Antenatal depression and antidepressants during pregnancy: Unraveling the complex interactions for the offspring

European Journal of Pharmacology

Volumn 753, Issue , 2015, Pages 257-262

  Olivier, Jocelien D A ^a,b,c   Åkerud, Helena ^a   Sundström Poromaa, Inger ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Antenatal depression; Antidepressants; Epigenetics; Neurodevelopment; Pregnancy; SSRI

Indexed keywords

GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; STRESS HORMONE; ANTIDEPRESSANT AGENT;

ANTENATAL DEPRESSION; ANXIETY DISORDER; ARTICLE; ATTENTION DISTURBANCE; AUTISM; BRAIN DEVELOPMENT; DEPRESSION; DISEASE ASSOCIATION; DNA METHYLATION; DRUG EFFECT; EPIGENETICS; EXECUTIVE FUNCTION; FETUS HEART RATE; FETUS RISK; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEART RATE VARIABILITY; HUMAN; INTELLIGENCE QUOTIENT; MATERNAL CARE; MATERNAL DISEASE; MATERNAL STRESS; MOOD; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PUERPERAL DEPRESSION; SALIVA LEVEL; SEX DIFFERENCE; VIOLENCE; ANIMAL; FEMALE; METABOLISM; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE; PSYCHOLOGY;

ANIMALS; ANTIDEPRESSIVE AGENTS; DEPRESSION; FEMALE; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS;

EID: 84925390807     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.07.049     Document Type: Article

References (94)

1. S.M. Abrams, T. Field, F. Scafidi, and M. Prodromidis Newborns of depressed mothers Infant Ment. Health J. 16 1995 233 239
2. L. Allister, B.M. Lester, S. Carr, and J. Liu The effects of maternal depression on fetal heart rate response to vibroacoustic stimulation Dev. Neuropsychol. 20 2001 639 651
3. J. Alonso, and J.P. Lepine Overview of key data from the European Study of the Epidemiology of Mental Disorders (ESEMeD) J. Clin. Psychiatry 68 Suppl. 2 2007 3 9
4. L. Andersson, I. Sundstrom-Poromaa, M. Bixo, M. Wulff, K. Bondestam, and M. aStrom Point prevalence of psychiatric disorders during the second trimester of pregnancy: a population-based study Am. J. Obstet. Gynecol. 189 2003 148 154
5. S.E. Andrade, M.A. Raebel, J. Brown, K. Lane, J. Livingston, D. Boudreau, S.J. Rolnick, D. Roblin, D.H. Smith, M.E. Willy, J.A. Staffa, and R. Platt Use of antidepressant medications during pregnancy: a multisite study Am. J. Obstet. Gynecol. 198 2008 194 195
6. M.P. Austin, D. Hadzi-Pavlovic, L. Leader, K. Saint, and G. Parker Maternal trait anxiety, depression and life event stress in pregnancy: relationships with infant temperament Early Hum. Dev. 81 2005 183 190
7. J.T. Barbey, and S.P. Roose SSRI safety in overdose J. Clin. Psychiatry 59 Suppl. 15 1998 42 48
8. E.D. Barker, S.R. Jaffee, R. Uher, and B. Maughan The contribution of prenatal and postnatal maternal anxiety and depression to child maladjustment Depress. Anxiety 28 2011 696 702
9. C.H. Bourke, Z.N. Stowe, and M.J. Owens Prenatal antidepressant exposure: clinical and preclinical findings Pharmacol. Rev. 66 2 2014 435 465
10. P.A. Brennan, R. Pargas, E.F. Walker, P. Green, D.J. Newport, and Z. Stowe Maternal depression and infant cortisol: influences of timing, comorbidity and treatment J. Child Psychol. Psychiatry 49 2008 1099 1107
11. R.C. Casper, B.E. Fleisher, J.C. Lee-Ancajas, A. Gilles, E. Gaylor, A. DeBattista, and H.E. Hoyme Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy J. Pediatr. 142 2003 402 408
