-
1
-
-
25444432780
-
Avian influenza A (H5N1) infection in humans
-
Beigel JH, Farrar J, Han AM, Hayden FG, Hyer R, de Jong MD, Lochindarat S, Nguyen TK, Nguyen TH, Tran TH, Nicoll A, Touch S, Yuen KY, Writing Committee of the World Health Organization (WHO) Consultation on Human Influenza A/H5. 2005. Avian influenza A (H5N1) infection in humans. N Engl J Med 353:1374-1385. http://dx.doi.org/10.1056/NEJMra052211.
-
(2005)
N Engl J Med
, vol.353
, pp. 1374-1385
-
-
Beigel, J.H.1
Farrar, J.2
Han, A.M.3
Hayden, F.G.4
Hyer, R.5
de Jong, M.D.6
Lochindarat, S.7
Nguyen, T.K.8
Nguyen, T.H.9
Tran, T.H.10
Nicoll, A.11
Touch, S.12
Yuen, K.Y.13
-
2
-
-
38349068756
-
Update on avian influenza A (H5N1) virus infection in humans
-
Writing Committee of the Second World Health Organization Consultation on Clinical Aspects of Human Infection with Avian Influenza A (H5N1) Virus, Abdel-Ghafar AN, Chotpitayasunondh T, Gao Z, Hayden FG, Nguyen DH, de Jong MD, Naghdaliyev A, Peiris JS, Shindo N, Soeroso S, Uyeki TM. 2008. Update on avian influenza A (H5N1) virus infection in humans. N Engl J Med 358:261-273. http://dx.doi.org/10.1056/NEJMra0707279.
-
(2008)
N Engl J Med
, vol.358
, pp. 261-273
-
-
Abdel-Ghafar, A.N.1
Chotpitayasunondh, T.2
Gao, Z.3
Hayden, F.G.4
Nguyen, D.H.5
de Jong, M.D.6
Naghdaliyev, A.7
Peiris, J.S.8
Shindo, N.9
Soeroso, S.10
Uyeki, T.M.11
-
3
-
-
42649132198
-
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China
-
Wang H, Feng Z, Shu Y, Yu H, Zhou L, Zu R, Huai Y, Dong J, Bao C, Wen L, Wang H, Yang P, Zhao W, Dong L, Zhou M, Liao Q, Yang H, Wang M, Lu X, Shi Z, Wang W, Gu L, Zhu F, Li Q, Yin W, Yang W, Li D, Uyeki TM, Wang Y. 2008. Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet 371:1427-1434. http://dx.doi.org/10.1016/S0140-6736(08)60493-6.
-
(2008)
Lancet
, vol.371
, pp. 1427-1434
-
-
Wang, H.1
Feng, Z.2
Shu, Y.3
Yu, H.4
Zhou, L.5
Zu, R.6
Huai, Y.7
Dong, J.8
Bao, C.9
Wen, L.10
Wang, H.11
Yang, P.12
Zhao, W.13
Dong, L.14
Zhou, M.15
Liao, Q.16
Yang, H.17
Wang, M.18
Lu, X.19
Shi, Z.20
Wang, W.21
Gu, L.22
Zhu, F.23
Li, Q.24
Yin, W.25
Yang, W.26
Li, D.27
Uyeki, T.M.28
Wang, Y.29
more..
-
4
-
-
19944432232
-
Probable person-to-person transmission of avian influenza A (H5N1)
-
Ungchusak K, Auewarakul P, Dowell SF, Kitphati R, Auwanit W, Puthavathana P, Uiprasertkul M, Boonnak K, Pittayawonganon C, Cox NJ, Zaki SR, Thawatsupha P, Chittaganpitch M, Khontong R, Simmerman JM, Chunsutthiwat S. 2005. Probable person-to-person transmission of avian influenza A (H5N1). N Engl J Med 352:333-340. http://dx.doi.org/10.1056/NEJMoa044021.
