Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: The role of stress proteins ERdj5 and ERp57

British Journal of Cancer

Volumn 96, Issue 7, 2007, Pages 1062-1071

  Corazzari, M ^a   Lovat, P E ^b   Armstrong, J L ^c   Fimia, G M ^a   Hill, D S ^b   Birch Machin, M ^b   Redfern, C P F ^c   Piacentini, M ^a  

^a NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Fenretinide; Neuro ectodermal tumours

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ASCORBIC ACID; BORTEZOMIB; CALNEXIN; CALRETICULIN; FENRETINIDE; GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN; MESSENGER RNA; PROTEIN ERDJ5; PROTEIN ERP57; TEMOZOLOMIDE; THAPSIGARGIN; TRANSCRIPTION FACTOR ELF 2ALPHA; UNCLASSIFIED DRUG; VINCRISTINE; X BOX BINDING PROTEIN 1;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER SUSCEPTIBILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NEUROECTODERM TUMOR; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 4; ALTERNATIVE SPLICING; ANTINEOPLASTIC AGENTS; APOPTOSIS; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; FENRETINIDE; HUMANS; MOLECULAR CHAPERONES; NEUROBLASTOMA; NEUROECTODERMAL TUMORS; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN DISULFIDE-ISOMERASE; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 34247195447     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603672     Document Type: Article

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