12. W.O. Cooper, M.E. Willy, S.J. Pont, and W.A. Ray Increasing use of antidepressants in pregnancy Am. J. Obstet. Gynecol. 196 2007 544 545
13. L.A. Croen, J.K. Grether, C.K. Yoshida, R. Odouli, and V. Hendrick Antidepressant use during pregnancy and childhood autism spectrum disorders Arch. Gen. Psychiatry 68 2011 1104 1112
14. E.P. Davis, L.M. Glynn, C.D. Schetter, C. Hobel, A. Chicz-Demet, and C.A. Sandman Prenatal exposure to maternal depression and cortisol influences infant temperament J. Am. Acad. Child Adolesc. Psychiatry 46 2007 737 746
15. E.P. Davis, L.M. Glynn, F. Waffarn, and C.A. Sandman Prenatal maternal stress programs infant stress regulation J. Child Psychol. Psychiatry 52 2011 119 129
16. E.P. Davis, N. Snidman, P.D. Wadhwa, L.M. Glynn, C.D. Schetter, and C.A. Sandman Prenatal maternal anxiety and depression predict negative behavioral reactivity in infacy Infancy 6 2004 319 331
17. T. Deave, J. Heron, J. Evans, and A. Emond The impact of maternal depression in pregnancy on early child development BJOG 115 2008 1043 1051
18. M.A. Diego, T. Field, M. Hernandez-Reif, C. Cullen, S. Schanberg, and C. Kuhn Prepartum, postpartum, and chronic depression effects on newborns Psychiatry 67 2004 63 80
19. J.A. DiPietro, M.F. Novak, K.A. Costigan, L.D. Atella, and S.P. Reusing Maternal psychological distress during pregnancy in relation to child development at age two Child Dev. 77 2006 573 587
20. H. El Marroun, V.W. Jaddoe, J.J. Hudziak, S.J. Roza, E.A. Steegers, A. Hofman, F.C. Verhulst, T.J. White, B.H. Stricker, and H. Tiemeier Maternal use of selective serotonin reuptake inhibitors, fetal growth, and risk of adverse birth outcomes Arch. Gen. Psychiatry 69 2012 706 714
21. L.M. Ellman, C.D. Schetter, C.J. Hobel, A. Chicz-Demet, L.M. Glynn, and C.A. Sandman Timing of fetal exposure to stress hormones: effects on newborn physical and neuromuscular maturation Dev. Psychobiol. 50 2008 232 241
22. E.K. Emory, and J.N. Dieter Maternal depression and psychotropic medication effects on the human fetus Ann. NY Acad. Sci. 1094 2006 287 291
23. T. Field, and M. Diego Cortisol: the culprit prenatal stress variable Int. J. Neurosci. 118 2008 1181
24. T. Field, M. Diego, J. Dieter, M. Hernandez-Reif, S. Schanberg, C. Kuhn, R. Yando, and D. Bendell Prenatal depression effects on the fetus and the newborn Infant Behav. Dev. 27 2004 216 229
25. T. Field, M. Diego, M. Hernandez-Reif, B. Figueiredo, S. Schanberg, and C. Kuhn Sleep disturbances in depressed pregnant women and their newborns Infant Behav. Dev. 30 2007 127 133
26. T. Field, M. Diego, M. Hernandez-Reif, Y. Vera, K. Gil, S. Schanberg, C. Kuhn, and A. Gonzalez-Garcia Prenatal maternal biochemistry predicts neonatal biochemistry Int. J. Neurosci. 114 2004 933 945
27. R. Gitau, A. Cameron, N.M. Fisk, and V. Glover Fetal exposure to maternal cortisol Lancet 352 1998 707 708
28. V. Glover Maternal depression, anxiety and stress during pregnancy and child outcome; what needs to be done Best Pract. Res. Clin. Obstet. Gynaecol. 28 2014 25 35
29. M.V. Gomes, and G.G. Pelosi Epigenetic vulnerability and the environmental influence on health Exp. Biol. Med. 238 2013 859 865