-
(2005)
N Engl J Med
, vol.352
, pp. 333-340
-
-
Ungchusak, K.1
Auewarakul, P.2
Dowell, S.F.3
Kitphati, R.4
Auwanit, W.5
Puthavathana, P.6
Uiprasertkul, M.7
Boonnak, K.8
Pittayawonganon, C.9
Cox, N.J.10
Zaki, S.R.11
Thawatsupha, P.12
Chittaganpitch, M.13
Khontong, R.14
Simmerman, J.M.15
Chunsutthiwat, S.16
-
5
-
-
80053398495
-
Biochemical impact of the host adaptation-associated PB2 E627K mutation on the temperature-dependent RNA synthesis kinetics of influenza A virus polymerase complex
-
Aggarwal S, Dewhurst S, Takimoto T, Kim B. 2011. Biochemical impact of the host adaptation-associated PB2 E627K mutation on the temperature-dependent RNA synthesis kinetics of influenza A virus polymerase complex. J Biol Chem 286:34504-34513. http://dx.doi.org/10.1074/jbc.M111.262048.
-
(2011)
J Biol Chem
, vol.286
, pp. 34504-34513
-
-
Aggarwal, S.1
Dewhurst, S.2
Takimoto, T.3
Kim, B.4
-
6
-
-
59249096926
-
Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N
-
Steel J, Lowen AC, Mubareka S, Palese P. 2009. Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N. PLoS Pathog 5:e1000252. http://dx.doi.org/10.1371/journal.ppat.1000252.
-
(2009)
PLoS Pathog
, vol.5
-
-
Steel, J.1
Lowen, A.C.2
Mubareka, S.3
Palese, P.4
-
7
-
-
36049011840
-
Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice
-
Hatta M, Hatta Y, Kim JH, Watanabe S, Shinya K, Nguyen T, Lien PS, Le QM, Kawaoka Y. 2007. Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice. PLoS Pathog 3:1374-1379. http://dx.doi.org/10.1371/journal.ppat.0030133.
-
(2007)
PLoS Pathog
, vol.3
, pp. 1374-1379
-
-
Hatta, M.1
Hatta, Y.2
Kim, J.H.3
Watanabe, S.4
Shinya, K.5
Nguyen, T.6
Lien, P.S.7
Le, Q.M.8
Kawaoka, Y.9
-
8
-
-
77958149212
-
Biological and structural characterization of a hostadapting amino acid in influenza virus
-
Yamada S, Hatta M, Staker BL, Watanabe S, Imai M, Shinya K, Sakai-Tagawa Y, Ito M, Ozawa M, Watanabe T, Sakabe S, Li C, Kim JH, Myler PJ, Phan I, Raymond A, Smith E, Stacy R, Nidom CA, Lank SM, Wiseman RW, Bimber BN, O'Connor DH, Neumann G, Stewart LJ, Kawaoka Y. 2010. Biological and structural characterization of a hostadapting amino acid in influenza virus. PLoS Pathog 6:e1001034. http://dx.doi.org/10.1371/journal.ppat.1001034.
-
(2010)
PLoS Pathog
, vol.6
-
-
Yamada, S.1
Hatta, M.2
Staker, B.L.3
Watanabe, S.4
Imai, M.5
Shinya, K.6
Sakai-Tagawa, Y.7
Ito, M.8
Ozawa, M.9
Watanabe, T.10
Sakabe, S.11
Li, C.12
Kim, J.H.13
Myler, P.J.14
Phan, I.15
Raymond, A.16
Smith, E.17
Stacy, R.18
Nidom, C.A.19
Lank, S.M.20
Wiseman, R.W.21
Bimber, B.N.22
O'Connor, D.H.23
Neumann, G.24
Stewart, L.J.25
Kawaoka, Y.26
more..
-
9
-
-
24644484686
-
Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model
-
Li Z, Chen H, Jiao P, Deng G, Tian G, Li Y, Hoffmann E, Webster RG, Matsuoka Y, Yu K. 2005. Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model. J Virol 79:12058-12064. http://dx.doi.org/10.1128/JVI.79.18.12058-12064.2005.
