Plant-derived antifungal agent poacic acid targets β-1,3-glucan

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 12, 2015, Pages E1490-E1497

  Piotrowski, Jeff S ^a   Okada, Hiroki ^b   Lu, Fachuang ^a   Li, Sheena C ^c   Hinchman, Li ^a   Ranjan, Ashish ^a   Smith, Damon L ^a   Higbee, Alan J ^a   Ulbrich, Arne ^a   Coon, Joshua J ^a   Deshpande, Raamesh ^d   Bukhman, Yury V ^a   McIlwain, Sean ^a   Ong, Irene M ^a   Myers, Chad L ^d   Boonec, Charles ^c,e   Landicka, Robert ^a   Ralpha, John ^a   Kabbaged, Mehdi ^a   Ohyab, Yoshikazu ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c RIKEN Center for Sustainable Resource Science   (Japan)

^d University of Minnesota   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

Chemical genomics; Fungal cell wall; High dimensional morphometrics; Lignocellulosic hydrolysates; Saccharomyces cerevisiae

Indexed keywords

ANTIFUNGAL AGENT; BETA 1,3 GLUCAN; BIOFUEL; CASPOFUNGIN; FLUCONAZOLE; POACIC ACID; UNCLASSIFIED DRUG; BETA GLUCAN; BETA-1,3-GLUCAN; COUMARIC ACID; ECHINOCANDIN; FUNGICIDE; LIGNIN; LIGNOCELLULOSE; PLANT EXTRACT; STILBENE DERIVATIVE;

ALTERNARIA SOLANI; ARTICLE; BIOGENESIS; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG SYNTHESIS; DRUG TARGETING; FUNGAL CELL WALL; FUNGAL DEVELOPMENT; FUNGAL VIRULENCE; GENE DELETION; IN VITRO STUDY; IN VIVO STUDY; LYSIS; NONHUMAN; PHYTOPHTHORA SOJAE; POACEAE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SCLEROTINIA SCLEROTIORUM; TARGET CELL; CELL MEMBRANE; CELL WALL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG POTENTIATION; GENOMICS; HYDROLYSIS; IC50; METABOLISM;

ALTERNARIA SOLANI; FUNGI; PHYTOPHTHORA SOJAE; POACEAE; SACCHAROMYCES CEREVISIAE; SCLEROTINIA SCLEROTIORUM;

BETA-GLUCANS; CELL MEMBRANE; CELL WALL; COUMARIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ECHINOCANDINS; FUNGICIDES, INDUSTRIAL; GENOMICS; HYDROLYSIS; INHIBITORY CONCENTRATION 50; LIGNIN; PLANT EXTRACTS; POACEAE; SACCHAROMYCES CEREVISIAE; STILBENES;

EID: 84925426231     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1410400112     Document Type: Article

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