30. L.L. Gorman, M.W. O'Hara, B. Figueiredo, S. Hayes, F. Jacquemain, M.H. Kammerer, C.M. Klier, S. Rosi, G. Seneviratne, and A.L. Sutter-Dallay Adaptation of the structured clinical interview for DSM-IV disorders for assessing depression in women during pregnancy and post-partum across countries and cultures Br. J. Psychiatry Suppl. 46 2004 S17 S23
31. N.K. Grote, J.A. Bridge, A.R. Gavin, J.L. Melville, S. Iyengar, and W.J. Katon A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction Arch. Gen. Psychiatry 67 2010 1012 1024
32. G.E. Hanley, and T.F. Oberlander Neurodevelopmental outcomes following prenatal exposure to serotonin reuptake inhibitor antidepressants: a "social teratogen" or moderator of developmental risk? Birth Defects Res. A: Clin. Mol. Teratol. 94 2012 651 659
33. D.F. Hay, S. Pawlby, C.S. Waters, O. Perra, and D. Sharp Mothers' antenatal depression and their children's antisocial outcomes Child Dev. 81 2010 149 165
34. D.F. Hay, S. Pawlby, C.S. Waters, and D. Sharp Antepartum and postpartum exposure to maternal depression: different effects on different adolescent outcomes J. Child Psychol. Psychiatry 49 2008 1079 1088
35. R.M. Hayes, P. Wu, R.C. Shelton, W.O. Cooper, W.D. Dupont, E. Mitchel, and T.V. Hartert Maternal antidepressant use and adverse outcomes: a cohort study of 228,876 pregnancies Am. J. Obstet. Gynecol. 207 2012 49
36. C. Hellgren, H. Åkerud, A. kalkidou, and I. Sundström-Poromaa Cortisol awakening response in late pregnancy in women with previous or ongoing depression Psychoneuroendocrinology 38 2013 3150 3154
37. J. Henrichs, J.J. Schenk, S.J. Roza, M.P. van den Berg, H.G. Schmidt, E.A. Steegers, A. Hofman, V.W. Jaddoe, F.C. Verhulst, and H. Tiemeier Maternal psychological distress and fetal growth trajectories: the Generation R Study Psychol. Med. 40 2010 633 643
38. A. Hostetter, Z.N. Stowe, J.R. Strader Jr.; E. McLaughlin, and A. Llewellyn Dose of selective serotonin uptake inhibitors across pregnancy: clinical implications Depress. Anxiety 11 2000 51 57
39. A.C. Huizink, P.G. Robles de Medina, E.J. Mulder, G.H. Visser, and J.K. Buitelaar Stress during pregnancy is associated with developmental outcome in infancy J. Child Psychol. Psychiatry 44 2003 810 818
40. L.A. Kaplan, L. Evans, and C. Monk Effects of mothers' prenatal psychiatric status and postnatal caregiving on infant biobehavioral regulation: can prenatal programming be modified? Early Hum. Dev. 84 2008 249 256
41. R.C. Kessler, P. Berglund, O. Demler, R. Jin, K.R. Merikangas, and E.E. Walters Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication Arch. Gen. Psychiatry 62 2005 593 602
42. R.C. Kessler, K.A. McGonagle, S. Zhao, C.B. Nelson, M. Hughes, S. Eshleman, H.U. Wittchen, and K.S. Kendler Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey Arch. Gen. Psychiatry 51 1994 8 19
43. H. Kieler, M. Artama, A. Engeland, O. Ericsson, K. Furu, M. Gissler, R.B. Nielsen, M. Norgaard, O. Stephansson, U. Valdimarsdottir, H. Zoega, and B. Haglund Selective serotonin reuptake inhibitors during pregnancy and risk of persistent pulmonary hypertension in the newborn: population based cohort study from the five Nordic countries BMJ 344 2012 d8012
