Characteristics and a functional implication of Ca2+-activated K+ current in mouse aortic endothelial cells

Pflugers Archiv European Journal of Physiology

Volumn 447, Issue 4, 2004, Pages 426-435

  Ahn, Seung Cheol ^b   Seol, Geun Hee ^a   Kim, Ji Aee ^a   Suh, Suk Hyo ^a  

^a Ewha Womans University School of Medicine   (South Korea)

^b Dankook University   (South Korea)

Author keywords

Ca2+ activated K+ current; Endothelium dependent relaxation; IKCa channel inhibitors; IKCa channel openers; mIK1; Mouse aortic endothelial cell

Indexed keywords

1 ETHYL 2 BENZIMIDAZOLINONE; APAMIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; CHARYBDOTOXIN; CHLORIDE CHANNEL BLOCKING AGENT; CHLORZOXAZONE; CLOTRIMAZOLE; ECONAZOLE; IBERIOTOXIN; NIFLUMIC ACID; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; POTASSIUM ION; TETRYLAMMONIUM; ZOXAZOLAMINE;

ANIMAL CELL; AORTA; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENDOTHELIUM CELL; INHIBITION KINETICS; MEMBRANE CURRENT; MOUSE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PREDICTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE RELAXATION;

ANIMALS; AORTA; CALCIUM; CELLS, CULTURED; CHLORIDE CHANNELS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; MALE; MICE; MUSCLE RELAXANTS, CENTRAL; MUSCLE RELAXATION; NIFLUMIC ACID; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED;

EID: 0942279568     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-003-1201-1     Document Type: Article

References (37)

1. Adams DJ, Barakeh J, Laskey R, Van Breemen C (1989) Ion channels and regulation of intracellular calcium in vascular endothelial cells. FASEB J 3:2389-2400
2. Busch AE, Herzer T, Wagner CA, Schmidt F, Raber G, Waldegger S, Lang F (1994) Positive regulation by chloride channel blockers of IsK channels expressed in Xenopus oocytes. Mol Pharmacol 46:750-753
3. + channel in porcine coronary endothelium: relevance to EDHF. Br J Pharmacol 137:1346-1354
4. 2+) channel of intermediate conductance in bovine aortic endothelial cells. J Membr Biol 163:147-158
5. - channels as well as nonselective, stretch-activated cation channels in Ehrlich ascites tumor cells. J Membr Biol 129:13-36
6. + current by the oncogenic receptor protein tyrosine kinase v-Fms in mouse fibroblasts. Naunyn Schmiedeberg's Arch Pharmacol 357:378-384
7. + channel in colonic secretory cells. Am J Physiol 265:C1271-C1280
8. +-channels suppresses EDHF-mediated vasodilation. Br J Pharmacol 138:594-601
9. Farrugia G, Rae JL, Szurszewski JH (1993) Characterization of an outward potassium current in canine jejunal circular smooth muscle and its activation by fenamates. J Physiol (Lond) 468:297-310
10. Gribkoff VK, Lum-Ragan JT, Boissard CG, Post-Munson DJ, Meanwell NA, Starrett JE Jr, Kozlowski ES, Romine JL, Trojnacki JT, McKay MC, Zhong J, Dworetzky SI (1996) Effects of channel modulators on cloned large-conductance calcium-activated potassium channels. Mol Pharmacol 50:206-217
11. Ishii TM, Silvia C, Hirschberg B, Bond CT, Adelman JP, Maylie J (1997) A human intermediate conductance calcium-activated potassium channel. Proc Natl Acad Sci USA 94:11651-11656
12. + channel. Am J Physiol 275:C848-C856
13. Joiner WJ, Wang LY, Tang MD, Kaczmarek LK (1997) hSK4, a member of a novel subfamily of calcium-activated potassium channels. Proc Natl Acad Sci USA 94:11013-11018
14. 2+ concentration in agonist-activated endothelial cells. Gen Physiol Biophys 18:199-208
15. Kohler M, Hirschberg B, Bond CT, Kinzie JM, Marrion NV, Maylie J, Adelman JP (1996) Small-conductance, calcium-activated potassium channels from mammalian brain. Science 273:1709-1714
16. + channels in human mesenteric artery: a single-cell reverse transcriptase- polymerase chain reaction and electrophysiological study in situ. Circ Res 87:496-503
17. + channels depolarize human T lymphocytes: mechanism of the antiproliferative effect of charybdotoxin. Proc Natl Acad Sci USA 89:10094-10098
18. Lewis RS, Cahalan MD (1995) Potassium and calcium channels in lymphocytes. Annu Rev Immunol 13:623-653
19. Logsdon NJ, Kang J, Togo JA, Christian EP, Aiyar J (1997) A novel gene, hKCa4, encodes the calcium-activated potassium channel in human T lymphocytes. J Biol Chem 272:32723-32726
20. Luckhoff A, Busse R (1990) Calcium influx into endothelial cells and formation of endothelium-derived relaxing factor is controlled by the membrane potential. Pflugers Arch 416:305-311
21. Manolopoulos VG, Liu J, Unsworth BR, Lelkes PI (1995) Adenylyl cyclase isoforms are differentially expressed in primary cultures of endothelial cells and whole tissue homogenates from various rat tissues. Biochem Biophys Res Commun 208:323-331
22. + channels. Bull Exp Biol Med 134:422-424
23. + channel-blocking peptides. Neuron 15:5-10
24. Nilius B, Droogmans G (2001) Ion channels and their functional role in vascular endothelium. Physiol Rev 81:1415-1459
25. Nilius B, Riemann D (1990) Ion channels in human endothelial cells. Gen Physiol Biophys 9:89-111
26. 2+ transients in endothelial cells from human umbilical vein. Pflugers Arch 424:285-293
27. - current by hypotonic volume increase in human endothelial cells. J Gen Physiol 103:787-805
28. Ca channels by niflumic, flufenamic, and mefenamic acids. Biophys J 67:2272-2279
29. Pena TL, Rane SG (1997) The small conductance calcium-activated potassium channel regulates ion channel expression in C3H10T1/2 cells ectopically expressing the muscle regulatory factor MRF4. J Biol Chem 272:21909-21916
30. + channels in postischaemic heart. Clin Exp Pharmacol Physiol 29:324-329
31. Schilling WP (1989) Effect of membrane potential on cytosolic calcium of bovine aortic endothelial cells. Am J Physiol 257: H778-H784
32. Ca channel activated by bradykinin and substance P in endothelial cells. Br J Pharmacol 136:1201-1209
33. + induced relaxation in various arteries. Korean J Physiol Pharmacol 3:415-425
34. 2+ signalling. Pflugers Arch 438:612-620
35. + currents in bovine parotid acinar cells. Am J Physiol 284:C127-C144
36. + channel with inward rectifying properties in brain microvascular endothelial cells: properties and activation by endothelins. J Neurochem 65:1274-1281
37. + channel (rSK4) of colonic crypts. Pflugers Arch 438:437-444