-
(2005)
J Virol
, vol.79
, pp. 12058-12064
-
-
Li, Z.1
Chen, H.2
Jiao, P.3
Deng, G.4
Tian, G.5
Li, Y.6
Hoffmann, E.7
Webster, R.G.8
Matsuoka, Y.9
Yu, K.10
-
10
-
-
77950835010
-
PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells
-
Bussey KA, Bousse TL, Desmet EA, Kim B, Takimoto T. 2010. PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells. J Virol 84:4395-4406. http://dx.doi.org/10.1128/JVI.02642-09.
-
(2010)
J Virol
, vol.84
, pp. 4395-4406
-
-
Bussey, K.A.1
Bousse, T.L.2
Desmet, E.A.3
Kim, B.4
Takimoto, T.5
-
11
-
-
78650037441
-
PB2 residue 158 is a pathogenic determinant of pandemic H1N1 and H5 influenza a viruses in mice
-
Zhou B, Li Y, Halpin R, Hine E, Spiro DJ, Wentworth DE. 2011. PB2 residue 158 is a pathogenic determinant of pandemic H1N1 and H5 influenza a viruses in mice. J Virol 85:357-365. http://dx.doi.org/10.1128/JVI.01694-10.
-
(2011)
J Virol
, vol.85
, pp. 357-365
-
-
Zhou, B.1
Li, Y.2
Halpin, R.3
Hine, E.4
Spiro, D.J.5
Wentworth, D.E.6
-
12
-
-
84923351054
-
Novel residues in avian influenza virus PB2 protein affect virulence in mammalian hosts
-
Fan S, Hatta M, Kim JH, Halfmann P, Imai M, Macken CA, Le MQ, Nguyen T, Neumann G, Kawaoka Y. 2014. Novel residues in avian influenza virus PB2 protein affect virulence in mammalian hosts. Nat Commun 5:5021. http://dx.doi.org/10.1038/ncomms6021.
-
(2014)
Nat Commun
, vol.5
, pp. 5021
-
-
Fan, S.1
Hatta, M.2
Kim, J.H.3
Halfmann, P.4
Imai, M.5
Macken, C.A.6
Le, M.Q.7
Nguyen, T.8
Neumann, G.9
Kawaoka, Y.10
-
13
-
-
84857098515
-
Reassortment and mutation of the avian influenza virus polymerase PA subunit overcome species barriers
-
Mehle A, Dugan VG, Taubenberger JK, Doudna JA. 2012. Reassortment and mutation of the avian influenza virus polymerase PA subunit overcome species barriers. J Virol 86:1750-1757. http://dx.doi.org/10.1128/JVI.06203-11.
-
(2012)
J Virol
, vol.86
, pp. 1750-1757
-
-
Mehle, A.1
Dugan, V.G.2
Taubenberger, J.K.3
Doudna, J.A.4
-
14
-
-
84880865579
-
Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30
-
Dankar SK, Miranda E, Forbes NE, Pelchat M, Tavassoli A, Selman M, Ping J, Jia J, Brown EG. 2013. Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30. Virol J 10:243. http://dx.doi.org/10.1186/1743-422X-10-243.
-
(2013)
Virol J
, vol.10
, pp. 243
-
-
Dankar, S.K.1
Miranda, E.2
Forbes, N.E.3
Pelchat, M.4
Tavassoli, A.5
Selman, M.6
Ping, J.7
Jia, J.8
Brown, E.G.9
-
15
-
-
84871007119
-
Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells
-
Mänz B, Brunotte L, Reuther P, Schwemmle M. 2012. Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells. Nat Commun 3:802. http://dx.doi.org/10.1038/ncomms1804.
-
(2012)
Nat Commun
, vol.3
, pp. 802
-
-
Mänz, B.1
Brunotte, L.2
Reuther, P.3
Schwemmle, M.4
-
16
-
-
84863158873
-
Amino acids 473V and 598P of PB1 from an avian-origin influenza A virus contribute to polymerase activity, especially in mammalian cells
-
Xu C, Hu WB, Xu K, He YX, Wang TY, Chen Z, Li TX, Liu JH, Buchy P, Sun B. 2012. Amino acids 473V and 598P of PB1 from an avian-origin influenza A virus contribute to polymerase activity, especially in mammalian cells. J Gen Virol 93:531-540. http://dx.doi.org/10.1099/vir.0.036434-0.
