MitoNEET is a uniquely folded 2Fe-2S outer mitochondrial membrane protein stabilized by pioglitazone

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 36, 2007, Pages 14342-14347

  Paddock, Mark L ^a   Wiley, Sandra E ^a   Axelrod, Herbert L ^b   Cohen, Aina E ^b   Roy, Melinda ^a   Abresch, Edward C ^a   Capraro, Dominique ^a   Murphy, Anne N ^a   Nechushtai, Rachel ^c   Dixon, Jack E ^a   Jennings, Patricia A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Diabetes; FeS cluster; Iron homeostasis; Oxidative stress; Thiazolidinedione

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; INSULIN SENSITIZING AGENT; IRON; IRON SULFUR PROTEIN; MEMBRANE PROTEIN; PIOGLITAZONE; IRON BINDING PROTEIN; MITOCHONDRIAL PROTEIN; UNCLASSIFIED DRUG; ZCD1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIABETES MELLITUS; DRUG PROTEIN BINDING; HUMAN; INSULIN RESISTANCE; IRON TRANSPORT; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN STRUCTURE; X RAY DIFFRACTION; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MITOCHONDRIAL MEMBRANE; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; HUMANS; IRON-BINDING PROTEINS; IRON-SULFUR PROTEINS; MEMBRANE PROTEINS; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; THIAZOLIDINEDIONES;

EID: 35448995690     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0707189104     Document Type: Article

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