A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties

Acta Crystallographica Section D: Biological Crystallography

Volumn 70, Issue 6, 2014, Pages 1572-1578

  Tamir, Sagi ^a   Eisenberg Domovich, Yael ^a   Conlan, Andrea R ^b   Stofleth, Jason T ^b   Lipper, Colin H ^b   Paddock, Mark L ^b   Mittler, Ron ^c   Jennings, Patricia A ^b   Livnah, Oded ^a   Nechushtai, Rachel ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

2Fe 2S cluster transfer and cluster stability; autophagy; breast cancer; longevity; redox potential; WFS2

Indexed keywords

IRON SULFUR PROTEIN; LIGAND;

CHEMISTRY; GENETICS; METABOLISM; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; POINT MUTATION; ULTRAVIOLET SPECTROPHOTOMETRY; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; IRON-SULFUR PROTEINS; LIGANDS; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; POINT MUTATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84902492778     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S1399004714005458     Document Type: Article

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