44. J.G. Lewis, C.J. Bagley, P.A. Elder, A.W. Bachmann, and D.J. Torpy Plasma free cortisol fraction reflects levels of functioning corticosteroid-binding globulin Clin. Chim. Acta 359 2005 189 194
45. A.M. Loughhead, A.D. Fisher, D.J. Newport, J.C. Ritchie, M.J. Owens, C.L. DeVane, and Z.N. Stowe Antidepressants in amniotic fluid: another route of fetal exposure Am. J. Psychiatry 163 2006 145 147
46. B.L. Lundy, N.A. Jones, T. Field, G. Nearing, M. Davalos, P.A. Pietro, S. Schanberg, and C. Kuhn Prenatal depression effects on neonates Infant Behav. Dev. 22 1999 119 129
47. X.H. Ma, W.X. Wu, and P.W. Nathanielsz Gestation-related and betamethasone-induced changes in 11beta-hydroxysteroid dehydrogenase types 1 and 2 in the baboon placenta Am. J. Obstet. Gynecol. 188 2003 13 21
48. R.A. Mancuso, C.D. Schetter, C.M. Rini, S.C. Roesch, and C.J. Hobel Maternal prenatal anxiety and corticotropin-releasing hormone associated with timing of delivery Psychosom. Med. 66 2004 762 769
49. S.M. Marcus Depression during pregnancy: rates, risks and consequences - Motherisk Update 2008 Can. J. Clin. Pharmacol. 16 2009 e15 e22
50. M. McLean, A. Bisits, J. Davies, R. Woods, P. Lowry, and R. Smith A placental clock controlling the length of human pregnancy Nat. Med. 1 1995 460 463
51. J.L. Melville, A. Gavin, Y. Guo, M.Y. Fan, and W.J. Katon Depressive disorders during pregnancy: prevalence and risk factors in a large urban sample Obstet. Gynecol. 116 2010 1064 1070
52. M. Mennes, P. Stiers, L. Lagae, and B. Van den Bergh Long-term cognitive sequelae of antenatal maternal anxiety: involvement of the orbitofrontal cortex Neurosci. Biobehav. Rev. 30 2006 1078 1086
53. L.J. Miller, and E.M. LaRusso Preventing postpartum depression Psychiatr. Clin. North Am. 34 2011 53 65
54. S. Misri, P. Reebye, K. Kendrick, D. Carter, D. Ryan, R.E. Grunau, and T.F. Oberlander Internalizing behaviors in 4-year-old children exposed in utero to psychotropic medications Am. J. Psychiatry 163 2006 1026 1032
55. C. Monk, W.P. Fifer, M.M. Myers, E. Bagiella, J.K. Duong, I.S. Chen, L. Leotti, and A. Altincatal Effects of maternal breathing rate, psychiatric status, and cortisol on fetal heart rate Dev. Psychobiol. 53 2011 221 233
56. C. Monk, R.P. Sloan, M.M. Myers, L. Ellman, E. Werner, J. Jeon, F. Tager, and W.P. Fifer Fetal heart rate reactivity differs by women's psychiatric status: an early marker for developmental risk? J. Am. Acad. Child Adolesc. Psychiatry 43 2004 283 290
57. J.T. Mortensen, J. Olsen, H. Larsen, J. Bendsen, C. Obel, and H.T. Sorensen Psychomotor development in children exposed in utero to benzodiazepines, antidepressants, neuroleptics, and anti-epileptics Eur. J. Epidemiol. 18 2003 769 771
58. E.J. Mulder, F.F. Ververs, H.R. de, and G.H. Visser Selective serotonin reuptake inhibitors affect neurobehavioral development in the human fetus Neuropsychopharmacology 36 2011 1961 1971
59. V.E. Murphy, and V.L. Clifton Alterations in human placental 11beta-hydroxysteroid dehydrogenase type 1 and 2 with gestational age and labour Placenta 24 2003 739 744
60. E.J. Nestler Epigenetic mechanisms of depression JAMA Psychiatry 71 2014 454 456
61. I. Nulman, J. Rovet, D.E. Stewart, J. Wolpin, H.A. Gardner, J.G. Theis, N. Kulin, and G. Koren Neurodevelopment of children exposed in utero to antidepressant drugs N. Engl. J. Med. 336 1997 258 262