-
(2012)
J Gen Virol
, vol.93
, pp. 531-540
-
-
Xu, C.1
Hu, W.B.2
Xu, K.3
He, Y.X.4
Wang, T.Y.5
Chen, Z.6
Li, T.X.7
Liu, J.H.8
Buchy, P.9
Sun, B.10
-
17
-
-
70450170087
-
The polymerase acidic protein gene of influenza a virus contributes to pathogenicity in a mouse model
-
Song MS, Pascua PN, Lee JH, Baek YH, Lee OJ, Kim CJ, Kim H, Webby RJ, Webster RG, Choi YK. 2009. The polymerase acidic protein gene of influenza a virus contributes to pathogenicity in a mouse model. J Virol 83:12325-12335. http://dx.doi.org/10.1128/JVI.01373-09.
-
(2009)
J Virol
, vol.83
, pp. 12325-12335
-
-
Song, M.S.1
Pascua, P.N.2
Lee, J.H.3
Baek, Y.H.4
Lee, O.J.5
Kim, C.J.6
Kim, H.7
Webby, R.J.8
Webster, R.G.9
Choi, Y.K.10
-
18
-
-
77951043137
-
Role of host-specific amino acids in the pathogenicity of avian H5N1 influenza viruses in mice
-
Kim JH, Hatta M, Watanabe S, Neumann G, Watanabe T, Kawaoka Y. 2010. Role of host-specific amino acids in the pathogenicity of avian H5N1 influenza viruses in mice. J Gen Virol 91:1284-1289. http://dx.doi.org/10.1099/vir.0.018143-0.
-
(2010)
J Gen Virol
, vol.91
, pp. 1284-1289
-
-
Kim, J.H.1
Hatta, M.2
Watanabe, S.3
Neumann, G.4
Watanabe, T.5
Kawaoka, Y.6
-
19
-
-
84874708826
-
The PA-gene-mediated lethal dissemination and excessive innate immune response contribute to the high virulence of H5N1 avian influenza virus in mice
-
Hu J, Hu Z, Song Q, Gu M, Liu X, Wang X, Hu S, Chen C, Liu H, Liu W, Chen S, Peng D, Liu X. 2013. The PA-gene-mediated lethal dissemination and excessive innate immune response contribute to the high virulence of H5N1 avian influenza virus in mice. J Virol 87:2660-2672. http://dx.doi.org/10.1128/JVI.02891-12.
-
(2013)
J Virol
, vol.87
, pp. 2660-2672
-
-
Hu, J.1
Hu, Z.2
Song, Q.3
Gu, M.4
Liu, X.5
Wang, X.6
Hu, S.7
Chen, C.8
Liu, H.9
Liu, W.10
Chen, S.11
Peng, D.12
Liu, X.13
-
20
-
-
34547779411
-
Molecular changes in the polymerase genes (PA and PB1) associated with high pathogenicity of H5N1 influenza virus in mallard ducks
-
Hulse-Post DJ, Franks J, Boyd K, Salomon R, Hoffmann E, Yen HL, Webby RJ, Walker D, Nguyen TD, Webster RG. 2007. Molecular changes in the polymerase genes (PA and PB1) associated with high pathogenicity of H5N1 influenza virus in mallard ducks. J Virol 81:8515-8524. http://dx.doi.org/10.1128/JVI.00435-07.
-
(2007)
J Virol
, vol.81
, pp. 8515-8524
-
-
Hulse-Post, D.J.1
Franks, J.2
Boyd, K.3
Salomon, R.4
Hoffmann, E.5
Yen, H.L.6
Webby, R.J.7
Walker, D.8
Nguyen, T.D.9
Webster, R.G.10
-
21
-
-
77950952992
-
Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity
-
Leung BW, Chen H, Brownlee GG. 2010. Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity. Virology 401:96-106. http://dx.doi.org/10.1016/j.virol.2010.01.036.
