Syntheses and biological evaluation of vinblastine congeners

Organic and Biomolecular Chemistry

Volumn 1, Issue 12, 2003, Pages 2120-2136

  Kuehne, Martin E ^a   Bornmann, William G ^a   Markó, Istvan ^a   Qin, Yong ^a   LeBoulluec, Karen L ^a   Frasier, Deborah A ^a   Xu, Feng ^a   Mulamba, Tshilundu ^a   Ensinger, Carol L ^a   Borman, Linda S ^b   Huot, Anne E ^a   Exon, Christopher ^c   Bizzarro, Fred T ^c   Cheung, Julia B ^c   Bane, Susan L ^d  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

^d STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL MATERIALS; CELLS; CONFORMATIONS; POLYMERIZATION; PROTEINS; STEREOCHEMISTRY; STOICHIOMETRY; SYNTHESIS (CHEMICAL); TOXICITY;

CARBOMETHOXYCLEAVAMINE MOIETY; CYCTOXICITY; PIPERIDINE RING; VINBLASTINE CONGENERS;

ORGANIC COMPOUNDS;

MURINAE;

ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; VINBLASTINE;

ADENOCARCINOMA; ANIMAL; ARTICLE; CHEMISTRY; COLON TUMOR; DRUG EFFECT; DRUG SCREENING; IC 50; LEUKEMIA L 1210; MICROTUBULE; MOUSE; RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; COLONIC NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; INHIBITORY CONCENTRATION 50; LEUKEMIA L1210; MICE; MICROTUBULES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; VINBLASTINE;

EID: 0142010038     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b209990j     Document Type: Article

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