The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 12, 2015, Pages 3698-3703

  Bai, Fang ^a   Morcos, Faruck ^a   Sohn, Yang Sung ^b   Darash Yahana, Merav ^b   Rezende, Celso O ^c   Lipper, Colin H ^c   Paddock, Mark L ^c   Song, Luhua ^d   Luo, Yuting ^d   Holt, Sarah H ^d   Tamir, Sagi ^b   Theodorakis, Emmanuel A ^c   Jennings, Patricia A ^c   Onuchic, José N ^a   Mittler, Ron ^d   Nechushtai, Rachel ^b,d  

^a RICE UNIVERSITY   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

Iron sulfur proteins; Mitocan; Mitochondria; Neet proteins; Rational drug design

Indexed keywords

ANTINEOPLASTIC AGENT; CLUVENONE; DOCKING PROTEIN; DRUG BINDING PROTEIN; FIBRINOGEN; IRON SULFUR PROTEIN; MAD 28; MAD 44; MITONEET PROTEIN; NUTRIENT DEPRIVATION AUTOPHAGY FACTOR 1; PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; CISD1 PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; NAF1 PROTEIN, HUMAN; RIBONUCLEOPROTEIN; XANTHONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; BREAST CANCER; BREAST CELL; CANCER CHEMOTHERAPY; CELL FUNCTION; CELL KILLING; CELL METABOLISM; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CLUSTER ANALYSIS; CONTROLLED STUDY; DRUG SENSITIVITY; DRUG SPECIFICITY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TARGET CELL; BREAST NEOPLASMS; CELL SURVIVAL; CHEMISTRY; COMPUTER PROGRAM; CONFORMATION; DRUG DESIGN; FEMALE; MCF 7 CELL LINE; MOLECULAR DOCKING; MOLECULARLY TARGETED THERAPY; TUMOR CELL LINE;

CARNATION LATENT VIRUS;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CLUSTER ANALYSIS; DRUG DESIGN; FEMALE; HUMANS; IRON-SULFUR PROTEINS; MCF-7 CELLS; MITOCHONDRIAL PROTEINS; MOLECULAR CONFORMATION; MOLECULAR DOCKING SIMULATION; MOLECULAR TARGETED THERAPY; RIBONUCLEOPROTEINS; SOFTWARE; XANTHONES;

EID: 84925434840     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1502960112     Document Type: Article

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