-
(2010)
Virology
, vol.401
, pp. 96-106
-
-
Leung, B.W.1
Chen, H.2
Brownlee, G.G.3
-
22
-
-
84555178398
-
Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice
-
Seyer R, Hrincius ER, Ritzel D, Abt M, Mellmann A, Marjuki H, Kühn J, Wolff T, Ludwig S, Ehrhardt C. 2012. Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice. J Infect Dis 205:262-271. http://dx.doi.org/10.1093/infdis/jir716.
-
(2012)
J Infect Dis
, vol.205
, pp. 262-271
-
-
Seyer, R.1
Hrincius, E.R.2
Ritzel, D.3
Abt, M.4
Mellmann, A.5
Marjuki, H.6
Kühn, J.7
Wolff, T.8
Ludwig, S.9
Ehrhardt, C.10
-
23
-
-
84863233974
-
Mutations in polymerase genes enhanced the virulence of 2009 pandemic H1N1 influenza virus in mice
-
Zhu W, Zhu Y, Qin K, Yu Z, Gao R, Yu H, Zhou J, Shu Y. 2012. Mutations in polymerase genes enhanced the virulence of 2009 pandemic H1N1 influenza virus in mice. PLoS One 7:e33383. http://dx.doi.org/10.1371/journal.pone.0033383.
-
(2012)
PLoS One
, vol.7
-
-
Zhu, W.1
Zhu, Y.2
Qin, K.3
Yu, Z.4
Gao, R.5
Yu, H.6
Zhou, J.7
Shu, Y.8
-
24
-
-
77956625295
-
Adaptation of pandemic H1N1 influenza viruses in mice
-
Ilyushina NA, Khalenkov AM, Seiler JP, Forrest HL, Bovin NV, Marjuki H, Barman S, Webster RG, Webby RJ. 2010. Adaptation of pandemic H1N1 influenza viruses in mice. J Virol 84:8607-8616. http://dx.doi.org/10.1128/JVI.00159-10.
-
(2010)
J Virol
, vol.84
, pp. 8607-8616
-
-
Ilyushina, N.A.1
Khalenkov, A.M.2
Seiler, J.P.3
Forrest, H.L.4
Bovin, N.V.5
Marjuki, H.6
Barman, S.7
Webster, R.G.8
Webby, R.J.9
-
25
-
-
79956295593
-
Mutations in PA, NP, andHAof a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice
-
Sakabe S, Ozawa M, Takano R, Iwastuki-Horimoto K, Kawaoka Y. 2011. Mutations in PA, NP, andHAof a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice. Virus Res 158:124-129. http://dx.doi.org/10.1016/j.virusres.2011.03.022.
-
(2011)
Virus Res
, vol.158
, pp. 124-129
-
-
Sakabe, S.1
Ozawa, M.2
Takano, R.3
Iwastuki-Horimoto, K.4
Kawaoka, Y.5
-
26
-
-
33846794619
-
Adaptation of an H7N7 equine influenza A virus in mice
-
Shinya K, Watanabe S, Ito T, Kasai N, Kawaoka Y. 2007. Adaptation of an H7N7 equine influenza A virus in mice. J Gen Virol 88:547-553. http://dx.doi.org/10.1099/vir.0.82411-0.
-
(2007)
J Gen Virol
, vol.88
, pp. 547-553
-
-
Shinya, K.1
Watanabe, S.2
Ito, T.3
Kasai, N.4
Kawaoka, Y.5
-
27
-
-
84862907725
-
Emergence of mammalian species-infectious and-pathogenic avian influenza H6N5 virus with no evidence of adaptation
-
Nam JH, Kim EH, Song D, Choi YK, Kim JK, Poo H. 2011. Emergence of mammalian species-infectious and-pathogenic avian influenza H6N5 virus with no evidence of adaptation. J Virol 85:13271-13277. http://dx.doi.org/10.1128/JVI.05038-11.