62. I. Nulman, J. Rovet, D.E. Stewart, J. Wolpin, P. Pace-Asciak, S. Shuhaiber, and G. Koren Child development following exposure to tricyclic antidepressants or fluoxetine throughout fetal life: a prospective, controlled study Am. J. Psychiatry 159 2002 1889 1895
63. T.G. O'Connor, P. Caprariello, E.R. Blackmore, A.M. Gregory, V. Glover, and P. Fleming Prenatal mood disturbance predicts sleep problems in infancy and toddlerhood Early Hum. Dev. 83 2007 451 458
64. T.G. O'Connor, J. Heron, and V. Glover Antenatal anxiety predicts child behavioral/emotional problems independently of postnatal depression J. Am. Acad. Child Adolesc. Psychiatry 41 2002 1470 1477
65. T.F. Oberlander, G.R. Eckstein, C. Fitzgerald, A.L. Ellwood, S. Misri, D. Rurak, and K.W. Riggs Prolonged prenatal psychotropic medication exposure alters neonatal acute pain response Pediatr. Res. 51 2002 443 453
66. T.F. Oberlander, R. Grunau, L. Mayes, W. Riggs, D. Rurak, M. Papsdorf, S. Misri, and J. Weinberg Hypothalamic-pituitary-adrenal (HPA) axis function in 3-month old infants with prenatal selective serotonin reuptake inhibitor (SSRI) antidepressant exposure Early Hum. Dev. 84 2008 689 697
67. T.F. Oberlander, R.E. Grunau, C. Fitzgerald, M. Papsdorf, D. Rurak, and W. Riggs Pain reactivity in 2-month-old infants after prenatal and postnatal serotonin reuptake inhibitor medication exposure Pediatrics 115 2005 411 425
68. T.F. Oberlander, M. Papsdorf, U.M. Brain, S. Misri, C. Ross, and R.E. Grunau Prenatal effects of selective serotonin reuptake inhibitor antidepressants, serotonin transporter promoter genotype (SLC6A4), and maternal mood on child behavior at 3 years of age Arch. Pediatr. Adolesc. Med. 164 2010 444 451
69. T.F. Oberlander, P. Reebye, S. Misri, M. Papsdorf, J. Kim, and R.E. Grunau Externalizing and attentional behaviors in children of depressed mothers treated with a selective serotonin reuptake inhibitor antidepressant during pregnancy Arch. Pediatr. Adolesc. Med. 161 2007 22 29
70. J.D. Olivier, H. Akerud, H. Kaihola, J.L. Pawluski, A. Skalkidou, U. Hogberg, and I. Sundstrom-Poromaa The effects of maternal depression and maternal selective serotonin reuptake inhibitor exposure on offspring Front. Cell. Neurosci. 7 2013 73
71. A.A. Patkar, L. Bilal, and P.S. Masand Pharmacotherapy of depression in pregnancy Ann. Clin. Psychiatry 16 2004 87 100
72. S. Pawlby, D. Hay, D. Sharp, C.S. Waters, and C.M. Pariante Antenatal depression and offspring psychopathology: the influence of childhood maltreatment Br. J. Psychiatry 199 2011 106 112
73. S. Pawlby, D.F. Hay, D. Sharp, C.S. Waters, and V. O'Keane Antenatal depression predicts depression in adolescent offspring: prospective longitudinal community-based study J. Affect. Disord. 113 2009 236 243
74. J.L. Pawluski, U.M. Brain, C.M. Underhill, G.L. Hammond, and T.F. Oberlander Prenatal SSRI exposure alters neonatal corticosteroid binding globulin, infant cortisol levels, and emerging HPA function Psychoneuroendocrinology 37 2012 1019 1028
75. R.M. Pearson, J. Evans, D. Kounali, G. Lewis, J. Heron, P.G. Ramchandani, T.G. O'Connor, and A. Stein Maternal depression during pregnancy and the postnatal period: risks and possible mechanisms for offspring depression at age 18 years JAMA Psychiatry 70 2013 1312 1319
