Nucleofection of rat pheochromocytoma PC-12 cells with human mutated beta-amyloid precursor protein gene (app-sw) leads to reduced viability, autophagy-like process, and increased expression and secretion of beta amyloid

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Pająk, Beata ^a   Kania, Elzbieta ^a   Orzechowski, Arkadiusz ^a,b  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^b WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID PRECURSOR PROTEIN; AMYLOID BETA PROTEIN;

ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DAMAGE; CELL DEATH; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; DIFFERENTIATION; GENE DELETION; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MULTIVESICULAR BODY; NECROSIS; NONHUMAN; PHEOCHROMOCYTOMA; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; ANIMAL; CELL NUCLEUS; CELL SURVIVAL; EXPERIMENTAL NEOPLASM; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; PC12 CELL LINE; PROCEDURES; TREATMENT OUTCOME; UPREGULATION;

RATTUS;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; AUTOPHAGY; CELL NUCLEUS; CELL SURVIVAL; GENETIC THERAPY; NEOPLASMS, EXPERIMENTAL; PC12 CELLS; RATS; TRANSFECTION; TREATMENT OUTCOME; UP-REGULATION;

EID: 84925324916     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/746092     Document Type: Article

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