-
(2011)
J Virol
, vol.85
, pp. 13271-13277
-
-
Nam, J.H.1
Kim, E.H.2
Song, D.3
Choi, Y.K.4
Kim, J.K.5
Poo, H.6
-
28
-
-
0035811003
-
Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes
-
Brown EG, Liu H, Kit LC, Baird S, Nesrallah M. 2001. Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes. Proc Natl Acad Sci USA 98:6883-6888. http://dx.doi.org/10.1073/pnas.111165798.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6883-6888
-
-
Brown, E.G.1
Liu, H.2
Kit, L.C.3
Baird, S.4
Nesrallah, M.5
-
29
-
-
79959325749
-
The nucleoprotein and matrix protein segments of H5N1 influenza viruses are responsible for dominance in embryonated eggs
-
Shimizu K, Li C, Muramoto Y, Yamada S, Arikawa J, Chen H, Kawaoka Y. 2011. The nucleoprotein and matrix protein segments of H5N1 influenza viruses are responsible for dominance in embryonated eggs. J Gen Virol 92:1645-1649. http://dx.doi.org/10.1099/vir.0.030247-0.
-
(2011)
J Gen Virol
, vol.92
, pp. 1645-1649
-
-
Shimizu, K.1
Li, C.2
Muramoto, Y.3
Yamada, S.4
Arikawa, J.5
Chen, H.6
Kawaoka, Y.7
-
30
-
-
13044287344
-
Generation of influenza A viruses entirely from cloned cDNAs
-
Neumann G, Watanabe T, Ito H, Watanabe S, Goto H, Gao P, Hughes M, Perez DR, Donis R, Hoffmann E, Hobom G, Kawaoka Y. 1999. Generation of influenza A viruses entirely from cloned cDNAs. Proc Natl Acad Sci U S A 96:9345-9350. http://dx.doi.org/10.1073/pnas.96.16.9345.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 9345-9350
-
-
Neumann, G.1
Watanabe, T.2
Ito, H.3
Watanabe, S.4
Goto, H.5
Gao, P.6
Hughes, M.7
Perez, D.R.8
Donis, R.9
Hoffmann, E.10
Hobom, G.11
Kawaoka, Y.12
-
31
-
-
67249130012
-
The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit
-
Dias A, Bouvier D, Crépin T, McCarthy AA, Hart DJ, Baudin F, Cusack S, Ruigrok RW. 2009. The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit. Nature 458:914-918. http://dx.doi.org/10.1038/nature07745.
-
(2009)
Nature
, vol.458
, pp. 914-918
-
-
Dias, A.1
Bouvier, D.2
Crépin, T.3
McCarthy, A.A.4
Hart, D.J.5
Baudin, F.6
Cusack, S.7
Ruigrok, R.W.8
-
32
-
-
67249100913
-
Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
-
Yuan P, Bartlam M, Lou Z, Chen S, Zhou J, He X, Lv Z, Ge R, Li X, Deng T, Fodor E, Rao Z, Liu Y. 2009. Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Nature 458:909-913. http://dx.doi.org/10.1038/nature07720.
-
(2009)
Nature
, vol.458
, pp. 909-913
-
-
Yuan, P.1
Bartlam, M.2
Lou, Z.3
Chen, S.4
Zhou, J.5
He, X.6
Lv, Z.7
Ge, R.8
Li, X.9
Deng, T.10
Fodor, E.11
Rao, Z.12
Liu, Y.13
-
33
-
-
0028171260
-
Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds
-
Tomassini J, Selnick H, Davies ME, Armstrong ME, Baldwin J, Bourgeois M, Hastings J, Hazuda D, Lewis J, McClements W. 1994. Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds. Antimicrob Agents Chemother 38:2827-2837. http://dx.doi.org/10.1128/AAC.38.12.2827.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 2827-2837
-
-
Tomassini, J.1
Selnick, H.2
Davies, M.E.3
Armstrong, M.E.4
Baldwin, J.5
Bourgeois, M.6
Hastings, J.7
Hazuda, D.8
Lewis, J.9
McClements, W.10
-
34
-
-
0030053530
-
The amino-terminal one-third of the influenza virus PA protein is responsible for the induction of proteolysis
-
Sanz-Ezquerro JJ, Zürcher T, de la Luna S, Ortín J, Nieto A. 1996. The amino-terminal one-third of the influenza virus PA protein is responsible for the induction of proteolysis. J Virol 70:1905-1911.
