Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 32, 2011, Pages 13047-13052

  Zuris, John A ^a   Harir, Yael ^b   Conlan, Andrea R ^a   Shvartsman, Maya ^b   Michaeli, Dorit ^b   Tamir, Sagi ^b   Paddock, Mark L ^a   Onuchic, José N ^a   Mittler, Ron ^b,c   Cabantchik, Zvi Ioav ^b   Jennings, Patricia A ^a   Nechushtai, Rachel ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

CISD1; Diabetes; FeS cluster; Oxidative stress

Indexed keywords

CARRIER PROTEIN; CYSTINE; FERREDOXIN; HISTIDINE; IRON SULFUR PROTEIN; LYSINE; PIOGLITAZONE;

ARTICLE; BIOASSAY; CELL STRAIN HEK293; CONTROLLED STUDY; DIABETES MELLITUS; DRUG TARGETING; EMBRYO; HUMAN; HUMAN CELL; IRON OVERLOAD; MITOCHONDRION; MUTAGENESIS; MUTANT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; ULTRAVIOLET SPECTROSCOPY;

FERREDOXINS; HEK293 CELLS; HISTIDINE; HUMANS; HYPOGLYCEMIC AGENTS; IRON; IRON-SULFUR PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; MUTANT PROTEINS; OXIDATION-REDUCTION; PERMEABILITY; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINEDIONES;

EID: 80051994547     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1109986108     Document Type: Article

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