76. D. Rai, B.K. Lee, C. Dalman, J. Golding, G. Lewis, and C. Magnusson Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study BMJ 346 2013 f2059
77. D. Ryan, L. Milis, and N. Misri Depression during pregnancy Can. Fam. Physician 51 2005 1087 1093
78. C.A. Sandman, P.D. Wadhwa, A. Chicz-Demet, M. Porto, and T.J. Garite Maternal corticotropin-releasing hormone and habituation in the human fetus Dev. Psychobiol. 34 1999 163 173
79. G.E. Simon, M.L. Cunningham, and R.L. Davis Outcomes of prenatal antidepressant exposure Am. J. Psychiatry 159 2002 2055 2061
80. P.M. Stewart, F.M. Rogerson, and J.I. Mason Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis J. Clin. Endocrinol. Metab. 80 1995 885 890
81. R.C. Stewart Maternal depression and infant growth: a review of recent evidence Matern. Child Nutr. 3 2007 94 107
82. L.V. Toffoli, G.M. Rodrigues Jr.; J.F. Oliveira, A.S. Silva, E.G. Moreira, G.G. Pelosi, and M.V. Gomes Maternal exposure to fluoxetine during gestation and lactation affects the DNA methylation programming of rat's offspring: modulation by folic acid supplementation Behav. Brain Res. 265 2014 142 147
83. R. Uher Gene-environment interactions in severe mental illness Front. Psychiatry 5 2014 48
84. T. Van Batenburg-Eddes, M.J. Brion, J. Henrichs, V.W. Jaddoe, A. Hofman, F.C. Verhulst, D.A. Lawlor, S.G. Davey, and H. Tiemeier Parental depressive and anxiety symptoms during pregnancy and attention problems in children: a cross-cohort consistency study J. Child Psychol. Psychiatry 54 2012 591 600
85. P.D. Wadhwa, C. Dunkel-Schetter, A. Chicz-Demet, M. Porto, and C.A. Sandman Prenatal psychosocial factors and the neuroendocrine axis in human pregnancy Psychosom. Med. 58 1996 432 446
86. I.C. Weaver, N. Cervoni, F.A. Champagne, A.C. D'Alessio, S. Sharma, J.R. Seckl, S. Dymov, M. Szyf, and M.J. Meaney Epigenetic programming by maternal behavior Nat. Neurosci. 7 2004 847 854
87. W.M. Weikum, U. Brain, C.M. Chau, R.E. Grunau, W.T. Boyce, A. Diamond, and T.F. Oberlander Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age Front. Cell. Neurosci. 7 2013 180
88. W.M. Weikum, L.C. Mayes, R.E. Grunau, U. Brain, and T.F. Oberlander The impact of prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and maternal mood on mother-infant interactions at 3 months of age Infant Behav. Dev. 36 2013 485 493
89. W.M. Weikum, T.F. Oberlander, T.K. Hensch, and J.F. Werker Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception Proc. Natl. Acad. Sci. USA 109 Suppl. 2 2012 S17221 S17227
90. M. Weinstock The potential influence of maternal stress hormones on development and mental health of the offspring Brain Behav. Immun. 19 2005 296 308
91. E.A. Werner, M.M. Myers, W.P. Fifer, B. Cheng, Y. Fang, R. Allen, and C. Monk Prenatal predictors of infant temperament Dev. Psychobiol. 49 2007 474 484
92. WHO The Global Burden of Disease: 2004 Update 2004 1
93. P.S. Zeskind, and L.E. Stephens Maternal selective serotonin reuptake inhibitor use during pregnancy and newborn neurobehavior Pediatrics 113 2004 368 375
94. B. Zuckerman, H. Bauchner, S. Parker, and H. Cabral Maternal depressive symptoms during pregnancy, and newborn irritability J. Dev. Behav. Pediatr. 11 1990 190 194