-
(1996)
J Virol
, vol.70
, pp. 1905-1911
-
-
Sanz-Ezquerro, J.J.1
Zürcher, T.2
de la Luna, S.3
Ortín, J.4
Nieto, A.5
-
35
-
-
34248397190
-
Influenza virus infection causes specific degradation of the largest subunit of cellularRNApolymerase II
-
Rodriguez A, Pérez-González A, Nieto A. 2007. Influenza virus infection causes specific degradation of the largest subunit of cellularRNApolymerase II. J Virol 81:5315-5324. http://dx.doi.org/10.1128/JVI.02129-06.
-
(2007)
J Virol
, vol.81
, pp. 5315-5324
-
-
Rodriguez, A.1
Pérez-González, A.2
Nieto, A.3
-
36
-
-
4143148582
-
The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza A virusRNApolymerase complex
-
Fodor E, Smith M. 2004. The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza A virusRNApolymerase complex. J Virol 78:9144-9153. http://dx.doi.org/10.1128/JVI.78.17.9144-9153.2004.
-
(2004)
J Virol
, vol.78
, pp. 9144-9153
-
-
Fodor, E.1
Smith, M.2
-
37
-
-
0028039999
-
Complex structure of the nuclear translocation signal of influenza virus polymerase PA subunit
-
Nieto A, de la Luna S, Bárcena J, Portela A, Ortín J. 1994. Complex structure of the nuclear translocation signal of influenza virus polymerase PA subunit. J Gen Virol 75:29-36. http://dx.doi.org/10.1099/0022-1317-75-1-29.
-
(1994)
J Gen Virol
, vol.75
, pp. 29-36
-
-
Nieto, A.1
de la Luna, S.2
Bárcena, J.3
Portela, A.4
Ortín, J.5
-
38
-
-
40349113426
-
Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus
-
Gabriel G, Herwig A, Klenk HD. 2008. Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus. PLoS Pathog 4:e11. http://dx.doi.org/10.1371/journal.ppat.0040011.
-
(2008)
PLoS Pathog
, vol.4
-
-
Gabriel, G.1
Herwig, A.2
Klenk, H.D.3
-
39
-
-
78751622104
-
Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus
-
Gabriel G, Klingel K, Otte A, Thiele S, Hudjetz B, Arman-Kalcek G, Sauter M, Shmidt T, Rother F, Baumgarte S, Keiner B, Hartmann E, Bader M, Brownlee GG, Fodor E, Klenk HD. 2011. Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus. NatCommun2:156. http://dx.doi.org/10.1038/ncomms1158.
-
(2011)
Nat Commun
, vol.2
, pp. 156
-
-
Gabriel, G.1
Klingel, K.2
Otte, A.3
Thiele, S.4
Hudjetz, B.5
Arman-Kalcek, G.6
Sauter, M.7
Shmidt, T.8
Rother, F.9
Baumgarte, S.10
Keiner, B.11
Hartmann, E.12
Bader, M.13
Brownlee, G.G.14
Fodor, E.15
Klenk, H.D.16
-
40
-
-
33847624936
-
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit
-
Tarendeau F, Boudet J, Guilligay D, Mas PJ, Bougault CM, Boulo S, Baudin F, Ruigrok RW, Daigle N, Ellenberg J, Cusack S, Simorre JP, Hart DJ. 2007. Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit. Nat Struct Mol Biol 14:229-233. http://dx.doi.org/10.1038/nsmb1212.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 229-233
-
-
Tarendeau, F.1
Boudet, J.2
Guilligay, D.3
Mas, P.J.4
Bougault, C.M.5
Boulo, S.6
Baudin, F.7
Ruigrok, R.W.8
Daigle, N.9
Ellenberg, J.10
Cusack, S.11
Simorre, J.P.12
Hart, D.J.13
-
41
-
-
33745158157
-
A simple method of estimating fifty per cent endpoints
-
Reed LJ, Muench H. 1938. A simple method of estimating fifty per cent endpoints. Am J Epidemiol 27:493-497.
-
(1938)
Am J Epidemiol
, vol.27
, pp. 493-497
-
-
Reed, L.J.1
Muench, H.2
|