, H.; Fukuyama, T. Synthesis of (+)-vinblastine and its analogues Org. Lett. 2007, 9, 4737-4740
-
(2007)
Org. Lett.
, vol.9
, pp. 4737-4740
-
-
Miyazaki, T.1
Yokoshima, S.2
Simizu, S.3
Osada, H.4
Tokuyama, H.5
Fukuyama, T.6
-
33
-
-
59849129251
-
Synthesis and SAR of vinca alkaloid analogues
-
Voss, M. E.; Ralph, J. M.; Xie, D.; Manning, D. D.; Chen, X.; Frank, A. J.; Leyhane, A. J.; Liu, L.; Stevens, J. M.; Budde, C.; Surman, M. D.; Friedrich, T.; Peace, D.; Scott, I. L.; Wolf, M.; Johnson, R. Synthesis and SAR of vinca alkaloid analogues Bioorg. Med. Chem. Lett. 2009, 19, 1245-1249
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 1245-1249
-
-
Voss, M.E.1
Ralph, J.M.2
Xie, D.3
Manning, D.D.4
Chen, X.5
Frank, A.J.6
Leyhane, A.J.7
Liu, L.8
Stevens, J.M.9
Budde, C.10
Surman, M.D.11
Friedrich, T.12
Peace, D.13
Scott, I.L.14
Wolf, M.15
Johnson, R.16
-
34
-
-
84881472260
-
Synthesis and biological evaluation of a new series of highly functionalized 7′-homo-anhydrovinblastine derivatives
-
Gherbovet, O.; Coderch, C.; Alvarez, M. C. G.; Bignon, J.; Thoret, S.; Martin, M.-T.; Guéritte, F.; Gago, F.; Roussi, F. Synthesis and biological evaluation of a new series of highly functionalized 7′-homo-anhydrovinblastine derivatives J. Med. Chem. 2013, 56, 6088-6100
-
(2013)
J. Med. Chem.
, vol.56
, pp. 6088-6100
-
-
Gherbovet, O.1
Coderch, C.2
Alvarez, M.C.G.3
Bignon, J.4
Thoret, S.5
Martin, M.-T.6
Guéritte, F.7
Gago, F.8
Roussi, F.9
-
35
-
-
77953636730
-
Total synthesis and evaluation of a key series of C5-substituted vinblastine derivatives
-
Va, P.; Campbell, E. L.; Robertson, W. M.; Boger, D. L. Total synthesis and evaluation of a key series of C5-substituted vinblastine derivatives J. Am. Chem. Soc. 2010, 132, 8489-8495
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 8489-8495
-
-
Va, P.1
Campbell, E.L.2
Robertson, W.M.3
Boger, D.L.4
-
36
-
-
84872818405
-
Total synthesis and evaluation of vinblastine analogues containing systematic deep-seated modifications in the vindoline subunit ring system: Core redesign
-
Schleicher, K. D.; Sasaki, Y.; Tam, A.; Kato, D.; Duncan, K. K.; Boger, D. L. Total synthesis and evaluation of vinblastine analogues containing systematic deep-seated modifications in the vindoline subunit ring system: core redesign J. Med. Chem. 2013, 56, 483-495
-
(2013)
J. Med. Chem.
, vol.56
, pp. 483-495
-
-
Schleicher, K.D.1
Sasaki, Y.2
Tam, A.3
Kato, D.4
Duncan, K.K.5
Boger, D.L.6
-
37
-
-
84858665556
-
4-mediated additions to unactivated alkenes: Synthesis of novel 20′-vinblastine analogues
-
4-mediated additions to unactivated alkenes: synthesis of novel 20′-vinblastine analogues Org. Lett. 2012, 14, 1428-1431
-
(2012)
Org. Lett.
, vol.14
, pp. 1428-1431
-
-
Leggans, E.K.1
Barker, T.J.2
Duncan, K.K.3
Boger, D.L.4
-
38
-
-
84872772908
-
A remarkable series of vinblastine analogues displaying enhanced activity and an unprecedented tubulin binding steric tolerance: C20′ urea derivatives
-
Leggans, E. K.; Duncan, K. K.; Barker, T. J.; Schleicher, K. D.; Boger, D. L. A remarkable series of vinblastine analogues displaying enhanced activity and an unprecedented tubulin binding steric tolerance: C20′ urea derivatives J. Med. Chem. 2013, 56, 628-639
-
(2013)
J. Med. Chem.
, vol.56
, pp. 628-639
-
-
Leggans, E.K.1
Duncan, K.K.2
Barker, T.J.3
Schleicher, K.D.4
Boger, D.L.5
-
39
-
-
84885457038
-
Potent vinblastine C20′ ureas displaying additionally improved activity against a vinblastine-resistant cancer cell line
-
Barker, T. J.; Duncan, K. K.; Otrubova, K.; Boger, D. L. Potent vinblastine C20′ ureas displaying additionally improved activity against a vinblastine-resistant cancer cell line ACS Med. Chem. Lett. 2013, 4, 985-988
-
(2013)
ACS Med. Chem. Lett.
, vol.4
, pp. 985-988
-
-
Barker, T.J.1
Duncan, K.K.2
Otrubova, K.3
Boger, D.L.4
-
40
-
-
77958045870
-
Catharanthine C16 substituent effects on the biomimetic coupling with vindoline: Preparation and evaluation of a key series of vinblastine analogues
-
Tam, A.; Gotoh, H.; Robertson, W. M.; Boger, D. L. Catharanthine C16 substituent effects on the biomimetic coupling with vindoline: preparation and evaluation of a key series of vinblastine analogues Bioorg. Med. Chem. Lett. 2010, 20, 6408-6410
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 6408-6410
-
-
Tam, A.1
Gotoh, H.2
Robertson, W.M.3
Boger, D.L.4
-
41
-
-
83455258222
-
10′-Fluorovinblastine and 10′-fluorovincristine: Synthesis of a key series of modified Vinca alkaloids
-
Gotoh, H.; Duncan, K. K.; Robertson, W. M.; Boger, D. L. 10′-Fluorovinblastine and 10′-fluorovincristine: synthesis of a key series of modified Vinca alkaloids ACS Med. Chem. Lett. 2011, 2, 948-952
-
(2011)
ACS Med. Chem. Lett.
