Internalizing behaviors in 4-year-old children exposed in utero to psychotropic medications

American Journal of Psychiatry

Volumn 163, Issue 6, 2006, Pages 1026-1032

  Misri, Shaila ^a   Reebye, Pratibha ^b   Kendrick, Kristin ^b   Carter, Diana ^b   Ryan, Deirdre ^b   Grunau, Ruth E ^b   Oberlander, Tim F ^b  

^a ST PAUL S HOSPITAL   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CLONAZEPAM; FLUOXETINE; PAROXETINE; PSYCHOTROPIC AGENT; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ANXIETY; ARTICLE; CHILD BEHAVIOR; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; HUMAN; MOOD; MOTHER CHILD RELATION; PRENATAL DRUG EXPOSURE; PRESCHOOL CHILD; PRIORITY JOURNAL; PSYCHOSOCIAL WITHDRAWAL; ADULT; AFFECT; AGE; ANXIETY DISORDER; BEHAVIOR DISORDER; CHEMICALLY INDUCED DISORDER; CHILD; COHORT ANALYSIS; COMPARATIVE STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; FETOMATERNAL TRANSFUSION; MOTHER; PREGNANCY; PRENATAL EXPOSURE; PSYCHOLOGICAL ASPECT; REPRODUCIBILITY; STATISTICAL MODEL;

ADULT; AFFECT; AGE FACTORS; ANXIETY DISORDERS; CHILD BEHAVIOR DISORDERS; CHILD OF IMPAIRED PARENTS; CHILD, PRESCHOOL; COHORT STUDIES; DEPRESSIVE DISORDER; FEMALE; HUMANS; LOGISTIC MODELS; MATERNAL EXPOSURE; MATERNAL-FETAL EXCHANGE; MOTHER-CHILD RELATIONS; MOTHERS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PSYCHOTROPIC DRUGS; REPRODUCIBILITY OF RESULTS;

EID: 85047697473     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.2006.163.6.1026     Document Type: Article

References (20)

1. Evans J, Heron J, Francomb H, Oke S, Golding J: Cohort study of depressed mood during pregnancy and after childbirth. BMJ 2001; 323:257-260
2. Weissman MM, Wolk S, Wickramaratne P, Goldstein RB, Adams P, Greenwald S, Ryan ND, Dahl RE, Steinberg D: Children with prepubertal-onset major depressive disorder and anxiety grown up. Arch Gen Psychiatry 1999; 56:794-801
3. Ansorge MS, Zhou M, Lira A, Hen R, Gingrich JA: Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science 2004; 306:879-881
4. Oberlander TF, Misri S, Fitzgerald CE, Kostaras X, Rurak D, Riggs W: Pharmacologic factors associated with transient neonatal symptoms following prenatal psychotropic medication exposure. J Clin Psychiatry 2004; 65:230-237
5. Murray L, Fiori-Cowley A, Hooper R: The impact of postnatal depression and associated adversity on early mother-infant interactions and later infant outcome. Child Dev 1996; 67:2512-2526
6. Cohn JF, Tronick EZ: Specificity of infants' response to mothers' affective behavior. J Am Acad Child Adolesc Psychiatry 1989; 28:242-248
7. Cohn JF, Tronick EZ: Three-month-old infants' reaction to simulated maternal depression. Child Dev 1983; 54:185-193
8. Whiffen VE, Gotlib IH: Infants of postpartum depressed mothers: temperament and cognitive status. J Abnorm Psychol 1989; 98:274-279
9. Hay DF, Pawlby S, Angold A, Harold GT, Sharp D: Pathways to violence in the children of mothers who were depressed postpartum. Dev Psychol 2003; 39:1083-1094
10. Field T, Lang C, Martinez A, Yando R, Pickens J, Bendell D: Preschool follow up of children of dysphoric mothers. J Clin Child Psychol 1996; 25:275-279
11. O'Connor TG, Heron J, Golding J, Beveridge M, Glover V: Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years: report from the Avon longitudinal study of parents and children. Br J Psychiatry 2002; 180:502-508
12. Nulman I, Rovet J, Stewart DE, Wolpin J, Gardner HA, Theis JGW, Kulin N, Koren G: Neurodevelopment of children exposed in utero to antidepressant drugs. N Engl J Med 1997; 336:258-262
13. Nulman I, Rovet J, Stewart DE, Wolpin J, Pace-Asciak P, Shuhaiber S, Koren G: Child development following exposure to tricyclic antidepressants or fluoxetine throughout fetal life: a prospective, controlled study. Am J Psychiatry 2002; 159:1889-1895
14. Achenbach TM, Rescorla LA: Manual for the ASEBA Preschool Forms & Profiles. Burlington, University of Vermont Research Center for Children, Youth, & Families, 2001
15. Mattson S, Eastvold A, Jones K, Harris J, Chambers C: Neurobehavioral follow-up of children prenatally exposed to fluoxetine. Teratology 1999; 59:376
16. Casper RC, Fleisher BE, Lee-Ancajas JC, Gilles A, Gaylor E, DeBattista A, Hoyme HE: Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy. J Pediatr 2003; 142:402-408
17. Murray L, Hipwell A, Hooper R, Stein A, Cooper P: The cognitive development of 5-year-old children of postnatally depressed mothers. J Child Psychol Psychiatry 1996; 37:927-935
18. Van den Bergh BRH, Marcoen A: High antenatal anxiety is related to ADHD symptoms, externalizing problems, and anxiety in 8- and 9-year-olds. Child Dev 2004; 75:1085-1097
19. Misri S, Oberlander T, Fairbrother N, Carter D, Ryan D, Kuan AJ, Reebye P: Relation between prenatal maternal mood and anxiety and neonatal health. Can J Psychiatry 2004; 49:684-689
20. Reebye PN, Morison SJ, Panikkar H, Misri S, Grunau RE: Affect expression in prenatally exposed and nonexposed mother-infant dyads. Infant Ment Health J 2002; 23:403-416