, vol.2
, pp. 948-952
-
-
Gotoh, H.1
Duncan, K.K.2
Robertson, W.M.3
Boger, D.L.4
-
42
-
-
84865120407
-
New insights into the mechanism and an expanded scope of the Fe(III)-mediated vinblastine coupling reaction
-
Gotoh, H.; Sears, J. E.; Eschenmoser, A.; Boger, D. L. New insights into the mechanism and an expanded scope of the Fe(III)-mediated vinblastine coupling reaction J. Am. Chem. Soc. 2012, 134, 13240-13243
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 13240-13243
-
-
Gotoh, H.1
Sears, J.E.2
Eschenmoser, A.3
Boger, D.L.4
-
43
-
-
84925427559
-
-
note
-
We thank Gregory Vite and Robert Borzilleri for arranging and overseeing this assessment and Craig Fairchild, Kathy Johnson, and Russell Peterson for conducting the testing at Bristol-Myers Squibb.
-
-
-
-
44
-
-
19544393159
-
Structural basis for the regulation of tublin by vinblastine
-
Gigant, B.; Wang, C.; Ravelli, R. B. G.; Roussi, F.; Steinmetz, M. O.; Curmi, P. A.; Sobel, A.; Knossow, M. Structural basis for the regulation of tublin by vinblastine Nature 2005, 435, 519-522
-
(2005)
Nature
, vol.435
, pp. 519-522
-
-
Gigant, B.1
Wang, C.2
Ravelli, R.B.G.3
Roussi, F.4
Steinmetz, M.O.5
Curmi, P.A.6
Sobel, A.7
Knossow, M.8
-
45
-
-
84893442643
-
Simple, chemoselective hydrogenation with thermodynamic stereocontrol
-
Iwasaki, K.; Wan, K. K.; Oppedisano, A.; Crossley, S. W. M.; Shenvi, R. A. Simple, chemoselective hydrogenation with thermodynamic stereocontrol J. Am. Chem. Soc. 2014, 136, 1300-1303
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 1300-1303
-
-
Iwasaki, K.1
Wan, K.K.2
Oppedisano, A.3
Crossley, S.W.M.4
Shenvi, R.A.5
-
46
-
-
84893467790
-
A practical and catalytic reductive olefin coupling
-
Lo, J. C.; Yabe, Y.; Baran, P. S. A practical and catalytic reductive olefin coupling J. Am. Chem. Soc. 2014, 136, 1304
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 1304
-
-
Lo, J.C.1
Yabe, Y.2
Baran, P.S.3
-
47
-
-
84865431754
-
4-mediated free radical hydrofluorination of unactivated alkenes
-
4-mediated free radical hydrofluorination of unactivated alkenes J. Am. Chem. Soc. 2012, 134, 13588-13591
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 13588-13591
-
-
Barker, T.J.1
Boger, D.L.2
-
48
-
-
0001278411
-
Total synthesis of azafluoranthene alkaloids: Rufescine and imelutine
-
Boger, D. L.; Brotherton, C. E. Total synthesis of azafluoranthene alkaloids: rufescine and imelutine J. Org. Chem. 1984, 49, 4050-4055
-
(1984)
J. Org. Chem.
, vol.49
, pp. 4050-4055
-
-
Boger, D.L.1
Brotherton, C.E.2
-
49
-
-
0036086184
-
Novel aspects of natural and modified Vinca alkaloids
-
Duflos, A.; Kruczynski, A.; Baret, J.-M. Novel aspects of natural and modified Vinca alkaloids Curr. Med. Chem., Anti-Cancer Agents 2002, 2, 55-75
-
(2002)
Curr. Med. Chem., Anti-Cancer Agents
, vol.2
, pp. 55-75
-
-
Duflos, A.1
Kruczynski, A.2
Baret, J.-M.3
-
50
-
-
84886305653
-
Transannular Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles: Total synthesis of a unique set of vinblastine analogues
-
Campbell, E. L.; Skepper, C. K.; Sankar, K.; Duncan, K. K.; Boger, D. L. Transannular Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles: total synthesis of a unique set of vinblastine analogues Org. Lett. 2013, 15, 5306-5309
-
(2013)
Org. Lett.
, vol.15
, pp. 5306-5309
-
-
Campbell, E.L.1
Skepper, C.K.2
Sankar, K.3
Duncan, K.K.4
Boger, D.L.5
-
51
-
-
77956985981
-
Vinca drug components accumulate exclusively in leaf exudates of Madagascar periwinkle
-
Roepke, J.; Salim, V.; Wu, M.; Thamm, A. M. K.; Murata, J.; Ploss, K.; Boland, W.; De Luca, V. Vinca drug components accumulate exclusively in leaf exudates of Madagascar periwinkle Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 15287-15292
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 15287-15292
-
-
Roepke, J.1
Salim, V.2
Wu, M.3
Thamm, A.M.K.4
Murata, J.5
Ploss, K.6
Boland, W.7
De Luca, V.8
-
52
-
-
84925427558
-
-
note
-
Once in a while you receive a valued gift if you ask the right question at the right time. Personal communication: Otis, Hutchinson, KS (1971).
-
-
-
|